Trait: angina pectoris

Experimental Factor Ontology (EFO) Information
Identifier EFO_0003913
Description
  • The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
Trait category
Other trait
Synonyms 4 synonyms
  • Angor Pectoris
  • Stenocardia
  • Stenocardias
  • stable angina
Mapped term(s) 7 mapped terms
  • ICD10:I20
  • ICD9:413
  • MeSH:D000787
  • MeSH:D060050
  • NCIt:C66914
  • SNOMEDCT:194828000
  • SNOMEDCT:233819005

Associated Polygenic Score(s)

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Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution PGS Scoring File (FTP Link)
PGS000703
(HC132)
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Angina angina pectoris 183,692
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http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000703/ScoringFiles/PGS000703.txt.gz - Check Terms/Licenses

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM001595 PGS000703
(HC132)
PSS000794|
European Ancestry|
87,413 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Angina AUROC: 0.59262 Age, sex, PCs(1-10)

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000794 87,413 individuals European UKB