Trait: bone quantitative ultrasound measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0004514
Description A bone quantitative ultrasound measurement is the output of a an ultrasound process in which bones are assayed using ultrasound and information about bone density, cortical thickness, elasticity and microarchitecture may be returned.
Trait category
Other measurement
Synonyms 2 synonyms
  • bone quantitative ultrasound
  • broadband ultrasound attenuation

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000951
(GBE_INI3144)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Heel Broadband ultrasound attenuation, direct entry bone quantitative ultrasound measurement 13,735
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000951/ScoringFiles/PGS000951.txt.gz
PGS000952
(GBE_INI3147)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Heel quantitative ultrasound index (QUI), direct entry bone quantitative ultrasound measurement 14,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000952/ScoringFiles/PGS000952.txt.gz
PGS000953
(GBE_INI4101)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Left heel broadband ultrasound attenuation bone quantitative ultrasound measurement 7,688
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000953/ScoringFiles/PGS000953.txt.gz
PGS000954
(GBE_INI4104)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Left heel quantitative ultrasound index (QUI), direct entry bone quantitative ultrasound measurement 9,272
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000954/ScoringFiles/PGS000954.txt.gz
PGS000955
(GBE_INI4120)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Right heel broadband ultrasound attenuation bone quantitative ultrasound measurement 7,069
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000955/ScoringFiles/PGS000955.txt.gz
PGS000956
(GBE_INI4123)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Right heel quantitative ultrasound index (QUI), direct entry bone quantitative ultrasound measurement 9,756
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000956/ScoringFiles/PGS000956.txt.gz
PGS003536
(cont-decay-log_heel_BUA)
 PGP000457 |
Ding Y et al. Nature (2023)
 Heel Broadband ultrasound attenuation, direct entry bone quantitative ultrasound measurement 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003536/ScoringFiles/PGS003536.txt.gz
PGS004413
(X3144.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Heel Broadband ultrasound attenuation, direct entry bone quantitative ultrasound measurement 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004413/ScoringFiles/PGS004413.txt.gz
PGS004414
(X3147.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Heel quantitative ultrasound index (QUI), direct entry bone quantitative ultrasound measurement 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004414/ScoringFiles/PGS004414.txt.gz
PGS004417
(X4101.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Heel broadband ultrasound attenuation (left) bone quantitative ultrasound measurement 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004417/ScoringFiles/PGS004417.txt.gz
PGS004418
(X4104.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Heel quantitative ultrasound index (QUI), direct entry (left) bone quantitative ultrasound measurement 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004418/ScoringFiles/PGS004418.txt.gz
PGS004422
(X4120.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Heel broadband ultrasound attenuation (right) bone quantitative ultrasound measurement 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004422/ScoringFiles/PGS004422.txt.gz
PGS004423
(X4123.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Heel quantitative ultrasound index (QUI), direct entry (right) bone quantitative ultrasound measurement 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004423/ScoringFiles/PGS004423.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007579 PGS000951
(GBE_INI3144)
 PSS007226|
African Ancestry|
2,252 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — R²: 0.03865 [0.02946, 0.04783]
Incremental R2 (full-covars): 0.01472
PGS R2 (no covariates): 0.01564 [0.00966, 0.02163]		 age, sex, UKB array type, Genotype PCs —
PPM007580 PGS000951
(GBE_INI3144)
 PSS007227|
East Asian Ancestry|
795 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — R²: 0.09355 [0.06728, 0.11982]
Incremental R2 (full-covars): 0.05152
PGS R2 (no covariates): 0.05375 [0.03296, 0.07454]		 age, sex, UKB array type, Genotype PCs —
PPM007581 PGS000951
(GBE_INI3144)
 PSS007228|
European Ancestry|
12,376 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — R²: 0.1963 [0.18746, 0.20514]
Incremental R2 (full-covars): 0.11678
PGS R2 (no covariates): 0.11778 [0.11026, 0.1253]		 age, sex, UKB array type, Genotype PCs —
PPM007582 PGS000951
(GBE_INI3144)
 PSS007229|
South Asian Ancestry|
2,312 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — R²: 0.09722 [0.08476, 0.10969]
Incremental R2 (full-covars): 0.05231
PGS R2 (no covariates): 0.05582 [0.04594, 0.06569]		 age, sex, UKB array type, Genotype PCs —
PPM007583 PGS000951
(GBE_INI3144)
 PSS007230|
European Ancestry|
38,830 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — R²: 0.20634 [0.2009, 0.21179]
Incremental R2 (full-covars): 0.11895
PGS R2 (no covariates): 0.11837 [0.11379, 0.12295]		 age, sex, UKB array type, Genotype PCs —
PPM007584 PGS000952
(GBE_INI3147)
 PSS007236|
African Ancestry|
2,253 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry — — R²: 0.03462 [0.02589, 0.04335]
Incremental R2 (full-covars): 0.01756
PGS R2 (no covariates): 0.01829 [0.01183, 0.02474]		 age, sex, UKB array type, Genotype PCs —
PPM007585 PGS000952
(GBE_INI3147)
 PSS007237|
East Asian Ancestry|
795 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry — — R²: 0.09836 [0.07157, 0.12516]
Incremental R2 (full-covars): 0.06627
PGS R2 (no covariates): 0.06933 [0.04611, 0.09255]		 age, sex, UKB array type, Genotype PCs —
PPM007586 PGS000952
(GBE_INI3147)
 PSS007238|
European Ancestry|
12,376 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry — — R²: 0.18809 [0.17935, 0.19684]
Incremental R2 (full-covars): 0.13505
PGS R2 (no covariates): 0.13677 [0.12885, 0.1447]		 age, sex, UKB array type, Genotype PCs —
PPM007587 PGS000952
(GBE_INI3147)
 PSS007239|
South Asian Ancestry|
2,312 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry — — R²: 0.10193 [0.08923, 0.11462]
Incremental R2 (full-covars): 0.06757
PGS R2 (no covariates): 0.07119 [0.06022, 0.08216]		 age, sex, UKB array type, Genotype PCs —
PPM007588 PGS000952
(GBE_INI3147)
 PSS007240|
European Ancestry|
38,834 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry — — R²: 0.1966 [0.19122, 0.20198]
Incremental R2 (full-covars): 0.1419
PGS R2 (no covariates): 0.14158 [0.13671, 0.14646]		 age, sex, UKB array type, Genotype PCs —
PPM007591 PGS000953
(GBE_INI4101)
 PSS007278|
European Ancestry|
10,636 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel broadband ultrasound attenuation (L) — — R²: 0.18344 [0.17475, 0.19212]
Incremental R2 (full-covars): 0.09737
PGS R2 (no covariates): 0.09704 [0.09006, 0.10403]		 age, sex, UKB array type, Genotype PCs —
PPM007589 PGS000953
(GBE_INI4101)
 PSS007276|
African Ancestry|
3,559 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel broadband ultrasound attenuation (L) — — R²: 0.03758 [0.02851, 0.04665]
Incremental R2 (full-covars): 0.00859
PGS R2 (no covariates): 0.00936 [0.0047, 0.01402]		 age, sex, UKB array type, Genotype PCs —
PPM007590 PGS000953
(GBE_INI4101)
 PSS007277|
East Asian Ancestry|
781 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel broadband ultrasound attenuation (L) — — R²: 0.10345 [0.07612, 0.13077]
Incremental R2 (full-covars): 0.07295
PGS R2 (no covariates): 0.07189 [0.0483, 0.09547]		 age, sex, UKB array type, Genotype PCs —
PPM007592 PGS000953
(GBE_INI4101)
 PSS007279|
South Asian Ancestry|
5,043 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel broadband ultrasound attenuation (L) — — R²: 0.08632 [0.07443, 0.0982]
Incremental R2 (full-covars): 0.04895
PGS R2 (no covariates): 0.04892 [0.03961, 0.05823]		 age, sex, UKB array type, Genotype PCs —
PPM007593 PGS000953
(GBE_INI4101)
 PSS007280|
European Ancestry|
25,716 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel broadband ultrasound attenuation (L) — — R²: 0.19239 [0.18705, 0.19774]
Incremental R2 (full-covars): 0.09654
PGS R2 (no covariates): 0.09575 [0.09152, 0.09997]		 age, sex, UKB array type, Genotype PCs —
PPM007594 PGS000954
(GBE_INI4104)
 PSS007286|
African Ancestry|
3,560 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry (L) — — R²: 0.02571 [0.01811, 0.0333]
Incremental R2 (full-covars): 0.00528
PGS R2 (no covariates): 0.00688 [0.00288, 0.01088]		 age, sex, UKB array type, Genotype PCs —
PPM007595 PGS000954
(GBE_INI4104)
 PSS007287|
East Asian Ancestry|
781 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry (L) — — R²: 0.10298 [0.0757, 0.13026]
Incremental R2 (full-covars): 0.08296
PGS R2 (no covariates): 0.082 [0.05708, 0.10691]		 age, sex, UKB array type, Genotype PCs —
PPM007596 PGS000954
(GBE_INI4104)
 PSS007288|
European Ancestry|
10,636 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry (L) — — R²: 0.17491 [0.16634, 0.18348]
Incremental R2 (full-covars): 0.11202
PGS R2 (no covariates): 0.11274 [0.10534, 0.12014]		 age, sex, UKB array type, Genotype PCs —
PPM007597 PGS000954
(GBE_INI4104)
 PSS007289|
South Asian Ancestry|
5,043 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry (L) — — R²: 0.08121 [0.06962, 0.0928]
Incremental R2 (full-covars): 0.05294
PGS R2 (no covariates): 0.05414 [0.0444, 0.06389]		 age, sex, UKB array type, Genotype PCs —
PPM007598 PGS000954
(GBE_INI4104)
 PSS007290|
European Ancestry|
25,716 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry (L) — — R²: 0.17984 [0.17459, 0.18509]
Incremental R2 (full-covars): 0.11708
PGS R2 (no covariates): 0.11589 [0.11135, 0.12043]		 age, sex, UKB array type, Genotype PCs —
PPM007599 PGS000955
(GBE_INI4120)
 PSS007306|
African Ancestry|
3,591 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel broadband ultrasound attenuation (R) — — R²: 0.03102 [0.02273, 0.03932]
Incremental R2 (full-covars): 0.0053
PGS R2 (no covariates): 0.00612 [0.00234, 0.0099]		 age, sex, UKB array type, Genotype PCs —
PPM007600 PGS000955
(GBE_INI4120)
 PSS007307|
East Asian Ancestry|
782 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel broadband ultrasound attenuation (R) — — R²: 0.1074 [0.07968, 0.13512]
Incremental R2 (full-covars): 0.06527
PGS R2 (no covariates): 0.06337 [0.04102, 0.08571]		 age, sex, UKB array type, Genotype PCs —
PPM007601 PGS000955
(GBE_INI4120)
 PSS007308|
European Ancestry|
10,633 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel broadband ultrasound attenuation (R) — — R²: 0.18118 [0.17253, 0.18984]
Incremental R2 (full-covars): 0.09282
PGS R2 (no covariates): 0.09341 [0.08653, 0.10029]		 age, sex, UKB array type, Genotype PCs —
PPM007602 PGS000955
(GBE_INI4120)
 PSS007309|
South Asian Ancestry|
5,040 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel broadband ultrasound attenuation (R) — — R²: 0.08322 [0.07151, 0.09493]
Incremental R2 (full-covars): 0.05145
PGS R2 (no covariates): 0.05095 [0.04147, 0.06044]		 age, sex, UKB array type, Genotype PCs —
PPM007603 PGS000955
(GBE_INI4120)
 PSS007310|
European Ancestry|
25,727 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel broadband ultrasound attenuation (R) — — R²: 0.20708 [0.20164, 0.21253]
Incremental R2 (full-covars): 0.10115
PGS R2 (no covariates): 0.10011 [0.09582, 0.10441]		 age, sex, UKB array type, Genotype PCs —
PPM007604 PGS000956
(GBE_INI4123)
 PSS007316|
African Ancestry|
3,592 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry (R) — — R²: 0.02463 [0.01719, 0.03208]
Incremental R2 (full-covars): 0.00617
PGS R2 (no covariates): 0.00698 [0.00295, 0.01101]		 age, sex, UKB array type, Genotype PCs —
PPM007605 PGS000956
(GBE_INI4123)
 PSS007317|
East Asian Ancestry|
782 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry (R) — — R²: 0.09886 [0.07201, 0.12571]
Incremental R2 (full-covars): 0.07542
PGS R2 (no covariates): 0.07555 [0.05147, 0.09963]		 age, sex, UKB array type, Genotype PCs —
PPM007606 PGS000956
(GBE_INI4123)
 PSS007318|
European Ancestry|
10,633 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry (R) — — R²: 0.17521 [0.16663, 0.18378]
Incremental R2 (full-covars): 0.11145
PGS R2 (no covariates): 0.11271 [0.10531, 0.12011]		 age, sex, UKB array type, Genotype PCs —
PPM007607 PGS000956
(GBE_INI4123)
 PSS007319|
South Asian Ancestry|
5,041 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry (R) — — R²: 0.08263 [0.07095, 0.0943]
Incremental R2 (full-covars): 0.05817
PGS R2 (no covariates): 0.05816 [0.0481, 0.06821]		 age, sex, UKB array type, Genotype PCs —
PPM007608 PGS000956
(GBE_INI4123)
 PSS007320|
European Ancestry|
25,728 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry (R) — — R²: 0.19359 [0.18823, 0.19894]
Incremental R2 (full-covars): 0.1242
PGS R2 (no covariates): 0.12266 [0.11802, 0.1273]		 age, sex, UKB array type, Genotype PCs —
PPM017464 PGS003536
(cont-decay-log_heel_BUA)
 PSS010900|
European Ancestry|
11,353 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — partial-R2: 0.17 sex, age, deprivation index, PC1-16 —
PPM017548 PGS003536
(cont-decay-log_heel_BUA)
 PSS010816|
European Ancestry|
2,146 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — partial-R2: 0.17 sex, age, deprivation index, PC1-16 —
PPM017632 PGS003536
(cont-decay-log_heel_BUA)
 PSS010648|
European Ancestry|
3,386 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — partial-R2: 0.13 sex, age, deprivation index, PC1-16 —
PPM017716 PGS003536
(cont-decay-log_heel_BUA)
 PSS010564|
Greater Middle Eastern Ancestry|
486 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — partial-R2: 0.1 sex, age, deprivation index, PC1-16 —
PPM017968 PGS003536
(cont-decay-log_heel_BUA)
 PSS010396|
East Asian Ancestry|
810 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — partial-R2: 0.07 sex, age, deprivation index, PC1-16 —
PPM018136 PGS003536
(cont-decay-log_heel_BUA)
 PSS010732|
African Ancestry|
1,395 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — partial-R2: 0.02 sex, age, deprivation index, PC1-16 —
PPM017800 PGS003536
(cont-decay-log_heel_BUA)
 PSS010228|
European Ancestry|
1,382 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — partial-R2: 0.14 sex, age, deprivation index, PC1-16 —
PPM017884 PGS003536
(cont-decay-log_heel_BUA)
 PSS010480|
South Asian Ancestry|
1,961 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — partial-R2: 0.09 sex, age, deprivation index, PC1-16 —
PPM018052 PGS003536
(cont-decay-log_heel_BUA)
 PSS010312|
African Ancestry|
791 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM020528 PGS004413
(X3144.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Heel Broadband ultrasound attenuation, direct entry — — PGS R2 (no covariates): 0.27085 — —
PPM020529 PGS004414
(X3147.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry — — PGS R2 (no covariates): 0.30125 — —
PPM020532 PGS004417
(X4101.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Heel broadband ultrasound attenuation (left) — — PGS R2 (no covariates): 0.21942 — —
PPM020533 PGS004418
(X4104.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry (left) — — PGS R2 (no covariates): 0.24743 — —
PPM020537 PGS004422
(X4120.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Heel broadband ultrasound attenuation (right) — — PGS R2 (no covariates): 0.22006 — —
PPM020538 PGS004423
(X4123.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Heel quantitative ultrasound index (QUI), direct entry (right) — — PGS R2 (no covariates): 0.24814 — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS007228 — — 12,376 individuals — European non-white British ancestry UKB —
PSS007229 — — 2,312 individuals — South Asian — UKB —
PSS007230 — — 38,830 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS010396 — — 810 individuals,
35.0 % Male samples
 Mean = 51.9 years
Sd = 7.5 years		 East Asian Chinese UKB —
PSS007236 — — 2,253 individuals — African unspecified — UKB —
PSS007237 — — 795 individuals — East Asian — UKB —
PSS007238 — — 12,376 individuals — European non-white British ancestry UKB —
PSS007239 — — 2,312 individuals — South Asian — UKB —
PSS007240 — — 38,834 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS010816 — — 2,146 individuals,
39.0 % Male samples
 Mean = 54.3 years
Sd = 7.2 years		 European Polish UKB —
PSS010564 — — 486 individuals,
65.0 % Male samples
 Mean = 51.1 years
Sd = 7.6 years		 Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB —
PSS010312 — — 791 individuals,
35.0 % Male samples
 Mean = 52.2 years
Sd = 8.2 years		 African American or Afro-Caribbean Caribbean UKB —
PSS007276 — — 3,559 individuals — African unspecified — UKB —
PSS007277 — — 781 individuals — East Asian — UKB —
PSS007278 — — 10,636 individuals — European non-white British ancestry UKB —
PSS007279 — — 5,043 individuals — South Asian — UKB —
PSS007280 — — 25,716 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS007286 — — 3,560 individuals — African unspecified — UKB —
PSS007287 — — 781 individuals — East Asian — UKB —
PSS007288 — — 10,636 individuals — European non-white British ancestry UKB —
PSS007289 — — 5,043 individuals — South Asian — UKB —
PSS007290 — — 25,716 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS007306 — — 3,591 individuals — African unspecified — UKB —
PSS007307 — — 782 individuals — East Asian — UKB —
PSS007308 — — 10,633 individuals — European non-white British ancestry UKB —
PSS007309 — — 5,040 individuals — South Asian — UKB —
PSS007310 — — 25,727 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS010732 — — 1,395 individuals,
49.0 % Male samples
 Mean = 52.0 years
Sd = 8.1 years		 African unspecified Nigerian UKB —
PSS010480 — — 1,961 individuals,
56.0 % Male samples
 Mean = 52.7 years
Sd = 8.2 years		 South Asian Indian UKB —
PSS010228 — — 1,382 individuals,
47.0 % Male samples
 Mean = 57.7 years
Sd = 7.1 years		 European Ashkenazi UKB —
PSS007316 — — 3,592 individuals — African unspecified — UKB —
PSS007317 — — 782 individuals — East Asian — UKB —
PSS007318 — — 10,633 individuals — European non-white British ancestry UKB —
PSS007319 — — 5,041 individuals — South Asian — UKB —
PSS007320 — — 25,728 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS011364 — — 56,192 individuals — European — UKB —
PSS010900 — — 11,353 individuals,
46.0 % Male samples
 Mean = 56.8 years
Sd = 7.8 years		 European white British UKB —
PSS010648 — — 3,386 individuals,
46.0 % Male samples
 Mean = 54.5 years
Sd = 8.2 years		 European Italian UKB —
PSS007226 — — 2,252 individuals — African unspecified — UKB —
PSS007227 — — 795 individuals — East Asian — UKB —