Trait: creatinine measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0004518
Description
  • A creatinine measurement is a measure of the metabolite creatinine in a sample. For example, in the serum, where it can be used in assessment of kidney function.
Trait category
Other measurement
Synonyms 3 synonyms
  • creatinine levels
  • serum creatinine levels
  • serum creatinine measurement
Mapped term(s) NCIt:C61023

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution PGS Scoring File (FTP Link)
PGS000678
(snpnet.Creatinine)
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Creatinine [umol/L] creatinine measurement 21,027
-
http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000678/ScoringFiles/PGS000678.txt.gz - Check Terms/Licenses

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM001579 PGS000678
(snpnet.Creatinine)
PSS000800|
European Ancestry|
2,129 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Creatinine [umol/L] Spearman's ρ: 0.24 Age, sex
PPM001406 PGS000678
(snpnet.Creatinine)
PSS000667|
African Ancestry|
6,016 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Creatinine [umol/L] : 0.37051
Spearman's ρ: 0.146
Age, sex, PCs(1-40)
PPM001441 PGS000678
(snpnet.Creatinine)
PSS000668|
East Asian Ancestry|
1,081 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Creatinine [umol/L] : 0.44314
Spearman's ρ: 0.229
Age, sex, PCs(1-40)
PPM001476 PGS000678
(snpnet.Creatinine)
PSS000674|
European Ancestry|
23,576 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Creatinine [umol/L] : 0.3939
Spearman's ρ: 0.325
Age, sex, PCs(1-40)
PPM001511 PGS000678
(snpnet.Creatinine)
PSS000675|
South Asian Ancestry|
7,339 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Creatinine [umol/L] : 0.40587
Spearman's ρ: 0.283
Age, sex, PCs(1-40)
PPM001546 PGS000678
(snpnet.Creatinine)
PSS000676|
European Ancestry|
63,758 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Creatinine [umol/L] : 0.41565
Spearman's ρ: 0.337
Age, sex, PCs(1-40)

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000667 6,016 individuals African unspecified UKB
PSS000668 1,081 individuals East Asian UKB
PSS000800 2,129 individuals European Participants self-identifying as white MESA
PSS000674 23,576 individuals European Non-British White UKB
PSS000675 7,339 individuals South Asian UKB
PSS000676 63,758 individuals European
(British)
UKB