Trait: mean corpuscular volume

Experimental Factor Ontology (EFO) Information
Identifier EFO_0004526
Description A mean corpuscular volume is the result of calculation of the mean volume of erythrocytes in a blood sample.
Trait category
Hematological measurement
Synonyms 2 synonyms
  • MCV
  • mean cell volume
Mapped term MedDRA:10027008

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS000101
(mcv)
PGP000051 |
Xu Y et al. Cell Genom (2022)
Mean corpuscular volume mean corpuscular volume 25,001
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000101/ScoringFiles/PGS000101.txt.gz
PGS000176
(mcv)
PGP000078 |
Vuckovic D et al. Cell (2020)
Mean corpuscular volume mean corpuscular volume 685
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000176/ScoringFiles/PGS000176.txt.gz
PGS000181
(mscv)
PGP000078 |
Vuckovic D et al. Cell (2020)
Mean sphered corpuscular volume mean corpuscular volume 761
-
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000181/ScoringFiles/PGS000181.txt.gz
PGS001220
(GBE_INI30040)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Mean corpuscular volume mean corpuscular volume 17,311
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001220/ScoringFiles/PGS001220.txt.gz
PGS001990
(portability-PLR_MCV)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Mean corpuscular volume mean corpuscular volume 47,916
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001990/ScoringFiles/PGS001990.txt.gz
PGS002207
(portability-ldpred2_MCV)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Mean corpuscular volume mean corpuscular volume 564,228
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002207/ScoringFiles/PGS002207.txt.gz
PGS003561
(cont-decay-MCV)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Mean corpuscular volume mean corpuscular volume 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003561/ScoringFiles/PGS003561.txt.gz
PGS003570
(cont-decay-sphered_cell_volume)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Mean sphered cell volume mean corpuscular volume 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003570/ScoringFiles/PGS003570.txt.gz
PGS003928
(INI30040)
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Mean corpuscular volume mean corpuscular volume 21,818
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003928/ScoringFiles/PGS003928.txt.gz
PGS003949
(INI30270)
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Mean sphered cell volume mean corpuscular volume 21,558
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003949/ScoringFiles/PGS003949.txt.gz
PGS004349
(X30040.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Mean corpuscular volume mean corpuscular volume 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004349/ScoringFiles/PGS004349.txt.gz
PGS004366
(X30270.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Mean sphered cell volume mean corpuscular volume 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004366/ScoringFiles/PGS004366.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000234 PGS000101
(mcv)
PSS000166|
European Ancestry|
81,431 individuals
PGP000051 |
Xu Y et al. Cell Genom (2022)
Reported Trait: Mean corpuscular volume Pearson correlation coefficent (r): 0.5624 age, sex, 10 PCs of ancestry, lifestyle factors (diet, smoking, alcohol consumption), technical covariates (the time between venepuncture and full blood cell analysis, seasonal effects, centre of sample collection, time dependent drift of equipment, systematic differences in equipment) UKB Testing Set - these samples were held out from Score Development (regression training) but overlap with the samples used for variant selection (GWAS)
PPM000235 PGS000101
(mcv)
PSS000140|
European Ancestry|
40,080 individuals
PGP000051 |
Xu Y et al. Cell Genom (2022)
Reported Trait: Mean corpuscular volume Pearson correlation coefficent (r): 0.47754 age, sex, 10 PCs of ancestry, lifestyle factors (diet, smoking, alcohol consumption), technical covariates (the time between venepuncture and full blood cell analysis, seasonal effects, centre of sample collection, time dependent drift of equipment, systematic differences in equipment)
PPM000553 PGS000176
(mcv)
PSS000290|
European Ancestry|
2,314 individuals
PGP000078 |
Vuckovic D et al. Cell (2020)
Reported Trait: Mean corpuscular volume : 0.1665 sex, age, 10 genetic PCs
PPM000532 PGS000176
(mcv)
PSS000291|
European Ancestry|
39,260 individuals
PGP000078 |
Vuckovic D et al. Cell (2020)
Reported Trait: Mean corpuscular volume : 0.15931 sex, age, 10 genetic PCs
PPM001774 PGS000176
(mcv)
PSS000911|
Greater Middle Eastern Ancestry|
13,989 individuals
PGP000147 |
Thareja G et al. Nat Commun (2021)
|Ext.
Reported Trait: Mean corpuscular volume Pearson correlation coefficent (r): 0.23
PPM008634 PGS001220
(GBE_INI30040)
PSS006926|
African Ancestry|
6,139 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Mean corpuscular volume : 0.03909 [0.02986, 0.04833]
Incremental R2 (full-covars): 0.01317
PGS R2 (no covariates): 0.01523 [0.00932, 0.02114]
age, sex, UKB array type, Genotype PCs
PPM008635 PGS001220
(GBE_INI30040)
PSS006927|
East Asian Ancestry|
1,655 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Mean corpuscular volume : 0.09134 [0.06532, 0.11737]
Incremental R2 (full-covars): 0.03736
PGS R2 (no covariates): 0.05987 [0.03807, 0.08167]
age, sex, UKB array type, Genotype PCs
PPM008636 PGS001220
(GBE_INI30040)
PSS006928|
European Ancestry|
24,175 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Mean corpuscular volume : 0.20688 [0.19792, 0.21584]
Incremental R2 (full-covars): 0.15861
PGS R2 (no covariates): 0.17414 [0.16558, 0.1827]
age, sex, UKB array type, Genotype PCs
PPM008637 PGS001220
(GBE_INI30040)
PSS006929|
South Asian Ancestry|
7,520 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Mean corpuscular volume : 0.12834 [0.11451, 0.14216]
Incremental R2 (full-covars): 0.07837
PGS R2 (no covariates): 0.08395 [0.0722, 0.0957]
age, sex, UKB array type, Genotype PCs
PPM008638 PGS001220
(GBE_INI30040)
PSS006930|
European Ancestry|
65,638 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Mean corpuscular volume : 0.21614 [0.21064, 0.22164]
Incremental R2 (full-covars): 0.19948
PGS R2 (no covariates): 0.20189 [0.19648, 0.2073]
age, sex, UKB array type, Genotype PCs
PPM010795 PGS001990
(portability-PLR_MCV)
PSS009378|
European Ancestry|
19,423 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.4447 [0.4333, 0.4559] sex, age, birth date, deprivation index, 16 PCs
PPM010796 PGS001990
(portability-PLR_MCV)
PSS009152|
European Ancestry|
4,002 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.3969 [0.3704, 0.4228] sex, age, birth date, deprivation index, 16 PCs
PPM010797 PGS001990
(portability-PLR_MCV)
PSS008706|
European Ancestry|
6,437 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.3414 [0.3196, 0.3628] sex, age, birth date, deprivation index, 16 PCs
PPM010799 PGS001990
(portability-PLR_MCV)
PSS008258|
South Asian Ancestry|
6,078 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.2987 [0.2756, 0.3214] sex, age, birth date, deprivation index, 16 PCs
PPM010800 PGS001990
(portability-PLR_MCV)
PSS008036|
East Asian Ancestry|
1,762 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.2426 [0.1979, 0.2863] sex, age, birth date, deprivation index, 16 PCs
PPM010801 PGS001990
(portability-PLR_MCV)
PSS007822|
African Ancestry|
2,342 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.2067 [0.1674, 0.2453] sex, age, birth date, deprivation index, 16 PCs
PPM010802 PGS001990
(portability-PLR_MCV)
PSS008926|
African Ancestry|
3,711 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.1227 [0.0908, 0.1543] sex, age, birth date, deprivation index, 16 PCs
PPM010798 PGS001990
(portability-PLR_MCV)
PSS008480|
Greater Middle Eastern Ancestry|
1,153 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.2898 [0.2355, 0.3422] sex, age, birth date, deprivation index, 16 PCs
PPM012503 PGS002207
(portability-ldpred2_MCV)
PSS009378|
European Ancestry|
19,423 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.4393 [0.4279, 0.4506] sex, age, birth date, deprivation index, 16 PCs
PPM012504 PGS002207
(portability-ldpred2_MCV)
PSS009152|
European Ancestry|
4,002 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.3883 [0.3616, 0.4144] sex, age, birth date, deprivation index, 16 PCs
PPM012506 PGS002207
(portability-ldpred2_MCV)
PSS008480|
Greater Middle Eastern Ancestry|
1,153 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.2809 [0.2264, 0.3337] sex, age, birth date, deprivation index, 16 PCs
PPM012507 PGS002207
(portability-ldpred2_MCV)
PSS008258|
South Asian Ancestry|
6,078 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.2928 [0.2696, 0.3156] sex, age, birth date, deprivation index, 16 PCs
PPM012508 PGS002207
(portability-ldpred2_MCV)
PSS008036|
East Asian Ancestry|
1,762 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.2554 [0.211, 0.2988] sex, age, birth date, deprivation index, 16 PCs
PPM012509 PGS002207
(portability-ldpred2_MCV)
PSS007822|
African Ancestry|
2,342 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.2029 [0.1636, 0.2416] sex, age, birth date, deprivation index, 16 PCs
PPM012505 PGS002207
(portability-ldpred2_MCV)
PSS008706|
European Ancestry|
6,437 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.3311 [0.3091, 0.3527] sex, age, birth date, deprivation index, 16 PCs
PPM012510 PGS002207
(portability-ldpred2_MCV)
PSS008926|
African Ancestry|
3,711 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Mean corpuscular volume Partial Correlation (partial-r): 0.139 [0.1072, 0.1705] sex, age, birth date, deprivation index, 16 PCs
PPM017573 PGS003561
(cont-decay-MCV)
PSS010844|
European Ancestry|
3,991 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean corpuscular volume partial-R2: 0.16 sex, age, deprivation index, PC1-16
PPM017657 PGS003561
(cont-decay-MCV)
PSS010676|
European Ancestry|
6,278 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean corpuscular volume partial-R2: 0.12 sex, age, deprivation index, PC1-16
PPM017741 PGS003561
(cont-decay-MCV)
PSS010592|
Greater Middle Eastern Ancestry|
1,123 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean corpuscular volume partial-R2: 0.08 sex, age, deprivation index, PC1-16
PPM017825 PGS003561
(cont-decay-MCV)
PSS010256|
European Ancestry|
2,264 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean corpuscular volume partial-R2: 0.16 sex, age, deprivation index, PC1-16
PPM017909 PGS003561
(cont-decay-MCV)
PSS010508|
South Asian Ancestry|
6,026 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean corpuscular volume partial-R2: 0.09 sex, age, deprivation index, PC1-16
PPM017993 PGS003561
(cont-decay-MCV)
PSS010424|
East Asian Ancestry|
1,750 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean corpuscular volume partial-R2: 0.08 sex, age, deprivation index, PC1-16
PPM018077 PGS003561
(cont-decay-MCV)
PSS010340|
African Ancestry|
2,329 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean corpuscular volume partial-R2: 0.03 sex, age, deprivation index, PC1-16
PPM018161 PGS003561
(cont-decay-MCV)
PSS010760|
African Ancestry|
3,682 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean corpuscular volume partial-R2: 0.01 sex, age, deprivation index, PC1-16
PPM017489 PGS003561
(cont-decay-MCV)
PSS010928|
European Ancestry|
19,418 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean corpuscular volume partial-R2: 0.2 sex, age, deprivation index, PC1-16
PPM017834 PGS003570
(cont-decay-sphered_cell_volume)
PSS010266|
European Ancestry|
2,220 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean sphered cell volume partial-R2: 0.16 sex, age, deprivation index, PC1-16
PPM017498 PGS003570
(cont-decay-sphered_cell_volume)
PSS010938|
European Ancestry|
19,109 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean sphered cell volume partial-R2: 0.16 sex, age, deprivation index, PC1-16
PPM017582 PGS003570
(cont-decay-sphered_cell_volume)
PSS010854|
European Ancestry|
3,913 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean sphered cell volume partial-R2: 0.15 sex, age, deprivation index, PC1-16
PPM017750 PGS003570
(cont-decay-sphered_cell_volume)
PSS010602|
Greater Middle Eastern Ancestry|
1,096 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean sphered cell volume partial-R2: 0.12 sex, age, deprivation index, PC1-16
PPM017918 PGS003570
(cont-decay-sphered_cell_volume)
PSS010518|
South Asian Ancestry|
5,885 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean sphered cell volume partial-R2: 0.1 sex, age, deprivation index, PC1-16
PPM018002 PGS003570
(cont-decay-sphered_cell_volume)
PSS010434|
East Asian Ancestry|
1,711 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean sphered cell volume partial-R2: 0.08 sex, age, deprivation index, PC1-16
PPM018086 PGS003570
(cont-decay-sphered_cell_volume)
PSS010350|
African Ancestry|
2,280 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean sphered cell volume partial-R2: 0.04 sex, age, deprivation index, PC1-16
PPM017666 PGS003570
(cont-decay-sphered_cell_volume)
PSS010686|
European Ancestry|
6,139 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean sphered cell volume partial-R2: 0.13 sex, age, deprivation index, PC1-16
PPM018170 PGS003570
(cont-decay-sphered_cell_volume)
PSS010770|
African Ancestry|
3,573 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Mean sphered cell volume partial-R2: 0.02 sex, age, deprivation index, PC1-16
PPM018959 PGS003928
(INI30040)
PSS011136|
European Ancestry|
65,932 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean corpuscular volume : 0.21483 [0.20935, 0.22031]
PGS R2 (no covariates): 0.1996 [0.19422, 0.20499]
Incremental R2 (full-covars): 0.19669
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM018960 PGS003928
(INI30040)
PSS011109|
European Ancestry|
2,813 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean corpuscular volume : 0.21868 [0.19209, 0.24527]
PGS R2 (no covariates): 0.19629 [0.17038, 0.22221]
Incremental R2 (full-covars): 0.19227
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM018961 PGS003928
(INI30040)
PSS011113|
South Asian Ancestry|
1,433 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean corpuscular volume : 0.13118 [0.09927, 0.1631]
PGS R2 (no covariates): 0.10078 [0.07183, 0.12973]
Incremental R2 (full-covars): 0.09425
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM018962 PGS003928
(INI30040)
PSS011155|
African Ancestry|
1,157 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean corpuscular volume : 0.07522 [0.04675, 0.10368]
PGS R2 (no covariates): 0.05806 [0.03259, 0.08353]
Incremental R2 (full-covars): 0.05248
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM018963 PGS003928
(INI30040)
PSS011166|
Multi-ancestry (excluding European)|
7,746 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean corpuscular volume : 0.18827 [0.17284, 0.20369]
PGS R2 (no covariates): 0.14096 [0.12683, 0.15508]
Incremental R2 (full-covars): 0.11206
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM019064 PGS003949
(INI30270)
PSS011143|
European Ancestry|
64,816 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean sphered cell volume : 0.16403 [0.15893, 0.16913]
PGS R2 (no covariates): 0.15331 [0.14832, 0.15831]
Incremental R2 (full-covars): 0.15179
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM019065 PGS003949
(INI30270)
PSS011100|
European Ancestry|
2,768 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean sphered cell volume : 0.17891 [0.15363, 0.20418]
PGS R2 (no covariates): 0.15547 [0.13123, 0.1797]
Incremental R2 (full-covars): 0.15478
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM019066 PGS003949
(INI30270)
PSS011111|
South Asian Ancestry|
1,393 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean sphered cell volume : 0.11613 [0.08558, 0.14667]
PGS R2 (no covariates): 0.10275 [0.07358, 0.13192]
Incremental R2 (full-covars): 0.09928
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM019067 PGS003949
(INI30270)
PSS011153|
African Ancestry|
1,125 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean sphered cell volume : 0.03373 [0.01382, 0.05365]
PGS R2 (no covariates): 0.03281 [0.01315, 0.05248]
Incremental R2 (full-covars): 0.03191
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM019068 PGS003949
(INI30270)
PSS011170|
Multi-ancestry (excluding European)|
7,574 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Mean sphered cell volume : 0.16365 [0.14884, 0.17847]
PGS R2 (no covariates): 0.13716 [0.12317, 0.15116]
Incremental R2 (full-covars): 0.12494
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM020464 PGS004349
(X30040.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: Mean corpuscular volume PGS R2 (no covariates): 0.31845
PPM020481 PGS004366
(X30270.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: Mean sphered cell volume PGS R2 (no covariates): 0.27321

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS011143 64,816 individuals European
(white British ancestry)
UKB
PSS011153 1,125 individuals African unspecified UKB
PSS011155 1,157 individuals African unspecified UKB
PSS010928 19,418 individuals,
46.0 % Male samples
Mean = 56.9 years
Sd = 7.9 years
European white British UKB
PSS011136 65,932 individuals European
(white British ancestry)
UKB
PSS010676 6,278 individuals,
45.0 % Male samples
Mean = 54.5 years
Sd = 8.4 years
European Italian UKB
PSS008926 3,711 individuals African unspecified Nigeria (West Africa) UKB
PSS010424 1,750 individuals,
33.0 % Male samples
Mean = 52.5 years
Sd = 7.8 years
East Asian Chinese UKB
PSS010938 19,109 individuals,
46.0 % Male samples
Mean = 56.9 years
Sd = 7.9 years
European white British UKB
PSS011166 7,746 individuals East Asian, Other admixed ancestry East Asian, Other admixed ancestry UKB
PSS011170 7,574 individuals East Asian, Other admixed ancestry East Asian, Other admixed ancestry UKB
PSS008036 1,762 individuals East Asian China (East Asia) UKB
PSS010686 6,139 individuals,
45.0 % Male samples
Mean = 54.4 years
Sd = 8.4 years
European Italian UKB
PSS010434 1,711 individuals,
33.0 % Male samples
Mean = 52.4 years
Sd = 7.8 years
East Asian Chinese UKB
PSS000290 2,314 individuals European
(French Canadian)
CARTaGENE
PSS000291 39,260 individuals European INTERVAL
PSS000911 13,989 individuals Greater Middle Eastern (Middle Eastern, North African or Persian)
(Qatari)
QBB
PSS008706 6,437 individuals European Italy (South Europe) UKB
PSS010844 3,991 individuals,
38.0 % Male samples
Mean = 54.3 years
Sd = 7.5 years
European Polish UKB
PSS010592 1,123 individuals,
59.0 % Male samples
Mean = 52.0 years
Sd = 8.0 years
Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB
PSS010340 2,329 individuals,
36.0 % Male samples
Mean = 52.4 years
Sd = 8.0 years
African American or Afro-Caribbean Caribbean UKB
PSS000140 40,080 individuals,
50.0 % Male samples
Mean = 43.82 years
Range = [18.0, 76.4] years
European INTERVAL
PSS010854 3,913 individuals,
38.0 % Male samples
Mean = 54.3 years
Sd = 7.5 years
European Polish UKB
PSS007822 2,342 individuals African American or Afro-Caribbean Carribean UKB
PSS010602 1,096 individuals,
59.0 % Male samples
Mean = 52.0 years
Sd = 8.0 years
Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB
PSS010350 2,280 individuals,
37.0 % Male samples
Mean = 52.4 years
Sd = 8.0 years
African American or Afro-Caribbean Caribbean UKB
PSS006926 6,139 individuals African unspecified UKB
PSS006927 1,655 individuals East Asian UKB
PSS006928 24,175 individuals European non-white British ancestry UKB
PSS006929 7,520 individuals South Asian UKB
PSS006930 65,638 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS011100 2,768 individuals European
(non-white British ancestry)
UKB
PSS011364 56,192 individuals European UKB
PSS008480 1,153 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009378 19,423 individuals European UK (+ Ireland) UKB
PSS011109 2,813 individuals European
(non-white British ancestry)
UKB
PSS000166 81,431 individuals,
46.0 % Male samples
Mean = 57.26 years
Range = [40.15, 71.1] years
European UKB
PSS011111 1,393 individuals South Asian UKB
PSS011113 1,433 individuals South Asian UKB
PSS010760 3,682 individuals,
47.0 % Male samples
Mean = 51.9 years
Sd = 8.1 years
African unspecified Nigerian UKB
PSS010508 6,026 individuals,
55.0 % Male samples
Mean = 53.3 years
Sd = 8.4 years
South Asian Indian UKB
PSS010266 2,220 individuals,
45.0 % Male samples
Mean = 58.0 years
Sd = 7.1 years
European Ashkenazi UKB
PSS010256 2,264 individuals,
45.0 % Male samples
Mean = 58.0 years
Sd = 7.1 years
European Ashkenazi UKB
PSS010770 3,573 individuals,
47.0 % Male samples
Mean = 51.9 years
Sd = 8.1 years
African unspecified Nigerian UKB
PSS010518 5,885 individuals,
55.0 % Male samples
Mean = 53.3 years
Sd = 8.4 years
South Asian Indian UKB
PSS009152 4,002 individuals European Poland (NE Europe) UKB
PSS008258 6,078 individuals South Asian India (South Asia) UKB