Trait: serum non-albumin protein measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0004568
Description
  • The measurement of the non-albumin portion of blood protein (globulin) in serum
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution PGS Scoring File (FTP Link)
PGS000691
(snpnet.Non_albumin_protein)
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Non-albumin protein [g/L] serum non-albumin protein measurement 18,670
-
http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000691/ScoringFiles/PGS000691.txt.gz - Check Terms/Licenses

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM001559 PGS000691
(snpnet.Non_albumin_protein)
PSS000733|
European Ancestry|
58,196 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Non-albumin protein [g/L] : 0.12321
Spearman's ρ: 0.311
Age, sex, PCs(1-40)
PPM001524 PGS000691
(snpnet.Non_albumin_protein)
PSS000732|
South Asian Ancestry|
6,687 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Non-albumin protein [g/L] : 0.15158
Spearman's ρ: 0.292
Age, sex, PCs(1-40)
PPM001489 PGS000691
(snpnet.Non_albumin_protein)
PSS000731|
European Ancestry|
21,516 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Non-albumin protein [g/L] : 0.12839
Spearman's ρ: 0.31
Age, sex, PCs(1-40)
PPM001454 PGS000691
(snpnet.Non_albumin_protein)
PSS000730|
East Asian Ancestry|
984 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Non-albumin protein [g/L] : 0.0886
Spearman's ρ: 0.216
Age, sex, PCs(1-40)
PPM001419 PGS000691
(snpnet.Non_albumin_protein)
PSS000729|
African Ancestry|
5,573 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Non-albumin protein [g/L] : 0.07146
Spearman's ρ: 0.16
Age, sex, PCs(1-40)

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000729 5,573 individuals African unspecified UKB
PSS000730 984 individuals East Asian UKB
PSS000731 21,516 individuals European Non-British White UKB
PSS000732 6,687 individuals South Asian UKB
PSS000733 58,196 individuals European
(British)
UKB