Trait: fat body mass

Experimental Factor Ontology (EFO) Information
Identifier EFO_0005409
Description The weight of the individual's body fat.
Trait category
Other measurement
Synonym total body fat measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS001144
(GBE_INI23124)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Arm fat mass (L) fat body mass 23,676
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001144/ScoringFiles/PGS001144.txt.gz
PGS001145
(GBE_INI23120)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Arm fat mass (R) fat body mass 23,528
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001145/ScoringFiles/PGS001145.txt.gz
PGS001146
(GBE_INI23121)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Arm fat-free mass (R) fat body mass 29,063
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001146/ScoringFiles/PGS001146.txt.gz
PGS001147
(GBE_INI23112)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Leg fat mass (R) fat body mass 23,565
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001147/ScoringFiles/PGS001147.txt.gz
PGS001148
(GBE_INI23128)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Trunk fat mass fat body mass 29,233
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001148/ScoringFiles/PGS001148.txt.gz
PGS001149
(GBE_INI23100)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Whole body fat mass fat body mass 27,550
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001149/ScoringFiles/PGS001149.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM008447 PGS001144
(GBE_INI23124)
PSS005146|
African Ancestry|
6,301 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat mass (L) : 0.19829 [0.18093, 0.21564]
Incremental R2 (full-covars): 0.01056
PGS R2 (no covariates): 0.0115 [0.00635, 0.01665]
age, sex, UKB array type, Genotype PCs
PPM008448 PGS001144
(GBE_INI23124)
PSS005147|
East Asian Ancestry|
1,678 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat mass (L) : 0.10217 [0.07498, 0.12937]
Incremental R2 (full-covars): 0.01559
PGS R2 (no covariates): 0.04382 [0.02485, 0.06278]
age, sex, UKB array type, Genotype PCs
PPM008449 PGS001144
(GBE_INI23124)
PSS005148|
European Ancestry|
24,458 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat mass (L) : 0.11004 [0.10271, 0.11737]
Incremental R2 (full-covars): 0.07159
PGS R2 (no covariates): 0.07386 [0.06761, 0.08012]
age, sex, UKB array type, Genotype PCs
PPM008450 PGS001144
(GBE_INI23124)
PSS005149|
South Asian Ancestry|
7,647 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat mass (L) : 0.16359 [0.14861, 0.17857]
Incremental R2 (full-covars): 0.04415
PGS R2 (no covariates): 0.04982 [0.04043, 0.05921]
age, sex, UKB array type, Genotype PCs
PPM008451 PGS001144
(GBE_INI23124)
PSS005150|
European Ancestry|
66,237 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat mass (L) : 0.1322 [0.12743, 0.13696]
Incremental R2 (full-covars): 0.07627
PGS R2 (no covariates): 0.07725 [0.07338, 0.08112]
age, sex, UKB array type, Genotype PCs
PPM008452 PGS001145
(GBE_INI23120)
PSS005126|
African Ancestry|
6,302 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat mass (R) : 0.20498 [0.18748, 0.22247]
Incremental R2 (full-covars): 0.0099
PGS R2 (no covariates): 0.01125 [0.00615, 0.01635]
age, sex, UKB array type, Genotype PCs
PPM008453 PGS001145
(GBE_INI23120)
PSS005127|
East Asian Ancestry|
1,678 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat mass (R) : 0.1096 [0.08166, 0.13753]
Incremental R2 (full-covars): 0.02033
PGS R2 (no covariates): 0.04736 [0.02771, 0.06701]
age, sex, UKB array type, Genotype PCs
PPM008454 PGS001145
(GBE_INI23120)
PSS005128|
European Ancestry|
24,456 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat mass (R) : 0.11299 [0.10558, 0.12039]
Incremental R2 (full-covars): 0.07263
PGS R2 (no covariates): 0.07483 [0.06855, 0.08112]
age, sex, UKB array type, Genotype PCs
PPM008455 PGS001145
(GBE_INI23120)
PSS005129|
South Asian Ancestry|
7,649 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat mass (R) : 0.1687 [0.15358, 0.18381]
Incremental R2 (full-covars): 0.04455
PGS R2 (no covariates): 0.04978 [0.04039, 0.05916]
age, sex, UKB array type, Genotype PCs
PPM008456 PGS001145
(GBE_INI23120)
PSS005130|
European Ancestry|
66,249 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat mass (R) : 0.13668 [0.13186, 0.1415]
Incremental R2 (full-covars): 0.07881
PGS R2 (no covariates): 0.07963 [0.07571, 0.08355]
age, sex, UKB array type, Genotype PCs
PPM008459 PGS001146
(GBE_INI23121)
PSS005133|
European Ancestry|
24,458 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat-free mass (R) : 0.76277 [0.75762, 0.76791]
Incremental R2 (full-covars): 0.03623
PGS R2 (no covariates): 0.03786 [0.03321, 0.04251]
age, sex, UKB array type, Genotype PCs
PPM008457 PGS001146
(GBE_INI23121)
PSS005131|
African Ancestry|
6,302 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat-free mass (R) : 0.64816 [0.63439, 0.66193]
Incremental R2 (full-covars): 0.00971
PGS R2 (no covariates): 0.01621 [0.01012, 0.02229]
age, sex, UKB array type, Genotype PCs
PPM008458 PGS001146
(GBE_INI23121)
PSS005132|
East Asian Ancestry|
1,678 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat-free mass (R) : 0.75781 [0.73783, 0.77779]
Incremental R2 (full-covars): 0.0021
PGS R2 (no covariates): 0.01403 [0.00296, 0.0251]
age, sex, UKB array type, Genotype PCs
PPM008460 PGS001146
(GBE_INI23121)
PSS005134|
South Asian Ancestry|
7,649 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat-free mass (R) : 0.70823 [0.69735, 0.7191]
Incremental R2 (full-covars): 0.02714
PGS R2 (no covariates): 0.018 [0.01216, 0.02383]
age, sex, UKB array type, Genotype PCs
PPM008461 PGS001146
(GBE_INI23121)
PSS005135|
European Ancestry|
66,249 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Arm fat-free mass (R) : 0.75647 [0.75327, 0.75966]
Incremental R2 (full-covars): 0.0401
PGS R2 (no covariates): 0.04083 [0.03791, 0.04376]
age, sex, UKB array type, Genotype PCs
PPM008462 PGS001147
(GBE_INI23112)
PSS005091|
African Ancestry|
6,305 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leg fat mass (R) : 0.43888 [0.42081, 0.45695]
Incremental R2 (full-covars): 0.00478
PGS R2 (no covariates): 0.00647 [0.00258, 0.01035]
age, sex, UKB array type, Genotype PCs
PPM008463 PGS001147
(GBE_INI23112)
PSS005092|
East Asian Ancestry|
1,680 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leg fat mass (R) : 0.46789 [0.43339, 0.50238]
Incremental R2 (full-covars): -0.00071
PGS R2 (no covariates): 0.03169 [0.01535, 0.04803]
age, sex, UKB array type, Genotype PCs
PPM008464 PGS001147
(GBE_INI23112)
PSS005093|
European Ancestry|
24,463 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leg fat mass (R) : 0.34025 [0.33069, 0.34981]
Incremental R2 (full-covars): 0.05666
PGS R2 (no covariates): 0.05548 [0.04995, 0.061]
age, sex, UKB array type, Genotype PCs
PPM008465 PGS001147
(GBE_INI23112)
PSS005094|
South Asian Ancestry|
7,649 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leg fat mass (R) : 0.44907 [0.43273, 0.46542]
Incremental R2 (full-covars): 0.02496
PGS R2 (no covariates): 0.03286 [0.0251, 0.04063]
age, sex, UKB array type, Genotype PCs
PPM008466 PGS001147
(GBE_INI23112)
PSS005095|
European Ancestry|
66,259 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leg fat mass (R) : 0.37892 [0.37315, 0.38469]
Incremental R2 (full-covars): 0.06155
PGS R2 (no covariates): 0.0616 [0.05808, 0.06511]
age, sex, UKB array type, Genotype PCs
PPM008467 PGS001148
(GBE_INI23128)
PSS005166|
African Ancestry|
6,299 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Trunk fat mass : 0.07784 [0.06534, 0.09035]
Incremental R2 (full-covars): 0.00763
PGS R2 (no covariates): 0.01681 [0.01061, 0.023]
age, sex, UKB array type, Genotype PCs
PPM008468 PGS001148
(GBE_INI23128)
PSS005167|
East Asian Ancestry|
1,678 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Trunk fat mass : 0.08471 [0.05946, 0.10995]
Incremental R2 (full-covars): 0.02256
PGS R2 (no covariates): 0.04289 [0.0241, 0.06167]
age, sex, UKB array type, Genotype PCs
PPM008469 PGS001148
(GBE_INI23128)
PSS005168|
European Ancestry|
24,450 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Trunk fat mass : 0.12525 [0.11756, 0.13293]
Incremental R2 (full-covars): 0.09644
PGS R2 (no covariates): 0.10468 [0.09748, 0.11187]
age, sex, UKB array type, Genotype PCs
PPM008470 PGS001148
(GBE_INI23128)
PSS005169|
South Asian Ancestry|
7,646 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Trunk fat mass : 0.08664 [0.07474, 0.09855]
Incremental R2 (full-covars): 0.06072
PGS R2 (no covariates): 0.06279 [0.05239, 0.07318]
age, sex, UKB array type, Genotype PCs
PPM008471 PGS001148
(GBE_INI23128)
PSS005170|
European Ancestry|
66,220 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Trunk fat mass : 0.11749 [0.11293, 0.12206]
Incremental R2 (full-covars): 0.1078
PGS R2 (no covariates): 0.10871 [0.10428, 0.11315]
age, sex, UKB array type, Genotype PCs
PPM008472 PGS001149
(GBE_INI23100)
PSS005041|
African Ancestry|
6,294 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Whole body fat mass : 0.22098 [0.20318, 0.23878]
Incremental R2 (full-covars): 0.00715
PGS R2 (no covariates): 0.01342 [0.00786, 0.01897]
age, sex, UKB array type, Genotype PCs
PPM008473 PGS001149
(GBE_INI23100)
PSS005042|
East Asian Ancestry|
1,667 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Whole body fat mass : 0.10565 [0.0781, 0.1332]
Incremental R2 (full-covars): 0.01419
PGS R2 (no covariates): 0.04325 [0.0244, 0.06211]
age, sex, UKB array type, Genotype PCs
PPM008474 PGS001149
(GBE_INI23100)
PSS005043|
European Ancestry|
24,422 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Whole body fat mass : 0.1432 [0.13515, 0.15125]
Incremental R2 (full-covars): 0.08949
PGS R2 (no covariates): 0.09358 [0.08669, 0.10047]
age, sex, UKB array type, Genotype PCs
PPM008475 PGS001149
(GBE_INI23100)
PSS005044|
South Asian Ancestry|
7,639 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Whole body fat mass : 0.17436 [0.1591, 0.18963]
Incremental R2 (full-covars): 0.05377
PGS R2 (no covariates): 0.06028 [0.05006, 0.07049]
age, sex, UKB array type, Genotype PCs
PPM008476 PGS001149
(GBE_INI23100)
PSS005045|
European Ancestry|
66,165 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Whole body fat mass : 0.16366 [0.15856, 0.16877]
Incremental R2 (full-covars): 0.09847
PGS R2 (no covariates): 0.09893 [0.09465, 0.10321]
age, sex, UKB array type, Genotype PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS005043 24,422 individuals European non-white British ancestry UKB
PSS005044 7,639 individuals South Asian UKB
PSS005091 6,305 individuals African unspecified UKB
PSS005092 1,680 individuals East Asian UKB
PSS005093 24,463 individuals European non-white British ancestry UKB
PSS005094 7,649 individuals South Asian UKB
PSS005095 66,259 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS005126 6,302 individuals African unspecified UKB
PSS005127 1,678 individuals East Asian UKB
PSS005128 24,456 individuals European non-white British ancestry UKB
PSS005129 7,649 individuals South Asian UKB
PSS005130 66,249 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS005131 6,302 individuals African unspecified UKB
PSS005132 1,678 individuals East Asian UKB
PSS005133 24,458 individuals European non-white British ancestry UKB
PSS005134 7,649 individuals South Asian UKB
PSS005135 66,249 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS005146 6,301 individuals African unspecified UKB
PSS005147 1,678 individuals East Asian UKB
PSS005148 24,458 individuals European non-white British ancestry UKB
PSS005149 7,647 individuals South Asian UKB
PSS005150 66,237 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS005166 6,299 individuals African unspecified UKB
PSS005167 1,678 individuals East Asian UKB
PSS005168 24,450 individuals European non-white British ancestry UKB
PSS005169 7,646 individuals South Asian UKB
PSS005170 66,220 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS005041 6,294 individuals African unspecified UKB
PSS005042 1,667 individuals East Asian UKB
PSS005045 66,165 individuals European white British ancestry UKB Testing cohort (heldout set)