Trait: velocity of sound measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0005654
Description quantification of the speed at which sound travels through bone as an indicator of the physical and structural properties of the bone
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS001957
(portability-PLR_log_heel_SoS)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Speed of sound through heel velocity of sound measurement 65,064
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001957/ScoringFiles/PGS001957.txt.gz
PGS002175
(portability-ldpred2_log_heel_SoS)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Speed of sound through heel velocity of sound measurement 724,667
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002175/ScoringFiles/PGS002175.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010531 PGS001957
(portability-PLR_log_heel_SoS)
PSS009448|
European Ancestry|
11,504 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.4182 [0.403, 0.4332] sex, age, birth date, deprivation index, 16 PCs
PPM010532 PGS001957
(portability-PLR_log_heel_SoS)
PSS009222|
European Ancestry|
2,149 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.403 [0.3668, 0.438] sex, age, birth date, deprivation index, 16 PCs
PPM010533 PGS001957
(portability-PLR_log_heel_SoS)
PSS008776|
European Ancestry|
3,470 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.3476 [0.3179, 0.3766] sex, age, birth date, deprivation index, 16 PCs
PPM010534 PGS001957
(portability-PLR_log_heel_SoS)
PSS008550|
Greater Middle Eastern Ancestry|
507 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.2669 [0.1823, 0.3475] sex, age, birth date, deprivation index, 16 PCs
PPM010535 PGS001957
(portability-PLR_log_heel_SoS)
PSS008328|
South Asian Ancestry|
1,986 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.3007 [0.26, 0.3404] sex, age, birth date, deprivation index, 16 PCs
PPM010536 PGS001957
(portability-PLR_log_heel_SoS)
PSS008105|
East Asian Ancestry|
820 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.2977 [0.2332, 0.3596] sex, age, birth date, deprivation index, 16 PCs
PPM010537 PGS001957
(portability-PLR_log_heel_SoS)
PSS007892|
African Ancestry|
801 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.1697 [0.1008, 0.237] sex, age, birth date, deprivation index, 16 PCs
PPM010538 PGS001957
(portability-PLR_log_heel_SoS)
PSS008996|
African Ancestry|
1,421 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.1551 [0.1035, 0.2058] sex, age, birth date, deprivation index, 16 PCs
PPM012247 PGS002175
(portability-ldpred2_log_heel_SoS)
PSS009448|
European Ancestry|
11,504 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.41 [0.3947, 0.4251] sex, age, birth date, deprivation index, 16 PCs
PPM012248 PGS002175
(portability-ldpred2_log_heel_SoS)
PSS009222|
European Ancestry|
2,149 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.3934 [0.3568, 0.4287] sex, age, birth date, deprivation index, 16 PCs
PPM012249 PGS002175
(portability-ldpred2_log_heel_SoS)
PSS008776|
European Ancestry|
3,470 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.3448 [0.315, 0.3738] sex, age, birth date, deprivation index, 16 PCs
PPM012250 PGS002175
(portability-ldpred2_log_heel_SoS)
PSS008550|
Greater Middle Eastern Ancestry|
507 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.2733 [0.1891, 0.3536] sex, age, birth date, deprivation index, 16 PCs
PPM012251 PGS002175
(portability-ldpred2_log_heel_SoS)
PSS008328|
South Asian Ancestry|
1,986 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.2963 [0.2554, 0.3361] sex, age, birth date, deprivation index, 16 PCs
PPM012252 PGS002175
(portability-ldpred2_log_heel_SoS)
PSS008105|
East Asian Ancestry|
820 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.2873 [0.2224, 0.3496] sex, age, birth date, deprivation index, 16 PCs
PPM012253 PGS002175
(portability-ldpred2_log_heel_SoS)
PSS007892|
African Ancestry|
801 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.1599 [0.0908, 0.2275] sex, age, birth date, deprivation index, 16 PCs
PPM012254 PGS002175
(portability-ldpred2_log_heel_SoS)
PSS008996|
African Ancestry|
1,421 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Speed of sound through heel Partial Correlation (partial-r): 0.1518 [0.1003, 0.2026] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008996 1,421 individuals African unspecified Nigeria (West Africa) UKB
PSS008550 507 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009222 2,149 individuals European Poland (NE Europe) UKB
PSS008776 3,470 individuals European Italy (South Europe) UKB
PSS008328 1,986 individuals South Asian India (South Asia) UKB
PSS009448 11,504 individuals European UK (+ Ireland) UKB
PSS008105 820 individuals East Asian China (East Asia) UKB
PSS007892 801 individuals African American or Afro-Caribbean Carribean UKB