Trait: depressive episode measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0007704
Description quantification of some aspect, eg frequency or severity, of depressive episodes in patients with mental or behavioural disorders such as bipolar disorder or clinical depression
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS002113
(portability-ldpred2_depression_stress_trauma)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Depression possibly related to stressful or traumatic event depressive episode measurement,
trauma exposure measurement
545,334
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002113/ScoringFiles/PGS002113.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM011760 PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS009170|
European Ancestry|
741 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic event Partial Correlation (partial-r): 0.0272 [-0.0459, 0.1001] sex, age, birth date, deprivation index, 16 PCs
PPM011759 PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS009396|
European Ancestry|
3,597 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic event Partial Correlation (partial-r): 0.0378 [0.005, 0.0705] sex, age, birth date, deprivation index, 16 PCs
PPM011761 PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS008724|
European Ancestry|
1,364 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic event Partial Correlation (partial-r): 0.0391 [-0.0144, 0.0924] sex, age, birth date, deprivation index, 16 PCs
PPM011762 PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS008498|
Greater Middle Eastern Ancestry|
100 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic event Partial Correlation (partial-r): -0.0739 [-0.2889, 0.1482] sex, age, birth date, deprivation index, 16 PCs
PPM011763 PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS008276|
South Asian Ancestry|
425 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic event Partial Correlation (partial-r): 0.1438 [0.0471, 0.238] sex, age, birth date, deprivation index, 16 PCs
PPM011764 PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS008053|
East Asian Ancestry|
215 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic event Partial Correlation (partial-r): 0.0141 [-0.1267, 0.1543] sex, age, birth date, deprivation index, 16 PCs
PPM011765 PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS007840|
African Ancestry|
215 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic event Partial Correlation (partial-r): -0.0269 [-0.1668, 0.114] sex, age, birth date, deprivation index, 16 PCs
PPM011766 PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS008944|
African Ancestry|
214 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic event Partial Correlation (partial-r): -0.0334 [-0.1734, 0.108] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008944 214 individuals African unspecified Nigeria (West Africa) UKB
PSS008498 100 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009170 741 individuals European Poland (NE Europe) UKB
PSS009396 3,597 individuals European UK (+ Ireland) UKB
PSS008724 1,364 individuals European Italy (South Europe) UKB
PSS008276 425 individuals South Asian India (South Asia) UKB
PSS008053 215 individuals East Asian China (East Asia) UKB
PSS007840 215 individuals African American or Afro-Caribbean Carribean UKB