Trait: risk-taking behaviour

Experimental Factor Ontology (EFO) Information
Identifier EFO_0008579
Description
  • The tendency to take risks. Risk-taking behaviour is a characteristic of several psychiatric disorders such as ADHD and bipolar disorder, as well as problem behaviours such as smoking and drug abuse.
Trait category
Biological process

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution PGS Scoring File (FTP Link)
PGS000205
(RISK_PC_COGA)
PGP000084 |
Barr PB et al. Transl Psychiatry (2020)
Risk-taking tendency (4-domain principal component model) risk-taking behaviour 1,110,737
-
http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000205/ScoringFiles/PGS000205.txt.gz
PGS000206
(RISK_PC_FT12)
PGP000084 |
Barr PB et al. Transl Psychiatry (2020)
Risk-taking tendency (4-domain principal component model) risk-taking behaviour 1,098,765
-
http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000206/ScoringFiles/PGS000206.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000630 PGS000206
(RISK_PC_FT12)
PSS000340|
European Ancestry|
1,251 individuals
PGP000084 |
Barr PB et al. Transl Psychiatry (2020)
Reported Trait: Alcohol use disorder (DSM-5 criteria count, log-transformed) β: 0.1 (0.02) ΔR-squared (vs. covariates alone): 0.02273 sex, age of last observation, 10 Genetic PCs
PPM000627 PGS000205
(RISK_PC_COGA)
PSS000339|
European Ancestry|
7,599 individuals
PGP000084 |
Barr PB et al. Transl Psychiatry (2020)
Reported Trait: Alcohol use disorder (DSM-5 criteria count, log-transformed) β: 0.117 (0.011) ΔR-squared (vs. covariates alone): 0.01613 sex, age of last observation, 10 Genetic PCs, genotyping array, data collection site

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000340 1,251 individuals,
45.6 % Male samples
Mean = 21.9 years
Sd = 0.77 years
Range = [21.0, 26.0] years
European
(Finnish)
FinnTwin12 Twin Study
PSS000339 7,599 individuals,
47.16 % Male samples
Mean = 36.94 years
Sd = 14.77 years
Range = [12.0, 91.0] years
European COGA