Trait: fall

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009631
Description A sudden movement downward, usually resulting in injury. [ NCI ]
Trait category
Other trait
Mapped terms 2 mapped terms
  • ICD10:W19
  • NCIt:C50558

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS001012
(GBE_QT_FC1002296)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Number of falls in the last year fall 2,103
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001012/ScoringFiles/PGS001012.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007823 PGS001012
(GBE_QT_FC1002296)
PSS007596|
African Ancestry|
6,336 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Falls in the last year Incremental R2 (full-covars): -0.00094
: 0.01681 [0.01062, 0.02301]
PGS R2 (no covariates): 3e-05 [-0.00022, 0.00027]
age, sex, UKB array type, Genotype PCs
PPM007824 PGS001012
(GBE_QT_FC1002296)
PSS007597|
East Asian Ancestry|
1,629 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Falls in the last year : 0.0157 [0.00401, 0.02739]
Incremental R2 (full-covars): -0.00264
PGS R2 (no covariates): 0.00011 [-0.00088, 0.00109]
age, sex, UKB array type, Genotype PCs
PPM007825 PGS001012
(GBE_QT_FC1002296)
PSS007598|
European Ancestry|
24,790 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Falls in the last year : 0.0119 [0.00923, 0.01458]
Incremental R2 (full-covars): 0.00165
PGS R2 (no covariates): 0.00166 [0.00065, 0.00267]
age, sex, UKB array type, Genotype PCs
PPM007826 PGS001012
(GBE_QT_FC1002296)
PSS007599|
South Asian Ancestry|
7,443 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Falls in the last year : 0.01243 [0.00756, 0.01731]
Incremental R2 (full-covars): -0.00079
PGS R2 (no covariates): 0.00021 [-0.00043, 0.00084]
age, sex, UKB array type, Genotype PCs
PPM007827 PGS001012
(GBE_QT_FC1002296)
PSS007600|
European Ancestry|
67,306 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Falls in the last year : 0.01122 [0.00964, 0.0128]
Incremental R2 (full-covars): 0.00106
PGS R2 (no covariates): 0.00126 [0.00073, 0.0018]
age, sex, UKB array type, Genotype PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS007596 6,336 individuals African unspecified UKB
PSS007597 1,629 individuals East Asian UKB
PSS007598 24,790 individuals European non-white British ancestry UKB
PSS007599 7,443 individuals South Asian UKB
PSS007600 67,306 individuals European white British ancestry UKB Testing cohort (heldout set)