Trait: father's age at death

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009712
Description The age of a person's father at which father's death occurred.
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001393
(GBE_INI1807)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Father's age at death father's age at death 398
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001393/ScoringFiles/PGS001393.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM005245 PGS001393
(GBE_INI1807)
 PSS004881|
African Ancestry|
3,727 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Father's age at death — — R²: 0.0481 [0.03795, 0.05825]
Incremental R2 (full-covars): 4e-05
PGS R2 (no covariates): 1e-05 [-0.00012, 0.00013]		 age, sex, UKB array type, Genotype PCs —
PPM005246 PGS001393
(GBE_INI1807)
 PSS004882|
East Asian Ancestry|
1,064 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Father's age at death — — R²: 0.03491 [0.01782, 0.052]
Incremental R2 (full-covars): 0.00101
PGS R2 (no covariates): 0.0017 [-0.0022, 0.00561]		 age, sex, UKB array type, Genotype PCs —
PPM005247 PGS001393
(GBE_INI1807)
 PSS004883|
European Ancestry|
18,430 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Father's age at death — — R²: 0.01726 [0.01405, 0.02046]
Incremental R2 (full-covars): 0.00081
PGS R2 (no covariates): 0.0009 [0.00016, 0.00165]		 age, sex, UKB array type, Genotype PCs —
PPM005248 PGS001393
(GBE_INI1807)
 PSS004884|
South Asian Ancestry|
5,395 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Father's age at death — — R²: 0.03831 [0.02998, 0.04664]
Incremental R2 (full-covars): -0.00045
PGS R2 (no covariates): 0.0 [-0.00003, 0.00003]		 age, sex, UKB array type, Genotype PCs —
PPM005249 PGS001393
(GBE_INI1807)
 PSS004885|
European Ancestry|
50,953 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Father's age at death — — R²: 0.01864 [0.01661, 0.02066]
Incremental R2 (full-covars): 0.0006
PGS R2 (no covariates): 0.00069 [0.00029, 0.00108]		 age, sex, UKB array type, Genotype PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS004881 — — 3,727 individuals — African unspecified — UKB —
PSS004882 — — 1,064 individuals — East Asian — UKB —
PSS004883 — — 18,430 individuals — European non-white British ancestry UKB —
PSS004884 — — 5,395 individuals — South Asian — UKB —
PSS004885 — — 50,953 individuals — European white British ancestry UKB Testing cohort (heldout set)