Trait: serum urea measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009795
Description
  • Quantification of the amount of urea in serum.
Trait category
Other measurement
Synonyms urea measurement
Mapped term(s) PMID:30808845

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution PGS Scoring File (FTP Link)
PGS000701
(snpnet.Urea)
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Urea [mmol/L] serum urea measurement 12,351
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http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000701/ScoringFiles/PGS000701.txt.gz - Check Terms/Licenses

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM001569 PGS000701
(snpnet.Urea)
PSS000786|
European Ancestry|
63,745 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Urea [mmol/L] : 0.15214
Spearman's ρ: 0.223
Age, sex, PCs(1-40)
PPM001534 PGS000701
(snpnet.Urea)
PSS000785|
South Asian Ancestry|
7,336 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Urea [mmol/L] : 0.15556
Spearman's ρ: 0.174
Age, sex, PCs(1-40)
PPM001499 PGS000701
(snpnet.Urea)
PSS000784|
European Ancestry|
23,562 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Urea [mmol/L] : 0.15772
Spearman's ρ: 0.205
Age, sex, PCs(1-40)
PPM001464 PGS000701
(snpnet.Urea)
PSS000783|
East Asian Ancestry|
1,080 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Urea [mmol/L] : 0.12883
Spearman's ρ: 0.147
Age, sex, PCs(1-40)
PPM001429 PGS000701
(snpnet.Urea)
PSS000782|
African Ancestry|
6,015 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Urea [mmol/L] : 0.13035
Spearman's ρ: 0.111
Age, sex, PCs(1-40)

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000782 6,015 individuals African unspecified UKB
PSS000783 1,080 individuals East Asian UKB
PSS000784 23,562 individuals European Non-British White UKB
PSS000785 7,336 individuals South Asian UKB
PSS000786 63,745 individuals European
(British)
UKB