Trait: urea measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0011005
Description Quantification of urea in a sample.
Trait category
Other measurement
Mapped term PMID:33283231

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS001980
(portability-PLR_log_urea)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Urea urea measurement 56,782
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001980/ScoringFiles/PGS001980.txt.gz
PGS002198
(portability-ldpred2_log_urea)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Urea urea measurement 820,118
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002198/ScoringFiles/PGS002198.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010715 PGS001980
(portability-PLR_log_urea)
PSS009468|
European Ancestry|
18,989 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.2537 [0.2404, 0.267] sex, age, birth date, deprivation index, 16 PCs
PPM010717 PGS001980
(portability-PLR_log_urea)
PSS008796|
European Ancestry|
6,320 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.2435 [0.2201, 0.2665] sex, age, birth date, deprivation index, 16 PCs
PPM010718 PGS001980
(portability-PLR_log_urea)
PSS008570|
Greater Middle Eastern Ancestry|
1,124 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.2276 [0.1709, 0.2828] sex, age, birth date, deprivation index, 16 PCs
PPM010719 PGS001980
(portability-PLR_log_urea)
PSS008348|
South Asian Ancestry|
6,003 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.2101 [0.1858, 0.2342] sex, age, birth date, deprivation index, 16 PCs
PPM010720 PGS001980
(portability-PLR_log_urea)
PSS008125|
East Asian Ancestry|
1,715 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.1944 [0.1481, 0.2398] sex, age, birth date, deprivation index, 16 PCs
PPM010721 PGS001980
(portability-PLR_log_urea)
PSS007912|
African Ancestry|
2,345 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.16 [0.1202, 0.1994] sex, age, birth date, deprivation index, 16 PCs
PPM010722 PGS001980
(portability-PLR_log_urea)
PSS009016|
African Ancestry|
3,655 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.0842 [0.0518, 0.1164] sex, age, birth date, deprivation index, 16 PCs
PPM010716 PGS001980
(portability-PLR_log_urea)
PSS009242|
European Ancestry|
3,950 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.2562 [0.2268, 0.2852] sex, age, birth date, deprivation index, 16 PCs
PPM012431 PGS002198
(portability-ldpred2_log_urea)
PSS009468|
European Ancestry|
18,989 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.2506 [0.2372, 0.2639] sex, age, birth date, deprivation index, 16 PCs
PPM012432 PGS002198
(portability-ldpred2_log_urea)
PSS009242|
European Ancestry|
3,950 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.2538 [0.2243, 0.2828] sex, age, birth date, deprivation index, 16 PCs
PPM012433 PGS002198
(portability-ldpred2_log_urea)
PSS008796|
European Ancestry|
6,320 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.2434 [0.2201, 0.2665] sex, age, birth date, deprivation index, 16 PCs
PPM012434 PGS002198
(portability-ldpred2_log_urea)
PSS008570|
Greater Middle Eastern Ancestry|
1,124 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.229 [0.1723, 0.2842] sex, age, birth date, deprivation index, 16 PCs
PPM012436 PGS002198
(portability-ldpred2_log_urea)
PSS008125|
East Asian Ancestry|
1,715 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.1944 [0.1482, 0.2398] sex, age, birth date, deprivation index, 16 PCs
PPM012437 PGS002198
(portability-ldpred2_log_urea)
PSS007912|
African Ancestry|
2,345 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.1588 [0.1189, 0.1982] sex, age, birth date, deprivation index, 16 PCs
PPM012438 PGS002198
(portability-ldpred2_log_urea)
PSS009016|
African Ancestry|
3,655 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.0872 [0.0548, 0.1194] sex, age, birth date, deprivation index, 16 PCs
PPM012435 PGS002198
(portability-ldpred2_log_urea)
PSS008348|
South Asian Ancestry|
6,003 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Urea Partial Correlation (partial-r): 0.2054 [0.181, 0.2296] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS007912 2,345 individuals African American or Afro-Caribbean Carribean UKB
PSS008796 6,320 individuals European Italy (South Europe) UKB
PSS009016 3,655 individuals African unspecified Nigeria (West Africa) UKB
PSS008570 1,124 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009242 3,950 individuals European Poland (NE Europe) UKB
PSS009468 18,989 individuals European UK (+ Ireland) UKB
PSS008125 1,715 individuals East Asian China (East Asia) UKB
PSS008348 6,003 individuals South Asian India (South Asia) UKB