Trait: sitting height measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0011011
Description Quantification of some aspect of height, when assuming a sitting position.
Trait category
Other measurement
Mapped term PMID:33623009

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS000969
(GBE_INI20015)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Sitting height sitting height measurement 36,345
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000969/ScoringFiles/PGS000969.txt.gz
PGS002005
(portability-PLR_sitting_height)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Sitting height sitting height measurement 118,423
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002005/ScoringFiles/PGS002005.txt.gz
PGS002224
(portability-ldpred2_sitting_height)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Sitting height sitting height measurement 910,252
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002224/ScoringFiles/PGS002224.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007665 PGS000969
(GBE_INI20015)
PSS004888|
European Ancestry|
24,825 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sitting height : 0.55998 [0.5518, 0.56815]
Incremental R2 (full-covars): 0.12693
PGS R2 (no covariates): 0.13335 [0.12549, 0.14121]
age, sex, UKB array type, Genotype PCs
PPM007666 PGS000969
(GBE_INI20015)
PSS004889|
South Asian Ancestry|
7,645 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sitting height : 0.52117 [0.50586, 0.53647]
Incremental R2 (full-covars): 0.06153
PGS R2 (no covariates): 0.07384 [0.0627, 0.08499]
age, sex, UKB array type, Genotype PCs
PPM007667 PGS000969
(GBE_INI20015)
PSS004890|
European Ancestry|
67,301 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sitting height : 0.56224 [0.55729, 0.5672]
Incremental R2 (full-covars): 0.12957
PGS R2 (no covariates): 0.1276 [0.1229, 0.1323]
age, sex, UKB array type, Genotype PCs
PPM007663 PGS000969
(GBE_INI20015)
PSS004886|
African Ancestry|
6,403 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sitting height : 0.3682 [0.34957, 0.38684]
Incremental R2 (full-covars): 0.01039
PGS R2 (no covariates): 0.02603 [0.01839, 0.03367]
age, sex, UKB array type, Genotype PCs
PPM007664 PGS000969
(GBE_INI20015)
PSS004887|
East Asian Ancestry|
1,698 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sitting height : 0.49052 [0.45671, 0.52434]
Incremental R2 (full-covars): 0.04748
PGS R2 (no covariates): 0.07798 [0.05358, 0.10237]
age, sex, UKB array type, Genotype PCs
PPM010914 PGS002005
(portability-PLR_sitting_height)
PSS009490|
European Ancestry|
19,908 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.5055 [0.4951, 0.5158] sex, age, birth date, deprivation index, 16 PCs
PPM010915 PGS002005
(portability-PLR_sitting_height)
PSS009264|
European Ancestry|
4,122 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.487 [0.4633, 0.51] sex, age, birth date, deprivation index, 16 PCs
PPM010916 PGS002005
(portability-PLR_sitting_height)
PSS008818|
European Ancestry|
6,623 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.4655 [0.4464, 0.4842] sex, age, birth date, deprivation index, 16 PCs
PPM010917 PGS002005
(portability-PLR_sitting_height)
PSS008592|
Greater Middle Eastern Ancestry|
1,175 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.4025 [0.353, 0.4497] sex, age, birth date, deprivation index, 16 PCs
PPM010918 PGS002005
(portability-PLR_sitting_height)
PSS008370|
South Asian Ancestry|
6,123 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.3897 [0.3682, 0.4108] sex, age, birth date, deprivation index, 16 PCs
PPM010919 PGS002005
(portability-PLR_sitting_height)
PSS008146|
East Asian Ancestry|
1,800 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.3397 [0.298, 0.3802] sex, age, birth date, deprivation index, 16 PCs
PPM010920 PGS002005
(portability-PLR_sitting_height)
PSS007934|
African Ancestry|
2,443 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.24 [0.2021, 0.2772] sex, age, birth date, deprivation index, 16 PCs
PPM010921 PGS002005
(portability-PLR_sitting_height)
PSS009038|
African Ancestry|
3,857 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.2113 [0.1808, 0.2413] sex, age, birth date, deprivation index, 16 PCs
PPM012641 PGS002224
(portability-ldpred2_sitting_height)
PSS008592|
Greater Middle Eastern Ancestry|
1,175 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.3911 [0.3411, 0.4389] sex, age, birth date, deprivation index, 16 PCs
PPM012638 PGS002224
(portability-ldpred2_sitting_height)
PSS009490|
European Ancestry|
19,908 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.4963 [0.4858, 0.5067] sex, age, birth date, deprivation index, 16 PCs
PPM012639 PGS002224
(portability-ldpred2_sitting_height)
PSS009264|
European Ancestry|
4,122 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.4829 [0.4591, 0.506] sex, age, birth date, deprivation index, 16 PCs
PPM012640 PGS002224
(portability-ldpred2_sitting_height)
PSS008818|
European Ancestry|
6,623 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.4602 [0.441, 0.479] sex, age, birth date, deprivation index, 16 PCs
PPM012642 PGS002224
(portability-ldpred2_sitting_height)
PSS008370|
South Asian Ancestry|
6,123 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.3797 [0.358, 0.4009] sex, age, birth date, deprivation index, 16 PCs
PPM012643 PGS002224
(portability-ldpred2_sitting_height)
PSS008146|
East Asian Ancestry|
1,800 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.3372 [0.2954, 0.3778] sex, age, birth date, deprivation index, 16 PCs
PPM012645 PGS002224
(portability-ldpred2_sitting_height)
PSS009038|
African Ancestry|
3,857 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.1914 [0.1607, 0.2217] sex, age, birth date, deprivation index, 16 PCs
PPM012644 PGS002224
(portability-ldpred2_sitting_height)
PSS007934|
African Ancestry|
2,443 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sitting height Partial Correlation (partial-r): 0.2361 [0.1982, 0.2734] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009038 3,857 individuals African unspecified Nigeria (West Africa) UKB
PSS009264 4,122 individuals European Poland (NE Europe) UKB
PSS008592 1,175 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009490 19,908 individuals European UK (+ Ireland) UKB
PSS008818 6,623 individuals European Italy (South Europe) UKB
PSS008370 6,123 individuals South Asian India (South Asia) UKB
PSS008146 1,800 individuals East Asian China (East Asia) UKB
PSS007934 2,443 individuals African American or Afro-Caribbean Carribean UKB
PSS004886 6,403 individuals African unspecified UKB
PSS004887 1,698 individuals East Asian UKB
PSS004888 24,825 individuals European non-white British ancestry UKB
PSS004889 7,645 individuals South Asian UKB
PSS004890 67,301 individuals European white British ancestry UKB Testing cohort (heldout set)