Experimental Factor Ontology (EFO) Information | |
Identifier | EFO_0020865 |
Description | Measurement of some parts of the aorta, including ascending aorta distensibility and area. | Trait category |
Cardiovascular measurement
|
Synonym | aortic diagnostic technique |
Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants | Ancestry distribution | Scoring File (FTP Link) |
---|---|---|---|---|---|---|
PGS002267 (PRS89_AA) |
PGP000296 | Pirruccello JP et al. Nat Genet (2021) |
Ascending thoracic aortic diameter | cardiovascular disease biomarker measurement, aortic measurement |
89 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002267/ScoringFiles/PGS002267.txt.gz |
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|---|
PPM012908 | PGS002267 (PRS89_AA) |
PSS009608| European Ancestry| 385,621 individuals |
PGP000296 | Pirruccello JP et al. Nat Genet (2021) |
Reported Trait: Incident thoracic aortic aneurysm or dissection | HR: 1.43 [1.32, 1.54] | — | — | Sex, prevalent diagnoses of type 2 diabetes or hypertension, tobacco smoking history (the number of pack years of tobacco smoking), body mass (the cubic natural spline of body mass index) and age (the cubic natural spline of age at enrollment). | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS009608 | — | Median = 11.2 yrs | [
|
— | European (British, Irish) |
— | UKB | — |