Trait: aortic measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0020865
Description Measurement of some parts of the aorta, including ascending aorta distensibility and area.
Trait category
Cardiovascular measurement
Synonym aortic diagnostic technique

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
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Additional Asian Ancestries
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGP000296 |
Pirruccello JP et al. Nat Genet (2021)
Ascending thoracic aortic diameter cardiovascular disease biomarker measurement,
aortic measurement

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM012908 PGS002267
European Ancestry|
385,621 individuals
PGP000296 |
Pirruccello JP et al. Nat Genet (2021)
Reported Trait: Incident thoracic aortic aneurysm or dissection HR: 1.43 [1.32, 1.54] Sex, prevalent diagnoses of type 2 diabetes or hypertension, tobacco smoking history (the number of pack years of tobacco smoking), body mass (the cubic natural spline of body mass index) and age (the cubic natural spline of age at enrollment).

Evaluated Samples

PGS Sample Set ID
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009608 Median = 11.2 yrs
  • 685 cases
  • , 384,936 controls
(British, Irish)