Trait: duodenitis

Trait Information
Identifier MONDO_0004627
Description Acute or chronic inflammation of the duodenum. Causes include bacterial and viral infections and gastroesophageal reflux disease. Symptoms include vomiting and abdominal pain. [NCIT: P378]
Trait category
Digestive system disorder
Synonyms 3 synonyms
  • duodenitis
  • duodenum inflammation
  • inflammation of duodenum
Mapped terms 8 mapped terms
  • DOID:8643
  • ICD10:K29.8
  • ICD9:535.6
  • ICD9:535.60
  • MESH:D004382
  • NCIT:C94409
  • SCTID:72007001
  • UMLS:C0013298

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS001852
(portability-PLR_535.6)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Duodenitis duodenitis 191
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001852/ScoringFiles/PGS001852.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM009706 PGS001852
(portability-PLR_535.6)
PSS009327|
European Ancestry|
18,600 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Duodenitis Partial Correlation (partial-r): 0.0198 [0.0055, 0.0342] sex, age, birth date, deprivation index, 16 PCs
PPM009707 PGS001852
(portability-PLR_535.6)
PSS009101|
European Ancestry|
3,868 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Duodenitis Partial Correlation (partial-r): 0.0235 [-0.0081, 0.0551] sex, age, birth date, deprivation index, 16 PCs
PPM009708 PGS001852
(portability-PLR_535.6)
PSS008655|
European Ancestry|
6,233 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Duodenitis Partial Correlation (partial-r): -0.0217 [-0.0465, 0.0032] sex, age, birth date, deprivation index, 16 PCs
PPM009709 PGS001852
(portability-PLR_535.6)
PSS008429|
Greater Middle Eastern Ancestry|
1,076 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Duodenitis Partial Correlation (partial-r): 0.002 [-0.0583, 0.0623] sex, age, birth date, deprivation index, 16 PCs
PPM009710 PGS001852
(portability-PLR_535.6)
PSS008209|
South Asian Ancestry|
5,720 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Duodenitis Partial Correlation (partial-r): 0.0315 [0.0055, 0.0574] sex, age, birth date, deprivation index, 16 PCs
PPM009711 PGS001852
(portability-PLR_535.6)
PSS007991|
East Asian Ancestry|
1,684 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Duodenitis Partial Correlation (partial-r): 0.0278 [-0.0203, 0.0757] sex, age, birth date, deprivation index, 16 PCs
PPM009712 PGS001852
(portability-PLR_535.6)
PSS007774|
African Ancestry|
2,298 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Duodenitis Partial Correlation (partial-r): -0.0208 [-0.0618, 0.0203] sex, age, birth date, deprivation index, 16 PCs
PPM009713 PGS001852
(portability-PLR_535.6)
PSS008878|
African Ancestry|
3,648 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Duodenitis Partial Correlation (partial-r): 0.0077 [-0.0249, 0.0402] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009101 3,868 individuals European Poland (NE Europe) UKB
PSS008429 1,076 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008655 6,233 individuals European Italy (South Europe) UKB
PSS009327 18,600 individuals European UK (+ Ireland) UKB
PSS008209 5,720 individuals South Asian India (South Asia) UKB
PSS008878 3,648 individuals African unspecified Nigeria (West Africa) UKB
PSS007991 1,684 individuals East Asian China (East Asia) UKB
PSS007774 2,298 individuals African American or Afro-Caribbean Carribean UKB