Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003453
(PRS43_CLL)
 PGP000448 |
Berndt SI et al. Leukemia (2022)
 Chronic lymphocytic leukemia chronic lymphocytic leukemia 43
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003453/ScoringFiles/PGS003453.txt.gz
PGS004246
(PRS43_lung)
 PGP000542 |
Kim ES et al. NPJ Precis Oncol (2023)
 Lung cancer lung carcinoma 43
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004246/ScoringFiles/PGS004246.txt.gz
PGS000050
(PRS44)
 PGP000035 |
Wen W et al. Breast Cancer Res (2016)
 Breast cancer breast carcinoma 44
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000050/ScoringFiles/PGS000050.txt.gz
PGS000604
(PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of testis testicular carcinoma 44
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000604/ScoringFiles/PGS000604.txt.gz
PGS000648
(PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Chronic lymphocytic leukemia chronic lymphocytic leukemia 44
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000648/ScoringFiles/PGS000648.txt.gz
PGS000718
(PRPBB_44)
 PGP000134 |
Lanfear DE et al. Circ Heart Fail (2020)
 Beta-blocker survival benefit response to beta blocker 44
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000718/ScoringFiles/PGS000718.txt.gz
PGS000735
(PRS_PR)
 PGP000144 |
Tadros R et al. Eur Heart J (2019)
 PR interval PR interval 44
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000735/ScoringFiles/PGS000735.txt.gz
PGS002728
(PRS_hip)
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Hip osteoarthritis osteoarthritis, hip 44
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002728/ScoringFiles/PGS002728.txt.gz
PGS003763
(PRS44_PD)
 PGP000486 |
Zheng Z et al. JAMA Neurol (2023)
 Parkinson's disease Parkinson disease 44
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003763/ScoringFiles/PGS003763.txt.gz
PGS003855
(PRS44_LDL)
 PGP000493 |
Li J et al. JAMA Netw Open (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 44
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003855/ScoringFiles/PGS003855.txt.gz
PGS004898
(PRS_AD)
 PGP000624 |
Vasiljevic E et al. Alzheimers Dement (2023)
 Alzheimer's disease Alzheimer disease 44
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004898/ScoringFiles/PGS004898.txt.gz
PGS005105
(PRSAFR_ER+)
 PGP000694 |
Jia G et al. Nat Genet (2024)
 ER-positive breast cancer estrogen-receptor positive breast cancer 44
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005105/ScoringFiles/PGS005105.txt.gz
PGS000357
(PRSWEB_PHECODE145_C3-LIP-ORAL-PHARYNX_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Oral cavity cancer oral cavity cancer 45
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000357/ScoringFiles/PGS000357.txt.gz
PGS000593
(PRSWEB_PHECODE187_C3-MALE-GENITAL_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Cancer of other male genital organs male reproductive organ cancer 45
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000593/ScoringFiles/PGS000593.txt.gz
PGS000743
(PRS_melanoma)
 PGP000151 |
Cust AE et al. J Invest Dermatol (2018)
 Melanoma melanoma 45
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000743/ScoringFiles/PGS000743.txt.gz
PGS001026
(GBE_HC83)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Forearm or wrist fracture upper extremity fracture 45
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001026/ScoringFiles/PGS001026.txt.gz
PGS001776
(PRS45_CC)
 PGP000256 |
Gafni A et al. PLoS One (2021)
 Colorectal cancer colorectal cancer 45
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001776/ScoringFiles/PGS001776.txt.gz
PGS001826
(portability-PLR_286.12)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Congenital deficiency of other clotting factors (including factor VII) congenital vitamin K-dependent coagulation factors deficiency 45
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001826/ScoringFiles/PGS001826.txt.gz
PGS002253
(Melanoma_PRS45)
 PGP000274 |
Steinberg J et al. Br J Dermatol (2021)
 Melanoma melanoma 45
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002253/ScoringFiles/PGS002253.txt.gz
PGS003095
(ExPRSweb_T2D_29358691-GCST005413_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 45
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003095/ScoringFiles/PGS003095.txt.gz
PGS000059
(CHD46)
 PGP000044 |
Hajek C et al. Circ Genom Precis Med (2018)
 Coronary heart disease coronary artery disease 46
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000059/ScoringFiles/PGS000059.txt.gz
PGS000060
(GRS_HDL)
 PGP000045 |
Johnson L et al. PLoS One (2015)
 HDL cholesterol high density lipoprotein cholesterol measurement 46
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000060/ScoringFiles/PGS000060.txt.gz
PGS000741
(PCa_PHS2)
 PGP000149 |
Huynh-Le MP et al. Nat Commun (2021)
 Prostate cancer prostate carcinoma 46
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000741/ScoringFiles/PGS000741.txt.gz
PGS000813
(PRS46_melanoma)
 PGP000197 |
Potjer TP et al. J Med Genet (2020)
 Melanoma melanoma 46
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000813/ScoringFiles/PGS000813.txt.gz
PGS003096
(ExPRSweb_T2D_29358691-GCST005413_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 46
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003096/ScoringFiles/PGS003096.txt.gz
PGS003217
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_DBSLMM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Sleep apnea sleep apnea 46
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003217/ScoringFiles/PGS003217.txt.gz
PGS003748
(GRS46_CPD)
 PGP000471 |
Tran JH et al. Transl Vis Sci Technol (2023)
 Cigarettes smoked per day cigarettes per day measurement 46
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003748/ScoringFiles/PGS003748.txt.gz
PGS004225
(PRS46_T2DEastAsia)
 PGP000526 |
Liu J et al. Nutrients (2023)
 Type 2 diabetes type 2 diabetes mellitus 46
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004225/ScoringFiles/PGS004225.txt.gz
PGS000575
(PRSWEB_PHECODE185_C61_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Prostate cancer prostate carcinoma 47
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000575/ScoringFiles/PGS000575.txt.gz
PGS000730
(PRS_BCC)
 PGP000138 |
Fontanillas P et al. Nat Commun (2021)
 Basal cell carcinoma basal cell carcinoma 47
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000730/ScoringFiles/PGS000730.txt.gz - Check Terms/Licenses
PGS000964
(GBE_HC176)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Slipped disc Epiphyses, Slipped 47
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000964/ScoringFiles/PGS000964.txt.gz
PGS001761
(GBE_INI25558)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 WA MO in tract middle cerebellar peduncle neuroimaging measurement,
brain volume		 47
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001761/ScoringFiles/PGS001761.txt.gz
PGS002269
(PRS47_AMD)
 PGP000299 |
Zekavat SM et al. Ophthalmology (2022)
 Age-related macular degeneration age-related macular degeneration 47
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002269/ScoringFiles/PGS002269.txt.gz
PGS003414
(PRS47_RBD)
 PGP000427 |
Krohn L et al. Nat Commun (2022)
 REM sleep behavior disorder REM sleep behavior disorder 47
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003414/ScoringFiles/PGS003414.txt.gz
PGS000150
(GRS48)
 PGP000073 |
Weigl K et al. Gastroenterology (2018)
 Colorectal cancer colorectal cancer 48
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000150/ScoringFiles/PGS000150.txt.gz
PGS000738
(CONFIRMED_PGS)
 PGP000145 |
Roberts GHL et al. Am J Hum Genet (2019)
 Vitiligo Vitiligo 48
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000738/ScoringFiles/PGS000738.txt.gz
PGS000869
(T1D_48)
 PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 48
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000869/ScoringFiles/PGS000869.txt.gz
PGS001123
(GBE_BIN100240)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Coffee consumption coffee consumption measurement 48
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001123/ScoringFiles/PGS001123.txt.gz
PGS002297
(GRS48_lpa)
 PGP000327 |
Coassin S et al. Circ Genom Precis Med (2022)
 Lipoprotein A levels lipoprotein A measurement 48
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002297/ScoringFiles/PGS002297.txt.gz
PGS003290
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate		 48
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003290/ScoringFiles/PGS003290.txt.gz
PGS003641
(L_CA4_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA4 head volume hippocampal CA4 volume 48
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003641/ScoringFiles/PGS003641.txt.gz
PGS000313
(GRS49_Lp(a))
 PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
 Lipoprotein A lipoprotein A measurement 49
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000313/ScoringFiles/PGS000313.txt.gz
PGS000489
(PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 49
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000489/ScoringFiles/PGS000489.txt.gz
PGS000490
(PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 49
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000490/ScoringFiles/PGS000490.txt.gz
PGS000494
(PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 49
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000494/ScoringFiles/PGS000494.txt.gz
PGS000569
(PRSWEB_PHECODE185_C3-PROSTATE_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Prostate cancer prostate carcinoma 49
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000569/ScoringFiles/PGS000569.txt.gz
PGS000733
(PHS46+African)
 PGP000139 |
Karunamuni RA et al. Int J Cancer (2020)
 Prostate cancer prostate carcinoma 49
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000733/ScoringFiles/PGS000733.txt.gz
PGS002264
(PRS_Combined)
 PGP000293 |
Sharma S et al. Gastroenterology (2022)
 Pancreatic ductal adenocarcinoma pancreatic ductal adenocarcinoma 49
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002264/ScoringFiles/PGS002264.txt.gz
PGS003291
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate		 49
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003291/ScoringFiles/PGS003291.txt.gz
PGS003760
(PRS49_EOCRC)
 PGP000480 |
Wang H et al. Genome Med (2023)
 Early onset colorectal cancer colorectal cancer 49
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003760/ScoringFiles/PGS003760.txt.gz
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