Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS019635
(TPMI_706.1_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acne acne 273,955
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019635/ScoringFiles/PGS019635.txt.gz
PGS019636
(TPMI_706.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acne acne 17,458
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019636/ScoringFiles/PGS019636.txt.gz
PGS019637
(TPMI_706.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acne acne 983,822
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019637/ScoringFiles/PGS019637.txt.gz
PGS019638
(TPMI_706.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acne acne 961,798
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019638/ScoringFiles/PGS019638.txt.gz
PGS001785
(1kgeur_gbmi_leaveUKBBout_AcApp_pst_eff_a1_b0.5_phiauto)
 PGP000262 |
Wang Y et al. Cell Genom (2023)
 Acute appendicitis appendicitis 911,334
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001785/ScoringFiles/PGS001785.txt.gz
PGS001369
(GBE_HC1090)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Acute appendicitis (time-to-event) appendicitis 4
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001369/ScoringFiles/PGS001369.txt.gz
PGS019240
(TPMI_433.6_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acute but ill defined cerebrovascular disease cerebrovascular disorder 356,084
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019240/ScoringFiles/PGS019240.txt.gz
PGS019241
(TPMI_433.6_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acute but ill defined cerebrovascular disease cerebrovascular disorder 939,874
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019241/ScoringFiles/PGS019241.txt.gz
PGS019242
(TPMI_433.6_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acute but ill defined cerebrovascular disease cerebrovascular disorder 436,050
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019242/ScoringFiles/PGS019242.txt.gz
PGS019243
(TPMI_433.6_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acute but ill defined cerebrovascular disease cerebrovascular disorder 983,814
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019243/ScoringFiles/PGS019243.txt.gz
PGS019244
(TPMI_433.6_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acute but ill defined cerebrovascular disease cerebrovascular disorder 999,333
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019244/ScoringFiles/PGS019244.txt.gz
PGS003448
(PRS15_ALL)
 PGP000448 |
Berndt SI et al. Leukemia (2022)
 Acute lymphoblastic leukemia acute lymphoblastic leukemia 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003448/ScoringFiles/PGS003448.txt.gz
PGS001314
(GBE_HC938)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Acute myocardial infarction (time-to-event) myocardial infarction 1,108
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001314/ScoringFiles/PGS001314.txt.gz
PGS019955
(PRS1308_AR)
 PGP000845 |
Cao R et al. PLoS One (2024)
 Acute rejection after kidney transplantation renal transplant outcome measurement 1,308
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019955/ScoringFiles/PGS019955.txt.gz
PGS019260
(TPMI_465_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acute upper respiratory infections of multiple or unspecified sites respiratory tract infectious disorder 407,569
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019260/ScoringFiles/PGS019260.txt.gz
PGS019261
(TPMI_465_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acute upper respiratory infections of multiple or unspecified sites respiratory tract infectious disorder 939,886
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019261/ScoringFiles/PGS019261.txt.gz
PGS019262
(TPMI_465_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acute upper respiratory infections of multiple or unspecified sites respiratory tract infectious disorder 517,153
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019262/ScoringFiles/PGS019262.txt.gz
PGS019263
(TPMI_465_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acute upper respiratory infections of multiple or unspecified sites respiratory tract infectious disorder 983,822
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019263/ScoringFiles/PGS019263.txt.gz
PGS019264
(TPMI_465_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acute upper respiratory infections of multiple or unspecified sites respiratory tract infectious disorder 897,911
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019264/ScoringFiles/PGS019264.txt.gz
PGS003849
(PRSaddiction-rf)
 PGP000490 |
Hatoum AS et al. Nat Ment Health (2023)
 Addiction risk factors substance-related disorder 584,753
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003849/ScoringFiles/PGS003849.txt.gz
PGS005215
(addiction_rf)
 PGP000731 |
Deng WQ et al. Alcohol Alcohol (2024)
 Addiction risk factors substance-related disorder 11,627
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005215/ScoringFiles/PGS005215.txt.gz
PGS005235
(F4_Adiposity)
 PGP000739 |
Arehart CH et al. Nat Commun (2025)
 Adiposity obesity disorder 709,828
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005235/ScoringFiles/PGS005235.txt.gz
PGS000217
(ADM)
 PGP000089 |
Folkersen L et al. Nat Metab (2020)
 Adrenomedullin (ADM) serum levels blood protein amount 552,254
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000217/ScoringFiles/PGS000217.txt.gz
PGS000034
(GRS_BMI)
 PGP000021 |
Song M et al. Diabetes (2017)
 Adult body mass index (BMI) body mass index 97
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000034/ScoringFiles/PGS000034.txt.gz
PGS000717
(PGS557_albs)
 PGP000132 |
Richardson TG et al. BMJ (2020)
 Adult life body size body mass index 557
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000717/ScoringFiles/PGS000717.txt.gz
PGS000758
(LASSO_Height)
 PGP000163 |
Lu T et al. J Clin Endocrinol Metab (2021)
 Adult standing height body height 33,938
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000758/ScoringFiles/PGS000758.txt.gz - Check Terms/Licenses
PGS001370
(GBE_INI3786)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Age asthma diagnosed asthma 922
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001370/ScoringFiles/PGS001370.txt.gz
PGS001912
(portability-PLR_F_age_first_birth)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Age at first live birth age at first birth measurement 15,201
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001912/ScoringFiles/PGS001912.txt.gz
PGS002127
(portability-ldpred2_F_age_first_birth)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Age at first live birth age at first birth measurement 848,784
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002127/ScoringFiles/PGS002127.txt.gz
PGS003505
(cont-decay-F_age_first_birth)
 PGP000457 |
Ding Y et al. Nature (2023)
 Age at first live birth age at first birth measurement 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003505/ScoringFiles/PGS003505.txt.gz
PGS001007
(GBE_INI2139)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Age at first sexual intercourse age at first sexual intercourse measurement 9,997
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001007/ScoringFiles/PGS001007.txt.gz
PGS002310
(repro_MENARCHE_AGE.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002310/ScoringFiles/PGS002310.txt.gz
PGS002382
(repro_MENARCHE_AGE.P+T.0.0001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 6,332
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002382/ScoringFiles/PGS002382.txt.gz
PGS002431
(repro_MENARCHE_AGE.P+T.0.001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 21,880
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002431/ScoringFiles/PGS002431.txt.gz
PGS002480
(repro_MENARCHE_AGE.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 115,583
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002480/ScoringFiles/PGS002480.txt.gz
PGS002529
(repro_MENARCHE_AGE.P+T.1e-06)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 1,546
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002529/ScoringFiles/PGS002529.txt.gz
PGS002578
(repro_MENARCHE_AGE.P+T.5e-08)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 891
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002578/ScoringFiles/PGS002578.txt.gz
PGS002627
(repro_MENARCHE_AGE.PolyFun-pred)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 831,098
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002627/ScoringFiles/PGS002627.txt.gz
PGS002676
(repro_MENARCHE_AGE.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 988,120
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002676/ScoringFiles/PGS002676.txt.gz
PGS002815
(ExPRSweb_AgeAtMenarche_ieu-a-1095_LASSOSUM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menarche age at menarche 137,734
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002815/ScoringFiles/PGS002815.txt.gz
PGS002816
(ExPRSweb_AgeAtMenarche_ieu-a-1095_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menarche age at menarche 13,852
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002816/ScoringFiles/PGS002816.txt.gz
PGS002817
(ExPRSweb_AgeAtMenarche_ieu-a-1095_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menarche age at menarche 13,852
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002817/ScoringFiles/PGS002817.txt.gz
PGS002818
(ExPRSweb_AgeAtMenarche_ieu-a-1095_DBSLMM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menarche age at menarche 991,712
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002818/ScoringFiles/PGS002818.txt.gz
PGS002819
(ExPRSweb_AgeAtMenarche_ieu-a-1095_PRSCS_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menarche age at menarche 895,562
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002819/ScoringFiles/PGS002819.txt.gz
PGS002820
(ExPRSweb_AgeAtMenopause_ieu-a-1004_LASSOSUM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menopause age at menopause 99,745
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002820/ScoringFiles/PGS002820.txt.gz
PGS002821
(ExPRSweb_AgeAtMenopause_ieu-a-1004_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menopause age at menopause 159
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002821/ScoringFiles/PGS002821.txt.gz
PGS002822
(ExPRSweb_AgeAtMenopause_ieu-a-1004_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menopause age at menopause 159
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002822/ScoringFiles/PGS002822.txt.gz
PGS002823
(ExPRSweb_AgeAtMenopause_ieu-a-1004_DBSLMM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menopause age at menopause 1,379,304
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002823/ScoringFiles/PGS002823.txt.gz
PGS002824
(ExPRSweb_AgeAtMenopause_ieu-a-1004_PRSCS_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menopause age at menopause 894,484
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002824/ScoringFiles/PGS002824.txt.gz
PGS001371
(GBE_INI2976)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Age diabetes diagnosed age at diagnosis,
diabetes mellitus		 26
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001371/ScoringFiles/PGS001371.txt.gz
Showing 51 to 100 of 6982 rows