Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000886
(GLGC_2021_AFR_LDL_PRS_weights_PRS-CS)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,222,318
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000886/ScoringFiles/PGS000886.txt.gz
PGS000885
(eGFR_TOPSNPPRS)
 PGP000229 |
Yu Z et al. J Am Soc Nephrol (2021)
 Estimated glomerular filtration rate glomerular filtration rate 1,460
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000885/ScoringFiles/PGS000885.txt.gz
PGS000884
(eGFR_PTPRS)
 PGP000229 |
Yu Z et al. J Am Soc Nephrol (2021)
 Estimated glomerular filtration rate glomerular filtration rate 40,042
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000884/ScoringFiles/PGS000884.txt.gz
PGS000883
(eGFR_LDpredPRS)
 PGP000229 |
Yu Z et al. J Am Soc Nephrol (2021)
 Estimated glomerular filtration rate glomerular filtration rate 1,477,661
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000883/ScoringFiles/PGS000883.txt.gz
PGS000882
(25OHD_SBayesR_PGS)
 PGP000228 |
Revez JA et al. Nat Commun (2020)
 25-hydroxyvitamin D vitamin D amount 1,094,650
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000882/ScoringFiles/PGS000882.txt.gz
PGS000881
(GRS72_PCa)
 PGP000227 |
Xu J et al. Prostate (2021)
 Prostate cancer prostate carcinoma 72
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000881/ScoringFiles/PGS000881.txt.gz
PGS000880
(PRS18_LC)
 PGP000226 |
Xie J et al. Sleep (2021)
 Lung cancer lung carcinoma 18
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000880/ScoringFiles/PGS000880.txt.gz
PGS000879
(PRS146_IOP)
 PGP000225 |
Qassim A et al. Ophthalmology (2020)
 Intraocular pressure intraocular pressure measurement 146
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000879/ScoringFiles/PGS000879.txt.gz
PGS000878
(PRS4_PC)
 PGP000224 |
Oh JJ et al. Front Oncol (2020)
 Prostate cancer prostate carcinoma 4
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000878/ScoringFiles/PGS000878.txt.gz
PGS000877
(uwGRS53_IR)
 PGP000223 |
Lotta LA et al. Nat Genet (2016)
 Insulin resistance insulin resistance 53
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000877/ScoringFiles/PGS000877.txt.gz
PGS000876
(PRS31_AD)
 PGP000222 |
Leonenko G et al. Ann Clin Transl Neurol (2019)
 Alzheimer's disease Alzheimer disease 31
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000876/ScoringFiles/PGS000876.txt.gz
PGS000875
(PGS36_LDLc)
 PGP000221 |
Leal LG et al. Mol Genet Genomic Med (2020)
 LDL cholesterol low density lipoprotein cholesterol measurement 36
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000875/ScoringFiles/PGS000875.txt.gz
PGS000874
(PRS41_CLL)
 PGP000220 |
Kleinstern G et al. Blood (2018)
 Chronic lymphocytic leukemia chronic lymphocytic leukemia 41
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000874/ScoringFiles/PGS000874.txt.gz
PGS000873
(SNP143)
 PGP000216 |
Brentnall AR et al. Int J Cancer (2019)
 Breast cancer breast carcinoma 143
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000873/ScoringFiles/PGS000873.txt.gz
PGS000872
(PRS-5)
 PGP000215 |
Bianco C et al. J Hepatol (2020)
 Non-alcoholic fatty liver disease non-alcoholic fatty liver disease 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000872/ScoringFiles/PGS000872.txt.gz
PGS000871
(IS_14)
 PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
 Insulin secretion insulin secretion trait 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000871/ScoringFiles/PGS000871.txt.gz
PGS000870
(CFRD_18)
 PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
 Cystic fibrosis related diabetes complication 18
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000870/ScoringFiles/PGS000870.txt.gz
PGS000869
(T1D_48)
 PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 48
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000869/ScoringFiles/PGS000869.txt.gz
PGS000868
(T2D_221)
 PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 221
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000868/ScoringFiles/PGS000868.txt.gz
PGS000867
(GRS10_Allergy)
 PGP000213 |
Arabkhazaeli A et al. Pediatr Allergy Immunol (2017)
 Allergy allergic disease 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000867/ScoringFiles/PGS000867.txt.gz
PGS000866
(PRS-HFC_SOS)
 PGP000212 |
Dongiovanni P et al. J Intern Med (2017)
 Hepatic fat content liver fat measurement 4
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000866/ScoringFiles/PGS000866.txt.gz
PGS000865
(PRS-HFC)
 PGP000212 |
Dongiovanni P et al. J Intern Med (2017)
 Hepatic fat content liver fat measurement 4
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000865/ScoringFiles/PGS000865.txt.gz
PGS000864
(T2D-gPRS)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 389,243
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000864/ScoringFiles/PGS000864.txt.gz
PGS000863
(Cardiovascular)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Cardiovascular disease cardiovascular disease 330
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000863/ScoringFiles/PGS000863.txt.gz
PGS000862
(DR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Diabetic Retinopathy diabetic retinopathy 30
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000862/ScoringFiles/PGS000862.txt.gz
PGS000861
(UACR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Urine Albumin-to-Creatinine ratio urinary albumin to creatinine ratio 93
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000861/ScoringFiles/PGS000861.txt.gz
PGS000860
(eGFR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Estimated glomerular filtration rate glomerular filtration rate 625
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000860/ScoringFiles/PGS000860.txt.gz
PGS000859
(CKD)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Chronic kidney disease chronic kidney disease 34
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000859/ScoringFiles/PGS000859.txt.gz
PGS000858
(T2D_Proinsulin)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with proinsulin levels) type 2 diabetes mellitus 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000858/ScoringFiles/PGS000858.txt.gz
PGS000857
(T2D_Obesity)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with obesity) type 2 diabetes mellitus 4
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000857/ScoringFiles/PGS000857.txt.gz
PGS000856
(T2D_LiverLipids)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with liver lipids) type 2 diabetes mellitus 3
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000856/ScoringFiles/PGS000856.txt.gz
PGS000855
(T2D_Lipodystrophy)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with lipodystrophy) type 2 diabetes mellitus 18
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000855/ScoringFiles/PGS000855.txt.gz
PGS000854
(T2D_BetaCell)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with beta cell function) type 2 diabetes mellitus 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000854/ScoringFiles/PGS000854.txt.gz
PGS000853
(T2D_Insulin_Secretion_2)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 21
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000853/ScoringFiles/PGS000853.txt.gz
PGS000852
(T2D_Insulin_Secretion_1)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000852/ScoringFiles/PGS000852.txt.gz
PGS000851
(T2D_Insulin_Action_Secretion)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin action/secretion) type 2 diabetes mellitus 37
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000851/ScoringFiles/PGS000851.txt.gz
PGS000850
(T2D_Insulin_Action)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin action) type 2 diabetes mellitus 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000850/ScoringFiles/PGS000850.txt.gz
PGS000849
(T2D_Impaired_Lipids)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with impaired lipids) type 2 diabetes mellitus 3
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000849/ScoringFiles/PGS000849.txt.gz
PGS000848
(T2D_Adiposity)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with adiposity) type 2 diabetes mellitus 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000848/ScoringFiles/PGS000848.txt.gz
PGS000847
(TG)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Triglycerides (TG) triglyceride measurement 201
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000847/ScoringFiles/PGS000847.txt.gz
PGS000846
(LDL)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 275
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000846/ScoringFiles/PGS000846.txt.gz
PGS000845
(HDL)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 HDL cholesterol high density lipoprotein cholesterol measurement 303
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000845/ScoringFiles/PGS000845.txt.gz
PGS000844
(VAT_Mass)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Predicted visceral adipose tissue visceral adipose tissue quantity 518
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000844/ScoringFiles/PGS000844.txt.gz
PGS000843
(WHRadjBMI)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 WHR adjusted for BMI BMI-adjusted waist-hip ratio 63
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000843/ScoringFiles/PGS000843.txt.gz
PGS000842
(WHR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Waist-hip ratio waist-hip ratio 39
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000842/ScoringFiles/PGS000842.txt.gz
PGS000841
(BMI)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Body mass index (BMI) body mass index 122
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000841/ScoringFiles/PGS000841.txt.gz
PGS000840
(Fasting_Proinsulin)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Fasting Proinsulin proinsulin measurement 223
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000840/ScoringFiles/PGS000840.txt.gz
PGS000839
(2H_Glucose)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Two hour glucose during OGTT glucose tolerance test 219
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000839/ScoringFiles/PGS000839.txt.gz
PGS000838
(Fasting_Glucose)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Fasting glucose blood glucose amount 224
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000838/ScoringFiles/PGS000838.txt.gz
PGS000837
(ISI)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Insulin sensitivity index insulin sensitivity measurement 219
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000837/ScoringFiles/PGS000837.txt.gz
Showing 4251 to 4300 of 5134 rows