Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000220
(CCL20)
 PGP000089 |
Folkersen L et al. Nat Metab (2020)
 C-C motif chemokine 20 (CCL20) serum levels blood protein amount 551,989
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000220/ScoringFiles/PGS000220.txt.gz
PGS000228
(CTSL1)
 PGP000089 |
Folkersen L et al. Nat Metab (2020)
 Cathepsin L1 (CTSL1) serum levels blood protein amount 552,084
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000228/ScoringFiles/PGS000228.txt.gz
PGS000227
(CTSD)
 PGP000089 |
Folkersen L et al. Nat Metab (2020)
 Cathepsin D (CTSD) serum levels blood protein amount 552,134
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000227/ScoringFiles/PGS000227.txt.gz
PGS001302
(GBE_HC25)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Cataract cataract 1,214
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001302/ScoringFiles/PGS001302.txt.gz
PGS001837
(portability-PLR_366)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Cataract cataract 11,617
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001837/ScoringFiles/PGS001837.txt.gz
PGS002044
(portability-ldpred2_366)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Cataract cataract 711,169
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002044/ScoringFiles/PGS002044.txt.gz
PGS005142
(Cataract (PRS-CS; EAS))
 PGP000704 |
Jung HU et al. Commun Biol (2025)
 Cataract cataract 908,465
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005142/ScoringFiles/PGS005142.txt.gz
PGS005149
(Cataract (PRS-CSx; EAS+EUR))
 PGP000704 |
Jung HU et al. Commun Biol (2025)
 Cataract cataract 908,465
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005149/ScoringFiles/PGS005149.txt.gz
PGS000117
(CVD_EJ2020)
 PGP000054 |
Elliott J et al. JAMA (2020)
 Cardiovascular disease cardiovascular disease 297,862
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000117/ScoringFiles/PGS000117.txt.gz - Check Terms/Licenses
PGS000863
(Cardiovascular)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Cardiovascular disease cardiovascular disease 330
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000863/ScoringFiles/PGS000863.txt.gz
PGS002316
(disease_CARDIOVASCULAR.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Cardiovascular disease cardiovascular disease 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002316/ScoringFiles/PGS002316.txt.gz
PGS002361
(disease_CARDIOVASCULAR.BOLT-LMM-BBJ)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Cardiovascular disease cardiovascular disease 920,929
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002361/ScoringFiles/PGS002361.txt.gz
PGS002388
(disease_CARDIOVASCULAR.P+T.0.0001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Cardiovascular disease cardiovascular disease 5,621
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002388/ScoringFiles/PGS002388.txt.gz
PGS002437
(disease_CARDIOVASCULAR.P+T.0.001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Cardiovascular disease cardiovascular disease 20,431
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002437/ScoringFiles/PGS002437.txt.gz
PGS002486
(disease_CARDIOVASCULAR.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Cardiovascular disease cardiovascular disease 110,640
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002486/ScoringFiles/PGS002486.txt.gz
PGS002535
(disease_CARDIOVASCULAR.P+T.1e-06)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Cardiovascular disease cardiovascular disease 1,218
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002535/ScoringFiles/PGS002535.txt.gz
PGS002584
(disease_CARDIOVASCULAR.P+T.5e-08)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Cardiovascular disease cardiovascular disease 637
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002584/ScoringFiles/PGS002584.txt.gz
PGS002633
(disease_CARDIOVASCULAR.PolyFun-pred)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Cardiovascular disease cardiovascular disease 381,036
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002633/ScoringFiles/PGS002633.txt.gz
PGS002682
(disease_CARDIOVASCULAR.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Cardiovascular disease cardiovascular disease 972,965
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002682/ScoringFiles/PGS002682.txt.gz
PGS004238
(wGRS35)
 PGP000535 |
Cheng CF et al. J Gene Med (2021)
 Cardiovascular disease cardiovascular disease 35
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004238/ScoringFiles/PGS004238.txt.gz
PGS003868
(CM_LDpred2_ARB)
 PGP000501 |
Shim I et al. Nature Communications (2023)
 Cardiomyopathy cardiomyopathy 1,010,014
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003868/ScoringFiles/PGS003868.txt.gz
PGS000469
(PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Carcinoma in situ of skin skin carcinoma in situ 1,119,238
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000469/ScoringFiles/PGS000469.txt.gz
PGS000470
(PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Carcinoma in situ of skin skin carcinoma in situ 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000470/ScoringFiles/PGS000470.txt.gz
PGS000471
(PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_LASSOSUM_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Carcinoma in situ of skin skin carcinoma in situ 7
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000471/ScoringFiles/PGS000471.txt.gz
PGS004221
(PRS8_carbohydrate)
 PGP000521 |
Merino J et al. Mol Psychiatry (2023)
 Carbohydrate preference carbohydrate intake measurement 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004221/ScoringFiles/PGS004221.txt.gz
PGS000593
(PRSWEB_PHECODE187_C3-MALE-GENITAL_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Cancer of other male genital organs male reproductive organ cancer 45
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000593/ScoringFiles/PGS000593.txt.gz
PGS000594
(PRSWEB_PHECODE187_C3-MALE-GENITAL_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Cancer of other male genital organs male reproductive organ cancer 97
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000594/ScoringFiles/PGS000594.txt.gz
PGS000543
(PRSWEB_PHECODE184_C3-FEMALE-GENITAL_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Cancer of other female genital organs female reproductive system neoplasm 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000543/ScoringFiles/PGS000543.txt.gz
PGS001250
(GBE_HC1304)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Calculus of kidney and ureter (time-to-event) nephrolithiasis,
ureterolithiasis		 341
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001250/ScoringFiles/PGS001250.txt.gz
PGS000676
(snpnet.Calcium)
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 Calcium [mmol/L] calcium measurement 12,334
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000676/ScoringFiles/PGS000676.txt.gz - Check Terms/Licenses
PGS004332
(X30680.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Calcium (mmol/L) calcium measurement 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004332/ScoringFiles/PGS004332.txt.gz
PGS001893
(portability-PLR_calcium)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Calcium calcium measurement 48,395
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001893/ScoringFiles/PGS001893.txt.gz
PGS002106
(portability-ldpred2_calcium)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Calcium calcium measurement 702,009
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002106/ScoringFiles/PGS002106.txt.gz
PGS004442
(disease.C34.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 C34 (Malignant neoplasm of bronchus and lung) lung carcinoma 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004442/ScoringFiles/PGS004442.txt.gz
PGS004512
(meta.C34.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 C34 (Malignant neoplasm of bronchus and lung) lung carcinoma 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004512/ScoringFiles/PGS004512.txt.gz
PGS000737
(PRS_BrS)
 PGP000144 |
Tadros R et al. Eur Heart J (2019)
 Brugada syndrome Brugada syndrome 3
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000737/ScoringFiles/PGS000737.txt.gz
PGS001779
(BRSprs)
 PGP000260 |
Barc J et al. Nat Genet (2022)
 Brugada syndrome Brugada syndrome 21
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001779/ScoringFiles/PGS001779.txt.gz
PGS000140
(GPpsy)
 PGP000068 |
Cai N et al. Nat Genet (2020)
 Broad Depression (seen a General Practitioner for nerves, anxiety, tension or depression) seeing a general practitioner for nerves, anxiety, tension or depression, self-reported,
depressive disorder		 24,665
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000140/ScoringFiles/PGS000140.txt.gz
PGS000216
(PRS330_TN)
 PGP000088 |
Zhang H et al. Nat Genet (2020)
 Breast cancer intrinsic-like subtype (triple negative) triple-negative breast cancer 330
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000216/ScoringFiles/PGS000216.txt.gz
PGS000214
(PRS330_LumB)
 PGP000088 |
Zhang H et al. Nat Genet (2020)
 Breast cancer intrinsic-like subtype (luminal B-like) luminal B breast carcinoma 330
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000214/ScoringFiles/PGS000214.txt.gz
PGS000213
(PRS330_LumBHER2neg)
 PGP000088 |
Zhang H et al. Nat Genet (2020)
 Breast cancer intrinsic-like subtype (luminal B/HER2-negative-like) HER2 negative breast carcinoma 330
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000213/ScoringFiles/PGS000213.txt.gz
PGS000212
(PRS330_LumA)
 PGP000088 |
Zhang H et al. Nat Genet (2020)
 Breast cancer intrinsic-like subtype (luminal A-like) luminal A breast carcinoma 330
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000212/ScoringFiles/PGS000212.txt.gz
PGS000215
(PRS330_HER2)
 PGP000088 |
Zhang H et al. Nat Genet (2020)
 Breast cancer intrinsic-like subtype (HER2-enriched-like) HER2 Positive Breast Carcinoma 330
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000215/ScoringFiles/PGS000215.txt.gz
PGS000472
(PRSWEB_PHECODE174.1_20001-1002_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 22
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000472/ScoringFiles/PGS000472.txt.gz
PGS000473
(PRSWEB_PHECODE174.1_20001-1002_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 1,111,495
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000473/ScoringFiles/PGS000473.txt.gz
PGS000474
(PRSWEB_PHECODE174.1_20001-1002_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 68
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000474/ScoringFiles/PGS000474.txt.gz
PGS000475
(PRSWEB_PHECODE174.1_20001-1002_LASSOSUM_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 30,041
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000475/ScoringFiles/PGS000475.txt.gz
PGS000476
(PRSWEB_PHECODE174.1_C3-BREAST-3_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 32
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000476/ScoringFiles/PGS000476.txt.gz
PGS000477
(PRSWEB_PHECODE174.1_C3-BREAST-3_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 1,111,495
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000477/ScoringFiles/PGS000477.txt.gz
PGS000478
(PRSWEB_PHECODE174.1_C3-BREAST-3_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 120
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000478/ScoringFiles/PGS000478.txt.gz
Showing 4301 to 4350 of 5134 rows