Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS002828
(ExPRSweb_Alcohol_20403_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Alcohol consumption alcohol consumption measurement 5,498,032
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002828/ScoringFiles/PGS002828.txt.gz
PGS004836
(stroke_PRSmixPlus_eur)
PGP000604 |
Truong B et al. Cell Genom (2024)
Stroke stroke 5,644,266
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004836/ScoringFiles/PGS004836.txt.gz
PGS000379
(PRSWEB_PHECODE153.2_C3-COLON_LASSOSUM_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Colon cancer colon carcinoma 5,715,093
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000379/ScoringFiles/PGS000379.txt.gz
PGS000377
(PRSWEB_PHECODE153.2_C18_LASSOSUM_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Colon cancer colon carcinoma 5,740,814
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000377/ScoringFiles/PGS000377.txt.gz
PGS003576
(AutoImpAll.LifetimeMDD)
PGP000461 |
Dahl A et al. bioRxiv (2022)
|Pre
Major Depressive Disorder (Lifetime) major depressive disorder 5,776,312
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003576/ScoringFiles/PGS003576.txt.gz
PGS003577
(AutoImpOnly.LifetimeMDD)
PGP000461 |
Dahl A et al. bioRxiv (2022)
|Pre
Major Depressive Disorder (Lifetime) major depressive disorder 5,776,312
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003577/ScoringFiles/PGS003577.txt.gz
PGS003584
(SoftImpAll.LifetimeMDD)
PGP000461 |
Dahl A et al. bioRxiv (2022)
|Pre
Major Depressive Disorder (Lifetime) major depressive disorder 5,776,312
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003584/ScoringFiles/PGS003584.txt.gz
PGS003585
(SoftImpOnly.LifetimeMDD)
PGP000461 |
Dahl A et al. bioRxiv (2022)
|Pre
Major Depressive Disorder (Lifetime) major depressive disorder 5,776,312
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003585/ScoringFiles/PGS003585.txt.gz
PGS004780
(height_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Height body height 5,967,476
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004780/ScoringFiles/PGS004780.txt.gz
PGS002725
(GIGASTROKE_iPGS_EAS)
PGP000333 |
Mishra A et al. Nature (2022)
Ischemic stroke stroke,
Ischemic stroke
6,010,730
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002725/ScoringFiles/PGS002725.txt.gz
PGS004832
(sbp_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Systolic blood pressure systolic blood pressure 6,013,177
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004832/ScoringFiles/PGS004832.txt.gz
PGS004848
(tg_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Triglycerides triglyceride measurement 6,127,766
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004848/ScoringFiles/PGS004848.txt.gz
PGS004728
(Basophils_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Basophil count basophil count 6,132,012
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004728/ScoringFiles/PGS004728.txt.gz
PGS004730
(Basophils_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Basophil count basophil count 6,132,012
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004730/ScoringFiles/PGS004730.txt.gz
PGS004812
(Platelets_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Platelet count platelet count 6,146,883
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004812/ScoringFiles/PGS004812.txt.gz
PGS004814
(Platelets_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Platelet count platelet count 6,146,883
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004814/ScoringFiles/PGS004814.txt.gz
PGS004844
(tc_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Total cholesterol total cholesterol measurement 6,149,012
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004844/ScoringFiles/PGS004844.txt.gz
PGS000331
(PRS_AF)
PGP000100 |
Mars N et al. Nat Med (2020)
Atrial fibrillation atrial fibrillation 6,183,494
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000331/ScoringFiles/PGS000331.txt.gz
PGS003327
(ExPRSweb_Insomnia_1200_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Insomnia insomnia 6,214,923
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003327/ScoringFiles/PGS003327.txt.gz
PGS004846
(tg_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Triglycerides triglyceride measurement 6,248,300
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004846/ScoringFiles/PGS004846.txt.gz
PGS003082
(ExPRSweb_SBP_93-irnt_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Systolic blood pressure systolic blood pressure 6,341,932
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003082/ScoringFiles/PGS003082.txt.gz
PGS004690
(kidney_cancer)
PGP000596 |
Hu J et al. JNCI Cancer Spectr (2024)
Kidney cancer renal carcinoma 6,351,669
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004690/ScoringFiles/PGS004690.txt.gz
PGS004693
(pancreatic_cancer)
PGP000596 |
Hu J et al. JNCI Cancer Spectr (2024)
Pancreatic cancer pancreatic carcinoma 6,351,686
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004693/ScoringFiles/PGS004693.txt.gz
PGS004692
(ovarian_cancer)
PGP000596 |
Hu J et al. JNCI Cancer Spectr (2024)
Ovarian cancer ovarian carcinoma 6,385,666
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004692/ScoringFiles/PGS004692.txt.gz
PGS000332
(PRS_BC)
PGP000100 |
Mars N et al. Nat Med (2020)
Breast cancer breast carcinoma 6,390,808
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000332/ScoringFiles/PGS000332.txt.gz
PGS000329
(PRS_CHD)
PGP000100 |
Mars N et al. Nat Med (2020)
Coronary heart disease coronary artery disease 6,423,165
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000329/ScoringFiles/PGS000329.txt.gz
PGS002243
(ldpred_t2d)
PGP000271 |
Mars N et al. Cell Genom (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 6,431,973
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002243/ScoringFiles/PGS002243.txt.gz
PGS004794
(ldl_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 6,433,913
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004794/ScoringFiles/PGS004794.txt.gz
PGS000330
(PRS_T2D)
PGP000100 |
Mars N et al. Nat Med (2020)
Type 2 diabetes (T2D) type 2 diabetes mellitus 6,437,380
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000330/ScoringFiles/PGS000330.txt.gz
PGS004842
(tc_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Total cholesterol total cholesterol measurement 6,439,132
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004842/ScoringFiles/PGS004842.txt.gz
PGS004776
(hdl_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
HDL cholesterol high density lipoprotein cholesterol measurement 6,463,324
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004776/ScoringFiles/PGS004776.txt.gz
PGS004778
(hdl_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
HDL cholesterol high density lipoprotein cholesterol measurement 6,463,324
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004778/ScoringFiles/PGS004778.txt.gz
PGS004746
(cad_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Coronary artery disease coronary artery disease 6,483,064
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004746/ScoringFiles/PGS004746.txt.gz
PGS002242
(ldpred_breastcancer)
PGP000271 |
Mars N et al. Cell Genom (2022)
Breast cancer breast carcinoma 6,494,889
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002242/ScoringFiles/PGS002242.txt.gz
PGS002241
(ldpred_prostatecancer)
PGP000271 |
Mars N et al. Cell Genom (2022)
Prostate cancer prostate carcinoma 6,497,734
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002241/ScoringFiles/PGS002241.txt.gz
PGS003052
(ExPRSweb_Smoking_20116-2_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Smoking status smoking status measurement 6,575,783
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003052/ScoringFiles/PGS003052.txt.gz
PGS002244
(ldpred_cad)
PGP000271 |
Mars N et al. Cell Genom (2022)
Coronary artery disease coronary artery disease 6,576,338
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002244/ScoringFiles/PGS002244.txt.gz
PGS004792
(ldl_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 6,580,710
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004792/ScoringFiles/PGS004792.txt.gz
PGS004868
(T2DPGS)
PGP000617 |
Yun JS et al. Cardiovasc Diabetol (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 6,580,804
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004868/ScoringFiles/PGS004868.txt.gz
PGS004818
(RA_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Rheumatoid Arthritis rheumatoid arthritis 6,580,837
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004818/ScoringFiles/PGS004818.txt.gz
PGS004820
(RA_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Rheumatoid Arthritis rheumatoid arthritis 6,580,837
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004820/ScoringFiles/PGS004820.txt.gz
PGS004838
(t2d_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 6,586,458
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004838/ScoringFiles/PGS004838.txt.gz
PGS004840
(t2d_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 6,586,458
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004840/ScoringFiles/PGS004840.txt.gz
PGS004856
(WBC_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
White blood cell count leukocyte count 6,594,323
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004856/ScoringFiles/PGS004856.txt.gz
PGS004858
(WBC_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
White blood cell count leukocyte count 6,594,323
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004858/ScoringFiles/PGS004858.txt.gz
PGS000333
(PRS_PC)
PGP000100 |
Mars N et al. Nat Med (2020)
Prostate cancer prostate carcinoma 6,606,785
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000333/ScoringFiles/PGS000333.txt.gz
PGS003407
(2_withUKB_sexMale_metaGRS.weights)
PGP000423 |
Bakker MK et al. Stroke (2023)
Intracranial aneurysm brain aneurysm,
male
6,618,190
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003407/ScoringFiles/PGS003407.txt.gz
PGS003410
(5_withUKB_sexMale_IAonly.weights)
PGP000423 |
Bakker MK et al. Stroke (2023)
Intracranial aneurysm brain aneurysm,
male
6,618,190
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003410/ScoringFiles/PGS003410.txt.gz
PGS004786
(HTN_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Hypertension hypertension 6,622,611
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004786/ScoringFiles/PGS004786.txt.gz
PGS004788
(HTN_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Hypertension hypertension 6,622,611
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004788/ScoringFiles/PGS004788.txt.gz