Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS005061
(Phe_427_21_ldpred_EURss_eurld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005061/ScoringFiles/PGS005061.txt.gz
PGS005062
(Phe_427_21_ldpred_HISss_amrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005062/ScoringFiles/PGS005062.txt.gz
PGS005063
(Phe_427_21_ldpred_METAss_afrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005063/ScoringFiles/PGS005063.txt.gz
PGS005064
(Phe_427_21_ldpred_METAss_amrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005064/ScoringFiles/PGS005064.txt.gz
PGS005065
(Phe_427_21_ldpred_METAss_eurld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005065/ScoringFiles/PGS005065.txt.gz
PGS005073
(Phe_428_1_ldpred_AFRss_afrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005073/ScoringFiles/PGS005073.txt.gz
PGS005074
(Phe_428_1_ldpred_EURss_eurld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005074/ScoringFiles/PGS005074.txt.gz
PGS005075
(Phe_428_1_ldpred_HISss_amrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005075/ScoringFiles/PGS005075.txt.gz
PGS005076
(Phe_428_1_ldpred_METAss_afrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005076/ScoringFiles/PGS005076.txt.gz
PGS005077
(Phe_428_1_ldpred_METAss_amrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005077/ScoringFiles/PGS005077.txt.gz
PGS005078
(Phe_428_1_ldpred_METAss_eurld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005078/ScoringFiles/PGS005078.txt.gz
PGS004696
(multi_anc_hg37CSx)
 PGP000602 |
Smith JL et al. Circ Genom Precis Med (2024)
 Coronary heart disease coronary artery disease 1,289,980
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004696/ScoringFiles/PGS004696.txt.gz
PGS002964
(ExPRSweb_Height_50-irnt_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Height body height 1,291,379
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002964/ScoringFiles/PGS002964.txt.gz
PGS002969
(ExPRSweb_Height_50-raw_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Height body height 1,296,068
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002969/ScoringFiles/PGS002969.txt.gz
PGS003725
(GPS_Mult)
 PGP000466 |
Patel AP et al. Nat Med (2023)
 Coronary artery disease coronary artery disease 1,296,172
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003725/ScoringFiles/PGS003725.txt.gz
PGS003726
(GPS_CADANC)
 PGP000466 |
Patel AP et al. Nat Med (2023)
 Coronary artery disease coronary artery disease 1,296,172
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003726/ScoringFiles/PGS003726.txt.gz
PGS005217
(PRS_PAD)
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Peripheral artery disease peripheral arterial disease 1,296,292
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005217/ScoringFiles/PGS005217.txt.gz
PGS005170
(iPRS_DEM)
 PGP000718 |
D'Aoust T et al. Alzheimers Dement (2025)
 All-cause dementia dementia 1,320,229
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005170/ScoringFiles/PGS005170.txt.gz
PGS004923
(T2D_metaGRS)
 PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,349,896
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004923/ScoringFiles/PGS004923.txt.gz
PGS004644
(LDL_EAS_PROSPER)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,354,681
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004644/ScoringFiles/PGS004644.txt.gz
PGS004779
(height_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Height body height 1,357,287
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004779/ScoringFiles/PGS004779.txt.gz
PGS002823
(ExPRSweb_AgeAtMenopause_ieu-a-1004_DBSLMM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menopause age at menopause 1,379,304
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002823/ScoringFiles/PGS002823.txt.gz
PGS005091
(PGS_LDP2Auto)
 PGP000684 |
Abramowitz SA et al. JAMA (2024)
 Coronary artery disease coronary artery disease 1,428,772
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005091/ScoringFiles/PGS005091.txt.gz
PGS003831
(TC_SAS_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Total cholesterol total cholesterol measurement 1,468,958
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003831/ScoringFiles/PGS003831.txt.gz
PGS003832
(TC_SAS_weighted_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Total cholesterol total cholesterol measurement 1,468,958
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003832/ScoringFiles/PGS003832.txt.gz
PGS004749
(creatinine_PRSmixPlus_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Serum creatinine serum creatinine amount 1,469,062
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004749/ScoringFiles/PGS004749.txt.gz
PGS004678
(TC_SAS_ldpred2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 Total cholesterol total cholesterol measurement 1,471,975
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004678/ScoringFiles/PGS004678.txt.gz
PGS003780
(HDL_SAS_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,473,121
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003780/ScoringFiles/PGS003780.txt.gz
PGS003781
(HDL_SAS_weighted_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,473,121
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003781/ScoringFiles/PGS003781.txt.gz
PGS004633
(HDL_SAS_ldpred2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,476,939
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004633/ScoringFiles/PGS004633.txt.gz
PGS000883
(eGFR_LDpredPRS)
 PGP000229 |
Yu Z et al. J Am Soc Nephrol (2021)
 Estimated glomerular filtration rate glomerular filtration rate 1,477,661
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000883/ScoringFiles/PGS000883.txt.gz
PGS003768
(HDL_EUR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,489,018
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003768/ScoringFiles/PGS003768.txt.gz
PGS003819
(TC_EUR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Total cholesterol total cholesterol measurement 1,490,151
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003819/ScoringFiles/PGS003819.txt.gz
PGS003785
(LDL_EUR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,490,736
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003785/ScoringFiles/PGS003785.txt.gz
PGS003802
(logTG_EUR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Log triglycerides triglyceride measurement 1,492,288
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003802/ScoringFiles/PGS003802.txt.gz
PGS003377
(eGFRldpred_PGS)
 PGP000411 |
Steinbrenner I et al. Kidney Int (2022)
 Estimated glomerular filtration rate glomerular filtration rate 1,496,254
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003377/ScoringFiles/PGS003377.txt.gz
PGS004740
(BUN_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Urea urea measurement 1,499,858
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004740/ScoringFiles/PGS004740.txt.gz
PGS004742
(BUN_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Urea urea measurement 1,499,858
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004742/ScoringFiles/PGS004742.txt.gz
PGS003814
(logTG_SAS_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Log triglycerides triglyceride measurement 1,507,338
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003814/ScoringFiles/PGS003814.txt.gz
PGS003815
(logTG_SAS_weighted_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Log triglycerides triglyceride measurement 1,507,338
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003815/ScoringFiles/PGS003815.txt.gz
PGS003797
(LDL_SAS_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,507,815
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003797/ScoringFiles/PGS003797.txt.gz
PGS003798
(LDL_SAS_weighted_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,507,815
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003798/ScoringFiles/PGS003798.txt.gz
PGS004663
(logTG_SAS_ldpred2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 Log triglycerides triglyceride measurement 1,510,317
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004663/ScoringFiles/PGS004663.txt.gz
PGS004648
(LDL_SAS_ldpred2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,511,084
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004648/ScoringFiles/PGS004648.txt.gz
PGS003355
(1MH_CAD_PRS_2015_Ldpred)
 PGP000409 |
Aragam KG et al. Nat Genet (2022)
 Coronary artery disease coronary artery disease 1,532,758
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003355/ScoringFiles/PGS003355.txt.gz
PGS004759
(depression_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Depression major depressive disorder 1,538,576
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004759/ScoringFiles/PGS004759.txt.gz
PGS004729
(Basophils_PRSmixPlus_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Basophil count basophil count 1,538,675
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004729/ScoringFiles/PGS004729.txt.gz
PGS004824
(RBC_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Red blood cell count erythrocyte count 1,542,933
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004824/ScoringFiles/PGS004824.txt.gz
PGS004768
(gout_PRSmixPlus_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Gout gout 1,580,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004768/ScoringFiles/PGS004768.txt.gz
PGS004782
(height_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Height body height 1,612,712
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004782/ScoringFiles/PGS004782.txt.gz
Showing 4801 to 4850 of 5134 rows