Publications

PGS Publication/Study ID (PGP) PGS Developed PGS Evaluated First Author Title Journal Name Publication Date Digital object identifier (doi) PubMed ID (PMID)
PGP000511 1 1 Rasooly D Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure. Nat Commun 10/07/2023 10.1038/s41467-023-39253-3 37429843
PGP000492 1 3 Thomas M Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations. Nat Commun 02/10/2023 10.1038/s41467-023-41819-0 37783704
PGP000501 26 26 Shim I Clinical utility of polygenic scores for cardiometabolic disease in Arabs. Nature Communications 18/10/2023 10.1038/s41467-023-41985-1 37852978
PGP000516 0 1 Soh P X.Y. Prostate cancer genetic risk and associated aggressive disease in men of African ancestry Nature Communications 16/11/2023 10.1038/s41467-023-43726-w 38052806
PGP000545 2 2 Middha P Polygenic risk score for ulcerative colitis predicts immune checkpoint inhibitor-mediated colitis. Nat Commun 26/03/2024 10.1038/s41467-023-44512-4 38531883
PGP000603 2 2 Loginovic P Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis. Nat Commun 28/02/2024 10.1038/s41467-024-44917-9 38418465
PGP000564 1 1 Xin J Integration of pathologic characteristics, genetic risk and lifestyle exposure for colorectal cancer survival assessment. Nat Commun 08/04/2024 10.1038/s41467-024-47204-9 38589358
PGP000595 65 65 Zhang J An ensemble penalized regression method for multi-ancestry polygenic risk prediction. Nat Commun 15/04/2024 10.1038/s41467-024-47357-7 38622117
PGP000546 60 60 Ohta R A polygenic score method boosted by non-additive models. Nat Commun 29/05/2024 10.1038/s41467-024-48654-x 38811555
PGP000618 18 18 Jermy B A unified framework for estimating country-specific cumulative incidence for 18 diseases stratified by polygenic risk. Nat Commun 12/06/2024 10.1038/s41467-024-48938-2 38866767
PGP000436 1 1 Kelemen M Evaluating the cost-effectiveness of polygenic risk score-stratified screening for abdominal aortic aneurysm. Nat Commun 14/09/2024 10.1038/s41467-024-52452-w 39277617
PGP000458 0 1 Pavelka L Age at onset as stratifier in idiopathic Parkinson's disease - effect of ageing and polygenic risk score on clinical phenotypes. NPJ Parkinsons Dis 09/08/2022 10.1038/s41531-022-00342-7 35945230
PGP000668 3 3 China Kadoorie Biobank Collaborative Group. Joint impact of polygenic risk score and lifestyles on early- and late-onset cardiovascular diseases. Nat Hum Behav 10/07/2024 10.1038/s41562-024-01923-7 38987358
PGP000333 2 3 Mishra A Stroke genetics informs drug discovery and risk prediction across ancestries Nature 30/09/2022 10.1038/s41586-022-05165-3 36180795
PGP000382 6 6 Yengo L A saturated map of common genetic variants associated with human height. Nature 12/10/2022 10.1038/s41586-022-05275-y 36224396
PGP000410 20 20 Saunders GRB Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature 07/12/2022 10.1038/s41586-022-05477-4 36477530
PGP000019 1 1 Schumacher FR Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Nat Genet 11/06/2018 10.1038/s41588-018-0142-8 29892016
PGP000061 1 1 MacGregor S Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma. Nat Genet 27/07/2018 10.1038/s41588-018-0176-y 30054594
PGP000006 5 5 Khera AV Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. Nat Genet 13/08/2018 10.1038/s41588-018-0183-z 30104762
PGP000283 2 2 Evangelou E Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet 17/09/2018 10.1038/s41588-018-0205-x 30224653
PGP000023 1 0 Mahajan A Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nat Genet 08/10/2018 10.1038/s41588-018-0241-6 30297969
PGP000170 1 0 Huyghe JR Discovery of common and rare genetic risk variants for colorectal cancer. Nat Genet 03/12/2018 10.1038/s41588-018-0286-6 30510241
PGP000086 1 1 Shrine N New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nat Genet 25/02/2019 10.1038/s41588-018-0321-7 30804560
PGP000098 1 1 Grove J Identification of common genetic risk variants for autism spectrum disorder. Nat Genet 25/02/2019 10.1038/s41588-019-0344-8 30804558
PGP000390 1 1 Wuttke M A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nat Genet 31/05/2019 10.1038/s41588-019-0407-x 31152163
PGP000063 1 1 Tin A Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nat Genet 02/10/2019 10.1038/s41588-019-0504-x 31578528
PGP000030 1 1 Klarin D Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease. Nat Genet 01/11/2019 10.1038/s41588-019-0519-3 31676865
PGP000066 1 1 Craig JE Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression. Nat Genet 20/01/2020 10.1038/s41588-019-0556-y 31959993
PGP000122 1 1 Conti DV Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet 04/01/2021 10.1038/s41588-020-00748-0 33398198
PGP000128 46 46 Sinnott-Armstrong N Genetics of 35 blood and urine biomarkers in the UK Biobank. Nat Genet 18/01/2021 10.1038/s41588-020-00757-z 33462484
PGP000182 1 2 Tadros R Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Nat Genet 25/01/2021 10.1038/s41588-020-00762-2 33495596
PGP000146 1 1 Harper AR Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity. Nat Genet 25/01/2021 10.1038/s41588-020-00764-0 33495597
PGP000068 8 8 Cai N Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Nat Genet 30/03/2020 10.1038/s41588-020-0594-5 32231276
PGP000088 5 7 Zhang H Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Nat Genet 18/05/2020 10.1038/s41588-020-0609-2 32424353
PGP000104 1 1 Koyama S Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease. Nat Genet 05/10/2020 10.1038/s41588-020-0705-3 33020668
PGP000181 1 1 Liu G Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease. Nat Genet 06/05/2021 10.1038/s41588-021-00847-6 33958783
PGP000246 3 3 Chen J The trans-ancestral genomic architecture of glycemic traits. Nat Genet 31/05/2021 10.1038/s41588-021-00852-9 34059833
PGP000211 33 34 Aly DM Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes Nat Genet 04/11/2021 10.1038/s41588-021-00948-2 34737425
PGP000296 1 1 Pirruccello JP Deep learning enables genetic analysis of the human thoracic aorta. Nat Genet 26/11/2021 10.1038/s41588-021-00962-4 34837083
PGP000302 2 2 Horowitz JE Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease. Nat Genet 03/03/2022 10.1038/s41588-021-01006-7 35241825
PGP000260 1 1 Barc J Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility. Nat Genet 24/02/2022 10.1038/s41588-021-01007-6 35210625
PGP000309 1 1 Bellenguez C New insights into the genetic etiology of Alzheimer's disease and related dementias. Nat Genet 04/04/2022 10.1038/s41588-022-01024-z 35379992
PGP000332 415 415 Weissbrod O Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores. Nat Genet 07/04/2022 10.1038/s41588-022-01036-9 35393596
PGP000268 1 1 Tcheandjieu C High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease. Nat Genet 30/05/2022 10.1038/s41588-022-01070-7 35637384
PGP000341 1 1 Vujkovic M A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation. Nat Genet 02/06/2022 10.1038/s41588-022-01078-z 35654975
PGP000357 1 1 Ishigaki K Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis. Nat Genet 04/11/2022 10.1038/s41588-022-01213-w 36333501
PGP000491 1 0 Fernandez-Rozadilla C Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries. Nat Genet 20/12/2022 10.1038/s41588-022-01222-9 36539618
PGP000409 2 2 Aragam KG Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants. Nat Genet 06/12/2022 10.1038/s41588-022-01233-6 36474045
PGP000392 1 1 Miyazawa K Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction. Nat Genet 19/01/2023 10.1038/s41588-022-01284-9 36653681
PGP000398 1 1 Ghouse J Genome-wide meta-analysis identifies 93 risk loci and enables risk prediction equivalent to monogenic forms of venous thromboembolism. Nat Genet 19/01/2023 10.1038/s41588-022-01286-7 36658437
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