Publications

PGS Publication/Study ID (PGP) PGS Developed PGS Evaluated First Author Title Journal Name Publication Date Digital object identifier (doi) PubMed ID (PMID)
PGP000023 1 0 Mahajan A Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nat Genet 08/10/2018 10.1038/s41588-018-0241-6 30297969
PGP000594 1 1 Ghouse J Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis. Nat Genet 17/04/2024 10.1038/s41588-024-01720-y 38632349
PGP000712 1 1 Roselli C Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases. Nat Genet 06/03/2025 10.1038/s41588-024-02072-3 40050429
PGP000006 5 5 Khera AV Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. Nat Genet 13/08/2018 10.1038/s41588-018-0183-z 30104762
PGP000128 46 46 Sinnott-Armstrong N Genetics of 35 blood and urine biomarkers in the UK Biobank. Nat Genet 18/01/2021 10.1038/s41588-020-00757-z 33462484
PGP000268 1 1 Tcheandjieu C High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease. Nat Genet 30/05/2022 10.1038/s41588-022-01070-7 35637384
PGP000383 1 1 Solé-Navais P Genetic effects on the timing of parturition and links to fetal birth weight. Nat Genet 03/04/2023 10.1038/s41588-023-01343-9 37012456
PGP000672 6 6 Jurgens SJ Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience. Nat Genet 21/11/2024 10.1038/s41588-024-01975-5 39572784
PGP000302 2 2 Horowitz JE Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease. Nat Genet 03/03/2022 10.1038/s41588-021-01006-7 35241825
PGP000019 1 1 Schumacher FR Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Nat Genet 11/06/2018 10.1038/s41588-018-0142-8 29892016
PGP000664 1 1 Park S Multivariate genomic analysis of 5 million people elucidates the genetic architecture of shared components of the metabolic syndrome. Nat Genet 30/09/2024 10.1038/s41588-024-01933-1 39349817
PGP000182 1 2 Tadros R Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Nat Genet 25/01/2021 10.1038/s41588-020-00762-2 33495596
PGP000489 82 82 Zhang H A new method for multiancestry polygenic prediction improves performance across diverse populations. Nat Genet 25/09/2023 10.1038/s41588-023-01501-z 37749244
PGP000640 1 1 Purdue MP Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions. Nat Genet 26/04/2024 10.1038/s41588-024-01725-7 38671320
PGP000692 4 4 Hoffmann TJ Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves prediction across ancestry groups. Nat Genet 10/02/2025 10.1038/s41588-024-02068-z 39930085
PGP000642 2 2 Zheng SL Evaluation of polygenic scores for hypertrophic cardiomyopathy in the general population and across clinical settings. Nat Genet 18/02/2025 10.1038/s41588-025-02094-5 39966645
PGP000126 1 1 Pirruccello JP Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy. Nat Commun 07/05/2020 10.1038/s41467-020-15823-7 32382064
PGP000434 1 1 Khurshid S Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass. Nat Commun 21/03/2023 10.1038/s41467-023-37173-w 36944631
PGP000429 2 2 Seviiri M A multi-phenotype analysis reveals 19 susceptibility loci for basal cell carcinoma and 15 for squamous cell carcinoma. Nat Commun 10/12/2022 10.1038/s41467-022-35345-8 36496446
PGP000102 1 3 Mars N The role of polygenic risk and susceptibility genes in breast cancer over the course of life Nat Commun 14/12/2020 10.1038/s41467-020-19966-5 33318493
PGP000101 1 1 Zhang Q Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture. Nat Commun 23/09/2020 10.1038/s41467-020-18534-1 32968074
PGP000050 16 16 Graff RE Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts. Nat Commun 12/02/2021 10.1038/s41467-021-21288-z 33579919
PGP000511 1 1 Rasooly D Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure. Nat Commun 10/07/2023 10.1038/s41467-023-39253-3 37429843
PGP000206 1 1 Teumer A Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Nat Commun 11/09/2019 10.1038/s41467-019-11576-0 31511532
PGP000546 60 60 Ohta R A polygenic score method boosted by non-additive models. Nat Commun 29/05/2024 10.1038/s41467-024-48654-x 38811555
PGP000436 1 1 Kelemen M Evaluating the cost-effectiveness of polygenic risk score-stratified screening for abdominal aortic aneurysm. Nat Commun 14/09/2024 10.1038/s41467-024-52452-w 39277617
PGP000201 3 3 Pazoki R Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes. Nat Commun 10/05/2021 10.1038/s41467-021-22338-2 33972514
PGP000320 1 1 He YQ A polygenic risk score for nasopharyngeal carcinoma shows potential for risk stratification and personalized screening. Nat Commun 12/04/2022 10.1038/s41467-022-29570-4 35414057
PGP000231 1 1 de Rojas I Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nat Commun 07/06/2021 10.1038/s41467-021-22491-8 34099642
PGP000405 18 18 Kim YJ The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians. Nat Commun 04/11/2022 10.1038/s41467-022-34163-2 36333282
PGP000629 1 1 Saw J Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction. Nat Commun 04/09/2020 10.1038/s41467-020-17558-x 32887874
PGP000046 3 3 Kuchenbaecker K The transferability of lipid loci across African, Asian and European cohorts. Nat Commun 24/09/2019 10.1038/s41467-019-12026-7 31551420
PGP000171 0 2 Fahed AC Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions. Nat Commun 20/08/2020 10.1038/s41467-020-17374-3 32820175
PGP000531 4 4 Kurniansyah N A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood. Nat Commun 21/06/2022 10.1038/s41467-022-31080-2 35729114
PGP000160 1 1 Wang YF Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups. Nat Commun 03/02/2021 10.1038/s41467-021-21049-y 33536424
PGP000545 2 2 Middha P Polygenic risk score for ulcerative colitis predicts immune checkpoint inhibitor-mediated colitis. Nat Commun 26/03/2024 10.1038/s41467-023-44512-4 38531883
PGP000492 1 3 Thomas M Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations. Nat Commun 02/10/2023 10.1038/s41467-023-41819-0 37783704
PGP000314 1 1 Pujol-Gualdo N Advancing our understanding of genetic risk factors and potential personalized strategies for pelvic organ prolapse. Nat Commun 23/06/2022 10.1038/s41467-022-31188-5 35739095
PGP000186 16 32 Kachuri L Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction. Nat Commun 27/11/2020 10.1038/s41467-020-19600-4 33247094
PGP000618 18 18 Jermy B A unified framework for estimating country-specific cumulative incidence for 18 diseases stratified by polygenic risk. Nat Commun 12/06/2024 10.1038/s41467-024-48938-2 38866767
PGP000149 1 1 Huynh-Le MP Polygenic hazard score is associated with prostate cancer in multi-ethnic populations. Nat Commun 23/02/2021 10.1038/s41467-021-21287-0 33623038
PGP000147 0 11 Thareja G Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Nat Commun 23/02/2021 10.1038/s41467-021-21381-3 33623009
PGP000027 1 2 Abraham G Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke. Nat Commun 20/12/2019 10.1038/s41467-019-13848-1 31862893
PGP000603 2 2 Loginovic P Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis. Nat Commun 28/02/2024 10.1038/s41467-024-44917-9 38418465
PGP000427 1 1 Krohn L Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects. Nat Commun 05/12/2022 10.1038/s41467-022-34732-5 36470867
PGP000510 8 2 Kurniansyah N Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups. Nat Commun 02/06/2023 10.1038/s41467-023-38990-9 37268629
PGP000236 2 2 Ntalla I Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. Nat Commun 21/05/2020 10.1038/s41467-020-15706-x 32439900
PGP000164 3 3 Khan Z Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade. Nat Commun 07/06/2021 10.1038/s41467-021-23661-4 34099659
PGP000138 3 3 Fontanillas P Disease risk scores for skin cancers. Nat Commun 08/01/2021 10.1038/s41467-020-20246-5 33420020
PGP000564 1 1 Xin J Integration of pathologic characteristics, genetic risk and lifestyle exposure for colorectal cancer survival assessment. Nat Commun 08/04/2024 10.1038/s41467-024-47204-9 38589358
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