Latest Release - Oct. 6, 2025

New Publications (11)

PGS
Publication/Study
ID (PGP)
PGS
Developed
PGS
Evaluated
First Author Title Journal Name Publication
Date
Digital object identifier (doi) PubMed ID
(PMID)
PGP000761 1 1 Yuan S Cross-population GWAS and proteomics improve risk prediction and reveal mechanisms in atrial fibrillation. Nat Commun 11/07/2025 10.1038/s41467-025-61720-2 40645996
PGP000741 5 5 Tanha HM Polygenic risk scores for prostate cancer: Comparative evaluations in UK and Australian cohorts. HGG Adv 07/07/2025 10.1016/j.xhgg.2025.100477 40629691
PGP000739 4 4 Arehart CH Modeling the genomic architecture of adiposity and anthropometrics across the lifespan. Nat Commun 13/08/2025 10.1038/s41467-025-62730-w 40796553
PGP000766 7 7 Türkmen D Polygenic scores for cardiovascular risk factors improve estimation of clinical outcomes in CCB treatment compared to pharmacogenetic variants alone. Pharmacogenomics J 17/04/2024 10.1038/s41397-024-00333-2 38632276
PGP000767 0 2 Beck JJ Breast Cancer Polygenic Risk Score Validation and Effects of Variable Imputation. Cancers (Basel) 20/04/2024 10.3390/cancers16081578 38672660
PGP000768 1 1 Marston NA Endothelial cell-related genetic variants identify LDL cholesterol-sensitive individuals who derive greater benefit from aggressive lipid lowering. Nat Med 26/02/2025 10.1038/s41591-025-03533-w 40011692
PGP000764 0 1 Yang PK Type 1 Diabetes Genetic Risk in 109,954 Veterans With Adult-Onset Diabetes: The Million Veteran Program (MVP). Diabetes Care 01/06/2024 10.2337/dc23-1927 38608262
PGP000762 1 1 Irvin MR Polygenic Risk for Type 2 Diabetes in African Americans. Diabetes 01/06/2024 10.2337/db23-0232 38470993
PGP000742 6 6 Guo B G Polygenic risk score for type 2 diabetes shows context-dependent effects across populations. Nat Commun 25/06/2025 10.1038/s41467-025-63546-4 41034193
PGP000763 0 2 Zou RS Polygenic Scores and Preclinical Cardiovascular Disease in Individuals With HIV: Insights From the REPRIEVE Trial. J Am Heart Assoc 27/03/2024 10.1161/jaha.123.033413 38533953
PGP000765 0 1 Gandhi SE Motor Complications in Parkinson's Disease: Results from 3343 Patients Followed for up to 12 Years. Mov Disord Clin Pract 08/04/2024 10.1002/mdc3.14044 38587023

New Polygenic Scores (25)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS005232
(F1_Birth_Size)
PGP000739 |
Arehart CH et al. Nat Commun (2025)
Birth size birth weight 710,799
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005232/ScoringFiles/PGS005232.txt.gz
PGS005233
(F2_Abdominal_Size)
PGP000739 |
Arehart CH et al. Nat Commun (2025)
Abdominal size body fat distribution 710,487
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005233/ScoringFiles/PGS005233.txt.gz
PGS005234
(F3_Body_Size_and_Adipose_Distribution)
PGP000739 |
Arehart CH et al. Nat Commun (2025)
Body size and adipose distribution body weight,
body fat distribution
709,193
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005234/ScoringFiles/PGS005234.txt.gz
PGS005235
(F4_Adiposity)
PGP000739 |
Arehart CH et al. Nat Commun (2025)
Adiposity obesity 709,828
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005235/ScoringFiles/PGS005235.txt.gz
PGS005237
(SCT)
PGP000741 |
Tanha HM et al. HGG Adv (2025)
Prostate carcinoma prostate carcinoma 517,551
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005237/ScoringFiles/PGS005237.txt.gz
PGS005238
(LDpred2)
PGP000741 |
Tanha HM et al. HGG Adv (2025)
Prostate carcinoma prostate carcinoma 964,607
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005238/ScoringFiles/PGS005238.txt.gz
PGS005239
(PRS-CS)
PGP000741 |
Tanha HM et al. HGG Adv (2025)
Prostate carcinoma prostate carcinoma 943,048
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005239/ScoringFiles/PGS005239.txt.gz
PGS005240
(SBayesR)
PGP000741 |
Tanha HM et al. HGG Adv (2025)
Prostate carcinoma prostate carcinoma 904,103
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005240/ScoringFiles/PGS005240.txt.gz
PGS005241
(SBayesRC)
PGP000741 |
Tanha HM et al. HGG Adv (2025)
Prostate carcinoma prostate carcinoma 3,802,635
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005241/ScoringFiles/PGS005241.txt.gz
PGS005242
(T2D_PRS_PRS_CSx_META_T)
PGP000742 |
Guo B G et al. Nat Commun (2025)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,257,036
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005242/ScoringFiles/PGS005242.txt.gz
PGS005243
(T2D_PRS_PRS_CSx_META_F_AFR)
PGP000742 |
Guo B G et al. Nat Commun (2025)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,183,017
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005243/ScoringFiles/PGS005243.txt.gz
PGS005244
(T2D_PRS_PRS_CSx_META_F_AMR)
PGP000742 |
Guo B G et al. Nat Commun (2025)
Type 2 diabetes (T2D) type 2 diabetes mellitus 960,470
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005244/ScoringFiles/PGS005244.txt.gz
PGS005245
(T2D_PRS_PRS_CSx_META_F_EAS)
PGP000742 |
Guo B G et al. Nat Commun (2025)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,021,829
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005245/ScoringFiles/PGS005245.txt.gz
PGS005246
(T2D_PRS_PRS_CSx_META_F_EUR)
PGP000742 |
Guo B G et al. Nat Commun (2025)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,111,848
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005246/ScoringFiles/PGS005246.txt.gz
PGS005247
(T2D_PRS_PRS_CSx_META_F_SAS)
PGP000742 |
Guo B G et al. Nat Commun (2025)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,126,657
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005247/ScoringFiles/PGS005247.txt.gz
PGS005313
(AF_PGS_YuanS)
PGP000761 |
Yuan S et al. Nat Commun (2025)
Atrial fibrillation atrial fibrillation 1,271,239
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005313/ScoringFiles/PGS005313.txt.gz
PGS005314
(T2D_PRS_AA)
PGP000762 |
Irvin MR et al. Diabetes (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,181,614
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005314/ScoringFiles/PGS005314.txt.gz
PGS005315
(ALM_PRS)
PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
Appendicular lean mass lean body mass 630
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005315/ScoringFiles/PGS005315.txt.gz
PGS005316
(BFM_PRS)
PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
Body fat mass body fat distribution 403
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005316/ScoringFiles/PGS005316.txt.gz
PGS005317
(DBP_PRS)
PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
Diastolic blood pressure diastolic blood pressure 297
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005317/ScoringFiles/PGS005317.txt.gz
PGS005318
(eGFR_PRS)
PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
eGFR glomerular filtration rate 49
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005318/ScoringFiles/PGS005318.txt.gz
PGS005319
(HF_PRS)
PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
Heart failure heart failure 12
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005319/ScoringFiles/PGS005319.txt.gz
PGS005320
(LPA_PRS)
PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
Lipoprotein (a) lipoprotein A measurement 36
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005320/ScoringFiles/PGS005320.txt.gz
PGS005321
(SBP_PRS)
PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
Systolic blood pressure systolic blood pressure 240
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005321/ScoringFiles/PGS005321.txt.gz
PGS005322
(PRS_EC)
PGP000768 |
Marston NA et al. Nat Med (2025)
Coronary artery disease (Endothelial cell-related) coronary artery disease 36
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005322/ScoringFiles/PGS005322.txt.gz