|
PGS Publication/Study ID (PGP) |
PGS Developed |
PGS Evaluated |
First Author | Title | Journal Name |
Publication Date |
Digital object identifier (doi) |
PubMed ID (PMID) |
|---|---|---|---|---|---|---|---|---|
| PGP000747 | 4 | 4 | Kany S | Multitrait analyses identify genetic variants associated with aortic valve function and aortic stenosis risk. | Nat Genet | 19/12/2025 | 10.1038/s41588-025-02397-7 | 41419685 |
| PGP000748 | 17 | 17 | White SL | Global multi-ancestry genetic study elucidates genes and biological pathways associated with thyroid cancer and benign thyroid diseases | medRxivPre | 16/05/2025 | 10.1101/2025.05.15.25327513 | — |
| PGP000760 | 6 | 6 | Saklatvala JR | Genetic liability to psoriasis predicts severe disease outcomes. | Genome Med | 17/12/2025 | 10.1186/s13073-025-01561-2 | 41408349 |
| PGP000777 | 1 | 1 | Aliyu U | Genome-wide association study and polygenic score assessment of insulin resistance. | Front Endocrinol (Lausanne) | 13/06/2024 | 10.3389/fendo.2024.1384103 | 38938516 |
| PGP000745 | 1 | 1 | Small AM | Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction. | Nat Genet | 19/12/2025 | 10.1038/s41588-025-02417-6 | 41419686 |
| PGP000778 | 1 | 1 | Bugiga AVG | The interaction between polygenic risk score and trauma affects the likelihood of post-traumatic stress disorder in female victims of sexual assault. | Braz J Psychiatry | 11/03/2024 | 10.47626/1516-4446-2023-3335 | 38467473 |
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS005252 (IAVGC_AS_PRS) |
PGP000745 | Small AM et al. Nat Genet (2025) |
Aortic stenosis | aortic stenosis | 1,119,377 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005252/ScoringFiles/PGS005252.txt.gz |
| PGS005254 (aortic_stenosis) |
PGP000747 | Kany S et al. Nat Genet (2025) |
Aortic stenosis | aortic stenosis | 1,110,912 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005254/ScoringFiles/PGS005254.txt.gz |
| PGS005255 (mean_gradient) |
PGP000747 | Kany S et al. Nat Genet (2025) |
Mean pressure gradient | aortic stenosis, aortic measurement |
1,111,632 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005255/ScoringFiles/PGS005255.txt.gz |
| PGS005256 (peak_velocity) |
PGP000747 | Kany S et al. Nat Genet (2025) |
Peak aortic velocity | aortic stenosis, aortic measurement |
1,111,632 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005256/ScoringFiles/PGS005256.txt.gz |
| PGS005257 (aortic_valve_area) |
PGP000747 | Kany S et al. Nat Genet (2025) |
Aortic valve area | aortic measurement | 1,111,632 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005257/ScoringFiles/PGS005257.txt.gz |
| PGS005258 (thyroid_cancer_mixed_pt) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Thyroid carcenoma | thyroid carcinoma | 84 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005258/ScoringFiles/PGS005258.txt.gz |
| PGS005259 (thyroid_cancer_mixed_prscs) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Thyroid carcenoma | thyroid carcinoma | 1,085,173 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005259/ScoringFiles/PGS005259.txt.gz |
| PGS005260 (thyroid_cancer_eur_prscs) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Thyroid carcenoma | thyroid carcinoma | 1,085,170 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005260/ScoringFiles/PGS005260.txt.gz |
| PGS005261 (benign_nodular_goiter_mixed_pt) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Benign nodular goiter | benign, nodular goiter |
110 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005261/ScoringFiles/PGS005261.txt.gz |
| PGS005262 (benign_nodular_goiter_mixed_prscs) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Benign nodular goiter | benign, nodular goiter |
1,085,173 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005262/ScoringFiles/PGS005262.txt.gz |
| PGS005263 (benign_nodular_goiter_eur_prscs) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Benign nodular goiter | benign, nodular goiter |
1,085,170 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005263/ScoringFiles/PGS005263.txt.gz |
| PGS005264 (graves_disease_mixed_pt) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Graves' disease | Graves disease | 112 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005264/ScoringFiles/PGS005264.txt.gz |
| PGS005265 (graves_disease_mixed_prscs) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Graves' disease | Graves disease | 1,085,173 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005265/ScoringFiles/PGS005265.txt.gz |
| PGS005266 (graves_disease_eur_prscs) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Graves' disease | Graves disease | 1,085,170 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005266/ScoringFiles/PGS005266.txt.gz |
| PGS005267 (hypothyroidism_mixed_pt) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Hypothyroidism | hypothyroidism | 439 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005267/ScoringFiles/PGS005267.txt.gz |
| PGS005268 (hypothyroidism_mixed_prscs) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Hypothyroidism | hypothyroidism | 1,085,173 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005268/ScoringFiles/PGS005268.txt.gz |
| PGS005269 (hypothyroidism_eur_prscs) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Hypothyroidism | hypothyroidism | 1,085,170 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005269/ScoringFiles/PGS005269.txt.gz |
| PGS005270 (lymphocytic_thyroiditis_mixed_pt) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Lymphocytic thyroiditis | Hashimoto's thyroiditis | 55 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005270/ScoringFiles/PGS005270.txt.gz |
| PGS005271 (lymphocytic_thyroiditis_mixed_prscs) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Lymphocytic thyroiditis | Hashimoto's thyroiditis | 1,085,156 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005271/ScoringFiles/PGS005271.txt.gz |
| PGS005272 (lymphocytic_thyroiditis_eur_prscs) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Lymphocytic thyroiditis | Hashimoto's thyroiditis | 1,085,142 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005272/ScoringFiles/PGS005272.txt.gz |
| PGS005273 (tc_vs_bng_mixed_prscs) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Thyroid carcenoma vs benign nodular goiter | benign, thyroid carcinoma, nodular goiter |
1,085,164 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005273/ScoringFiles/PGS005273.txt.gz |
| PGS005274 (tc_vs_bng_eur_prscs) |
PGP000748 | White SL et al. medRxiv (2025) |Pre |
Thyroid carcenoma vs benign nodular goiter | benign, thyroid carcinoma, nodular goiter |
1,084,965 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005274/ScoringFiles/PGS005274.txt.gz |
| PGS005307 (GWS) |
PGP000760 | Saklatvala JR et al. Genome Med (2025) |
Psoriasis | psoriasis | 64 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005307/ScoringFiles/PGS005307.txt.gz |
| PGS005308 (GWS-noHLA) |
PGP000760 | Saklatvala JR et al. Genome Med (2025) |
Psoriasis | psoriasis | 64 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005308/ScoringFiles/PGS005308.txt.gz |
| PGS005309 (Full) |
PGP000760 | Saklatvala JR et al. Genome Med (2025) |
Psoriasis | psoriasis | 513,461 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005309/ScoringFiles/PGS005309.txt.gz |
| PGS005310 (Full-noHLA) |
PGP000760 | Saklatvala JR et al. Genome Med (2025) |
Psoriasis | psoriasis | 513,460 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005310/ScoringFiles/PGS005310.txt.gz |
| PGS005311 (Full_subset) |
PGP000760 | Saklatvala JR et al. Genome Med (2025) |
Psoriasis | psoriasis | 487,311 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005311/ScoringFiles/PGS005311.txt.gz |
| PGS005312 (Full-noHLA_subset) |
PGP000760 | Saklatvala JR et al. Genome Med (2025) |
Psoriasis | psoriasis | 487,310 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005312/ScoringFiles/PGS005312.txt.gz |
| PGS005392 (Q-PGS4_r0.2_p5e4) |
PGP000777 | Aliyu U et al. Front Endocrinol (Lausanne) (2024) |
HOMA2-IR | HOMA-IR | 1,414 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005392/ScoringFiles/PGS005392.txt.gz |
| PGS005393 (PGS_SEXUAL_ASSAULT_PTSD) |
PGP000778 | Bugiga AVG et al. Braz J Psychiatry (2024) |
Post-traumatic stress disorder | post-traumatic stress disorder | 53,705 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005393/ScoringFiles/PGS005393.txt.gz |