PGS Publication: PGP000195

Publication Information (EuropePMC)
Title Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.
PubMed ID 29083406(Europe PMC)
doi 10.1038/ng.3985
Publication Date Oct. 30, 2017
Journal Nat Genet
Author(s) Ferreira MA, Vonk JM, Baurecht H, Marenholz I, Tian C, Hoffman JD, Helmer Q, Tillander A, Ullemar V, van Dongen J, Lu Y, Rüschendorf F, Esparza-Gordillo J, Medway CW, Mountjoy E, Burrows K, Hummel O, Grosche S, Brumpton BM, Witte JS, Hottenga JJ, Willemsen G, Zheng J, Rodríguez E, Hotze M, Franke A, Revez JA, Beesley J, Matheson MC, Dharmage SC, Bain LM, Fritsche LG, Gabrielsen ME, Balliu B, 23andMe Research Team, AAGC collaborators, BIOS consortium, LifeLines Cohort Study, Nielsen JB, Zhou W, Hveem K, Langhammer A, Holmen OL, Løset M, Abecasis GR, Willer CJ, Arnold A, Homuth G, Schmidt CO, Thompson PJ, Martin NG, Duffy DL, Novak N, Schulz H, Karrasch S, Gieger C, Strauch K, Melles RB, Hinds DA, Hübner N, Weidinger S, Magnusson PKE, Jansen R, Jorgenson E, Lee YA, Boomsma DI, Almqvist C, Karlsson R, Koppelman GH, Paternoster L.
Released in PGS Catalog: July 2, 2021

Associated Polygenic Score(s)

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PGS Developed By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution PGS Scoring File (FTP Link)
PGS000810
(wGRS136_Allergy)
PGP000195 |
Ferreira MA et al. Nat Genet (2017)
Allergic disease (asthma, hay fever or eczema) allergy 136
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https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000810/ScoringFiles/PGS000810.txt.gz

Performance Metrics

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PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
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Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information