PGS Publication: PGP000343

Publication Information (EuropePMC)
Title Association between genetic risk of high SBP and hypertension control: the CoLaus|PsyColaus study.
PubMed ID 35703291(Europe PMC)
doi 10.1097/hjh.0000000000003158
Publication Date June 10, 2022
Journal J Hypertens
Author(s) Marques-Vidal P, Chekanova V, Vaucher J.
Released in PGS Catalog: July 21, 2022

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Multi-ancestry (excluding European)
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East Asian
South Asian
Additional Asian Ancestries
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Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported

PGS Developed By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002734
(GRS_SBP_362)
 PGP000343 |
Marques-Vidal P et al. J Hypertens (2022)
 Systolic blood pressure systolic blood pressure 362
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002734/ScoringFiles/PGS002734.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM014825 PGS002734
(GRS_SBP_362)
 PSS009904|
Ancestry Not Reported|
2,944 individuals
 PGP000343 |
Marques-Vidal P et al. J Hypertens (2022)
 Reported Trait: Systolic blood pressure levels untreated for hypertension — — Correlation: 0.062 [0.026, 0.098] — —
PPM014826 PGS002734
(GRS_SBP_362)
 PSS009905|
Ancestry Not Reported|
2,541 individuals
 PGP000343 |
Marques-Vidal P et al. J Hypertens (2022)
 Reported Trait: Systolic blood pressure levels untreated for hypertension — — Correlation: 0.783 [0.488, 1.079] — —
PPM014827 PGS002734
(GRS_SBP_362)
 PSS009906|
Ancestry Not Reported|
1,920 individuals
 PGP000343 |
Marques-Vidal P et al. J Hypertens (2022)
 Reported Trait: Systolic blood pressure levels untreated for hypertension — — Correlation: 0.05 [0.003, 0.096] — —
PPM014828 PGS002734
(GRS_SBP_362)
 PSS009903|
Ancestry Not Reported|
4,333 individuals
 PGP000343 |
Marques-Vidal P et al. J Hypertens (2022)
 Reported Trait: Systolic blood pressure levels treated for hypertension — — Correlation: 0.054 [-0.006, 0.113] — —
PPM014829 PGS002734
(GRS_SBP_362)
 PSS009904|
Ancestry Not Reported|
2,944 individuals
 PGP000343 |
Marques-Vidal P et al. J Hypertens (2022)
 Reported Trait: Systolic blood pressure levels treated for hypertension — — Correlation: 0.045 [-0.011, 0.102] — —
PPM014830 PGS002734
(GRS_SBP_362)
 PSS009905|
Ancestry Not Reported|
2,541 individuals
 PGP000343 |
Marques-Vidal P et al. J Hypertens (2022)
 Reported Trait: Systolic blood pressure levels treated for hypertension — — Correlation: 0.05 [-0.012, 0.111] — —
PPM014831 PGS002734
(GRS_SBP_362)
 PSS009906|
Ancestry Not Reported|
1,920 individuals
 PGP000343 |
Marques-Vidal P et al. J Hypertens (2022)
 Reported Trait: Systolic blood pressure levels treated for hypertension — — Correlation: 0.066 [-0.001, 0.133] — —
PPM014824 PGS002734
(GRS_SBP_362)
 PSS009903|
Ancestry Not Reported|
4,333 individuals
 PGP000343 |
Marques-Vidal P et al. J Hypertens (2022)
 Reported Trait: Systolic blood pressure levels untreated for hypertension — — Correlation: 0.086 [0.058, 0.115] — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009903 — — 4,333 individuals,
46.0 % Male samples
 Mean = 52.0 years Not reported — CoLaus CoLaus|PsyCoLaus
PSS009904 — — 2,944 individuals,
44.0 % Male samples
 Mean = 56.0 years Not reported — CoLaus CoLaus|PsyCoLaus
PSS009905 — — 2,541 individuals,
42.0 % Male samples
 Mean = 61.0 years Not reported — CoLaus CoLaus|PsyCoLaus
PSS009906 — — 1,920 individuals,
41.0 % Male samples
 Mean = 63.0 years Not reported — CoLaus CoLaus|PsyCoLaus