PGS Publication: PGP000813

Publication Information (EuropePMC)
Title Risk prediction and interaction analysis using polygenic risk score of type 2 diabetes in a Korean population.
PubMed ID 38514700(Europe PMC)
doi 10.1038/s41598-024-55945-2
Publication Date March 21, 2024
Journal Sci Rep
Author(s) Song M, Kwak SH, Kim J.
Released in PGS Catalog: June 17, 2026

Associated Polygenic Score(s)

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Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
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Additional Diverse Ancestries
Not Reported

PGS Developed By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS012578
(PRS1004_t2d)
 PGP000813 |
Song M et al. Sci Rep (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,004
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012578/ScoringFiles/PGS012578.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM030729 PGS012578
(PRS1004_t2d)
 PSS012269|
East Asian Ancestry|
41,387 individuals
 PGP000813 |
Song M et al. Sci Rep (2024)
 Reported Trait: Type 2 diabetes OR: 1.964 [1.901, 2.028] — — age, sex, and BMI —
PPM030730 PGS012578
(PRS1004_t2d)
 PSS012269|
East Asian Ancestry|
41,387 individuals
 PGP000813 |
Song M et al. Sci Rep (2024)
 Reported Trait: Type 2 diabetes in abdominal obesity OR: 1.758 [1.665, 1.855] — — age, sex, and BMI —
PPM030731 PGS012578
(PRS1004_t2d)
 PSS012269|
East Asian Ancestry|
41,387 individuals
 PGP000813 |
Song M et al. Sci Rep (2024)
 Reported Trait: Type 2 diabetes without abdominal obesity OR: 2.083 [2.001, 2.168] — — age, sex, and BMI —
PPM030732 PGS012578
(PRS1004_t2d)
 PSS012269|
East Asian Ancestry|
41,387 individuals
 PGP000813 |
Song M et al. Sci Rep (2024)
 Reported Trait: Type 2 diabetes x waist circumference interaction OR: 0.991 [0.987, 0.995] — — age, sex, BMI, residence area —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS012269 — —
[
  • 5,684 cases
  • , 35,703 controls
]
 — East Asian
(Japanese)		 — HEXA —