PGS Publication: PGP000840

Publication Information (EuropePMC)
Title Genome-wide association study and trans-ethnic meta-analysis identify novel susceptibility loci for type 2 diabetes mellitus.
PubMed ID 38685053(Europe PMC)
doi 10.1186/s12920-024-01855-1
Publication Date April 29, 2024
Journal BMC Med Genomics
Author(s) Elashi AA, Toor SM, Umlai UI, Al-Sarraj YA, Taheri S, Suhre K, Abou-Samra AB, Albagha OME.
Released in PGS Catalog: Aug. 26, 2026

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Additional Diverse Ancestries
Not Reported

External PGS Evaluated By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000036
(gePS_T2D)
 PGP000023 |
Mahajan A et al. Nat Genet (2018)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 171,249
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000036/ScoringFiles/PGS000036.txt.gz
PGS000804
(GRS582_T2Dmulti)
 PGP000193 |
Polfus LM et al. HGG Adv (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000804/ScoringFiles/PGS000804.txt.gz - Check Terms/Licenses

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM038137 PGS000036
(gePS_T2D)
 PSS013832|
Greater Middle Eastern Ancestry|
4,938 individuals
 PGP000840 |
Elashi AA et al. BMC Med Genomics (2024)
|Ext.		 Reported Trait: Type 2 diabetes — AUROC: 0.83 — age, gender and BMI —
PPM038138 PGS000804
(GRS582_T2Dmulti)
 PSS013832|
Greater Middle Eastern Ancestry|
4,938 individuals
 PGP000840 |
Elashi AA et al. BMC Med Genomics (2024)
|Ext.		 Reported Trait: Type 2 diabetes — AUROC: 0.83 — age, gender and BMI —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013832 — —
[
  • 2,469 cases
  • , 2,469 controls
]
,
41.0 % Male samples
 — Greater Middle Eastern (Middle Eastern, North African or Persian)
(Qatari)		 — QBB —