PGS Publication: PGP000863

Publication Information (EuropePMC)
Title Polygenic risk score predicting susceptibility and outcome of benign prostatic hyperplasia in the Han Chinese.
PubMed ID 38778357(Europe PMC)
doi 10.1186/s40246-024-00619-3
Publication Date May 22, 2024
Journal Hum Genomics
Author(s) Hung SC, Chang LW, Hsiao TH, Lin GC, Wang SS, Li JR, Chen IC.
Released in PGS Catalog: Oct. 23, 2026

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported

External PGS Evaluated By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001865
(portability-PLR_600)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hyperplasia of prostate benign prostatic hyperplasia 1,712
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001865/ScoringFiles/PGS001865.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM038304 PGS001865
(portability-PLR_600)
 PSS013910|
East Asian Ancestry|
12,474 individuals
 PGP000863 |
Hung SC et al. Hum Genomics (2024)
|Ext.		 Reported Trait: Benign prostatic hyperplasia — — Hazard ratio (HR, high vs low quartile): 1.51 [1.274, 1.783] PSA level —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013910 — —
[
  • 6,237 cases
  • , 6,237 controls
]
,
100.0 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —