Polygenic Score (PGS) ID: PGS001984

Predicted Trait
Reported Trait Whole body water mass
Mapped Trait(s) whole body water mass (EFO_0009805)
Additional Trait Information physical measures
Released in PGS Catalog: Jan. 10, 2022
Download Score FTP directory
Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name portability-PLR_log_water_mass
Development Method
Name Penalized regression (bigstatsr)
Parameters HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 127,910
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 37.5%
African: 25%
East Asian: 12.5%
Greater Middle Eastern: 12.5%
South Asian: 12.5%
8 Sample Sets

Development Samples

Score Development/Training
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
391,124 individuals European UK (+ Ireland) UKB

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010747 PSS009472|
European Ancestry|
19,641 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.4574 [0.4462, 0.4684] sex, age, birth date, deprivation index, 16 PCs
PPM010749 PSS008800|
European Ancestry|
6,539 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.4309 [0.4109, 0.4505] sex, age, birth date, deprivation index, 16 PCs
PPM010750 PSS008574|
Greater Middle Eastern Ancestry|
1,152 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3695 [0.3181, 0.4188] sex, age, birth date, deprivation index, 16 PCs
PPM010752 PSS008129|
East Asian Ancestry|
1,782 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3166 [0.274, 0.358] sex, age, birth date, deprivation index, 16 PCs
PPM010753 PSS007916|
African Ancestry|
2,420 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.2518 [0.2139, 0.2889] sex, age, birth date, deprivation index, 16 PCs
PPM010754 PSS009020|
African Ancestry|
3,801 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.1924 [0.1615, 0.2229] sex, age, birth date, deprivation index, 16 PCs
PPM010748 PSS009246|
European Ancestry|
4,073 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.4477 [0.4228, 0.472] sex, age, birth date, deprivation index, 16 PCs
PPM010751 PSS008352|
South Asian Ancestry|
6,185 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3881 [0.3667, 0.4091] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009246 4,073 individuals European Poland (NE Europe) UKB
PSS007916 2,420 individuals African American or Afro-Caribbean Carribean UKB
PSS008352 6,185 individuals South Asian India (South Asia) UKB
PSS009472 19,641 individuals European UK (+ Ireland) UKB
PSS009020 3,801 individuals African unspecified Nigeria (West Africa) UKB
PSS008574 1,152 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008800 6,539 individuals European Italy (South Europe) UKB
PSS008129 1,782 individuals East Asian China (East Asia) UKB