Trait: whole body water mass

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009805
Description The weight of an individual's body water, i.e. the water content of a body that is contained in the tissues, the blood, the bones and elsewhere. The percentages of body water contained in various fluid compartments add up to total body water (TBW).
Trait category
Other measurement
Mapped term Wikipedia:Body_water

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS001002
(GBE_INI23102)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Whole body water mass whole body water mass 35,046
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001002/ScoringFiles/PGS001002.txt.gz
PGS001984
(portability-PLR_log_water_mass)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Whole body water mass whole body water mass 127,910
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001984/ScoringFiles/PGS001984.txt.gz
PGS002202
(portability-ldpred2_log_water_mass)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Whole body water mass whole body water mass 966,737
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002202/ScoringFiles/PGS002202.txt.gz
PGS003540
(cont-decay-log_impedance)
PGP000457 |
Ding Y et al. Nature (2023)
Impedance of whole body whole body water mass 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003540/ScoringFiles/PGS003540.txt.gz
PGS003556
(cont-decay-log_water_mass)
PGP000457 |
Ding Y et al. Nature (2023)
Whole body water mass whole body water mass 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003556/ScoringFiles/PGS003556.txt.gz
PGS003902
(INI23102)
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Whole body water mass whole body water mass 43,166
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003902/ScoringFiles/PGS003902.txt.gz
PGS004377
(X23102.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Whole body water mass whole body water mass 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004377/ScoringFiles/PGS004377.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007773 PGS001002
(GBE_INI23102)
PSS005051|
African Ancestry|
6,305 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass — — R²: 0.59835 [0.58325, 0.61345]
Incremental R2 (full-covars): 0.01006
PGS R2 (no covariates): 0.01762 [0.01128, 0.02396]
age, sex, UKB array type, Genotype PCs —
PPM007774 PGS001002
(GBE_INI23102)
PSS005052|
East Asian Ancestry|
1,680 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass — — R²: 0.74997 [0.72945, 0.77049]
Incremental R2 (full-covars): 0.00739
PGS R2 (no covariates): 0.0184 [0.00578, 0.03102]
age, sex, UKB array type, Genotype PCs —
PPM007775 PGS001002
(GBE_INI23102)
PSS005053|
European Ancestry|
24,466 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass — — R²: 0.75696 [0.7517, 0.76221]
Incremental R2 (full-covars): 0.04635
PGS R2 (no covariates): 0.04558 [0.04052, 0.05064]
age, sex, UKB array type, Genotype PCs —
PPM007776 PGS001002
(GBE_INI23102)
PSS005054|
South Asian Ancestry|
7,649 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass — — R²: 0.6942 [0.68292, 0.70548]
Incremental R2 (full-covars): 0.03631
PGS R2 (no covariates): 0.02751 [0.02037, 0.03465]
age, sex, UKB array type, Genotype PCs —
PPM007777 PGS001002
(GBE_INI23102)
PSS005055|
European Ancestry|
66,264 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass — — R²: 0.75779 [0.75461, 0.76097]
Incremental R2 (full-covars): 0.05245
PGS R2 (no covariates): 0.05076 [0.04753, 0.05399]
age, sex, UKB array type, Genotype PCs —
PPM010747 PGS001984
(portability-PLR_log_water_mass)
PSS009472|
European Ancestry|
19,641 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.4574 [0.4462, 0.4684] sex, age, birth date, deprivation index, 16 PCs —
PPM010749 PGS001984
(portability-PLR_log_water_mass)
PSS008800|
European Ancestry|
6,539 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.4309 [0.4109, 0.4505] sex, age, birth date, deprivation index, 16 PCs —
PPM010750 PGS001984
(portability-PLR_log_water_mass)
PSS008574|
Greater Middle Eastern Ancestry|
1,152 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.3695 [0.3181, 0.4188] sex, age, birth date, deprivation index, 16 PCs —
PPM010752 PGS001984
(portability-PLR_log_water_mass)
PSS008129|
East Asian Ancestry|
1,782 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.3166 [0.274, 0.358] sex, age, birth date, deprivation index, 16 PCs —
PPM010753 PGS001984
(portability-PLR_log_water_mass)
PSS007916|
African Ancestry|
2,420 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.2518 [0.2139, 0.2889] sex, age, birth date, deprivation index, 16 PCs —
PPM010754 PGS001984
(portability-PLR_log_water_mass)
PSS009020|
African Ancestry|
3,801 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.1924 [0.1615, 0.2229] sex, age, birth date, deprivation index, 16 PCs —
PPM010748 PGS001984
(portability-PLR_log_water_mass)
PSS009246|
European Ancestry|
4,073 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.4477 [0.4228, 0.472] sex, age, birth date, deprivation index, 16 PCs —
PPM010751 PGS001984
(portability-PLR_log_water_mass)
PSS008352|
South Asian Ancestry|
6,185 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.3881 [0.3667, 0.4091] sex, age, birth date, deprivation index, 16 PCs —
PPM012463 PGS002202
(portability-ldpred2_log_water_mass)
PSS009472|
European Ancestry|
19,641 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.446 [0.4347, 0.4571] sex, age, birth date, deprivation index, 16 PCs —
PPM012464 PGS002202
(portability-ldpred2_log_water_mass)
PSS009246|
European Ancestry|
4,073 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.4481 [0.4232, 0.4724] sex, age, birth date, deprivation index, 16 PCs —
PPM012465 PGS002202
(portability-ldpred2_log_water_mass)
PSS008800|
European Ancestry|
6,539 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.4242 [0.4041, 0.4439] sex, age, birth date, deprivation index, 16 PCs —
PPM012466 PGS002202
(portability-ldpred2_log_water_mass)
PSS008574|
Greater Middle Eastern Ancestry|
1,152 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.3643 [0.3127, 0.4138] sex, age, birth date, deprivation index, 16 PCs —
PPM012467 PGS002202
(portability-ldpred2_log_water_mass)
PSS008352|
South Asian Ancestry|
6,185 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.3789 [0.3573, 0.4001] sex, age, birth date, deprivation index, 16 PCs —
PPM012468 PGS002202
(portability-ldpred2_log_water_mass)
PSS008129|
East Asian Ancestry|
1,782 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.3154 [0.2727, 0.3569] sex, age, birth date, deprivation index, 16 PCs —
PPM012469 PGS002202
(portability-ldpred2_log_water_mass)
PSS007916|
African Ancestry|
2,420 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.2493 [0.2114, 0.2865] sex, age, birth date, deprivation index, 16 PCs —
PPM012470 PGS002202
(portability-ldpred2_log_water_mass)
PSS009020|
African Ancestry|
3,801 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass — — Partial Correlation (partial-r): 0.1924 [0.1615, 0.2229] sex, age, birth date, deprivation index, 16 PCs —
PPM017552 PGS003540
(cont-decay-log_impedance)
PSS010821|
European Ancestry|
4,059 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Impedance of whole body — — partial-R2: 0.16 sex, age, deprivation index, PC1-16 —
PPM017468 PGS003540
(cont-decay-log_impedance)
PSS010905|
European Ancestry|
19,653 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Impedance of whole body — — partial-R2: 0.16 sex, age, deprivation index, PC1-16 —
PPM017636 PGS003540
(cont-decay-log_impedance)
PSS010653|
European Ancestry|
6,373 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Impedance of whole body — — partial-R2: 0.15 sex, age, deprivation index, PC1-16 —
PPM017720 PGS003540
(cont-decay-log_impedance)
PSS010569|
Greater Middle Eastern Ancestry|
1,123 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Impedance of whole body — — partial-R2: 0.16 sex, age, deprivation index, PC1-16 —
PPM017804 PGS003540
(cont-decay-log_impedance)
PSS010233|
European Ancestry|
2,316 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Impedance of whole body — — partial-R2: 0.16 sex, age, deprivation index, PC1-16 —
PPM017888 PGS003540
(cont-decay-log_impedance)
PSS010485|
South Asian Ancestry|
6,127 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Impedance of whole body — — partial-R2: 0.13 sex, age, deprivation index, PC1-16 —
PPM017972 PGS003540
(cont-decay-log_impedance)
PSS010401|
East Asian Ancestry|
1,770 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Impedance of whole body — — partial-R2: 0.08 sex, age, deprivation index, PC1-16 —
PPM018056 PGS003540
(cont-decay-log_impedance)
PSS010317|
African Ancestry|
2,405 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Impedance of whole body — — partial-R2: 0.06 sex, age, deprivation index, PC1-16 —
PPM018140 PGS003540
(cont-decay-log_impedance)
PSS010737|
African Ancestry|
3,770 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Impedance of whole body — — partial-R2: 0.03 sex, age, deprivation index, PC1-16 —
PPM017484 PGS003556
(cont-decay-log_water_mass)
PSS010922|
European Ancestry|
19,662 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Whole body water mass — — partial-R2: 0.2 sex, age, deprivation index, PC1-16 —
PPM017568 PGS003556
(cont-decay-log_water_mass)
PSS010838|
European Ancestry|
4,063 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Whole body water mass — — partial-R2: 0.2 sex, age, deprivation index, PC1-16 —
PPM017652 PGS003556
(cont-decay-log_water_mass)
PSS010670|
European Ancestry|
6,377 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Whole body water mass — — partial-R2: 0.18 sex, age, deprivation index, PC1-16 —
PPM017736 PGS003556
(cont-decay-log_water_mass)
PSS010586|
Greater Middle Eastern Ancestry|
1,124 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Whole body water mass — — partial-R2: 0.15 sex, age, deprivation index, PC1-16 —
PPM017820 PGS003556
(cont-decay-log_water_mass)
PSS010250|
European Ancestry|
2,318 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Whole body water mass — — partial-R2: 0.19 sex, age, deprivation index, PC1-16 —
PPM018072 PGS003556
(cont-decay-log_water_mass)
PSS010334|
African Ancestry|
2,408 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Whole body water mass — — partial-R2: 0.07 sex, age, deprivation index, PC1-16 —
PPM018156 PGS003556
(cont-decay-log_water_mass)
PSS010754|
African Ancestry|
3,773 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Whole body water mass — — partial-R2: 0.03 sex, age, deprivation index, PC1-16 —
PPM017904 PGS003556
(cont-decay-log_water_mass)
PSS010502|
South Asian Ancestry|
6,134 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Whole body water mass — — partial-R2: 0.15 sex, age, deprivation index, PC1-16 —
PPM017988 PGS003556
(cont-decay-log_water_mass)
PSS010418|
East Asian Ancestry|
1,770 individuals
PGP000457 |
Ding Y et al. Nature (2023)
Reported Trait: Whole body water mass — — partial-R2: 0.09 sex, age, deprivation index, PC1-16 —
PPM018829 PGS003902
(INI23102)
PSS011120|
European Ancestry|
66,617 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Whole body water mass — — R²: 0.76001 [0.75686, 0.76316]
PGS R2 (no covariates): 0.0537 [0.0504, 0.057]
Incremental R2 (full-covars): 0.0541
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) —
PPM018830 PGS003902
(INI23102)
PSS011105|
European Ancestry|
2,837 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Whole body water mass — — R²: 0.75815 [0.74282, 0.77347]
PGS R2 (no covariates): 0.0659 [0.04845, 0.08335]
Incremental R2 (full-covars): 0.05792
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) —
PPM018831 PGS003902
(INI23102)
PSS011118|
South Asian Ancestry|
1,457 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Whole body water mass — — R²: 0.69263 [0.66668, 0.71857]
PGS R2 (no covariates): 0.02973 [0.01276, 0.04669]
Incremental R2 (full-covars): 0.04434
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) —
PPM018832 PGS003902
(INI23102)
PSS011158|
African Ancestry|
1,169 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Whole body water mass — — R²: 0.58375 [0.54806, 0.61944]
PGS R2 (no covariates): 0.00794 [-0.00198, 0.01785]
Incremental R2 (full-covars): 0.00256
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) —
PPM018833 PGS003902
(INI23102)
PSS011176|
Multi-ancestry (excluding European)|
7,842 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Whole body water mass — — R²: 0.74875 [0.73923, 0.75827]
PGS R2 (no covariates): 0.03942 [0.03107, 0.04777]
Incremental R2 (full-covars): 0.0395
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) —
PPM020492 PGS004377
(X23102.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: Whole body water mass — — PGS R2 (no covariates): 0.21586 — —

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS005052 — — 1,680 individuals — East Asian — UKB —
PSS005053 — — 24,466 individuals — European non-white British ancestry UKB —
PSS005054 — — 7,649 individuals — South Asian — UKB —
PSS005055 — — 66,264 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS010401 — — 1,770 individuals,
34.0 % Male samples
Mean = 52.4 years
Sd = 7.7 years
East Asian Chinese UKB —
PSS010922 — — 19,662 individuals,
46.0 % Male samples
Mean = 56.9 years
Sd = 7.9 years
European white British UKB —
PSS010670 — — 6,377 individuals,
45.0 % Male samples
Mean = 54.5 years
Sd = 8.4 years
European Italian UKB —
PSS011158 — — 1,169 individuals — African unspecified — UKB —
PSS010418 — — 1,770 individuals,
34.0 % Male samples
Mean = 52.4 years
Sd = 7.7 years
East Asian Chinese UKB —
PSS008800 — — 6,539 individuals — European Italy (South Europe) UKB —
PSS011176 — — 7,842 individuals — East Asian, Other admixed ancestry East Asian, Other admixed ancestry UKB —
PSS010821 — — 4,059 individuals,
38.0 % Male samples
Mean = 54.3 years
Sd = 7.5 years
European Polish UKB —
PSS007916 — — 2,420 individuals — African American or Afro-Caribbean Carribean UKB —
PSS010569 — — 1,123 individuals,
60.0 % Male samples
Mean = 52.0 years
Sd = 7.9 years
Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB —
PSS010317 — — 2,405 individuals,
36.0 % Male samples
Mean = 52.4 years
Sd = 8.1 years
African American or Afro-Caribbean Caribbean UKB —
PSS005051 — — 6,305 individuals — African unspecified — UKB —
PSS010838 — — 4,063 individuals,
38.0 % Male samples
Mean = 54.3 years
Sd = 7.5 years
European Polish UKB —
PSS008574 — — 1,152 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009472 — — 19,641 individuals — European UK (+ Ireland) UKB —
PSS010586 — — 1,124 individuals,
60.0 % Male samples
Mean = 52.0 years
Sd = 7.9 years
Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB —
PSS010334 — — 2,408 individuals,
36.0 % Male samples
Mean = 52.5 years
Sd = 8.1 years
African American or Afro-Caribbean Caribbean UKB —
PSS010737 — — 3,770 individuals,
46.0 % Male samples
Mean = 51.9 years
Sd = 8.1 years
African unspecified Nigerian UKB —
PSS010485 — — 6,127 individuals,
54.0 % Male samples
Mean = 53.3 years
Sd = 8.4 years
South Asian Indian UKB —
PSS009246 — — 4,073 individuals — European Poland (NE Europe) UKB —
PSS010233 — — 2,316 individuals,
45.0 % Male samples
Mean = 58.1 years
Sd = 7.1 years
European Ashkenazi UKB —
PSS008352 — — 6,185 individuals — South Asian India (South Asia) UKB —
PSS011105 — — 2,837 individuals — European
(non-white British ancestry)
— UKB —
PSS011364 — — 56,192 individuals — European — UKB —
PSS010754 — — 3,773 individuals,
46.0 % Male samples
Mean = 51.9 years
Sd = 8.1 years
African unspecified Nigerian UKB —
PSS010502 — — 6,134 individuals,
54.0 % Male samples
Mean = 53.3 years
Sd = 8.4 years
South Asian Indian UKB —
PSS011118 — — 1,457 individuals — South Asian — UKB —
PSS010250 — — 2,318 individuals,
45.0 % Male samples
Mean = 58.0 years
Sd = 7.1 years
European Ashkenazi UKB —
PSS011120 — — 66,617 individuals — European
(white British ancestry)
— UKB —
PSS009020 — — 3,801 individuals — African unspecified Nigeria (West Africa) UKB —
PSS010905 — — 19,653 individuals,
46.0 % Male samples
Mean = 56.9 years
Sd = 7.9 years
European white British UKB —
PSS008129 — — 1,782 individuals — East Asian China (East Asia) UKB —
PSS010653 — — 6,373 individuals,
45.0 % Male samples
Mean = 54.5 years
Sd = 8.4 years
European Italian UKB —