Polygenic Score (PGS) ID: PGS001993

Predicted Trait
Reported Trait Use of sun/uv protection
Mapped Trait(s) sun exposure measurement (EFO_0010729)
Additional Trait Information lifestyle and environment
Released in PGS Catalog: Jan. 10, 2022
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Score Details

Score Construction
PGS Name portability-PLR_more_sunscreen
Development Method
Name Penalized regression (bigstatsr)
Parameters HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 17,282
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 37.5%
African: 25%
East Asian: 12.5%
Greater Middle Eastern: 12.5%
South Asian: 12.5%
8 Sample Sets

Development Samples

Score Development/Training
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
391,124 individuals European UK (+ Ireland) UKB

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010819 PSS009476|
European Ancestry|
19,837 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Use of sun/uv protection Partial Correlation (partial-r): 0.1345 [0.1208, 0.1482] sex, age, birth date, deprivation index, 16 PCs
PPM010820 PSS009250|
European Ancestry|
4,075 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Use of sun/uv protection Partial Correlation (partial-r): 0.0842 [0.0536, 0.1147] sex, age, birth date, deprivation index, 16 PCs
PPM010822 PSS008578|
Greater Middle Eastern Ancestry|
1,095 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Use of sun/uv protection Partial Correlation (partial-r): 0.0891 [0.0295, 0.1481] sex, age, birth date, deprivation index, 16 PCs
PPM010823 PSS008356|
South Asian Ancestry|
5,836 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Use of sun/uv protection Partial Correlation (partial-r): 0.0425 [0.0168, 0.0681] sex, age, birth date, deprivation index, 16 PCs
PPM010824 PSS008133|
East Asian Ancestry|
1,733 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Use of sun/uv protection Partial Correlation (partial-r): 0.049 [0.0016, 0.0961] sex, age, birth date, deprivation index, 16 PCs
PPM010825 PSS007920|
African Ancestry|
2,375 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Use of sun/uv protection Partial Correlation (partial-r): 0.0296 [-0.0108, 0.0699] sex, age, birth date, deprivation index, 16 PCs
PPM010826 PSS009024|
African Ancestry|
3,660 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Use of sun/uv protection Partial Correlation (partial-r): 0.0233 [-0.0092, 0.0558] sex, age, birth date, deprivation index, 16 PCs
PPM010821 PSS008804|
European Ancestry|
6,569 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Use of sun/uv protection Partial Correlation (partial-r): 0.0951 [0.0711, 0.1191] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009476 19,837 individuals European UK (+ Ireland) UKB
PSS008133 1,733 individuals East Asian China (East Asia) UKB
PSS008356 5,836 individuals South Asian India (South Asia) UKB
PSS008804 6,569 individuals European Italy (South Europe) UKB
PSS007920 2,375 individuals African American or Afro-Caribbean Carribean UKB
PSS009250 4,075 individuals European Poland (NE Europe) UKB
PSS009024 3,660 individuals African unspecified Nigeria (West Africa) UKB
PSS008578 1,095 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB