Polygenic Score (PGS) ID: PGS005393

Predicted Trait
Reported Trait Post-traumatic stress disorder
Mapped Trait(s) post-traumatic stress disorder (EFO_0001358)
Released in PGS Catalog: Jan. 19, 2026
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Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name PGS_SEXUAL_ASSAULT_PTSD
Development Method
Name PRSice 2.0
Parameters PRS were adjusted for the first 10 genetic PCs to minimize the influence of potential confounding factors related to population stratification. In addition, the PRS was calculated at multiple p-value thresholds: 0.0001, 0.01, 0.05, 0.1, 0.5, and 1. The raw scores from the best p-threshold were transformed into z scores using PRSice 2.0.
Variants
Original Genome Build GRCh37
Number of Variants 53,705
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000778
Citation (link to publication) Bugiga AVG et al. Braz J Psychiatry (2024)
Ancestry Distribution
Source of Variant
Associations (GWAS)
European: 89.2%
African: 10.8%
195,701 individuals (100%)
PGS Evaluation
Hispanic or Latin American: 100%
1 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
Study Identifiers Sample Numbers Sample Ancestry Cohort(s)
GWAS Catalog: GCST009315
Europe PMC: 31594949
 15,339 individuals African American or Afro-Caribbean, African unspecified NR
GWAS Catalog: GCST009315
Europe PMC: 31594949
 174,659 individuals European NR
GWAS Catalog: GCST009315
Europe PMC: 31594949
 5,703 individuals Native American, Hispanic or Latin American NR

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM023435 PSS012181|
Hispanic or Latin American Ancestry|
117 individuals
 PGP000778 |
Bugiga AVG et al. Braz J Psychiatry (2024)
 Reported Trait: PTSD diagnosis — — R²: 0.087 PC1-PC10 best p-value threshold of 0.333
PPM023436 PSS012181|
Hispanic or Latin American Ancestry|
117 individuals
 PGP000778 |
Bugiga AVG et al. Braz J Psychiatry (2024)
 Reported Trait: PTSD diagnosis OR: 0.035 — — Trauma history, genetic ancestry (10 PCs), age, education, income. best p-value threshold of 0.333

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS012181 — —
[
  • 57 cases
  • , 60 controls
]
 — Hispanic or Latin American
(Brazilian)		 — NR —