PGS Publication: PGP000778

Publication Information (EuropePMC)
Title The interaction between polygenic risk score and trauma affects the likelihood of post-traumatic stress disorder in female victims of sexual assault.
PubMed ID 38467473(Europe PMC)
doi 10.47626/1516-4446-2023-3335
Publication Date March 11, 2024
Journal Braz J Psychiatry
Author(s) Bugiga AVG, Carvalho CM, Oliveira AM, Coimbra BM, Chehimi SN, Zanardo EA, Kulikowski LD, Mello AF, Ota VK, Mello MF, Belangero SI.
Released in PGS Catalog: Jan. 19, 2026

Associated Polygenic Score(s)

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Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
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Not Reported

PGS Developed By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS005393
(PGS_SEXUAL_ASSAULT_PTSD)
 PGP000778 |
Bugiga AVG et al. Braz J Psychiatry (2024)
 Post-traumatic stress disorder post-traumatic stress disorder 53,705
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005393/ScoringFiles/PGS005393.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM023435 PGS005393
(PGS_SEXUAL_ASSAULT_PTSD)
 PSS012181|
Hispanic or Latin American Ancestry|
117 individuals
 PGP000778 |
Bugiga AVG et al. Braz J Psychiatry (2024)
 Reported Trait: PTSD diagnosis — — R²: 0.087 PC1-PC10 best p-value threshold of 0.333
PPM023436 PGS005393
(PGS_SEXUAL_ASSAULT_PTSD)
 PSS012181|
Hispanic or Latin American Ancestry|
117 individuals
 PGP000778 |
Bugiga AVG et al. Braz J Psychiatry (2024)
 Reported Trait: PTSD diagnosis OR: 0.035 — — Trauma history, genetic ancestry (10 PCs), age, education, income. best p-value threshold of 0.333

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS012181 — —
[
  • 57 cases
  • , 60 controls
]
 — Hispanic or Latin American
(Brazilian)		 — NR —