Trait: peripheral vascular disease

Experimental Factor Ontology (EFO) Information
Identifier EFO_0003875
Description Any disorder affecting blood flow through the veins or arteries outside of the heart. [NCIT: C35136]
Trait category
Cardiovascular disease
Synonyms 17 synonyms
  • Angiopathies, Peripheral
  • Angiopathy, Peripheral
  • DIS PERIPHERAL VASCULAR
  • Disease, Peripheral Vascular
  • Diseases, Peripheral Vascular
  • PERIPHERAL VASCULAR DIS
  • Peripheral Angiopathies
  • Peripheral Angiopathy
  • Peripheral Vascular Diseases
  • VASCULAR DIS PERIPHERAL
  • Vascular Disease, Peripheral
  • Vascular Diseases, Peripheral
  • arterial occlusive disease
  • disease, peripheral vascular
  • peripheral vascular disease
  • peripheral vascular disorder
  • vascular disease, peripheral
Mapped terms 12 mapped terms
  • DOID:341
  • ICD10:I73
  • ICD9:443.81
  • MEDGEN:38790
  • MESH:D016481
  • MESH:D016491
  • MONDO:0005294
  • MedDRA:10034633
  • MedDRA:10034635
  • NCIT:C35136
  • SNOMEDCT:400047006
  • UMLS:C0085096
Child trait(s) peripheral arterial disease

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "peripheral vascular disease" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001843
(portability-PLR_443.9)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Peripheral vascular disease, unspecified peripheral vascular disease 242
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001843/ScoringFiles/PGS001843.txt.gz
PGS002055
(portability-ldpred2_443.9)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Peripheral vascular disease, unspecified peripheral vascular disease 599,514
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002055/ScoringFiles/PGS002055.txt.gz
PGS005158
(PRS19_PAD)
 PGP000705 |
Zhu K et al. Diabetes Care (2024)
 Peripheral artery disease peripheral arterial disease 19
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005158/ScoringFiles/PGS005158.txt.gz
PGS005217
(PRS_PAD)
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Peripheral artery disease peripheral arterial disease 1,296,292
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005217/ScoringFiles/PGS005217.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM009634 PGS001843
(portability-PLR_443.9)
 PSS009318|
European Ancestry|
19,668 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): 0.0151 [0.0011, 0.029] sex, age, birth date, deprivation index, 16 PCs —
PPM009636 PGS001843
(portability-PLR_443.9)
 PSS008646|
European Ancestry|
6,566 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): 0.0229 [-0.0013, 0.0471] sex, age, birth date, deprivation index, 16 PCs —
PPM009637 PGS001843
(portability-PLR_443.9)
 PSS008420|
Greater Middle Eastern Ancestry|
1,189 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): -0.0194 [-0.0766, 0.038] sex, age, birth date, deprivation index, 16 PCs —
PPM009638 PGS001843
(portability-PLR_443.9)
 PSS008200|
South Asian Ancestry|
6,258 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): 0.0011 [-0.0237, 0.0259] sex, age, birth date, deprivation index, 16 PCs —
PPM009640 PGS001843
(portability-PLR_443.9)
 PSS007765|
African Ancestry|
2,444 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): -0.0417 [-0.0814, -0.0019] sex, age, birth date, deprivation index, 16 PCs —
PPM009641 PGS001843
(portability-PLR_443.9)
 PSS008869|
African Ancestry|
3,878 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): 0.0129 [-0.0186, 0.0445] sex, age, birth date, deprivation index, 16 PCs —
PPM009635 PGS001843
(portability-PLR_443.9)
 PSS009092|
European Ancestry|
4,063 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): 0.0365 [0.0057, 0.0672] sex, age, birth date, deprivation index, 16 PCs —
PPM009639 PGS001843
(portability-PLR_443.9)
 PSS007982|
East Asian Ancestry|
1,794 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): -0.0031 [-0.0496, 0.0434] sex, age, birth date, deprivation index, 16 PCs —
PPM011302 PGS002055
(portability-ldpred2_443.9)
 PSS009318|
European Ancestry|
19,668 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): 0.0175 [0.0035, 0.0315] sex, age, birth date, deprivation index, 16 PCs —
PPM011304 PGS002055
(portability-ldpred2_443.9)
 PSS008646|
European Ancestry|
6,566 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): 0.0261 [0.0018, 0.0503] sex, age, birth date, deprivation index, 16 PCs —
PPM011305 PGS002055
(portability-ldpred2_443.9)
 PSS008420|
Greater Middle Eastern Ancestry|
1,189 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): -0.0296 [-0.0868, 0.0278] sex, age, birth date, deprivation index, 16 PCs —
PPM011306 PGS002055
(portability-ldpred2_443.9)
 PSS008200|
South Asian Ancestry|
6,258 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): 0.0061 [-0.0187, 0.0309] sex, age, birth date, deprivation index, 16 PCs —
PPM011307 PGS002055
(portability-ldpred2_443.9)
 PSS007982|
East Asian Ancestry|
1,794 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): -0.0276 [-0.074, 0.019] sex, age, birth date, deprivation index, 16 PCs —
PPM011308 PGS002055
(portability-ldpred2_443.9)
 PSS007765|
African Ancestry|
2,444 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): -0.0324 [-0.0721, 0.0074] sex, age, birth date, deprivation index, 16 PCs —
PPM011309 PGS002055
(portability-ldpred2_443.9)
 PSS008869|
African Ancestry|
3,878 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): 0.0345 [0.003, 0.066] sex, age, birth date, deprivation index, 16 PCs —
PPM011303 PGS002055
(portability-ldpred2_443.9)
 PSS009092|
European Ancestry|
4,063 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Peripheral vascular disease, unspecified — — Partial Correlation (partial-r): 0.011 [-0.0198, 0.0418] sex, age, birth date, deprivation index, 16 PCs —
PPM022379 PGS005158
(PRS19_PAD)
 PSS011930|
European Ancestry|
10,836 individuals
 PGP000705 |
Zhu K et al. Diabetes Care (2024)
 Reported Trait: Peripheral artery disease in type 2 diabetes x lifestyle interaction — — Hazard ratio (HR, unfavorable lifestyle and high PRS vs. favorable life style and low PRS): 5.03 [2.74, 9.22] age (continuous, years), sex (male, female), education attainment (college or university degree, A/AS levels or equivalent or O levels/ GCSEs or equivalent or other professional qualifications, or none of the above), Townsend Deprivation Index (continuous), family history of CVD (yes, no), prevalence of hypertension (yes, no), use of antihypertensive medication (yes, no), use of lipid-lowing medication (yes, no), aspirin use (yes, no), diabetes duration (continuous, years), HbA1c (continuous, %), use of diabetes medication (none, only oral medication pills, only insulin, or combination of oral medications and insulin), genotype measurement batch, and the first 10 principal components of ancestry fig 1
PPM022378 PGS005158
(PRS19_PAD)
 PSS011930|
European Ancestry|
10,836 individuals
 PGP000705 |
Zhu K et al. Diabetes Care (2024)
 Reported Trait: Peripheral artery disease in type 2 diabetes HR: 1.13 [1.03, 1.23] — — age (continuous, years), sex (male, female), Townsend Deprivation Index (continuous), race/ethnicity (White, others), education attainment (college or university degree, A/AS levels or equivalent or O levels/GCSEs or equivalent or other professional qualifications, or none of the above), family history of CVD (yes, no), prevalence of hypertension (yes, no), use of antihypertensive medication (yes, no), use of lipidlowing medication (yes, no), use of aspirin (yes, no), diabetes duration (continuous, years), HbA1c (continuous, %), use of diabetes medication (none, only oral medication pills, or only insulin or combination of oral medications and insulin), genotype measurement batch, the first 10 principal components of ancestry, weighted healthy lifestyle scores (continuous) ST3
PPM022599 PGS005217
(PRS_PAD)
 PSS012034|
African Ancestry|
6,939 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident and prevelant peripheral artery disease OR: 1.26 [1.01, 1.59] — R²: 0.051 age, sex and the first ten principal components of genetic ancestry —
PPM022600 PGS005217
(PRS_PAD)
 PSS012035|
East Asian Ancestry|
1,761 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident and prevelant peripheral artery disease OR: 1.6 [1.01, 2.53] — R²: 0.11217 age, sex and the first ten principal components of genetic ancestry —
PPM022601 PGS005217
(PRS_PAD)
 PSS012036|
South Asian Ancestry|
7,680 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident and prevelant peripheral artery disease OR: 1.25 [1.07, 1.46] — R²: 0.07629 age, sex and the first ten principal components of genetic ancestry —
PPM022603 PGS005217
(PRS_PAD)
 PSS012038|
African Ancestry|
51,691 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident and prevelant peripheral artery disease OR: 1.11 [1.06, 1.16] — R²: 0.10751 age, sex and the first ten principal components of genetic ancestry —
PPM022604 PGS005217
(PRS_PAD)
 PSS012039|
East Asian Ancestry|
5,268 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident and prevelant peripheral artery disease OR: 0.98 [0.78, 1.22] — R²: 0.16129 age, sex and the first ten principal components of genetic ancestry —
PPM022605 PGS005217
(PRS_PAD)
 PSS012040|
European Ancestry|
119,167 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident and prevelant peripheral artery disease OR: 1.25 [1.22, 1.27] — R²: 0.12104 age, sex and the first ten principal components of genetic ancestry —
PPM022606 PGS005217
(PRS_PAD)
 PSS012041|
Hispanic or Latin American Ancestry|
39,576 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident and prevelant peripheral artery disease OR: 1.19 [1.13, 1.25] — R²: 0.15203 age, sex and the first ten principal components of genetic ancestry —
PPM022607 PGS005217
(PRS_PAD)
 PSS012028|
Greater Middle Eastern Ancestry|
509 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident and prevelant peripheral artery disease OR: 1.04 [0.62, 1.75] — R²: 0.31662 age, sex and the first ten principal components of genetic ancestry —
PPM022608 PGS005217
(PRS_PAD)
 PSS012029|
South Asian Ancestry|
2,289 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident and prevelant peripheral artery disease OR: 1.34 [1.02, 1.74] — R²: 0.29674 age, sex and the first ten principal components of genetic ancestry —
PPM022609 PGS005217
(PRS_PAD)
 PSS012030|
African Ancestry|
1,945 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident and prevelant peripheral artery disease OR: 1.24 [0.94, 1.63] — R²: 0.11198 age, sex and the first ten principal components of genetic ancestry —
PPM022610 PGS005217
(PRS_PAD)
 PSS012031|
European Ancestry|
32,139 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident and prevelant peripheral artery disease OR: 1.26 [1.17, 1.34] — R²: 0.11467 age, sex and the first ten principal components of genetic ancestry —
PPM022611 PGS005217
(PRS_PAD)
 PSS012032|
Hispanic or Latin American Ancestry|
2,933 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident and prevelant peripheral artery disease OR: 1.22 [0.89, 1.67] — R²: 0.19935 age, sex and the first ten principal components of genetic ancestry —
PPM022612 PGS005217
(PRS_PAD)
 PSS012033|
Multi-ancestry (including European)|
304,294 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident peripheral artery disease HR: 1.66 [1.61, 1.71] C-index: 0.731 — age, sex and the first ten principal components of genetic ancestry —
PPM022598 PGS005217
(PRS_PAD)
 PSS012027|
European Ancestry|
286,356 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident and prevelant peripheral artery disease OR: 1.66 [1.62, 1.71] — R²: 0.0888 age, sex and the first ten principal components of genetic ancestry —
PPM022602 PGS005217
(PRS_PAD)
 PSS012037|
Greater Middle Eastern Ancestry|
7,680 individuals
 PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
 Reported Trait: Incident and prevelant peripheral artery disease OR: 1.62 [1.1, 2.44] — R²: 0.0826 age, sex and the first ten principal components of genetic ancestry —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008646 — — 6,566 individuals — European Italy (South Europe) UKB —
PSS007765 — — 2,444 individuals — African American or Afro-Caribbean Carribean UKB —
PSS008420 — — 1,189 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009318 — — 19,668 individuals — European UK (+ Ireland) UKB —
PSS009092 — — 4,063 individuals — European Poland (NE Europe) UKB —
PSS008200 — — 6,258 individuals — South Asian India (South Asia) UKB —
PSS008869 — — 3,878 individuals — African unspecified Nigeria (West Africa) UKB —
PSS007982 — — 1,794 individuals — East Asian China (East Asia) UKB —
PSS012027 ICD10: I70.0, I70.00, I70.01, I70.2, I70.20, I70.21, I70.8, I70.80, I70.81, I70.9, I70.90, I70.91, I73.8, I73.9 ICD9: 4400, 4402, 4408, 4438, 4439, 9976 OPCS4: X09.1, X09.2, X09.3, X09.4, X09.5, X09.8, X09.9, X10.1, X10.8, X10.9, X12.1, X12.3, X12.4, L16.2, L16.3, L21.6, L25.1, L25.2, L26.1, L26.2, L51.1, L51.2, L51.3, L51.4, L51.6, L51.8, L52.1, L52.2, L54.1, L54.4, L54.8, L54.9, L59.1, L59.2, L59.3, L59.4, L59.5, L59.6, L59.7, L59.8, L59.9, L60.1, L60.2, L60.3, L60.4, L60.8, L60.9, L63.1, L63.5, L63.8, L63.9, L66.5, L66.7, L66.8, L66.9, L68.1, L68.2, L71.1, L71.5, L71.7, L71.8, L71.9 OPCS3: 873, 874, 881, 8841 Median = 12.1 years
[
  • 6,205 cases
  • , 280,151 controls
]
 — European — UKB Independent individuals from training sample
PSS012028 ICD-9 Diagnosis: 4400, 44020, 44021, 44022, 44023, 44024, 44029, 44030, 44031, 44032, 4404, 4408, 4439, 4471 ICD-10 Diagnosis: I700, I70201, I70202, I70203, I70209, I70211, I70212, I70213, I70219, I70221, I70222, I70223, I7025, I70229, I70231, I70232, I70233, I70234, I70235, I70238, I70239, I70241, I70242, I70243, I70244, I70245, I70248, I70249, I70261, I70262, I70263, I70269, I70291, I70292, I70293, I70299, I70301, I70302, I70303, I70309, I70311, I70312, I70313, I70319, I70321, I70322, I70323, I70329, I70331, I70332, I70333, I70334, I70335, I70338, I70339, I70341, I70342, I70343, I70344, I70345, I70348, I70349, I70361, I70362, I70363, I70369, I70391, I70392, I70393, I70399, I70401, I70402, I70403, I70409, I70411, I70412, I70413, I70419, I70421, I70422, I70423, I70429, I70431, I70432, I70433, I70434, I70435, I70438, I70439, I70441, I70442, I70443, I70444, I70445, I70448, I70449, I70461, I70462, I70463, I70469, I70491, I70492, I70493, I70499, I70501, I70502, I70503, I70509, I70511, I70512, I70513, I70519, I70521, I70522, I70523, I70529, I70531, I70532, I70533, I70534, I70535, I70538, I70539, I70541, I70542, I70543, I70544, I70545, I70548, I70549, I70561, I70562, I70563, I70569, I70591, I70592, I70593, I70599, I70601, I70602, I70603, I70609, I70611, I70612, I70613, I70619, I70621, I70622, I70623, I70629, I70631, I70632, I70633, I70634, I70635, I70638, I70639, I70641, I70642, I70643, I70644, I70645, I70648, I70649, I70661, I70662, I70663, I70669, I70691, I70692, I70693, I70699, I70701, I70702, I70703, I70709, I70711, I70712, I70713, I70719, I70721, I70722, I70723, I70729, I70731, I70732, I70733, I70734, I70735, I70738, I70739, I70741, I70742, I70743, I70744, I70745, I70748, I70749, I70761, I70762, I70763, I70769, I70791, I70792, I70793, I70799, I7092, I739, I771 CPT: 93668, 27290, 27295, 27590, 27592, 27594, 27596, 27598, 27880, 27881, 27882, 27884, 27886, 27888, 35302, 35303, 35304, 35305, 35306, 35331, 35351, 35355, 35361, 35363, 35371, 35372, 35452, 35454, 35456, 35459, 35470, 35472, 35473, 35474, 35481, 35482, 35483, 35485, 35491, 35492, 35493, 35495, 35521, 35533, 35537, 35538, 35539, 35540, 35548, 35549, 35551, 35556, 35558, 35563, 35565, 35566, 35571, 35583, 35585, 35587, 35621, 35623, 35637, 35638, 35646, 35647, 35654, 35656, 35661, 35663, 35665, 35666, 35671, 35876, 35879, 35881, 35883, 35884, 37220, 37221, 37222, 37223, 37224, 37225, 37226, 37227, 37228, 37229, 37230, 37231, 37232, 37233, 37234, 37235, 35381, 35541, 35546, 35582, 35651, 35641 ICD-9 Procedure: 38.18, 39.25, 39.29, 39.5, 39.9, 84.1, 84.12, 84.13, 84.14, 84.15, 84.16, 84.17, 84.18, 84.19, 84.3 ICD-10 Procedure: 041C***, 041D***, 041F***, 041H***, 041J***, 041K***, 041L***, 041M***, 041N***, 041U***, 0470***, 047C***, 047D***, 047E***, 047F***, 047H***, 047J***, 047K***, 047L***, 047M***, 047N***, 047P***, 047Q***, 047R***, 047S***, 047T***, 047U***, 047V***, 047W***, 047Y***, 04C0***, 04CC***, 04CD***, 04CE***, 04CF***, 04CH***, 04CJ***, 04CK***, 04CL***, 04CM***, 04CN***, 04CP***, 04CQ***, 04CR***, 04CS***, 04CT***, 04CU***, 04CV***, 04CW***, 04CY***, 0Y62***, 0Y63***, 0Y68***, 0Y6C***, 0Y6D***, 0Y6F***, 0Y6G***, 0Y6H***, 0Y6J***, 0Y6M***, 0Y6N*** Median = 2.32 years
[
  • 20 cases
  • , 489 controls
]
 — Greater Middle Eastern (Middle Eastern, North African or Persian) — AllofUs —
PSS012029 ICD-9 Diagnosis: 4400, 44020, 44021, 44022, 44023, 44024, 44029, 44030, 44031, 44032, 4404, 4408, 4439, 4471 ICD-10 Diagnosis: I700, I70201, I70202, I70203, I70209, I70211, I70212, I70213, I70219, I70221, I70222, I70223, I7025, I70229, I70231, I70232, I70233, I70234, I70235, I70238, I70239, I70241, I70242, I70243, I70244, I70245, I70248, I70249, I70261, I70262, I70263, I70269, I70291, I70292, I70293, I70299, I70301, I70302, I70303, I70309, I70311, I70312, I70313, I70319, I70321, I70322, I70323, I70329, I70331, I70332, I70333, I70334, I70335, I70338, I70339, I70341, I70342, I70343, I70344, I70345, I70348, I70349, I70361, I70362, I70363, I70369, I70391, I70392, I70393, I70399, I70401, I70402, I70403, I70409, I70411, I70412, I70413, I70419, I70421, I70422, I70423, I70429, I70431, I70432, I70433, I70434, I70435, I70438, I70439, I70441, I70442, I70443, I70444, I70445, I70448, I70449, I70461, I70462, I70463, I70469, I70491, I70492, I70493, I70499, I70501, I70502, I70503, I70509, I70511, I70512, I70513, I70519, I70521, I70522, I70523, I70529, I70531, I70532, I70533, I70534, I70535, I70538, I70539, I70541, I70542, I70543, I70544, I70545, I70548, I70549, I70561, I70562, I70563, I70569, I70591, I70592, I70593, I70599, I70601, I70602, I70603, I70609, I70611, I70612, I70613, I70619, I70621, I70622, I70623, I70629, I70631, I70632, I70633, I70634, I70635, I70638, I70639, I70641, I70642, I70643, I70644, I70645, I70648, I70649, I70661, I70662, I70663, I70669, I70691, I70692, I70693, I70699, I70701, I70702, I70703, I70709, I70711, I70712, I70713, I70719, I70721, I70722, I70723, I70729, I70731, I70732, I70733, I70734, I70735, I70738, I70739, I70741, I70742, I70743, I70744, I70745, I70748, I70749, I70761, I70762, I70763, I70769, I70791, I70792, I70793, I70799, I7092, I739, I771 CPT: 93668, 27290, 27295, 27590, 27592, 27594, 27596, 27598, 27880, 27881, 27882, 27884, 27886, 27888, 35302, 35303, 35304, 35305, 35306, 35331, 35351, 35355, 35361, 35363, 35371, 35372, 35452, 35454, 35456, 35459, 35470, 35472, 35473, 35474, 35481, 35482, 35483, 35485, 35491, 35492, 35493, 35495, 35521, 35533, 35537, 35538, 35539, 35540, 35548, 35549, 35551, 35556, 35558, 35563, 35565, 35566, 35571, 35583, 35585, 35587, 35621, 35623, 35637, 35638, 35646, 35647, 35654, 35656, 35661, 35663, 35665, 35666, 35671, 35876, 35879, 35881, 35883, 35884, 37220, 37221, 37222, 37223, 37224, 37225, 37226, 37227, 37228, 37229, 37230, 37231, 37232, 37233, 37234, 37235, 35381, 35541, 35546, 35582, 35651, 35641 ICD-9 Procedure: 38.18, 39.25, 39.29, 39.5, 39.9, 84.1, 84.12, 84.13, 84.14, 84.15, 84.16, 84.17, 84.18, 84.19, 84.3 ICD-10 Procedure: 041C***, 041D***, 041F***, 041H***, 041J***, 041K***, 041L***, 041M***, 041N***, 041U***, 0470***, 047C***, 047D***, 047E***, 047F***, 047H***, 047J***, 047K***, 047L***, 047M***, 047N***, 047P***, 047Q***, 047R***, 047S***, 047T***, 047U***, 047V***, 047W***, 047Y***, 04C0***, 04CC***, 04CD***, 04CE***, 04CF***, 04CH***, 04CJ***, 04CK***, 04CL***, 04CM***, 04CN***, 04CP***, 04CQ***, 04CR***, 04CS***, 04CT***, 04CU***, 04CV***, 04CW***, 04CY***, 0Y62***, 0Y63***, 0Y68***, 0Y6C***, 0Y6D***, 0Y6F***, 0Y6G***, 0Y6H***, 0Y6J***, 0Y6M***, 0Y6N*** Median = 2.32 years
[
  • 66 cases
  • , 2,223 controls
]
 — South Asian — AllofUs —
PSS012030 Phenotype constructed using NLP applied to unstructured EHR text and ICD10 codes: Median = 5.19 years
[
  • 58 cases
  • , 1,887 controls
]
 — African American or Afro-Caribbean — MGBB —
PSS012031 Phenotype constructed using NLP applied to unstructured EHR text and ICD10 codes: Median = 5.19 years
[
  • 924 cases
  • , 31,215 controls
]
 — European — MGBB —
PSS012032 Phenotype constructed using NLP applied to unstructured EHR text and ICD10 codes: Median = 5.19 years
[
  • 46 cases
  • , 2,887 controls
]
 — Hispanic or Latin American — MGBB —
PSS012033 ICD10: I70.0, I70.00, I70.01, I70.2, I70.20, I70.21, I70.8, I70.80, I70.81, I70.9, I70.90, I70.91, I73.8, I73.9 ICD9: 4400, 4402, 4408, 4438, 4439, 9976 OPCS4: X09.1, X09.2, X09.3, X09.4, X09.5, X09.8, X09.9, X10.1, X10.8, X10.9, X12.1, X12.3, X12.4, L16.2, L16.3, L21.6, L25.1, L25.2, L26.1, L26.2, L51.1, L51.2, L51.3, L51.4, L51.6, L51.8, L52.1, L52.2, L54.1, L54.4, L54.8, L54.9, L59.1, L59.2, L59.3, L59.4, L59.5, L59.6, L59.7, L59.8, L59.9, L60.1, L60.2, L60.3, L60.4, L60.8, L60.9, L63.1, L63.5, L63.8, L63.9, L66.5, L66.7, L66.8, L66.9, L68.1, L68.2, L71.1, L71.5, L71.7, L71.8, L71.9 OPCS3: 873, 874, 881, 8841 Median = 12.1 years
[
  • 6,564 cases
  • , 297,730 controls
]
 — African American or Afro-Caribbean, East Asian, European, Greater Middle Eastern (Middle Eastern, North African or Persian), South Asian — UKB —
PSS012034 ICD10: I70.0, I70.00, I70.01, I70.2, I70.20, I70.21, I70.8, I70.80, I70.81, I70.9, I70.90, I70.91, I73.8, I73.9 ICD9: 4400, 4402, 4408, 4438, 4439, 9976 OPCS4: X09.1, X09.2, X09.3, X09.4, X09.5, X09.8, X09.9, X10.1, X10.8, X10.9, X12.1, X12.3, X12.4, L16.2, L16.3, L21.6, L25.1, L25.2, L26.1, L26.2, L51.1, L51.2, L51.3, L51.4, L51.6, L51.8, L52.1, L52.2, L54.1, L54.4, L54.8, L54.9, L59.1, L59.2, L59.3, L59.4, L59.5, L59.6, L59.7, L59.8, L59.9, L60.1, L60.2, L60.3, L60.4, L60.8, L60.9, L63.1, L63.5, L63.8, L63.9, L66.5, L66.7, L66.8, L66.9, L68.1, L68.2, L71.1, L71.5, L71.7, L71.8, L71.9 OPCS3: 873, 874, 881, 8841 Median = 12.1 years
[
  • 126 cases
  • , 6,813 controls
]
 — African unspecified — UKB —
PSS012035 ICD10: I70.0, I70.00, I70.01, I70.2, I70.20, I70.21, I70.8, I70.80, I70.81, I70.9, I70.90, I70.91, I73.8, I73.9 ICD9: 4400, 4402, 4408, 4438, 4439, 9976 OPCS4: X09.1, X09.2, X09.3, X09.4, X09.5, X09.8, X09.9, X10.1, X10.8, X10.9, X12.1, X12.3, X12.4, L16.2, L16.3, L21.6, L25.1, L25.2, L26.1, L26.2, L51.1, L51.2, L51.3, L51.4, L51.6, L51.8, L52.1, L52.2, L54.1, L54.4, L54.8, L54.9, L59.1, L59.2, L59.3, L59.4, L59.5, L59.6, L59.7, L59.8, L59.9, L60.1, L60.2, L60.3, L60.4, L60.8, L60.9, L63.1, L63.5, L63.8, L63.9, L66.5, L66.7, L66.8, L66.9, L68.1, L68.2, L71.1, L71.5, L71.7, L71.8, L71.9 OPCS3: 873, 874, 881, 8841 Median = 12.1 years
[
  • 20 cases
  • , 1,741 controls
]
 — East Asian — UKB —
PSS012036 ICD10: I70.0, I70.00, I70.01, I70.2, I70.20, I70.21, I70.8, I70.80, I70.81, I70.9, I70.90, I70.91, I73.8, I73.9 ICD9: 4400, 4402, 4408, 4438, 4439, 9976 OPCS4: X09.1, X09.2, X09.3, X09.4, X09.5, X09.8, X09.9, X10.1, X10.8, X10.9, X12.1, X12.3, X12.4, L16.2, L16.3, L21.6, L25.1, L25.2, L26.1, L26.2, L51.1, L51.2, L51.3, L51.4, L51.6, L51.8, L52.1, L52.2, L54.1, L54.4, L54.8, L54.9, L59.1, L59.2, L59.3, L59.4, L59.5, L59.6, L59.7, L59.8, L59.9, L60.1, L60.2, L60.3, L60.4, L60.8, L60.9, L63.1, L63.5, L63.8, L63.9, L66.5, L66.7, L66.8, L66.9, L68.1, L68.2, L71.1, L71.5, L71.7, L71.8, L71.9 OPCS3: 873, 874, 881, 8841 Median = 12.1 years
[
  • 183 cases
  • , 7,497 controls
]
 — South Asian — UKB —
PSS012037 ICD10: I70.0, I70.00, I70.01, I70.2, I70.20, I70.21, I70.8, I70.80, I70.81, I70.9, I70.90, I70.91, I73.8, I73.9 ICD9: 4400, 4402, 4408, 4438, 4439, 9976 OPCS4: X09.1, X09.2, X09.3, X09.4, X09.5, X09.8, X09.9, X10.1, X10.8, X10.9, X12.1, X12.3, X12.4, L16.2, L16.3, L21.6, L25.1, L25.2, L26.1, L26.2, L51.1, L51.2, L51.3, L51.4, L51.6, L51.8, L52.1, L52.2, L54.1, L54.4, L54.8, L54.9, L59.1, L59.2, L59.3, L59.4, L59.5, L59.6, L59.7, L59.8, L59.9, L60.1, L60.2, L60.3, L60.4, L60.8, L60.9, L63.1, L63.5, L63.8, L63.9, L66.5, L66.7, L66.8, L66.9, L68.1, L68.2, L71.1, L71.5, L71.7, L71.8, L71.9 OPCS3: 873, 874, 881, 8841 Median = 12.1 years
[
  • 183 cases
  • , 7,497 controls
]
 — Greater Middle Eastern (Middle Eastern, North African or Persian) — UKB —
PSS012038 ICD-9 Diagnosis: 4400, 44020, 44021, 44022, 44023, 44024, 44029, 44030, 44031, 44032, 4404, 4408, 4439, 4471 ICD-10 Diagnosis: I700, I70201, I70202, I70203, I70209, I70211, I70212, I70213, I70219, I70221, I70222, I70223, I7025, I70229, I70231, I70232, I70233, I70234, I70235, I70238, I70239, I70241, I70242, I70243, I70244, I70245, I70248, I70249, I70261, I70262, I70263, I70269, I70291, I70292, I70293, I70299, I70301, I70302, I70303, I70309, I70311, I70312, I70313, I70319, I70321, I70322, I70323, I70329, I70331, I70332, I70333, I70334, I70335, I70338, I70339, I70341, I70342, I70343, I70344, I70345, I70348, I70349, I70361, I70362, I70363, I70369, I70391, I70392, I70393, I70399, I70401, I70402, I70403, I70409, I70411, I70412, I70413, I70419, I70421, I70422, I70423, I70429, I70431, I70432, I70433, I70434, I70435, I70438, I70439, I70441, I70442, I70443, I70444, I70445, I70448, I70449, I70461, I70462, I70463, I70469, I70491, I70492, I70493, I70499, I70501, I70502, I70503, I70509, I70511, I70512, I70513, I70519, I70521, I70522, I70523, I70529, I70531, I70532, I70533, I70534, I70535, I70538, I70539, I70541, I70542, I70543, I70544, I70545, I70548, I70549, I70561, I70562, I70563, I70569, I70591, I70592, I70593, I70599, I70601, I70602, I70603, I70609, I70611, I70612, I70613, I70619, I70621, I70622, I70623, I70629, I70631, I70632, I70633, I70634, I70635, I70638, I70639, I70641, I70642, I70643, I70644, I70645, I70648, I70649, I70661, I70662, I70663, I70669, I70691, I70692, I70693, I70699, I70701, I70702, I70703, I70709, I70711, I70712, I70713, I70719, I70721, I70722, I70723, I70729, I70731, I70732, I70733, I70734, I70735, I70738, I70739, I70741, I70742, I70743, I70744, I70745, I70748, I70749, I70761, I70762, I70763, I70769, I70791, I70792, I70793, I70799, I7092, I739, I771 CPT: 93668, 27290, 27295, 27590, 27592, 27594, 27596, 27598, 27880, 27881, 27882, 27884, 27886, 27888, 35302, 35303, 35304, 35305, 35306, 35331, 35351, 35355, 35361, 35363, 35371, 35372, 35452, 35454, 35456, 35459, 35470, 35472, 35473, 35474, 35481, 35482, 35483, 35485, 35491, 35492, 35493, 35495, 35521, 35533, 35537, 35538, 35539, 35540, 35548, 35549, 35551, 35556, 35558, 35563, 35565, 35566, 35571, 35583, 35585, 35587, 35621, 35623, 35637, 35638, 35646, 35647, 35654, 35656, 35661, 35663, 35665, 35666, 35671, 35876, 35879, 35881, 35883, 35884, 37220, 37221, 37222, 37223, 37224, 37225, 37226, 37227, 37228, 37229, 37230, 37231, 37232, 37233, 37234, 37235, 35381, 35541, 35546, 35582, 35651, 35641 ICD-9 Procedure: 38.18, 39.25, 39.29, 39.5, 39.9, 84.1, 84.12, 84.13, 84.14, 84.15, 84.16, 84.17, 84.18, 84.19, 84.3 ICD-10 Procedure: 041C***, 041D***, 041F***, 041H***, 041J***, 041K***, 041L***, 041M***, 041N***, 041U***, 0470***, 047C***, 047D***, 047E***, 047F***, 047H***, 047J***, 047K***, 047L***, 047M***, 047N***, 047P***, 047Q***, 047R***, 047S***, 047T***, 047U***, 047V***, 047W***, 047Y***, 04C0***, 04CC***, 04CD***, 04CE***, 04CF***, 04CH***, 04CJ***, 04CK***, 04CL***, 04CM***, 04CN***, 04CP***, 04CQ***, 04CR***, 04CS***, 04CT***, 04CU***, 04CV***, 04CW***, 04CY***, 0Y62***, 0Y63***, 0Y68***, 0Y6C***, 0Y6D***, 0Y6F***, 0Y6G***, 0Y6H***, 0Y6J***, 0Y6M***, 0Y6N*** Median = 2.32 years
[
  • 3,043 cases
  • , 48,648 controls
]
 — African American or Afro-Caribbean — AllofUs —
PSS012039 ICD-9 Diagnosis: 4400, 44020, 44021, 44022, 44023, 44024, 44029, 44030, 44031, 44032, 4404, 4408, 4439, 4471 ICD-10 Diagnosis: I700, I70201, I70202, I70203, I70209, I70211, I70212, I70213, I70219, I70221, I70222, I70223, I7025, I70229, I70231, I70232, I70233, I70234, I70235, I70238, I70239, I70241, I70242, I70243, I70244, I70245, I70248, I70249, I70261, I70262, I70263, I70269, I70291, I70292, I70293, I70299, I70301, I70302, I70303, I70309, I70311, I70312, I70313, I70319, I70321, I70322, I70323, I70329, I70331, I70332, I70333, I70334, I70335, I70338, I70339, I70341, I70342, I70343, I70344, I70345, I70348, I70349, I70361, I70362, I70363, I70369, I70391, I70392, I70393, I70399, I70401, I70402, I70403, I70409, I70411, I70412, I70413, I70419, I70421, I70422, I70423, I70429, I70431, I70432, I70433, I70434, I70435, I70438, I70439, I70441, I70442, I70443, I70444, I70445, I70448, I70449, I70461, I70462, I70463, I70469, I70491, I70492, I70493, I70499, I70501, I70502, I70503, I70509, I70511, I70512, I70513, I70519, I70521, I70522, I70523, I70529, I70531, I70532, I70533, I70534, I70535, I70538, I70539, I70541, I70542, I70543, I70544, I70545, I70548, I70549, I70561, I70562, I70563, I70569, I70591, I70592, I70593, I70599, I70601, I70602, I70603, I70609, I70611, I70612, I70613, I70619, I70621, I70622, I70623, I70629, I70631, I70632, I70633, I70634, I70635, I70638, I70639, I70641, I70642, I70643, I70644, I70645, I70648, I70649, I70661, I70662, I70663, I70669, I70691, I70692, I70693, I70699, I70701, I70702, I70703, I70709, I70711, I70712, I70713, I70719, I70721, I70722, I70723, I70729, I70731, I70732, I70733, I70734, I70735, I70738, I70739, I70741, I70742, I70743, I70744, I70745, I70748, I70749, I70761, I70762, I70763, I70769, I70791, I70792, I70793, I70799, I7092, I739, I771 CPT: 93668, 27290, 27295, 27590, 27592, 27594, 27596, 27598, 27880, 27881, 27882, 27884, 27886, 27888, 35302, 35303, 35304, 35305, 35306, 35331, 35351, 35355, 35361, 35363, 35371, 35372, 35452, 35454, 35456, 35459, 35470, 35472, 35473, 35474, 35481, 35482, 35483, 35485, 35491, 35492, 35493, 35495, 35521, 35533, 35537, 35538, 35539, 35540, 35548, 35549, 35551, 35556, 35558, 35563, 35565, 35566, 35571, 35583, 35585, 35587, 35621, 35623, 35637, 35638, 35646, 35647, 35654, 35656, 35661, 35663, 35665, 35666, 35671, 35876, 35879, 35881, 35883, 35884, 37220, 37221, 37222, 37223, 37224, 37225, 37226, 37227, 37228, 37229, 37230, 37231, 37232, 37233, 37234, 37235, 35381, 35541, 35546, 35582, 35651, 35641 ICD-9 Procedure: 38.18, 39.25, 39.29, 39.5, 39.9, 84.1, 84.12, 84.13, 84.14, 84.15, 84.16, 84.17, 84.18, 84.19, 84.3 ICD-10 Procedure: 041C***, 041D***, 041F***, 041H***, 041J***, 041K***, 041L***, 041M***, 041N***, 041U***, 0470***, 047C***, 047D***, 047E***, 047F***, 047H***, 047J***, 047K***, 047L***, 047M***, 047N***, 047P***, 047Q***, 047R***, 047S***, 047T***, 047U***, 047V***, 047W***, 047Y***, 04C0***, 04CC***, 04CD***, 04CE***, 04CF***, 04CH***, 04CJ***, 04CK***, 04CL***, 04CM***, 04CN***, 04CP***, 04CQ***, 04CR***, 04CS***, 04CT***, 04CU***, 04CV***, 04CW***, 04CY***, 0Y62***, 0Y63***, 0Y68***, 0Y6C***, 0Y6D***, 0Y6F***, 0Y6G***, 0Y6H***, 0Y6J***, 0Y6M***, 0Y6N*** Median = 2.32 years
[
  • 114 cases
  • , 5,154 controls
]
 — East Asian — AllofUs —
PSS012040 ICD-9 Diagnosis: 4400, 44020, 44021, 44022, 44023, 44024, 44029, 44030, 44031, 44032, 4404, 4408, 4439, 4471 ICD-10 Diagnosis: I700, I70201, I70202, I70203, I70209, I70211, I70212, I70213, I70219, I70221, I70222, I70223, I7025, I70229, I70231, I70232, I70233, I70234, I70235, I70238, I70239, I70241, I70242, I70243, I70244, I70245, I70248, I70249, I70261, I70262, I70263, I70269, I70291, I70292, I70293, I70299, I70301, I70302, I70303, I70309, I70311, I70312, I70313, I70319, I70321, I70322, I70323, I70329, I70331, I70332, I70333, I70334, I70335, I70338, I70339, I70341, I70342, I70343, I70344, I70345, I70348, I70349, I70361, I70362, I70363, I70369, I70391, I70392, I70393, I70399, I70401, I70402, I70403, I70409, I70411, I70412, I70413, I70419, I70421, I70422, I70423, I70429, I70431, I70432, I70433, I70434, I70435, I70438, I70439, I70441, I70442, I70443, I70444, I70445, I70448, I70449, I70461, I70462, I70463, I70469, I70491, I70492, I70493, I70499, I70501, I70502, I70503, I70509, I70511, I70512, I70513, I70519, I70521, I70522, I70523, I70529, I70531, I70532, I70533, I70534, I70535, I70538, I70539, I70541, I70542, I70543, I70544, I70545, I70548, I70549, I70561, I70562, I70563, I70569, I70591, I70592, I70593, I70599, I70601, I70602, I70603, I70609, I70611, I70612, I70613, I70619, I70621, I70622, I70623, I70629, I70631, I70632, I70633, I70634, I70635, I70638, I70639, I70641, I70642, I70643, I70644, I70645, I70648, I70649, I70661, I70662, I70663, I70669, I70691, I70692, I70693, I70699, I70701, I70702, I70703, I70709, I70711, I70712, I70713, I70719, I70721, I70722, I70723, I70729, I70731, I70732, I70733, I70734, I70735, I70738, I70739, I70741, I70742, I70743, I70744, I70745, I70748, I70749, I70761, I70762, I70763, I70769, I70791, I70792, I70793, I70799, I7092, I739, I771 CPT: 93668, 27290, 27295, 27590, 27592, 27594, 27596, 27598, 27880, 27881, 27882, 27884, 27886, 27888, 35302, 35303, 35304, 35305, 35306, 35331, 35351, 35355, 35361, 35363, 35371, 35372, 35452, 35454, 35456, 35459, 35470, 35472, 35473, 35474, 35481, 35482, 35483, 35485, 35491, 35492, 35493, 35495, 35521, 35533, 35537, 35538, 35539, 35540, 35548, 35549, 35551, 35556, 35558, 35563, 35565, 35566, 35571, 35583, 35585, 35587, 35621, 35623, 35637, 35638, 35646, 35647, 35654, 35656, 35661, 35663, 35665, 35666, 35671, 35876, 35879, 35881, 35883, 35884, 37220, 37221, 37222, 37223, 37224, 37225, 37226, 37227, 37228, 37229, 37230, 37231, 37232, 37233, 37234, 37235, 35381, 35541, 35546, 35582, 35651, 35641 ICD-9 Procedure: 38.18, 39.25, 39.29, 39.5, 39.9, 84.1, 84.12, 84.13, 84.14, 84.15, 84.16, 84.17, 84.18, 84.19, 84.3 ICD-10 Procedure: 041C***, 041D***, 041F***, 041H***, 041J***, 041K***, 041L***, 041M***, 041N***, 041U***, 0470***, 047C***, 047D***, 047E***, 047F***, 047H***, 047J***, 047K***, 047L***, 047M***, 047N***, 047P***, 047Q***, 047R***, 047S***, 047T***, 047U***, 047V***, 047W***, 047Y***, 04C0***, 04CC***, 04CD***, 04CE***, 04CF***, 04CH***, 04CJ***, 04CK***, 04CL***, 04CM***, 04CN***, 04CP***, 04CQ***, 04CR***, 04CS***, 04CT***, 04CU***, 04CV***, 04CW***, 04CY***, 0Y62***, 0Y63***, 0Y68***, 0Y6C***, 0Y6D***, 0Y6F***, 0Y6G***, 0Y6H***, 0Y6J***, 0Y6M***, 0Y6N*** Median = 2.32 years
[
  • 7,572 cases
  • , 111,595 controls
]
 — European — AllofUs —
PSS012041 ICD-9 Diagnosis: 4400, 44020, 44021, 44022, 44023, 44024, 44029, 44030, 44031, 44032, 4404, 4408, 4439, 4471 ICD-10 Diagnosis: I700, I70201, I70202, I70203, I70209, I70211, I70212, I70213, I70219, I70221, I70222, I70223, I7025, I70229, I70231, I70232, I70233, I70234, I70235, I70238, I70239, I70241, I70242, I70243, I70244, I70245, I70248, I70249, I70261, I70262, I70263, I70269, I70291, I70292, I70293, I70299, I70301, I70302, I70303, I70309, I70311, I70312, I70313, I70319, I70321, I70322, I70323, I70329, I70331, I70332, I70333, I70334, I70335, I70338, I70339, I70341, I70342, I70343, I70344, I70345, I70348, I70349, I70361, I70362, I70363, I70369, I70391, I70392, I70393, I70399, I70401, I70402, I70403, I70409, I70411, I70412, I70413, I70419, I70421, I70422, I70423, I70429, I70431, I70432, I70433, I70434, I70435, I70438, I70439, I70441, I70442, I70443, I70444, I70445, I70448, I70449, I70461, I70462, I70463, I70469, I70491, I70492, I70493, I70499, I70501, I70502, I70503, I70509, I70511, I70512, I70513, I70519, I70521, I70522, I70523, I70529, I70531, I70532, I70533, I70534, I70535, I70538, I70539, I70541, I70542, I70543, I70544, I70545, I70548, I70549, I70561, I70562, I70563, I70569, I70591, I70592, I70593, I70599, I70601, I70602, I70603, I70609, I70611, I70612, I70613, I70619, I70621, I70622, I70623, I70629, I70631, I70632, I70633, I70634, I70635, I70638, I70639, I70641, I70642, I70643, I70644, I70645, I70648, I70649, I70661, I70662, I70663, I70669, I70691, I70692, I70693, I70699, I70701, I70702, I70703, I70709, I70711, I70712, I70713, I70719, I70721, I70722, I70723, I70729, I70731, I70732, I70733, I70734, I70735, I70738, I70739, I70741, I70742, I70743, I70744, I70745, I70748, I70749, I70761, I70762, I70763, I70769, I70791, I70792, I70793, I70799, I7092, I739, I771 CPT: 93668, 27290, 27295, 27590, 27592, 27594, 27596, 27598, 27880, 27881, 27882, 27884, 27886, 27888, 35302, 35303, 35304, 35305, 35306, 35331, 35351, 35355, 35361, 35363, 35371, 35372, 35452, 35454, 35456, 35459, 35470, 35472, 35473, 35474, 35481, 35482, 35483, 35485, 35491, 35492, 35493, 35495, 35521, 35533, 35537, 35538, 35539, 35540, 35548, 35549, 35551, 35556, 35558, 35563, 35565, 35566, 35571, 35583, 35585, 35587, 35621, 35623, 35637, 35638, 35646, 35647, 35654, 35656, 35661, 35663, 35665, 35666, 35671, 35876, 35879, 35881, 35883, 35884, 37220, 37221, 37222, 37223, 37224, 37225, 37226, 37227, 37228, 37229, 37230, 37231, 37232, 37233, 37234, 37235, 35381, 35541, 35546, 35582, 35651, 35641 ICD-9 Procedure: 38.18, 39.25, 39.29, 39.5, 39.9, 84.1, 84.12, 84.13, 84.14, 84.15, 84.16, 84.17, 84.18, 84.19, 84.3 ICD-10 Procedure: 041C***, 041D***, 041F***, 041H***, 041J***, 041K***, 041L***, 041M***, 041N***, 041U***, 0470***, 047C***, 047D***, 047E***, 047F***, 047H***, 047J***, 047K***, 047L***, 047M***, 047N***, 047P***, 047Q***, 047R***, 047S***, 047T***, 047U***, 047V***, 047W***, 047Y***, 04C0***, 04CC***, 04CD***, 04CE***, 04CF***, 04CH***, 04CJ***, 04CK***, 04CL***, 04CM***, 04CN***, 04CP***, 04CQ***, 04CR***, 04CS***, 04CT***, 04CU***, 04CV***, 04CW***, 04CY***, 0Y62***, 0Y63***, 0Y68***, 0Y6C***, 0Y6D***, 0Y6F***, 0Y6G***, 0Y6H***, 0Y6J***, 0Y6M***, 0Y6N*** Median = 2.32 years
[
  • 1,652 cases
  • , 37,924 controls
]
 — Hispanic or Latin American — AllofUs —
PSS011930 — — 10,836 individuals — European
(British)		 — UKB —