Trait: alcohol drinking

Experimental Factor Ontology (EFO) Information
Identifier EFO_0004329
Description Behaviors associated with the ingesting of alcoholic beverages, including social drinking.
Trait category
Biological process
Synonym alcohol consumption
Mapped terms 2 mapped terms
  • MeSH:D000428
  • NCIt:C16273

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS001901
(portability-PLR_drink_alcohol)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Alcohol drinker status alcohol drinking 1,065
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001901/ScoringFiles/PGS001901.txt.gz
PGS002115
(portability-ldpred2_drink_alcohol)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Alcohol drinker status alcohol drinking 766,714
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002115/ScoringFiles/PGS002115.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010091 PGS001901
(portability-PLR_drink_alcohol)
PSS009398|
European Ancestry|
19,294 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0209 [0.0068, 0.035] sex, age, birth date, deprivation index, 16 PCs
PPM010092 PGS001901
(portability-PLR_drink_alcohol)
PSS009172|
European Ancestry|
3,938 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0195 [-0.0118, 0.0508] sex, age, birth date, deprivation index, 16 PCs
PPM010093 PGS001901
(portability-PLR_drink_alcohol)
PSS008726|
European Ancestry|
6,413 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0217 [-0.0028, 0.0462] sex, age, birth date, deprivation index, 16 PCs
PPM010094 PGS001901
(portability-PLR_drink_alcohol)
PSS008500|
Greater Middle Eastern Ancestry|
1,101 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0069 [-0.0527, 0.0665] sex, age, birth date, deprivation index, 16 PCs
PPM010095 PGS001901
(portability-PLR_drink_alcohol)
PSS008278|
South Asian Ancestry|
5,830 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0024 [-0.0233, 0.0281] sex, age, birth date, deprivation index, 16 PCs
PPM010096 PGS001901
(portability-PLR_drink_alcohol)
PSS008055|
East Asian Ancestry|
1,726 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0204 [-0.0271, 0.0678] sex, age, birth date, deprivation index, 16 PCs
PPM010097 PGS001901
(portability-PLR_drink_alcohol)
PSS007842|
African Ancestry|
2,357 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0195 [-0.021, 0.06] sex, age, birth date, deprivation index, 16 PCs
PPM010098 PGS001901
(portability-PLR_drink_alcohol)
PSS008946|
African Ancestry|
3,609 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0279 [-0.0048, 0.0606] sex, age, birth date, deprivation index, 16 PCs
PPM011775 PGS002115
(portability-ldpred2_drink_alcohol)
PSS009398|
European Ancestry|
19,294 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0284 [0.0143, 0.0425] sex, age, birth date, deprivation index, 16 PCs
PPM011776 PGS002115
(portability-ldpred2_drink_alcohol)
PSS009172|
European Ancestry|
3,938 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0691 [0.0379, 0.1002] sex, age, birth date, deprivation index, 16 PCs
PPM011777 PGS002115
(portability-ldpred2_drink_alcohol)
PSS008726|
European Ancestry|
6,413 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0566 [0.0321, 0.081] sex, age, birth date, deprivation index, 16 PCs
PPM011778 PGS002115
(portability-ldpred2_drink_alcohol)
PSS008500|
Greater Middle Eastern Ancestry|
1,101 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0437 [-0.016, 0.1031] sex, age, birth date, deprivation index, 16 PCs
PPM011779 PGS002115
(portability-ldpred2_drink_alcohol)
PSS008278|
South Asian Ancestry|
5,830 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0014 [-0.0243, 0.0271] sex, age, birth date, deprivation index, 16 PCs
PPM011780 PGS002115
(portability-ldpred2_drink_alcohol)
PSS008055|
East Asian Ancestry|
1,726 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.02 [-0.0275, 0.0674] sex, age, birth date, deprivation index, 16 PCs
PPM011781 PGS002115
(portability-ldpred2_drink_alcohol)
PSS007842|
African Ancestry|
2,357 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0094 [-0.0311, 0.0499] sex, age, birth date, deprivation index, 16 PCs
PPM011782 PGS002115
(portability-ldpred2_drink_alcohol)
PSS008946|
African Ancestry|
3,609 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status Partial Correlation (partial-r): 0.0434 [0.0107, 0.076] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008946 3,609 individuals African unspecified Nigeria (West Africa) UKB
PSS009172 3,938 individuals European Poland (NE Europe) UKB
PSS008500 1,101 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009398 19,294 individuals European UK (+ Ireland) UKB
PSS008726 6,413 individuals European Italy (South Europe) UKB
PSS008278 5,830 individuals South Asian India (South Asia) UKB
PSS008055 1,726 individuals East Asian China (East Asia) UKB
PSS007842 2,357 individuals African American or Afro-Caribbean Carribean UKB