| Experimental Factor Ontology (EFO) Information | |
| Identifier | EFO_0004736 |
| Description | Is a quantification of aspartate aminotransferase, and is commonly used as a marker for liver function. | Trait category |
Other measurement
|
| Synonym | Aspartate transaminase measurement |
| Mapped terms |
2 mapped terms
|
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS000673 (snpnet.Aspartate_aminotransferase) |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
Aspartate aminotransferase [U/L] | aspartate aminotransferase measurement | 12,829 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000673/ScoringFiles/PGS000673.txt.gz |
| PGS001941 (portability-PLR_log_AST) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Aspartate aminotransferase level | aspartate aminotransferase measurement | 33,498 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001941/ScoringFiles/PGS001941.txt.gz |
| PGS002159 (portability-ldpred2_log_AST) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Aspartate aminotransferase level | aspartate aminotransferase measurement | 716,914 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002159/ScoringFiles/PGS002159.txt.gz |
| PGS003343 (CVGRS_AST) |
PGP000405 | Kim YJ et al. Nat Commun (2022) |
Aspartate aminotransferase level | aspartate aminotransferase measurement | 54 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003343/ScoringFiles/PGS003343.txt.gz |
| PGS003352 (ALLGRS_AST) |
PGP000405 | Kim YJ et al. Nat Commun (2022) |
Aspartate aminotransferase level | aspartate aminotransferase measurement | 56 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003352/ScoringFiles/PGS003352.txt.gz |
| PGS003523 (cont-decay-log_AST) |
PGP000457 | Ding Y et al. Nature (2023) |
Aspartate aminotransferase level | aspartate aminotransferase measurement | 979,739 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003523/ScoringFiles/PGS003523.txt.gz |
| PGS004330 (X30650.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
Aspartate aminotransferase (U/L) | aspartate aminotransferase measurement | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004330/ScoringFiles/PGS004330.txt.gz |
| PGS004719 (AST_PRSmix_eur) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Aspartate aminotransferase level | aspartate aminotransferase measurement | 519,241 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004719/ScoringFiles/PGS004719.txt.gz |
| PGS004720 (AST_PRSmix_sas) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Aspartate aminotransferase level | aspartate aminotransferase measurement | 1,000,300 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004720/ScoringFiles/PGS004720.txt.gz |
| PGS004721 (AST_PRSmixPlus_eur) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Aspartate aminotransferase level | aspartate aminotransferase measurement | 1,196,185 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004721/ScoringFiles/PGS004721.txt.gz |
| PGS004722 (AST_PRSmixPlus_sas) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Aspartate aminotransferase level | aspartate aminotransferase measurement | 868,009 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004722/ScoringFiles/PGS004722.txt.gz |
| PGS019788 (TPMI_AST_Lassosum2) |
PGP000835 | Chen HH et al. Nature (2025) |
Serum glutamic oxaloacetic transaminase | aspartate aminotransferase measurement | 12,139 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019788/ScoringFiles/PGS019788.txt.gz | |
| PGS019812 (TPMI_AST_LDPred2) |
PGP000835 | Chen HH et al. Nature (2025) |
Serum glutamic oxaloacetic transaminase | aspartate aminotransferase measurement | 939,795 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019812/ScoringFiles/PGS019812.txt.gz | |
| PGS019836 (TPMI_AST_PRS-CS) |
PGP000835 | Chen HH et al. Nature (2025) |
Serum glutamic oxaloacetic transaminase | aspartate aminotransferase measurement | 983,751 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019836/ScoringFiles/PGS019836.txt.gz | |
| PGS019860 (TPMI_AST_SBayesR) |
PGP000835 | Chen HH et al. Nature (2025) |
Serum glutamic oxaloacetic transaminase | aspartate aminotransferase measurement | 190,635 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019860/ScoringFiles/PGS019860.txt.gz | |
| PGS019884 (TPMI_AST_MegaPRS) |
PGP000835 | Chen HH et al. Nature (2025) |
Serum glutamic oxaloacetic transaminase | aspartate aminotransferase measurement | 373,694 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019884/ScoringFiles/PGS019884.txt.gz |
|
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM001436 | PGS000673 (snpnet.Aspartate_aminotransferase) |
PSS000648| East Asian Ancestry| 1,070 individuals |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
Reported Trait: Aspartate aminotransferase [U/L] | — | — | R²: 0.08343 Spearman's ρ: 0.191 |
Age, sex, PCs(1-40) | — |
| PPM001401 | PGS000673 (snpnet.Aspartate_aminotransferase) |
PSS000647| African Ancestry| 5,982 individuals |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
Reported Trait: Aspartate aminotransferase [U/L] | — | — | R²: 0.10334 Spearman's ρ: 0.103 |
Age, sex, PCs(1-40) | — |
| PPM001506 | PGS000673 (snpnet.Aspartate_aminotransferase) |
PSS000650| South Asian Ancestry| 7,313 individuals |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
Reported Trait: Aspartate aminotransferase [U/L] | — | — | R²: 0.11262 Spearman's ρ: 0.243 |
Age, sex, PCs(1-40) | — |
| PPM001541 | PGS000673 (snpnet.Aspartate_aminotransferase) |
PSS000651| European Ancestry| 63,562 individuals |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
Reported Trait: Aspartate aminotransferase [U/L] | — | — | R²: 0.1493 Spearman's ρ: 0.285 |
Age, sex, PCs(1-40) | — |
| PPM001471 | PGS000673 (snpnet.Aspartate_aminotransferase) |
PSS000649| European Ancestry| 23,483 individuals |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
Reported Trait: Aspartate aminotransferase [U/L] | — | — | R²: 0.1564 Spearman's ρ: 0.278 |
Age, sex, PCs(1-40) | — |
| PPM007290 | PGS000673 (snpnet.Aspartate_aminotransferase) |
PSS007106| African Ancestry| 6,063 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |Ext. |
Reported Trait: Aspartate aminotransferase | — | — | R²: 0.03615 [0.02724, 0.04506] Incremental R2 (full-covars): 0.00048 PGS R2 (no covariates): 0.0043 [0.00113, 0.00747] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007291 | PGS000673 (snpnet.Aspartate_aminotransferase) |
PSS007107| East Asian Ancestry| 1,604 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |Ext. |
Reported Trait: Aspartate aminotransferase | — | — | R²: 0.01565 [0.00398, 0.02731] Incremental R2 (full-covars): 0.00093 PGS R2 (no covariates): 0.01452 [0.00327, 0.02577] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007292 | PGS000673 (snpnet.Aspartate_aminotransferase) |
PSS007108| European Ancestry| 23,673 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |Ext. |
Reported Trait: Aspartate aminotransferase | — | — | R²: 0.04146 [0.03661, 0.04631] Incremental R2 (full-covars): 0.00197 PGS R2 (no covariates): 0.02948 [0.02534, 0.03362] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007293 | PGS000673 (snpnet.Aspartate_aminotransferase) |
PSS007109| South Asian Ancestry| 7,402 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |Ext. |
Reported Trait: Aspartate aminotransferase | — | — | R²: 0.03584 [0.02776, 0.04393] Incremental R2 (full-covars): 0.00195 PGS R2 (no covariates): 0.02928 [0.02192, 0.03663] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007294 | PGS000673 (snpnet.Aspartate_aminotransferase) |
PSS007110| European Ancestry| 64,238 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |Ext. |
Reported Trait: Aspartate aminotransferase | — | — | R²: 0.03244 [0.02981, 0.03507] Incremental R2 (full-covars): 0.00218 PGS R2 (no covariates): 0.03087 [0.0283, 0.03344] |
age, sex, UKB array type, Genotype PCs | — |
| PPM010403 | PGS001941 (portability-PLR_log_AST) |
PSS009428| European Ancestry| 18,929 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.2685 [0.2552, 0.2816] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010404 | PGS001941 (portability-PLR_log_AST) |
PSS009202| European Ancestry| 3,933 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.2451 [0.2154, 0.2743] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010405 | PGS001941 (portability-PLR_log_AST) |
PSS008756| European Ancestry| 6,307 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.2543 [0.231, 0.2773] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010406 | PGS001941 (portability-PLR_log_AST) |
PSS008530| Greater Middle Eastern Ancestry| 1,124 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.2157 [0.1587, 0.2713] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010407 | PGS001941 (portability-PLR_log_AST) |
PSS008308| South Asian Ancestry| 5,980 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.2288 [0.2046, 0.2527] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010408 | PGS001941 (portability-PLR_log_AST) |
PSS008085| East Asian Ancestry| 1,703 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.1846 [0.138, 0.2303] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010409 | PGS001941 (portability-PLR_log_AST) |
PSS007872| African Ancestry| 2,330 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.1077 [0.0672, 0.1478] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010410 | PGS001941 (portability-PLR_log_AST) |
PSS008976| African Ancestry| 3,640 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.0657 [0.0332, 0.098] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012119 | PGS002159 (portability-ldpred2_log_AST) |
PSS009428| European Ancestry| 18,929 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.2679 [0.2546, 0.2811] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012120 | PGS002159 (portability-ldpred2_log_AST) |
PSS009202| European Ancestry| 3,933 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.2333 [0.2034, 0.2627] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012121 | PGS002159 (portability-ldpred2_log_AST) |
PSS008756| European Ancestry| 6,307 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.2564 [0.2332, 0.2794] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012122 | PGS002159 (portability-ldpred2_log_AST) |
PSS008530| Greater Middle Eastern Ancestry| 1,124 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.2194 [0.1625, 0.2749] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012123 | PGS002159 (portability-ldpred2_log_AST) |
PSS008308| South Asian Ancestry| 5,980 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.2225 [0.1982, 0.2465] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012125 | PGS002159 (portability-ldpred2_log_AST) |
PSS007872| African Ancestry| 2,330 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.1083 [0.0678, 0.1484] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012126 | PGS002159 (portability-ldpred2_log_AST) |
PSS008976| African Ancestry| 3,640 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.0633 [0.0308, 0.0957] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012124 | PGS002159 (portability-ldpred2_log_AST) |
PSS008085| East Asian Ancestry| 1,703 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Aspartate aminotransferase | — | — | Partial Correlation (partial-r): 0.183 [0.1364, 0.2288] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM016182 | PGS003343 (CVGRS_AST) |
PSS010055| East Asian Ancestry| 22,608 individuals |
PGP000405 | Kim YJ et al. Nat Commun (2022) |
Reported Trait: Aspartate aminotransferase level | β: 0.13654 | — | — | — | — |
| PPM016199 | PGS003343 (CVGRS_AST) |
PSS010055| East Asian Ancestry| 22,608 individuals |
PGP000405 | Kim YJ et al. Nat Commun (2022) |
Reported Trait: Type 2 diabetes | OR: 0.99256 | — | — | — | — |
| PPM016191 | PGS003352 (ALLGRS_AST) |
PSS010055| East Asian Ancestry| 22,608 individuals |
PGP000405 | Kim YJ et al. Nat Commun (2022) |
Reported Trait: Aspartate aminotransferase level | β: 0.14314 | — | — | — | — |
| PPM017451 | PGS003523 (cont-decay-log_AST) |
PSS010886| European Ancestry| 19,052 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: Aspartate aminotransferase | — | — | partial-R2: 0.07 | sex, age, deprivation index, PC1-16 | — |
| PPM017535 | PGS003523 (cont-decay-log_AST) |
PSS010802| European Ancestry| 3,922 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: Aspartate aminotransferase | — | — | partial-R2: 0.05 | sex, age, deprivation index, PC1-16 | — |
| PPM017703 | PGS003523 (cont-decay-log_AST) |
PSS010550| Greater Middle Eastern Ancestry| 1,095 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: Aspartate aminotransferase | — | — | partial-R2: 0.06 | sex, age, deprivation index, PC1-16 | — |
| PPM017871 | PGS003523 (cont-decay-log_AST) |
PSS010466| South Asian Ancestry| 5,926 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: Aspartate aminotransferase | — | — | partial-R2: 0.05 | sex, age, deprivation index, PC1-16 | — |
| PPM017955 | PGS003523 (cont-decay-log_AST) |
PSS010382| East Asian Ancestry| 1,692 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: Aspartate aminotransferase | — | — | partial-R2: 0.03 | sex, age, deprivation index, PC1-16 | — |
| PPM018039 | PGS003523 (cont-decay-log_AST) |
PSS010298| African Ancestry| 2,318 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: Aspartate aminotransferase | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
| PPM017619 | PGS003523 (cont-decay-log_AST) |
PSS010634| European Ancestry| 6,155 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: Aspartate aminotransferase | — | — | partial-R2: 0.07 | sex, age, deprivation index, PC1-16 | — |
| PPM017787 | PGS003523 (cont-decay-log_AST) |
PSS010214| European Ancestry| 2,233 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: Aspartate aminotransferase | — | — | partial-R2: 0.09 | sex, age, deprivation index, PC1-16 | — |
| PPM018123 | PGS003523 (cont-decay-log_AST) |
PSS010718| African Ancestry| 3,611 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: Aspartate aminotransferase | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
| PPM020445 | PGS004330 (X30650.score) |
PSS011364| European Ancestry| 56,192 individuals |
PGP000561 | Jung H et al. Commun Biol (2024) |
Reported Trait: Aspartate aminotransferase (U/L) | — | — | PGS R2 (no covariates): 0.18813 | — | — |
| PPM020944 | PGS004719 (AST_PRSmix_eur) |
PSS011481| European Ancestry| 4,728 individuals |
PGP000604 | Truong B et al. Cell Genom (2024) |
Reported Trait: Aspartate aminotransferase | — | — | Incremental R2 (Full model versus model with only covariates): 0.012 [0.006, 0.018] | age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 | Incremental R2 (Full model versus model with only covariates) |
| PPM020945 | PGS004720 (AST_PRSmix_sas) |
PSS011459| South Asian Ancestry| 2,710 individuals |
PGP000604 | Truong B et al. Cell Genom (2024) |
Reported Trait: Aspartate aminotransferase | — | — | Incremental R2 (Full model versus model with only covariates): 0.03 [0.017, 0.042] | age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 | Incremental R2 (Full model versus model with only covariates) |
| PPM020946 | PGS004721 (AST_PRSmixPlus_eur) |
PSS011481| European Ancestry| 4,728 individuals |
PGP000604 | Truong B et al. Cell Genom (2024) |
Reported Trait: Aspartate aminotransferase | — | — | Incremental R2 (Full model versus model with only covariates): 0.034 [0.024, 0.044] | age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 | Incremental R2 (Full model versus model with only covariates) |
| PPM020947 | PGS004722 (AST_PRSmixPlus_sas) |
PSS011459| South Asian Ancestry| 2,710 individuals |
PGP000604 | Truong B et al. Cell Genom (2024) |
Reported Trait: Aspartate aminotransferase | — | — | Incremental R2 (Full model versus model with only covariates): 0.03 [0.017, 0.042] | age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 | Incremental R2 (Full model versus model with only covariates) |
| PPM037970 | PGS019788 (TPMI_AST_Lassosum2) |
PSS013696| East Asian Ancestry| 11,300 individuals |
PGP000835 | Chen HH et al. Nature (2025) |
Reported Trait: Serum glutamic oxaloacetic transaminase | — | AUROC: 0.5573 | R²: 0.02593 | sex, age, array, PCs 1-10 | — |
| PPM037994 | PGS019812 (TPMI_AST_LDPred2) |
PSS013695| East Asian Ancestry| 11,300 individuals |
PGP000835 | Chen HH et al. Nature (2025) |
Reported Trait: Serum glutamic oxaloacetic transaminase | — | AUROC: 0.77815 | R²: 0.03035 | sex, age, array, PCs 1-10 | — |
| PPM038018 | PGS019836 (TPMI_AST_PRS-CS) |
PSS013698| East Asian Ancestry| 11,300 individuals |
PGP000835 | Chen HH et al. Nature (2025) |
Reported Trait: Serum glutamic oxaloacetic transaminase | — | AUROC: 0.73716 | R²: 0.03123 | sex, age, array, PCs 1-10 | — |
| PPM038042 | PGS019860 (TPMI_AST_SBayesR) |
PSS013699| East Asian Ancestry| 11,300 individuals |
PGP000835 | Chen HH et al. Nature (2025) |
Reported Trait: Serum glutamic oxaloacetic transaminase | — | — | R²: 0.02275 | sex, age, array, PCs 1-10 | — |
| PPM038066 | PGS019884 (TPMI_AST_MegaPRS) |
PSS013697| East Asian Ancestry| 11,300 individuals |
PGP000835 | Chen HH et al. Nature (2025) |
Reported Trait: Serum glutamic oxaloacetic transaminase | — | — | R²: 0.0292 | sex, age, array, PCs 1-10 | — |
|
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS013695 | — | — | 11,300 individuals, 46.44 % Male samples |
— | East Asian (Han Chinese) |
— | TPMI | — |
| PSS013696 | — | — | 11,300 individuals, 46.44 % Male samples |
— | East Asian (Han Chinese) |
— | TPMI | — |
| PSS013697 | — | — | 11,300 individuals, 46.44 % Male samples |
— | East Asian (Han Chinese) |
— | TPMI | — |
| PSS013698 | — | — | 11,300 individuals, 46.44 % Male samples |
— | East Asian (Han Chinese) |
— | TPMI | — |
| PSS007106 | — | — | 6,063 individuals | — | African unspecified | — | UKB | — |
| PSS007107 | — | — | 1,604 individuals | — | East Asian | — | UKB | — |
| PSS007108 | — | — | 23,673 individuals | — | European | non-white British ancestry | UKB | — |
| PSS007109 | — | — | 7,402 individuals | — | South Asian | — | UKB | — |
| PSS007110 | — | — | 64,238 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS013699 | — | — | 11,300 individuals, 46.44 % Male samples |
— | East Asian (Han Chinese) |
— | TPMI | — |
| PSS008530 | — | — | 1,124 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS009428 | — | — | 18,929 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS010055 | — | — | 22,608 individuals | — | East Asian | — | KBA, KoGES | — |
| PSS011459 | — | — | 2,710 individuals | — | South Asian | — | G&H | — |
| PSS010802 | — | — | 3,922 individuals, 38.0 % Male samples |
Mean = 54.4 years Sd = 7.5 years |
European | Polish | UKB | — |
| PSS010550 | — | — | 1,095 individuals, 60.0 % Male samples |
Mean = 51.9 years Sd = 7.9 years |
Greater Middle Eastern (Middle Eastern, North African or Persian) | Iranian | UKB | — |
| PSS010298 | — | — | 2,318 individuals, 37.0 % Male samples |
Mean = 52.5 years Sd = 8.1 years |
African American or Afro-Caribbean | Caribbean | UKB | — |
| PSS011481 | — | — | 4,728 individuals | — | European | — | AllofUs | — |
| PSS009202 | — | — | 3,933 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS008308 | — | — | 5,980 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS010718 | — | — | 3,611 individuals, 46.0 % Male samples |
Mean = 51.9 years Sd = 8.1 years |
African unspecified | Nigerian | UKB | — |
| PSS010466 | — | — | 5,926 individuals, 54.0 % Male samples |
Mean = 53.3 years Sd = 8.4 years |
South Asian | Indian | UKB | — |
| PSS010214 | — | — | 2,233 individuals, 45.0 % Male samples |
Mean = 58.1 years Sd = 7.1 years |
European | Ashkenazi | UKB | — |
| PSS008976 | — | — | 3,640 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS008085 | — | — | 1,703 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS011364 | — | — | 56,192 individuals | — | European | — | UKB | — |
| PSS000647 | — | — | 5,982 individuals | — | African unspecified | — | UKB | — |
| PSS000648 | — | — | 1,070 individuals | — | East Asian | — | UKB | — |
| PSS000649 | — | — | 23,483 individuals | — | European | Non-British White | UKB | — |
| PSS000650 | — | — | 7,313 individuals | — | South Asian | — | UKB | — |
| PSS000651 | — | — | 63,562 individuals | — | European (British) |
— | UKB | — |
| PSS010886 | — | — | 19,052 individuals, 46.0 % Male samples |
Mean = 56.9 years Sd = 7.9 years |
European | white British | UKB | — |
| PSS010634 | — | — | 6,155 individuals, 45.0 % Male samples |
Mean = 54.5 years Sd = 8.4 years |
European | Italian | UKB | — |
| PSS008756 | — | — | 6,307 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS010382 | — | — | 1,692 individuals, 34.0 % Male samples |
Mean = 52.4 years Sd = 7.8 years |
East Asian | Chinese | UKB | — |
| PSS007872 | — | — | 2,330 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |