Trait: neutrophil count

Experimental Factor Ontology (EFO) Information
Identifier EFO_0004833
Description
  • The number of granulocytes (polymorphonuclear leukocytes) in a specified volume of blood, usually 1 cubic millimeter.
  • Is a quantification of neutrophils in blood.
Trait category
Hematological measurement
Synonym blood neutrophil count
Mapped terms 4 mapped terms
  • CMO:0000030
  • MedDRA:10029363
  • NCIt:C51950
  • SNOMEDCT:30630007
Child trait(s) neutrophil percentage of leukocytes

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "neutrophil count" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS000105
(neut)
 PGP000051 |
Xu Y et al. Cell Genom (2022)
 Neutrophil count neutrophil count 23,864
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000105/ScoringFiles/PGS000105.txt.gz
PGS000106
(neut_p)
 PGP000051 |
Xu Y et al. Cell Genom (2022)
 Neutrophil percentage of white cells neutrophil percentage of leukocytes 22,049
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000106/ScoringFiles/PGS000106.txt.gz
PGS000182
(neut)
 PGP000078 |
Vuckovic D et al. Cell (2020)
 Neutrophil count neutrophil count 492
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000182/ScoringFiles/PGS000182.txt.gz
PGS000183
(neut_p)
 PGP000078 |
Vuckovic D et al. Cell (2020)
 Neutrophil percentage of white cells neutrophil percentage of leukocytes 437
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000183/ScoringFiles/PGS000183.txt.gz
PGS001077
(GBE_INI30200)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Neutrophill % neutrophil percentage of leukocytes 13,703
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001077/ScoringFiles/PGS001077.txt.gz
PGS001173
(GBE_INI30140)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Neutrophill count neutrophil count 15,578
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001173/ScoringFiles/PGS001173.txt.gz
PGS001969
(portability-PLR_log_neutrophil)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Neutrophil count neutrophil count 71,566
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001969/ScoringFiles/PGS001969.txt.gz
PGS001997
(portability-PLR_neutrophil_perc)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Neutrophil percentage neutrophil percentage of leukocytes 65,022
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001997/ScoringFiles/PGS001997.txt.gz
PGS002187
(portability-ldpred2_log_neutrophil)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Neutrophil count neutrophil count 803,767
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002187/ScoringFiles/PGS002187.txt.gz
PGS002214
(portability-ldpred2_neutrophil_perc)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Neutrophil percentage neutrophil percentage of leukocytes 769,542
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002214/ScoringFiles/PGS002214.txt.gz
PGS003545
(cont-decay-log_neutrophil)
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Neutrophil count neutrophil count 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003545/ScoringFiles/PGS003545.txt.gz
PGS003566
(cont-decay-neutrophil_perc)
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Neutrophil percentage neutrophil percentage of leukocytes 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003566/ScoringFiles/PGS003566.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000242 PGS000105
(neut)
 PSS000170|
European Ancestry|
81,358 individuals
 PGP000051 |
Xu Y et al. Cell Genom (2022)
 Reported Trait: Neutrophil count — — Pearson correlation coefficent (r): 0.36386 age, sex, 10 PCs of ancestry, lifestyle factors (diet, smoking, alcohol consumption), technical covariates (the time between venepuncture and full blood cell analysis, seasonal effects, centre of sample collection, time dependent drift of equipment, systematic differences in equipment) UKB Testing Set - these samples were held out from Score Development (regression training) but overlap with the samples used for variant selection (GWAS)
PPM000243 PGS000105
(neut)
 PSS000144|
European Ancestry|
39,138 individuals
 PGP000051 |
Xu Y et al. Cell Genom (2022)
 Reported Trait: Neutrophil count — — Pearson correlation coefficent (r): 0.35194 age, sex, 10 PCs of ancestry, lifestyle factors (diet, smoking, alcohol consumption), technical covariates (the time between venepuncture and full blood cell analysis, seasonal effects, centre of sample collection, time dependent drift of equipment, systematic differences in equipment) —
PPM000244 PGS000106
(neut_p)
 PSS000171|
European Ancestry|
81,423 individuals
 PGP000051 |
Xu Y et al. Cell Genom (2022)
 Reported Trait: Neutrophil percentage of white cells — — Pearson correlation coefficent (r): 0.32169 age, sex, 10 PCs of ancestry, lifestyle factors (diet, smoking, alcohol consumption), technical covariates (the time between venepuncture and full blood cell analysis, seasonal effects, centre of sample collection, time dependent drift of equipment, systematic differences in equipment) UKB Testing Set - these samples were held out from Score Development (regression training) but overlap with the samples used for variant selection (GWAS)
PPM000245 PGS000106
(neut_p)
 PSS000145|
European Ancestry|
39,190 individuals
 PGP000051 |
Xu Y et al. Cell Genom (2022)
 Reported Trait: Neutrophil percentage of white cells — — Pearson correlation coefficent (r): 0.31935 age, sex, 10 PCs of ancestry, lifestyle factors (diet, smoking, alcohol consumption), technical covariates (the time between venepuncture and full blood cell analysis, seasonal effects, centre of sample collection, time dependent drift of equipment, systematic differences in equipment) —
PPM000556 PGS000182
(neut)
 PSS000290|
European Ancestry|
2,314 individuals
 PGP000078 |
Vuckovic D et al. Cell (2020)
 Reported Trait: Neutrophil count — — R²: 0.06859 sex, age, 10 genetic PCs —
PPM000536 PGS000182
(neut)
 PSS000291|
European Ancestry|
39,260 individuals
 PGP000078 |
Vuckovic D et al. Cell (2020)
 Reported Trait: Neutrophil count — — R²: 0.08009 sex, age, 10 genetic PCs —
PPM000537 PGS000183
(neut_p)
 PSS000291|
European Ancestry|
39,260 individuals
 PGP000078 |
Vuckovic D et al. Cell (2020)
 Reported Trait: Neutrophil percentage of white cells — — R²: 0.06432 sex, age, 10 genetic PCs —
PPM008143 PGS001077
(GBE_INI30200)
 PSS007001|
African Ancestry|
6,120 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Neutrophill % — — Incremental R2 (full-covars): 0.01344
R²: 0.04156 [0.03206, 0.05106]
PGS R2 (no covariates): 0.01383 [0.00819, 0.01946]		 age, sex, UKB array type, Genotype PCs —
PPM008144 PGS001077
(GBE_INI30200)
 PSS007002|
East Asian Ancestry|
1,654 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Neutrophill % — — R²: 0.07662 [0.0524, 0.10084]
Incremental R2 (full-covars): 0.04345
PGS R2 (no covariates): 0.04564 [0.02632, 0.06496]		 age, sex, UKB array type, Genotype PCs —
PPM008145 PGS001077
(GBE_INI30200)
 PSS007003|
European Ancestry|
24,130 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Neutrophill % — — R²: 0.07418 [0.06792, 0.08044]
Incremental R2 (full-covars): 0.07151
PGS R2 (no covariates): 0.07289 [0.06667, 0.0791]		 age, sex, UKB array type, Genotype PCs —
PPM008146 PGS001077
(GBE_INI30200)
 PSS007004|
South Asian Ancestry|
7,491 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Neutrophill % — — R²: 0.05036 [0.04093, 0.0598]
Incremental R2 (full-covars): 0.04554
PGS R2 (no covariates): 0.04441 [0.03549, 0.05333]		 age, sex, UKB array type, Genotype PCs —
PPM008147 PGS001077
(GBE_INI30200)
 PSS007005|
European Ancestry|
65,520 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Neutrophill % — — R²: 0.08175 [0.07779, 0.08572]
Incremental R2 (full-covars): 0.07935
PGS R2 (no covariates): 0.07934 [0.07542, 0.08325]		 age, sex, UKB array type, Genotype PCs —
PPM008575 PGS001173
(GBE_INI30140)
 PSS006976|
African Ancestry|
6,120 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Neutrophill count — — R²: 0.06347 [0.052, 0.07494]
Incremental R2 (full-covars): 0.00644
PGS R2 (no covariates): 0.01221 [0.00691, 0.01752]		 age, sex, UKB array type, Genotype PCs —
PPM008576 PGS001173
(GBE_INI30140)
 PSS006977|
East Asian Ancestry|
1,654 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Neutrophill count — — R²: 0.05754 [0.03611, 0.07896]
Incremental R2 (full-covars): 0.037
PGS R2 (no covariates): 0.0354 [0.0182, 0.0526]		 age, sex, UKB array type, Genotype PCs —
PPM008577 PGS001173
(GBE_INI30140)
 PSS006978|
European Ancestry|
24,129 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Neutrophill count — — R²: 0.08794 [0.08123, 0.09466]
Incremental R2 (full-covars): 0.07899
PGS R2 (no covariates): 0.08282 [0.07627, 0.08938]		 age, sex, UKB array type, Genotype PCs —
PPM008578 PGS001173
(GBE_INI30140)
 PSS006979|
South Asian Ancestry|
7,491 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Neutrophill count — — R²: 0.07553 [0.06428, 0.08677]
Incremental R2 (full-covars): 0.0671
PGS R2 (no covariates): 0.06762 [0.05688, 0.07835]		 age, sex, UKB array type, Genotype PCs —
PPM008579 PGS001173
(GBE_INI30140)
 PSS006980|
European Ancestry|
65,520 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Neutrophill count — — R²: 0.09385 [0.08966, 0.09804]
Incremental R2 (full-covars): 0.08871
PGS R2 (no covariates): 0.08935 [0.08524, 0.09346]		 age, sex, UKB array type, Genotype PCs —
PPM010629 PGS001969
(portability-PLR_log_neutrophil)
 PSS008786|
European Ancestry|
6,419 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.3157 [0.2934, 0.3376] sex, age, birth date, deprivation index, 16 PCs —
PPM010627 PGS001969
(portability-PLR_log_neutrophil)
 PSS009458|
European Ancestry|
19,382 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.3305 [0.3179, 0.343] sex, age, birth date, deprivation index, 16 PCs —
PPM010628 PGS001969
(portability-PLR_log_neutrophil)
 PSS009232|
European Ancestry|
3,992 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.3137 [0.2853, 0.3414] sex, age, birth date, deprivation index, 16 PCs —
PPM010631 PGS001969
(portability-PLR_log_neutrophil)
 PSS008338|
South Asian Ancestry|
6,060 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.2983 [0.2751, 0.3211] sex, age, birth date, deprivation index, 16 PCs —
PPM010632 PGS001969
(portability-PLR_log_neutrophil)
 PSS008115|
East Asian Ancestry|
1,761 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.2374 [0.1926, 0.2813] sex, age, birth date, deprivation index, 16 PCs —
PPM010633 PGS001969
(portability-PLR_log_neutrophil)
 PSS007902|
African Ancestry|
2,336 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.1856 [0.146, 0.2246] sex, age, birth date, deprivation index, 16 PCs —
PPM010634 PGS001969
(portability-PLR_log_neutrophil)
 PSS009006|
African Ancestry|
3,697 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.1384 [0.1066, 0.17] sex, age, birth date, deprivation index, 16 PCs —
PPM010630 PGS001969
(portability-PLR_log_neutrophil)
 PSS008560|
Greater Middle Eastern Ancestry|
1,149 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.267 [0.212, 0.3204] sex, age, birth date, deprivation index, 16 PCs —
PPM010852 PGS001997
(portability-PLR_neutrophil_perc)
 PSS009254|
European Ancestry|
3,988 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.2971 [0.2684, 0.3252] sex, age, birth date, deprivation index, 16 PCs —
PPM010853 PGS001997
(portability-PLR_neutrophil_perc)
 PSS008808|
European Ancestry|
6,413 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.2972 [0.2747, 0.3194] sex, age, birth date, deprivation index, 16 PCs —
PPM010854 PGS001997
(portability-PLR_neutrophil_perc)
 PSS008582|
Greater Middle Eastern Ancestry|
1,147 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.2921 [0.2377, 0.3446] sex, age, birth date, deprivation index, 16 PCs —
PPM010855 PGS001997
(portability-PLR_neutrophil_perc)
 PSS008360|
South Asian Ancestry|
6,055 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.2672 [0.2436, 0.2904] sex, age, birth date, deprivation index, 16 PCs —
PPM010856 PGS001997
(portability-PLR_neutrophil_perc)
 PSS008137|
East Asian Ancestry|
1,760 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.2332 [0.1882, 0.2771] sex, age, birth date, deprivation index, 16 PCs —
PPM010857 PGS001997
(portability-PLR_neutrophil_perc)
 PSS007924|
African Ancestry|
2,334 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.166 [0.1261, 0.2054] sex, age, birth date, deprivation index, 16 PCs —
PPM010858 PGS001997
(portability-PLR_neutrophil_perc)
 PSS009028|
African Ancestry|
3,681 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.1587 [0.1269, 0.1901] sex, age, birth date, deprivation index, 16 PCs —
PPM010851 PGS001997
(portability-PLR_neutrophil_perc)
 PSS009480|
European Ancestry|
19,359 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.3059 [0.293, 0.3186] sex, age, birth date, deprivation index, 16 PCs —
PPM012343 PGS002187
(portability-ldpred2_log_neutrophil)
 PSS009458|
European Ancestry|
19,382 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.3263 [0.3137, 0.3388] sex, age, birth date, deprivation index, 16 PCs —
PPM012344 PGS002187
(portability-ldpred2_log_neutrophil)
 PSS009232|
European Ancestry|
3,992 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.3117 [0.2834, 0.3395] sex, age, birth date, deprivation index, 16 PCs —
PPM012345 PGS002187
(portability-ldpred2_log_neutrophil)
 PSS008786|
European Ancestry|
6,419 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.3147 [0.2924, 0.3366] sex, age, birth date, deprivation index, 16 PCs —
PPM012346 PGS002187
(portability-ldpred2_log_neutrophil)
 PSS008560|
Greater Middle Eastern Ancestry|
1,149 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.2709 [0.2159, 0.3241] sex, age, birth date, deprivation index, 16 PCs —
PPM012347 PGS002187
(portability-ldpred2_log_neutrophil)
 PSS008338|
South Asian Ancestry|
6,060 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.3015 [0.2784, 0.3242] sex, age, birth date, deprivation index, 16 PCs —
PPM012348 PGS002187
(portability-ldpred2_log_neutrophil)
 PSS008115|
East Asian Ancestry|
1,761 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.2401 [0.1953, 0.2839] sex, age, birth date, deprivation index, 16 PCs —
PPM012349 PGS002187
(portability-ldpred2_log_neutrophil)
 PSS007902|
African Ancestry|
2,336 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.1884 [0.1488, 0.2274] sex, age, birth date, deprivation index, 16 PCs —
PPM012350 PGS002187
(portability-ldpred2_log_neutrophil)
 PSS009006|
African Ancestry|
3,697 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil count — — Partial Correlation (partial-r): 0.1552 [0.1235, 0.1866] sex, age, birth date, deprivation index, 16 PCs —
PPM012559 PGS002214
(portability-ldpred2_neutrophil_perc)
 PSS009480|
European Ancestry|
19,359 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.3042 [0.2913, 0.3169] sex, age, birth date, deprivation index, 16 PCs —
PPM012560 PGS002214
(portability-ldpred2_neutrophil_perc)
 PSS009254|
European Ancestry|
3,988 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.2993 [0.2707, 0.3274] sex, age, birth date, deprivation index, 16 PCs —
PPM012561 PGS002214
(portability-ldpred2_neutrophil_perc)
 PSS008808|
European Ancestry|
6,413 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.2906 [0.268, 0.3129] sex, age, birth date, deprivation index, 16 PCs —
PPM012562 PGS002214
(portability-ldpred2_neutrophil_perc)
 PSS008582|
Greater Middle Eastern Ancestry|
1,147 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.2984 [0.2443, 0.3507] sex, age, birth date, deprivation index, 16 PCs —
PPM012563 PGS002214
(portability-ldpred2_neutrophil_perc)
 PSS008360|
South Asian Ancestry|
6,055 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.2641 [0.2405, 0.2874] sex, age, birth date, deprivation index, 16 PCs —
PPM012564 PGS002214
(portability-ldpred2_neutrophil_perc)
 PSS008137|
East Asian Ancestry|
1,760 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.2471 [0.2025, 0.2907] sex, age, birth date, deprivation index, 16 PCs —
PPM012565 PGS002214
(portability-ldpred2_neutrophil_perc)
 PSS007924|
African Ancestry|
2,334 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.1602 [0.1202, 0.1996] sex, age, birth date, deprivation index, 16 PCs —
PPM012566 PGS002214
(portability-ldpred2_neutrophil_perc)
 PSS009028|
African Ancestry|
3,681 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Neutrophil percentage — — Partial Correlation (partial-r): 0.1568 [0.125, 0.1882] sex, age, birth date, deprivation index, 16 PCs —
PPM017473 PGS003545
(cont-decay-log_neutrophil)
 PSS010910|
European Ancestry|
19,374 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil count — — partial-R2: 0.1 sex, age, deprivation index, PC1-16 —
PPM017557 PGS003545
(cont-decay-log_neutrophil)
 PSS010826|
European Ancestry|
3,981 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil count — — partial-R2: 0.09 sex, age, deprivation index, PC1-16 —
PPM017641 PGS003545
(cont-decay-log_neutrophil)
 PSS010658|
European Ancestry|
6,260 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil count — — partial-R2: 0.1 sex, age, deprivation index, PC1-16 —
PPM017725 PGS003545
(cont-decay-log_neutrophil)
 PSS010574|
Greater Middle Eastern Ancestry|
1,119 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil count — — partial-R2: 0.09 sex, age, deprivation index, PC1-16 —
PPM017809 PGS003545
(cont-decay-log_neutrophil)
 PSS010238|
European Ancestry|
2,259 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil count — — partial-R2: 0.11 sex, age, deprivation index, PC1-16 —
PPM017893 PGS003545
(cont-decay-log_neutrophil)
 PSS010490|
South Asian Ancestry|
6,008 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil count — — partial-R2: 0.09 sex, age, deprivation index, PC1-16 —
PPM017977 PGS003545
(cont-decay-log_neutrophil)
 PSS010406|
East Asian Ancestry|
1,749 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil count — — partial-R2: 0.04 sex, age, deprivation index, PC1-16 —
PPM018061 PGS003545
(cont-decay-log_neutrophil)
 PSS010322|
African Ancestry|
2,323 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil count — — partial-R2: 0.03 sex, age, deprivation index, PC1-16 —
PPM018145 PGS003545
(cont-decay-log_neutrophil)
 PSS010742|
African Ancestry|
3,668 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil count — — partial-R2: 0.02 sex, age, deprivation index, PC1-16 —
PPM017494 PGS003566
(cont-decay-neutrophil_perc)
 PSS010933|
European Ancestry|
19,342 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil percentage — — partial-R2: 0.09 sex, age, deprivation index, PC1-16 —
PPM017662 PGS003566
(cont-decay-neutrophil_perc)
 PSS010681|
European Ancestry|
6,254 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil percentage — — partial-R2: 0.08 sex, age, deprivation index, PC1-16 —
PPM017746 PGS003566
(cont-decay-neutrophil_perc)
 PSS010597|
Greater Middle Eastern Ancestry|
1,117 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil percentage — — partial-R2: 0.09 sex, age, deprivation index, PC1-16 —
PPM017830 PGS003566
(cont-decay-neutrophil_perc)
 PSS010261|
European Ancestry|
2,256 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil percentage — — partial-R2: 0.09 sex, age, deprivation index, PC1-16 —
PPM017914 PGS003566
(cont-decay-neutrophil_perc)
 PSS010513|
South Asian Ancestry|
6,003 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil percentage — — partial-R2: 0.07 sex, age, deprivation index, PC1-16 —
PPM017998 PGS003566
(cont-decay-neutrophil_perc)
 PSS010429|
East Asian Ancestry|
1,748 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil percentage — — partial-R2: 0.06 sex, age, deprivation index, PC1-16 —
PPM018082 PGS003566
(cont-decay-neutrophil_perc)
 PSS010345|
African Ancestry|
2,321 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil percentage — — partial-R2: 0.02 sex, age, deprivation index, PC1-16 —
PPM018166 PGS003566
(cont-decay-neutrophil_perc)
 PSS010765|
African Ancestry|
3,652 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil percentage — — partial-R2: 0.02 sex, age, deprivation index, PC1-16 —
PPM017578 PGS003566
(cont-decay-neutrophil_perc)
 PSS010849|
European Ancestry|
3,977 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Neutrophil percentage — — partial-R2: 0.09 sex, age, deprivation index, PC1-16 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009028 — — 3,681 individuals — African unspecified Nigeria (West Africa) UKB —
PSS010910 — — 19,374 individuals,
46.0 % Male samples
 Mean = 56.9 years
Sd = 7.9 years		 European white British UKB —
PSS006976 — — 6,120 individuals — African unspecified — UKB —
PSS006977 — — 1,654 individuals — East Asian — UKB —
PSS006978 — — 24,129 individuals — European non-white British ancestry UKB —
PSS006979 — — 7,491 individuals — South Asian — UKB —
PSS006980 — — 65,520 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS008137 — — 1,760 individuals — East Asian China (East Asia) UKB —
PSS010658 — — 6,260 individuals,
45.0 % Male samples
 Mean = 54.5 years
Sd = 8.4 years		 European Italian UKB —
PSS010406 — — 1,749 individuals,
33.0 % Male samples
 Mean = 52.5 years
Sd = 7.8 years		 East Asian Chinese UKB —
PSS008786 — — 6,419 individuals — European Italy (South Europe) UKB —
PSS010933 — — 19,342 individuals,
46.0 % Male samples
 Mean = 56.9 years
Sd = 7.9 years		 European white British UKB —
PSS007902 — — 2,336 individuals — African American or Afro-Caribbean Carribean UKB —
PSS010681 — — 6,254 individuals,
45.0 % Male samples
 Mean = 54.5 years
Sd = 8.4 years		 European Italian UKB —
PSS007001 — — 6,120 individuals — African unspecified — UKB —
PSS007002 — — 1,654 individuals — East Asian — UKB —
PSS007003 — — 24,130 individuals — European non-white British ancestry UKB —
PSS007004 — — 7,491 individuals — South Asian — UKB —
PSS007005 — — 65,520 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS010429 — — 1,748 individuals,
33.0 % Male samples
 Mean = 52.5 years
Sd = 7.8 years		 East Asian Chinese UKB —
PSS008808 — — 6,413 individuals — European Italy (South Europe) UKB —
PSS000290 — — 2,314 individuals — European
(French Canadian)		 — CARTaGENE —
PSS000291 — — 39,260 individuals — European — INTERVAL —
PSS008560 — — 1,149 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS010826 — — 3,981 individuals,
38.0 % Male samples
 Mean = 54.3 years
Sd = 7.5 years		 European Polish UKB —
PSS009458 — — 19,382 individuals — European UK (+ Ireland) UKB —
PSS007924 — — 2,334 individuals — African American or Afro-Caribbean Carribean UKB —
PSS010574 — — 1,119 individuals,
60.0 % Male samples
 Mean = 52.0 years
Sd = 8.0 years		 Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB —
PSS010322 — — 2,323 individuals,
36.0 % Male samples
 Mean = 52.4 years
Sd = 8.0 years		 African American or Afro-Caribbean Caribbean UKB —
PSS008582 — — 1,147 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS010849 — — 3,977 individuals,
38.0 % Male samples
 Mean = 54.3 years
Sd = 7.5 years		 European Polish UKB —
PSS009480 — — 19,359 individuals — European UK (+ Ireland) UKB —
PSS010597 — — 1,117 individuals,
59.0 % Male samples
 Mean = 52.0 years
Sd = 8.0 years		 Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB —
PSS010345 — — 2,321 individuals,
36.0 % Male samples
 Mean = 52.4 years
Sd = 8.0 years		 African American or Afro-Caribbean Caribbean UKB —
PSS000144 — — 39,138 individuals,
50.0 % Male samples
 Mean = 43.84 years
Range = [18.0, 76.4] years		 European — INTERVAL —
PSS000145 — — 39,190 individuals,
50.0 % Male samples
 Mean = 43.83 years
Range = [18.0, 76.4] years		 European — INTERVAL —
PSS009232 — — 3,992 individuals — European Poland (NE Europe) UKB —
PSS008338 — — 6,060 individuals — South Asian India (South Asia) UKB —
PSS010742 — — 3,668 individuals,
47.0 % Male samples
 Mean = 51.9 years
Sd = 8.1 years		 African unspecified Nigerian UKB —
PSS010490 — — 6,008 individuals,
55.0 % Male samples
 Mean = 53.3 years
Sd = 8.4 years		 South Asian Indian UKB —
PSS010238 — — 2,259 individuals,
45.0 % Male samples
 Mean = 58.0 years
Sd = 7.1 years		 European Ashkenazi UKB —
PSS009254 — — 3,988 individuals — European Poland (NE Europe) UKB —
PSS008360 — — 6,055 individuals — South Asian India (South Asia) UKB —
PSS000170 — — 81,358 individuals,
45.0 % Male samples
 Mean = 57.19 years
Range = [40.19, 72.44] years		 European — UKB —
PSS000171 — — 81,423 individuals,
46.0 % Male samples
 Mean = 57.25 years
Range = [39.99, 70.5] years		 European — UKB —
PSS009006 — — 3,697 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008115 — — 1,761 individuals — East Asian China (East Asia) UKB —
PSS010765 — — 3,652 individuals,
47.0 % Male samples
 Mean = 51.9 years
Sd = 8.1 years		 African unspecified Nigerian UKB —
PSS010513 — — 6,003 individuals,
55.0 % Male samples
 Mean = 53.3 years
Sd = 8.4 years		 South Asian Indian UKB —
PSS010261 — — 2,256 individuals,
45.0 % Male samples
 Mean = 58.0 years
Sd = 7.1 years		 European Ashkenazi UKB —