Trait: smoking behaviour measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0005671
Description the quantification of some smoking or smoking-related behaviour, usually self-reported via a questionnaire
Trait category
Other measurement
Child trait(s) 3 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "smoking behaviour measurement" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS001046
(GBE_BIN_FC40001249)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Past tobacco smoking (Smoked at least once) tobacco smoke exposure measurement 6,169
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001046/ScoringFiles/PGS001046.txt.gz
PGS001047
(GBE_BIN_FC20001249)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Past tobacco smoking (Smoked occasionally) tobacco smoke exposure measurement 2,245
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001047/ScoringFiles/PGS001047.txt.gz
PGS001127
(GBE_BIN_FC10020116)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Never Smoker smoking status measurement 12,310
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001127/ScoringFiles/PGS001127.txt.gz
PGS001128
(GBE_BIN_FC20020116)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Previous Smoker smoking status measurement 4,348
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001128/ScoringFiles/PGS001128.txt.gz
PGS001129
(GBE_BIN_FC30022506)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Smoking status (ever vs never smokers) smoking status measurement 974
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001129/ScoringFiles/PGS001129.txt.gz
PGS001130
(GBE_INI2887)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Number of cigarettes previously smoked per day cigarettes per day measurement 725
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001130/ScoringFiles/PGS001130.txt.gz
PGS001139
(GBE_BIN_FC10002644)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Light smokers, at least 100 smokes in lifetime smoking behaviour measurement 11
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001139/ScoringFiles/PGS001139.txt.gz
PGS001388
(GBE_QT_FC10003476)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Difficulty not smoking for 1 day smoking behaviour measurement 1
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001388/ScoringFiles/PGS001388.txt.gz
PGS001515
(GBE_INI3456)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Number of cigarettes currently smoked daily (current cigarette smokers) cigarettes per day measurement 9
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001515/ScoringFiles/PGS001515.txt.gz
PGS001532
(GBE_QT_FC10003466)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Time from waking to first cigarette smoking behaviour measurement 86
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001532/ScoringFiles/PGS001532.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007988 PGS001046
(GBE_BIN_FC40001249)
PSS003919|
African Ancestry|
5,926 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Past tobacco smoking (Smoked at least once) AUROC: 0.66013 [0.64587, 0.67439] : 0.09483
Incremental AUROC (full-covars): -0.00813
PGS R2 (no covariates): 0.00042
PGS AUROC (no covariates): 0.48937 [0.47391, 0.50483]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007989 PGS001046
(GBE_BIN_FC40001249)
PSS003920|
East Asian Ancestry|
1,577 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Past tobacco smoking (Smoked at least once) AUROC: 0.67494 [0.64523, 0.70464] : 0.12932
Incremental AUROC (full-covars): 0.00219
PGS R2 (no covariates): 0.00369
PGS AUROC (no covariates): 0.53021 [0.49937, 0.56105]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007990 PGS001046
(GBE_BIN_FC40001249)
PSS003921|
European Ancestry|
22,450 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Past tobacco smoking (Smoked at least once) AUROC: 0.59705 [0.58934, 0.60476] : 0.03706
Incremental AUROC (full-covars): 0.01391
PGS R2 (no covariates): 0.00997
PGS AUROC (no covariates): 0.55171 [0.54388, 0.55954]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007991 PGS001046
(GBE_BIN_FC40001249)
PSS003922|
South Asian Ancestry|
7,192 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Past tobacco smoking (Smoked at least once) AUROC: 0.74129 [0.72884, 0.75373] : 0.20316
Incremental AUROC (full-covars): 0.00744
PGS R2 (no covariates): 0.00794
PGS AUROC (no covariates): 0.54619 [0.53131, 0.56108]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007992 PGS001046
(GBE_BIN_FC40001249)
PSS003923|
European Ancestry|
62,410 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Past tobacco smoking (Smoked at least once) AUROC: 0.61588 [0.61146, 0.6203] : 0.05447
Incremental AUROC (full-covars): 0.01564
PGS R2 (no covariates): 0.01446
PGS AUROC (no covariates): 0.55938 [0.55485, 0.56391]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007993 PGS001047
(GBE_BIN_FC20001249)
PSS003805|
African Ancestry|
5,926 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Past tobacco smoking (Smoked occasionally) AUROC: 0.58093 [0.55858, 0.60327] : 0.01829
Incremental AUROC (full-covars): -0.05921
PGS R2 (no covariates): 0.00064
PGS AUROC (no covariates): 0.49651 [0.47342, 0.51961]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007994 PGS001047
(GBE_BIN_FC20001249)
PSS003806|
East Asian Ancestry|
1,577 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Past tobacco smoking (Smoked occasionally) AUROC: 0.68329 [0.63933, 0.72724] : 0.07701
Incremental AUROC (full-covars): 0.00274
PGS R2 (no covariates): 0.00038
PGS AUROC (no covariates): 0.50548 [0.45563, 0.55533]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007995 PGS001047
(GBE_BIN_FC20001249)
PSS003807|
European Ancestry|
22,450 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Past tobacco smoking (Smoked occasionally) AUROC: 0.58823 [0.5791, 0.59736] : 0.0603
Incremental AUROC (full-covars): 0.00694
PGS R2 (no covariates): 0.00257
PGS AUROC (no covariates): 0.52958 [0.5197, 0.53945]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007996 PGS001047
(GBE_BIN_FC20001249)
PSS003808|
South Asian Ancestry|
7,192 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Past tobacco smoking (Smoked occasionally) AUROC: 0.70233 [0.68241, 0.72224] : 0.09047
Incremental AUROC (full-covars): 0.00461
PGS R2 (no covariates): 0.00302
PGS AUROC (no covariates): 0.53831 [0.51304, 0.56357]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007997 PGS001047
(GBE_BIN_FC20001249)
PSS003809|
European Ancestry|
62,410 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Past tobacco smoking (Smoked occasionally) AUROC: 0.59787 [0.59205, 0.6037] : 0.06
Incremental AUROC (full-covars): 0.01786
PGS R2 (no covariates): 0.00491
PGS AUROC (no covariates): 0.54138 [0.53499, 0.54777]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008363 PGS001127
(GBE_BIN_FC10020116)
PSS003750|
African Ancestry|
6,390 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Never Smoker AUROC: 0.65929 [0.64485, 0.67373] : 0.08669
Incremental AUROC (full-covars): -0.00756
PGS R2 (no covariates): 0.00049
PGS AUROC (no covariates): 0.51037 [0.49458, 0.52616]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008364 PGS001127
(GBE_BIN_FC10020116)
PSS003751|
East Asian Ancestry|
1,661 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Never Smoker AUROC: 0.71794 [0.68736, 0.74851] : 0.15281
Incremental AUROC (full-covars): 0.00859
PGS R2 (no covariates): 0.00367
PGS AUROC (no covariates): 0.53548 [0.50244, 0.56852]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008365 PGS001127
(GBE_BIN_FC10020116)
PSS003752|
European Ancestry|
24,816 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Never Smoker AUROC: 0.60529 [0.5983, 0.61228] : 0.04529
Incremental AUROC (full-covars): 0.0311
PGS R2 (no covariates): 0.02383
PGS AUROC (no covariates): 0.57608 [0.56899, 0.58317]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008366 PGS001127
(GBE_BIN_FC10020116)
PSS003753|
South Asian Ancestry|
7,615 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Never Smoker AUROC: 0.7532 [0.74067, 0.76574] : 0.20415
Incremental AUROC (full-covars): 0.01888
PGS R2 (no covariates): 0.01842
PGS AUROC (no covariates): 0.5755 [0.55967, 0.59134]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008367 PGS001127
(GBE_BIN_FC10020116)
PSS003754|
European Ancestry|
67,212 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Never Smoker AUROC: 0.62158 [0.61735, 0.62581] : 0.06047
Incremental AUROC (full-covars): 0.03481
PGS R2 (no covariates): 0.03106
PGS AUROC (no covariates): 0.58693 [0.58262, 0.59123]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008368 PGS001128
(GBE_BIN_FC20020116)
PSS003844|
African Ancestry|
6,390 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Previous Smoker AUROC: 0.62818 [0.61021, 0.64615] : 0.04625
Incremental AUROC (full-covars): -0.00333
PGS R2 (no covariates): 2e-05
PGS AUROC (no covariates): 0.49819 [0.47898, 0.5174]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008369 PGS001128
(GBE_BIN_FC20020116)
PSS003845|
East Asian Ancestry|
1,661 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Previous Smoker AUROC: 0.70433 [0.66805, 0.74061] PGS R2 (no covariates): 0.00293
: 0.11247
Incremental AUROC (full-covars): -0.00189
PGS AUROC (no covariates): 0.5352 [0.49491, 0.57548]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008370 PGS001128
(GBE_BIN_FC20020116)
PSS003846|
European Ancestry|
24,816 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Previous Smoker AUROC: 0.59213 [0.58495, 0.59931] : 0.03309
Incremental AUROC (full-covars): 0.00528
PGS R2 (no covariates): 0.0046
PGS AUROC (no covariates): 0.53522 [0.5279, 0.54253]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008371 PGS001128
(GBE_BIN_FC20020116)
PSS003847|
South Asian Ancestry|
7,615 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Previous Smoker AUROC: 0.73887 [0.72262, 0.75511] : 0.14448
Incremental AUROC (full-covars): 0.00362
PGS R2 (no covariates): 0.00301
PGS AUROC (no covariates): 0.53352 [0.51394, 0.55311]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008372 PGS001128
(GBE_BIN_FC20020116)
PSS003848|
European Ancestry|
67,212 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Previous Smoker AUROC: 0.61185 [0.60741, 0.61629] : 0.04715
Incremental AUROC (full-covars): 0.01019
PGS R2 (no covariates): 0.0091
PGS AUROC (no covariates): 0.5477 [0.54318, 0.55223]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008373 PGS001129
(GBE_BIN_FC30022506)
PSS003904|
African Ancestry|
511 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Tobacco smoking ever vs no AUROC: 0.6456 [0.59467, 0.69652] : 0.08383
Incremental AUROC (full-covars): -0.01967
PGS R2 (no covariates): 0.01985
PGS AUROC (no covariates): 0.42965 [0.37629, 0.483]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008374 PGS001129
(GBE_BIN_FC30022506)
PSS003905|
East Asian Ancestry|
243 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Tobacco smoking ever vs no AUROC: 0.72543 [0.64779, 0.80307] : 0.18478
Incremental AUROC (full-covars): 0.00769
PGS R2 (no covariates): 0.02947
PGS AUROC (no covariates): 0.59444 [0.50179, 0.6871]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008375 PGS001129
(GBE_BIN_FC30022506)
PSS003906|
European Ancestry|
5,929 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Tobacco smoking ever vs no AUROC: 0.59066 [0.5762, 0.60512] : 0.03312
Incremental AUROC (full-covars): 0.00637
PGS R2 (no covariates): 0.00344
PGS AUROC (no covariates): 0.52696 [0.51226, 0.54167]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008376 PGS001129
(GBE_BIN_FC30022506)
PSS003907|
South Asian Ancestry|
699 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Tobacco smoking ever vs no AUROC: 0.69293 [0.64829, 0.73757] : 0.12848
Incremental AUROC (full-covars): 0.00403
PGS R2 (no covariates): 0.00894
PGS AUROC (no covariates): 0.55217 [0.50411, 0.60023]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008377 PGS001129
(GBE_BIN_FC30022506)
PSS003908|
European Ancestry|
17,150 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Tobacco smoking ever vs no AUROC: 0.59861 [0.58997, 0.60724] : 0.03796
Incremental AUROC (full-covars): 0.00411
PGS R2 (no covariates): 0.00371
PGS AUROC (no covariates): 0.52942 [0.52057, 0.53826]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008378 PGS001130
(GBE_INI2887)
PSS006871|
African Ancestry|
553 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: # of cigarettes previously smoked daily : 0.05257 [0.04201, 0.06313]
Incremental R2 (full-covars): -0.00029
PGS R2 (no covariates): 0.00089 [-0.00056, 0.00234]
age, sex, UKB array type, Genotype PCs
PPM008379 PGS001130
(GBE_INI2887)
PSS006872|
East Asian Ancestry|
122 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: # of cigarettes previously smoked daily : 0.20745 [0.17324, 0.24166]
Incremental R2 (full-covars): -0.00582
PGS R2 (no covariates): 0.00074 [-0.00184, 0.00332]
age, sex, UKB array type, Genotype PCs
PPM008380 PGS001130
(GBE_INI2887)
PSS006873|
European Ancestry|
6,735 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: # of cigarettes previously smoked daily : 0.10992 [0.10259, 0.11725]
Incremental R2 (full-covars): 0.00885
PGS R2 (no covariates): 0.00973 [0.0073, 0.01215]
age, sex, UKB array type, Genotype PCs
PPM008381 PGS001130
(GBE_INI2887)
PSS006874|
South Asian Ancestry|
585 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: # of cigarettes previously smoked daily : 0.0678 [0.05705, 0.07855]
Incremental R2 (full-covars): -0.00447
PGS R2 (no covariates): 0.00066 [-0.00048, 0.0018]
age, sex, UKB array type, Genotype PCs
PPM008382 PGS001130
(GBE_INI2887)
PSS006875|
European Ancestry|
15,927 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: # of cigarettes previously smoked daily : 0.0979 [0.09364, 0.10216]
Incremental R2 (full-covars): 0.0054
PGS R2 (no covariates): 0.00613 [0.00496, 0.00731]
age, sex, UKB array type, Genotype PCs
PPM008422 PGS001139
(GBE_BIN_FC10002644)
PSS003726|
African Ancestry|
1,411 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Light smokers, at least 100 smokes in lifetime AUROC: 0.60475 [0.57362, 0.63587] : 0.04431
Incremental AUROC (full-covars): -0.00017
PGS R2 (no covariates): 0.00387
PGS AUROC (no covariates): 0.52025 [0.48862, 0.55188]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008423 PGS001139
(GBE_BIN_FC10002644)
PSS003727|
East Asian Ancestry|
340 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Light smokers, at least 100 smokes in lifetime AUROC: 0.72018 [0.66282, 0.77753] : 0.18473
Incremental AUROC (full-covars): 0.00217
PGS R2 (no covariates): 0.0059
PGS AUROC (no covariates): 0.50127 [0.43399, 0.56856]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008424 PGS001139
(GBE_BIN_FC10002644)
PSS003728|
European Ancestry|
7,260 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Light smokers, at least 100 smokes in lifetime AUROC: 0.5677 [0.55413, 0.58127] : 0.01989
Incremental AUROC (full-covars): 0.00081
PGS R2 (no covariates): 0.00134
PGS AUROC (no covariates): 0.51767 [0.50394, 0.5314]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008425 PGS001139
(GBE_BIN_FC10002644)
PSS003729|
South Asian Ancestry|
1,269 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Light smokers, at least 100 smokes in lifetime AUROC: 0.63663 [0.60494, 0.66832] : 0.07807
Incremental AUROC (full-covars): 0.00531
PGS R2 (no covariates): 0.00278
PGS AUROC (no covariates): 0.5327 [0.49921, 0.56619]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008426 PGS001139
(GBE_BIN_FC10002644)
PSS003730|
European Ancestry|
18,557 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Light smokers, at least 100 smokes in lifetime AUROC: 0.57908 [0.57055, 0.58761] : 0.02444
Incremental AUROC (full-covars): 0.00325
PGS R2 (no covariates): 0.00154
PGS AUROC (no covariates): 0.52034 [0.51172, 0.52897]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007240 PGS001388
(GBE_QT_FC10003476)
PSS007516|
African Ancestry|
442 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Difficulty not smoking for 1 day : 0.02875 [0.02075, 0.03676]
Incremental R2 (full-covars): -0.00116
PGS R2 (no covariates): 0.00583 [0.00214, 0.00952]
age, sex, UKB array type, Genotype PCs
PPM007241 PGS001388
(GBE_QT_FC10003476)
PSS007517|
East Asian Ancestry|
83 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Difficulty not smoking for 1 day : 0.10272 [0.07547, 0.12998]
Incremental R2 (full-covars): 0.00128
PGS R2 (no covariates): 0.00197 [-0.00223, 0.00617]
age, sex, UKB array type, Genotype PCs
PPM007242 PGS001388
(GBE_QT_FC10003476)
PSS007518|
European Ancestry|
2,332 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Difficulty not smoking for 1 day : 0.03812 [0.03345, 0.04278]
Incremental R2 (full-covars): 0.00242
PGS R2 (no covariates): 0.00399 [0.00242, 0.00555]
age, sex, UKB array type, Genotype PCs
PPM007243 PGS001388
(GBE_QT_FC10003476)
PSS007519|
South Asian Ancestry|
411 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Difficulty not smoking for 1 day : 0.0459 [0.03685, 0.05495]
Incremental R2 (full-covars): 0.00319
PGS R2 (no covariates): 0.00748 [0.00368, 0.01128]
age, sex, UKB array type, Genotype PCs
PPM007244 PGS001388
(GBE_QT_FC10003476)
PSS007520|
European Ancestry|
4,595 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Difficulty not smoking for 1 day : 0.02069 [0.01856, 0.02281]
Incremental R2 (full-covars): 0.00258
PGS R2 (no covariates): 0.00561 [0.00449, 0.00674]
age, sex, UKB array type, Genotype PCs
PPM007085 PGS001515
(GBE_INI3456)
PSS007246|
African Ancestry|
438 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: # of cigarettes currently smoked daily (current cigarette smokers) : 0.01822 [0.01178, 0.02466]
Incremental R2 (full-covars): -0.00395
PGS R2 (no covariates): 0.00404 [0.00097, 0.00712]
age, sex, UKB array type, Genotype PCs
PPM007086 PGS001515
(GBE_INI3456)
PSS007247|
East Asian Ancestry|
86 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: # of cigarettes currently smoked daily (current cigarette smokers) : 0.1229 [0.09376, 0.15204]
Incremental R2 (full-covars): 0.00955
PGS R2 (no covariates): 0.02937 [0.01361, 0.04513]
age, sex, UKB array type, Genotype PCs
PPM007087 PGS001515
(GBE_INI3456)
PSS007248|
European Ancestry|
2,329 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: # of cigarettes currently smoked daily (current cigarette smokers) : 0.09619 [0.08923, 0.10315]
Incremental R2 (full-covars): 0.00371
PGS R2 (no covariates): 0.00361 [0.00212, 0.0051]
age, sex, UKB array type, Genotype PCs
PPM007088 PGS001515
(GBE_INI3456)
PSS007249|
South Asian Ancestry|
411 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: # of cigarettes currently smoked daily (current cigarette smokers) : 0.04868 [0.03939, 0.05797]
Incremental R2 (full-covars): 0.01303
PGS R2 (no covariates): 0.01795 [0.01212, 0.02377]
age, sex, UKB array type, Genotype PCs
PPM007089 PGS001515
(GBE_INI3456)
PSS007250|
European Ancestry|
4,562 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: # of cigarettes currently smoked daily (current cigarette smokers) : 0.07868 [0.07478, 0.08258]
Incremental R2 (full-covars): 0.00371
PGS R2 (no covariates): 0.00532 [0.00423, 0.00642]
age, sex, UKB array type, Genotype PCs
PPM007235 PGS001532
(GBE_QT_FC10003466)
PSS007511|
African Ancestry|
436 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Time from waking to first cigarette : 0.02268 [0.01552, 0.02983]
Incremental R2 (full-covars): -0.00073
PGS R2 (no covariates): 3e-05 [-0.00022, 0.00028]
age, sex, UKB array type, Genotype PCs
PPM007236 PGS001532
(GBE_QT_FC10003466)
PSS007512|
East Asian Ancestry|
81 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Time from waking to first cigarette : 0.08524 [0.05993, 0.11055]
Incremental R2 (full-covars): -0.00086
PGS R2 (no covariates): 8e-05 [-0.00076, 0.00091]
age, sex, UKB array type, Genotype PCs
PPM007237 PGS001532
(GBE_QT_FC10003466)
PSS007513|
European Ancestry|
2,322 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Time from waking to first cigarette : 0.06234 [0.05652, 0.06815]
Incremental R2 (full-covars): 0.00303
PGS R2 (no covariates): 0.004 [0.00244, 0.00557]
age, sex, UKB array type, Genotype PCs
PPM007238 PGS001532
(GBE_QT_FC10003466)
PSS007514|
South Asian Ancestry|
400 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Time from waking to first cigarette : 0.05309 [0.04343, 0.06275]
Incremental R2 (full-covars): 0.00544
PGS R2 (no covariates): 0.0094 [0.00514, 0.01365]
age, sex, UKB array type, Genotype PCs
PPM007239 PGS001532
(GBE_QT_FC10003466)
PSS007515|
European Ancestry|
4,577 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Time from waking to first cigarette : 0.03007 [0.02753, 0.03261]
Incremental R2 (full-covars): 0.0036
PGS R2 (no covariates): 0.00595 [0.00479, 0.00711]
age, sex, UKB array type, Genotype PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS003904
[
  • 150 cases
  • , 361 controls
]
African unspecified UKB
PSS003905
[
  • 48 cases
  • , 195 controls
]
East Asian UKB
PSS003906
[
  • 2,751 cases
  • , 3,178 controls
]
European non-white British ancestry UKB
PSS003907
[
  • 169 cases
  • , 530 controls
]
South Asian UKB
PSS003908
[
  • 6,855 cases
  • , 10,295 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS007513 2,322 individuals European non-white British ancestry UKB
PSS007511 436 individuals African unspecified UKB
PSS007246 438 individuals African unspecified UKB
PSS003919
[
  • 2,092 cases
  • , 3,834 controls
]
African unspecified UKB
PSS003920
[
  • 495 cases
  • , 1,082 controls
]
East Asian UKB
PSS003921
[
  • 14,474 cases
  • , 7,976 controls
]
European non-white British ancestry UKB
PSS003922
[
  • 1,964 cases
  • , 5,228 controls
]
South Asian UKB
PSS003923
[
  • 35,715 cases
  • , 26,695 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS007247 86 individuals East Asian UKB
PSS007248 2,329 individuals European non-white British ancestry UKB
PSS007249 411 individuals South Asian UKB
PSS006871 553 individuals African unspecified UKB
PSS006872 122 individuals East Asian UKB
PSS006873 6,735 individuals European non-white British ancestry UKB
PSS006874 585 individuals South Asian UKB
PSS006875 15,927 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS007516 442 individuals African unspecified UKB
PSS003805
[
  • 743 cases
  • , 5,183 controls
]
African unspecified UKB
PSS003806
[
  • 152 cases
  • , 1,425 controls
]
East Asian UKB
PSS003807
[
  • 4,013 cases
  • , 18,437 controls
]
European non-white British ancestry UKB
PSS003808
[
  • 570 cases
  • , 6,622 controls
]
South Asian UKB
PSS003809
[
  • 9,036 cases
  • , 53,374 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS007517 83 individuals East Asian UKB
PSS007518 2,332 individuals European non-white British ancestry UKB
PSS007519 411 individuals South Asian UKB
PSS007520 4,595 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS007514 400 individuals South Asian UKB
PSS007515 4,577 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS003844
[
  • 1,071 cases
  • , 5,319 controls
]
African unspecified UKB
PSS003845
[
  • 237 cases
  • , 1,424 controls
]
East Asian UKB
PSS003846
[
  • 9,959 cases
  • , 14,857 controls
]
European non-white British ancestry UKB
PSS003847
[
  • 962 cases
  • , 6,653 controls
]
South Asian UKB
PSS003848
[
  • 23,931 cases
  • , 43,281 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS003726
[
  • 599 cases
  • , 812 controls
]
African unspecified UKB
PSS003727
[
  • 124 cases
  • , 216 controls
]
East Asian UKB
PSS003728
[
  • 3,751 cases
  • , 3,509 controls
]
European non-white British ancestry UKB
PSS003729
[
  • 567 cases
  • , 702 controls
]
South Asian UKB
PSS003730
[
  • 8,496 cases
  • , 10,061 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS003750
[
  • 4,607 cases
  • , 1,783 controls
]
African unspecified UKB
PSS003751
[
  • 1,302 cases
  • , 359 controls
]
East Asian UKB
PSS003752
[
  • 11,638 cases
  • , 13,178 controls
]
European non-white British ancestry UKB
PSS003753
[
  • 6,019 cases
  • , 1,596 controls
]
South Asian UKB
PSS003754
[
  • 37,219 cases
  • , 29,993 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS007250 4,562 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS007512 81 individuals East Asian UKB