Trait: grip strength measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0006941
Description quantification of the force applied by the hand to pull on or suspend from objects
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001119
(GBE_INI46)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Left hand grip strength grip strength measurement 13,767
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001119/ScoringFiles/PGS001119.txt.gz
PGS001120
(GBE_INI47)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Right hand grip strength grip strength measurement 12,644
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001120/ScoringFiles/PGS001120.txt.gz
PGS001927
(portability-PLR_hand_grip_strength)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hand grip strength (mean of both) grip strength measurement 73,846
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001927/ScoringFiles/PGS001927.txt.gz
PGS002143
(portability-ldpred2_hand_grip_strength)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hand grip strength (mean of both) grip strength measurement 966,283
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002143/ScoringFiles/PGS002143.txt.gz
PGS003513
(cont-decay-hand_grip_strength)
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Hand grip strength (mean of both) grip strength measurement 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003513/ScoringFiles/PGS003513.txt.gz
PGS004428
(X46.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Hand grip strength (left) grip strength measurement 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004428/ScoringFiles/PGS004428.txt.gz
PGS004429
(X47.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Hand grip strength (right) grip strength measurement 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004429/ScoringFiles/PGS004429.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM008333 PGS001119
(GBE_INI46)
 PSS007346|
African Ancestry|
6,406 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hand grip strength (L) — — R²: 0.46137 [0.44358, 0.47915]
Incremental R2 (full-covars): -0.00082
PGS R2 (no covariates): 0.00155 [-0.00036, 0.00346]		 age, sex, UKB array type, Genotype PCs —
PPM008334 PGS001119
(GBE_INI46)
 PSS007347|
East Asian Ancestry|
1,696 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hand grip strength (L) — — R²: 0.51785 [0.48497, 0.55073]
Incremental R2 (full-covars): 0.00522
PGS R2 (no covariates): 0.01076 [0.00104, 0.02048]		 age, sex, UKB array type, Genotype PCs —
PPM008335 PGS001119
(GBE_INI46)
 PSS007348|
European Ancestry|
24,787 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hand grip strength (L) — — R²: 0.54413 [0.53578, 0.55248]
Incremental R2 (full-covars): 0.01167
PGS R2 (no covariates): 0.01075 [0.0082, 0.01329]		 age, sex, UKB array type, Genotype PCs —
PPM008336 PGS001119
(GBE_INI46)
 PSS007349|
South Asian Ancestry|
7,727 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hand grip strength (L) — — R²: 0.48797 [0.47214, 0.50381]
Incremental R2 (full-covars): 0.00538
PGS R2 (no covariates): 0.00871 [0.00462, 0.01281]		 age, sex, UKB array type, Genotype PCs —
PPM008337 PGS001119
(GBE_INI46)
 PSS007350|
European Ancestry|
67,154 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hand grip strength (L) — — R²: 0.57766 [0.57281, 0.5825]
Incremental R2 (full-covars): 0.01506
PGS R2 (no covariates): 0.01441 [0.01262, 0.0162]		 age, sex, UKB array type, Genotype PCs —
PPM008338 PGS001120
(GBE_INI47)
 PSS007351|
African Ancestry|
6,401 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hand grip strength (R) — — R²: 0.46894 [0.45127, 0.48662]
Incremental R2 (full-covars): 0.00206
PGS R2 (no covariates): 0.00239 [0.00002, 0.00476]		 age, sex, UKB array type, Genotype PCs —
PPM008339 PGS001120
(GBE_INI47)
 PSS007352|
East Asian Ancestry|
1,696 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hand grip strength (R) — — R²: 0.52807 [0.49557, 0.56056]
Incremental R2 (full-covars): 0.00381
PGS R2 (no covariates): 0.00613 [-0.00124, 0.01351]		 age, sex, UKB array type, Genotype PCs —
PPM008340 PGS001120
(GBE_INI47)
 PSS007353|
European Ancestry|
24,789 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hand grip strength (R) — — R²: 0.55224 [0.54398, 0.5605]
Incremental R2 (full-covars): 0.01267
PGS R2 (no covariates): 0.01229 [0.00957, 0.01501]		 age, sex, UKB array type, Genotype PCs —
PPM008341 PGS001120
(GBE_INI47)
 PSS007354|
South Asian Ancestry|
7,741 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hand grip strength (R) — — R²: 0.48203 [0.46611, 0.49796]
Incremental R2 (full-covars): 0.00822
PGS R2 (no covariates): 0.00897 [0.00481, 0.01312]		 age, sex, UKB array type, Genotype PCs —
PPM008342 PGS001120
(GBE_INI47)
 PSS007355|
European Ancestry|
67,185 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hand grip strength (R) — — R²: 0.57637 [0.57152, 0.58123]
Incremental R2 (full-covars): 0.01651
PGS R2 (no covariates): 0.01531 [0.01347, 0.01715]		 age, sex, UKB array type, Genotype PCs —
PPM010291 PGS001927
(portability-PLR_hand_grip_strength)
 PSS009413|
European Ancestry|
19,855 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.2515 [0.2384, 0.2645] sex, age, birth date, deprivation index, 16 PCs —
PPM010292 PGS001927
(portability-PLR_hand_grip_strength)
 PSS009187|
European Ancestry|
4,105 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.2485 [0.2195, 0.2771] sex, age, birth date, deprivation index, 16 PCs —
PPM010293 PGS001927
(portability-PLR_hand_grip_strength)
 PSS008741|
European Ancestry|
6,598 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.2292 [0.2062, 0.252] sex, age, birth date, deprivation index, 16 PCs —
PPM010294 PGS001927
(portability-PLR_hand_grip_strength)
 PSS008515|
Greater Middle Eastern Ancestry|
1,168 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.1973 [0.1411, 0.2523] sex, age, birth date, deprivation index, 16 PCs —
PPM010296 PGS001927
(portability-PLR_hand_grip_strength)
 PSS008070|
East Asian Ancestry|
1,799 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.1616 [0.116, 0.2065] sex, age, birth date, deprivation index, 16 PCs —
PPM010297 PGS001927
(portability-PLR_hand_grip_strength)
 PSS007857|
African Ancestry|
2,448 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.0843 [0.0446, 0.1236] sex, age, birth date, deprivation index, 16 PCs —
PPM010298 PGS001927
(portability-PLR_hand_grip_strength)
 PSS008961|
African Ancestry|
3,849 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.0651 [0.0334, 0.0965] sex, age, birth date, deprivation index, 16 PCs —
PPM010295 PGS001927
(portability-PLR_hand_grip_strength)
 PSS008293|
South Asian Ancestry|
6,223 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.1688 [0.1445, 0.1929] sex, age, birth date, deprivation index, 16 PCs —
PPM011995 PGS002143
(portability-ldpred2_hand_grip_strength)
 PSS008293|
South Asian Ancestry|
6,223 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.1759 [0.1517, 0.1999] sex, age, birth date, deprivation index, 16 PCs —
PPM011991 PGS002143
(portability-ldpred2_hand_grip_strength)
 PSS009413|
European Ancestry|
19,855 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.262 [0.249, 0.2749] sex, age, birth date, deprivation index, 16 PCs —
PPM011992 PGS002143
(portability-ldpred2_hand_grip_strength)
 PSS009187|
European Ancestry|
4,105 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.2543 [0.2254, 0.2827] sex, age, birth date, deprivation index, 16 PCs —
PPM011993 PGS002143
(portability-ldpred2_hand_grip_strength)
 PSS008741|
European Ancestry|
6,598 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.2433 [0.2204, 0.2659] sex, age, birth date, deprivation index, 16 PCs —
PPM011994 PGS002143
(portability-ldpred2_hand_grip_strength)
 PSS008515|
Greater Middle Eastern Ancestry|
1,168 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.2026 [0.1465, 0.2575] sex, age, birth date, deprivation index, 16 PCs —
PPM011996 PGS002143
(portability-ldpred2_hand_grip_strength)
 PSS008070|
East Asian Ancestry|
1,799 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.1631 [0.1175, 0.208] sex, age, birth date, deprivation index, 16 PCs —
PPM011997 PGS002143
(portability-ldpred2_hand_grip_strength)
 PSS007857|
African Ancestry|
2,448 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.0966 [0.0571, 0.1359] sex, age, birth date, deprivation index, 16 PCs —
PPM011998 PGS002143
(portability-ldpred2_hand_grip_strength)
 PSS008961|
African Ancestry|
3,849 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hand grip strength (mean of both) — — Partial Correlation (partial-r): 0.0798 [0.0482, 0.1112] sex, age, birth date, deprivation index, 16 PCs —
PPM017441 PGS003513
(cont-decay-hand_grip_strength)
 PSS010875|
European Ancestry|
19,862 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hand grip strength (mean of both) — — partial-R2: 0.06 sex, age, deprivation index, PC1-16 —
PPM017525 PGS003513
(cont-decay-hand_grip_strength)
 PSS010791|
European Ancestry|
4,094 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hand grip strength (mean of both) — — partial-R2: 0.06 sex, age, deprivation index, PC1-16 —
PPM017609 PGS003513
(cont-decay-hand_grip_strength)
 PSS010623|
European Ancestry|
6,434 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hand grip strength (mean of both) — — partial-R2: 0.06 sex, age, deprivation index, PC1-16 —
PPM017693 PGS003513
(cont-decay-hand_grip_strength)
 PSS010539|
Greater Middle Eastern Ancestry|
1,139 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hand grip strength (mean of both) — — partial-R2: 0.04 sex, age, deprivation index, PC1-16 —
PPM017777 PGS003513
(cont-decay-hand_grip_strength)
 PSS010203|
European Ancestry|
2,336 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hand grip strength (mean of both) — — partial-R2: 0.05 sex, age, deprivation index, PC1-16 —
PPM017861 PGS003513
(cont-decay-hand_grip_strength)
 PSS010455|
South Asian Ancestry|
6,171 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hand grip strength (mean of both) — — partial-R2: 0.03 sex, age, deprivation index, PC1-16 —
PPM017945 PGS003513
(cont-decay-hand_grip_strength)
 PSS010371|
East Asian Ancestry|
1,787 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hand grip strength (mean of both) — — partial-R2: 0.02 sex, age, deprivation index, PC1-16 —
PPM018029 PGS003513
(cont-decay-hand_grip_strength)
 PSS010287|
African Ancestry|
2,435 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hand grip strength (mean of both) — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM018113 PGS003513
(cont-decay-hand_grip_strength)
 PSS010707|
African Ancestry|
3,819 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hand grip strength (mean of both) — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM020543 PGS004428
(X46.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Hand grip strength (left) — — PGS R2 (no covariates): 0.12037 — —
PPM020544 PGS004429
(X47.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Hand grip strength (right) — — PGS R2 (no covariates): 0.11968 — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009413 — — 19,855 individuals — European UK (+ Ireland) UKB —
PSS007355 — — 67,185 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS010791 — — 4,094 individuals,
38.0 % Male samples
 Mean = 54.3 years
Sd = 7.5 years		 European Polish UKB —
PSS010539 — — 1,139 individuals,
60.0 % Male samples
 Mean = 52.0 years
Sd = 8.0 years		 Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB —
PSS010287 — — 2,435 individuals,
36.0 % Male samples
 Mean = 52.5 years
Sd = 8.1 years		 African American or Afro-Caribbean Caribbean UKB —
PSS009187 — — 4,105 individuals — European Poland (NE Europe) UKB —
PSS008293 — — 6,223 individuals — South Asian India (South Asia) UKB —
PSS010707 — — 3,819 individuals,
46.0 % Male samples
 Mean = 51.9 years
Sd = 8.1 years		 African unspecified Nigerian UKB —
PSS010455 — — 6,171 individuals,
54.0 % Male samples
 Mean = 53.3 years
Sd = 8.4 years		 South Asian Indian UKB —
PSS008961 — — 3,849 individuals — African unspecified Nigeria (West Africa) UKB —
PSS010203 — — 2,336 individuals,
45.0 % Male samples
 Mean = 58.1 years
Sd = 7.1 years		 European Ashkenazi UKB —
PSS008070 — — 1,799 individuals — East Asian China (East Asia) UKB —
PSS011364 — — 56,192 individuals — European — UKB —
PSS010875 — — 19,862 individuals,
46.0 % Male samples
 Mean = 56.9 years
Sd = 7.9 years		 European white British UKB —
PSS008741 — — 6,598 individuals — European Italy (South Europe) UKB —
PSS010623 — — 6,434 individuals,
45.0 % Male samples
 Mean = 54.5 years
Sd = 8.4 years		 European Italian UKB —
PSS010371 — — 1,787 individuals,
33.0 % Male samples
 Mean = 52.4 years
Sd = 7.8 years		 East Asian Chinese UKB —
PSS007857 — — 2,448 individuals — African American or Afro-Caribbean Carribean UKB —
PSS007346 — — 6,406 individuals — African unspecified — UKB —
PSS007347 — — 1,696 individuals — East Asian — UKB —
PSS007348 — — 24,787 individuals — European non-white British ancestry UKB —
PSS007349 — — 7,727 individuals — South Asian — UKB —
PSS007350 — — 67,154 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS007351 — — 6,401 individuals — African unspecified — UKB —
PSS007352 — — 1,696 individuals — East Asian — UKB —
PSS007353 — — 24,789 individuals — European non-white British ancestry UKB —
PSS007354 — — 7,741 individuals — South Asian — UKB —
PSS008515 — — 1,168 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —