Trait: health trait

Experimental Factor Ontology (EFO) Information
Identifier EFO_0007652
Description The characteristics in health that a certain person has.
Trait category
Other trait

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002000
(portability-PLR_poorer_health)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Overall health rating health trait 53,716
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002000/ScoringFiles/PGS002000.txt.gz
PGS002004
(portability-PLR_sensitive_stomach)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Sensitive stomach health trait 3,970
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002004/ScoringFiles/PGS002004.txt.gz
PGS002218
(portability-ldpred2_poorer_health)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Overall health rating health trait 958,362
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002218/ScoringFiles/PGS002218.txt.gz
PGS002223
(portability-ldpred2_sensitive_stomach)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Sensitive stomach health trait 795,614
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002223/ScoringFiles/PGS002223.txt.gz
PGS003568
(cont-decay-sensitive_stomach)
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Sensitive stomach health trait 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003568/ScoringFiles/PGS003568.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010875 PGS002000
(portability-PLR_poorer_health)
 PSS009484|
European Ancestry|
19,916 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.1677 [0.1542, 0.1812] sex, age, birth date, deprivation index, 16 PCs —
PPM010876 PGS002000
(portability-PLR_poorer_health)
 PSS009258|
European Ancestry|
4,073 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.1454 [0.1151, 0.1754] sex, age, birth date, deprivation index, 16 PCs —
PPM010877 PGS002000
(portability-PLR_poorer_health)
 PSS008812|
European Ancestry|
6,579 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.1449 [0.1212, 0.1686] sex, age, birth date, deprivation index, 16 PCs —
PPM010878 PGS002000
(portability-PLR_poorer_health)
 PSS008586|
Greater Middle Eastern Ancestry|
1,122 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.1069 [0.0482, 0.1649] sex, age, birth date, deprivation index, 16 PCs —
PPM010879 PGS002000
(portability-PLR_poorer_health)
 PSS008364|
South Asian Ancestry|
6,144 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.1182 [0.0935, 0.1429] sex, age, birth date, deprivation index, 16 PCs —
PPM010880 PGS002000
(portability-PLR_poorer_health)
 PSS008141|
East Asian Ancestry|
1,761 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.0587 [0.0117, 0.1054] sex, age, birth date, deprivation index, 16 PCs —
PPM010881 PGS002000
(portability-PLR_poorer_health)
 PSS007928|
African Ancestry|
2,438 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.083 [0.0432, 0.1224] sex, age, birth date, deprivation index, 16 PCs —
PPM010882 PGS002000
(portability-PLR_poorer_health)
 PSS009032|
African Ancestry|
3,784 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.0445 [0.0126, 0.0764] sex, age, birth date, deprivation index, 16 PCs —
PPM010906 PGS002004
(portability-PLR_sensitive_stomach)
 PSS009489|
European Ancestry|
6,619 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): 0.049 [0.0249, 0.073] sex, age, birth date, deprivation index, 16 PCs —
PPM010907 PGS002004
(portability-PLR_sensitive_stomach)
 PSS009263|
European Ancestry|
1,216 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): 0.0561 sex, age, birth date, deprivation index, 16 PCs —
PPM010908 PGS002004
(portability-PLR_sensitive_stomach)
 PSS008817|
European Ancestry|
2,231 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): -0.0333 [-0.0749, 0.0084] sex, age, birth date, deprivation index, 16 PCs —
PPM010910 PGS002004
(portability-PLR_sensitive_stomach)
 PSS008369|
South Asian Ancestry|
842 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): 0.0535 [-0.015, 0.1214] sex, age, birth date, deprivation index, 16 PCs —
PPM010911 PGS002004
(portability-PLR_sensitive_stomach)
 PSS008145|
East Asian Ancestry|
413 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): 0.0263 [-0.0728, 0.1249] sex, age, birth date, deprivation index, 16 PCs —
PPM010912 PGS002004
(portability-PLR_sensitive_stomach)
 PSS007933|
African Ancestry|
355 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): 0.046 [-0.0614, 0.1524] sex, age, birth date, deprivation index, 16 PCs —
PPM010913 PGS002004
(portability-PLR_sensitive_stomach)
 PSS009037|
African Ancestry|
479 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): 0.1057 [0.0143, 0.1954] sex, age, birth date, deprivation index, 16 PCs —
PPM010909 PGS002004
(portability-PLR_sensitive_stomach)
 PSS008591|
Greater Middle Eastern Ancestry|
196 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): -0.1061 [-0.2501, 0.0425] sex, age, birth date, deprivation index, 16 PCs —
PPM012591 PGS002218
(portability-ldpred2_poorer_health)
 PSS009484|
European Ancestry|
19,916 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.1836 [0.1702, 0.197] sex, age, birth date, deprivation index, 16 PCs —
PPM012592 PGS002218
(portability-ldpred2_poorer_health)
 PSS009258|
European Ancestry|
4,073 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.1633 [0.1332, 0.1932] sex, age, birth date, deprivation index, 16 PCs —
PPM012593 PGS002218
(portability-ldpred2_poorer_health)
 PSS008812|
European Ancestry|
6,579 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.1628 [0.1391, 0.1863] sex, age, birth date, deprivation index, 16 PCs —
PPM012594 PGS002218
(portability-ldpred2_poorer_health)
 PSS008586|
Greater Middle Eastern Ancestry|
1,122 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.1078 [0.0491, 0.1658] sex, age, birth date, deprivation index, 16 PCs —
PPM012595 PGS002218
(portability-ldpred2_poorer_health)
 PSS008364|
South Asian Ancestry|
6,144 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.1314 [0.1067, 0.1559] sex, age, birth date, deprivation index, 16 PCs —
PPM012596 PGS002218
(portability-ldpred2_poorer_health)
 PSS008141|
East Asian Ancestry|
1,761 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.0723 [0.0254, 0.1189] sex, age, birth date, deprivation index, 16 PCs —
PPM012597 PGS002218
(portability-ldpred2_poorer_health)
 PSS007928|
African Ancestry|
2,438 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.0718 [0.032, 0.1114] sex, age, birth date, deprivation index, 16 PCs —
PPM012598 PGS002218
(portability-ldpred2_poorer_health)
 PSS009032|
African Ancestry|
3,784 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Overall health rating — — Partial Correlation (partial-r): 0.0739 [0.0421, 0.1056] sex, age, birth date, deprivation index, 16 PCs —
PPM012630 PGS002223
(portability-ldpred2_sensitive_stomach)
 PSS009489|
European Ancestry|
6,619 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): 0.0922 [0.0682, 0.116] sex, age, birth date, deprivation index, 16 PCs —
PPM012631 PGS002223
(portability-ldpred2_sensitive_stomach)
 PSS009263|
European Ancestry|
1,216 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): 0.0905 [0.034, 0.1465] sex, age, birth date, deprivation index, 16 PCs —
PPM012632 PGS002223
(portability-ldpred2_sensitive_stomach)
 PSS008817|
European Ancestry|
2,231 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): 0.0032 [-0.0385, 0.0449] sex, age, birth date, deprivation index, 16 PCs —
PPM012633 PGS002223
(portability-ldpred2_sensitive_stomach)
 PSS008591|
Greater Middle Eastern Ancestry|
196 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): -0.0138 [-0.1614, 0.1344] sex, age, birth date, deprivation index, 16 PCs —
PPM012634 PGS002223
(portability-ldpred2_sensitive_stomach)
 PSS008369|
South Asian Ancestry|
842 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): 0.1276 [0.0597, 0.1942] sex, age, birth date, deprivation index, 16 PCs —
PPM012635 PGS002223
(portability-ldpred2_sensitive_stomach)
 PSS008145|
East Asian Ancestry|
413 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): 0.0012 [-0.0977, 0.1001] sex, age, birth date, deprivation index, 16 PCs —
PPM012636 PGS002223
(portability-ldpred2_sensitive_stomach)
 PSS007933|
African Ancestry|
355 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): 0.0978 [-0.0094, 0.2029] sex, age, birth date, deprivation index, 16 PCs —
PPM012637 PGS002223
(portability-ldpred2_sensitive_stomach)
 PSS009037|
African Ancestry|
479 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sensitive stomach — — Partial Correlation (partial-r): 0.0343 [-0.0574, 0.1254] sex, age, birth date, deprivation index, 16 PCs —
PPM017496 PGS003568
(cont-decay-sensitive_stomach)
 PSS010935|
European Ancestry|
6,703 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sensitive stomach — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM017580 PGS003568
(cont-decay-sensitive_stomach)
 PSS010851|
European Ancestry|
1,216 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sensitive stomach — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM017664 PGS003568
(cont-decay-sensitive_stomach)
 PSS010683|
European Ancestry|
2,159 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sensitive stomach — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM017748 PGS003568
(cont-decay-sensitive_stomach)
 PSS010599|
Greater Middle Eastern Ancestry|
196 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sensitive stomach — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM017832 PGS003568
(cont-decay-sensitive_stomach)
 PSS010263|
European Ancestry|
976 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sensitive stomach — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM017916 PGS003568
(cont-decay-sensitive_stomach)
 PSS010515|
South Asian Ancestry|
840 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sensitive stomach — — partial-R2: 0.02 sex, age, deprivation index, PC1-16 —
PPM018000 PGS003568
(cont-decay-sensitive_stomach)
 PSS010431|
East Asian Ancestry|
413 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sensitive stomach — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM018084 PGS003568
(cont-decay-sensitive_stomach)
 PSS010347|
African Ancestry|
355 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sensitive stomach — — partial-R2: 0.02 sex, age, deprivation index, PC1-16 —
PPM018168 PGS003568
(cont-decay-sensitive_stomach)
 PSS010767|
African Ancestry|
478 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sensitive stomach — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009032 — — 3,784 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008141 — — 1,761 individuals — East Asian China (East Asia) UKB —
PSS009037 — — 479 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008145 — — 413 individuals — East Asian China (East Asia) UKB —
PSS010935 — — 6,703 individuals,
45.0 % Male samples
 Mean = 56.2 years
Sd = 7.6 years		 European white British UKB —
PSS010683 — — 2,159 individuals,
42.0 % Male samples
 Mean = 54.1 years
Sd = 8.1 years		 European Italian UKB —
PSS010431 — — 413 individuals,
25.0 % Male samples
 Mean = 52.5 years
Sd = 7.2 years		 East Asian Chinese UKB —
PSS008812 — — 6,579 individuals — European Italy (South Europe) UKB —
PSS008817 — — 2,231 individuals — European Italy (South Europe) UKB —
PSS007928 — — 2,438 individuals — African American or Afro-Caribbean Carribean UKB —
PSS007933 — — 355 individuals — African American or Afro-Caribbean Carribean UKB —
PSS010851 — — 1,216 individuals,
34.0 % Male samples
 Mean = 54.1 years
Sd = 7.3 years		 European Polish UKB —
PSS008586 — — 1,122 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009484 — — 19,916 individuals — European UK (+ Ireland) UKB —
PSS010599 — — 196 individuals,
59.0 % Male samples
 Mean = 54.1 years
Sd = 7.5 years		 Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB —
PSS008591 — — 196 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009489 — — 6,619 individuals — European UK (+ Ireland) UKB —
PSS010347 — — 355 individuals,
33.0 % Male samples
 Mean = 50.7 years
Sd = 7.0 years		 African American or Afro-Caribbean Caribbean UKB —
PSS009258 — — 4,073 individuals — European Poland (NE Europe) UKB —
PSS008364 — — 6,144 individuals — South Asian India (South Asia) UKB —
PSS009263 — — 1,216 individuals — European Poland (NE Europe) UKB —
PSS008369 — — 842 individuals — South Asian India (South Asia) UKB —
PSS010767 — — 478 individuals,
46.0 % Male samples
 Mean = 50.7 years
Sd = 7.0 years		 African unspecified Nigerian UKB —
PSS010515 — — 840 individuals,
55.0 % Male samples
 Mean = 52.5 years
Sd = 8.3 years		 South Asian Indian UKB —
PSS010263 — — 976 individuals,
43.0 % Male samples
 Mean = 57.5 years
Sd = 6.9 years		 European Ashkenazi UKB —