Trait: health trait

Experimental Factor Ontology (EFO) Information
Identifier EFO_0007652
Description The characteristics in health that a certain person has.
Trait category
Other trait

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS002000
(portability-PLR_poorer_health)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Overall health rating health trait 53,716
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002000/ScoringFiles/PGS002000.txt.gz
PGS002004
(portability-PLR_sensitive_stomach)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Sensitive stomach health trait 3,970
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002004/ScoringFiles/PGS002004.txt.gz
PGS002218
(portability-ldpred2_poorer_health)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Overall health rating health trait 958,362
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002218/ScoringFiles/PGS002218.txt.gz
PGS002223
(portability-ldpred2_sensitive_stomach)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Sensitive stomach health trait 795,614
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002223/ScoringFiles/PGS002223.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010875 PGS002000
(portability-PLR_poorer_health)
PSS009484|
European Ancestry|
19,916 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.1677 [0.1542, 0.1812] sex, age, birth date, deprivation index, 16 PCs
PPM010876 PGS002000
(portability-PLR_poorer_health)
PSS009258|
European Ancestry|
4,073 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.1454 [0.1151, 0.1754] sex, age, birth date, deprivation index, 16 PCs
PPM010877 PGS002000
(portability-PLR_poorer_health)
PSS008812|
European Ancestry|
6,579 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.1449 [0.1212, 0.1686] sex, age, birth date, deprivation index, 16 PCs
PPM010878 PGS002000
(portability-PLR_poorer_health)
PSS008586|
Greater Middle Eastern Ancestry|
1,122 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.1069 [0.0482, 0.1649] sex, age, birth date, deprivation index, 16 PCs
PPM010879 PGS002000
(portability-PLR_poorer_health)
PSS008364|
South Asian Ancestry|
6,144 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.1182 [0.0935, 0.1429] sex, age, birth date, deprivation index, 16 PCs
PPM010880 PGS002000
(portability-PLR_poorer_health)
PSS008141|
East Asian Ancestry|
1,761 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.0587 [0.0117, 0.1054] sex, age, birth date, deprivation index, 16 PCs
PPM010881 PGS002000
(portability-PLR_poorer_health)
PSS007928|
African Ancestry|
2,438 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.083 [0.0432, 0.1224] sex, age, birth date, deprivation index, 16 PCs
PPM010882 PGS002000
(portability-PLR_poorer_health)
PSS009032|
African Ancestry|
3,784 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.0445 [0.0126, 0.0764] sex, age, birth date, deprivation index, 16 PCs
PPM010906 PGS002004
(portability-PLR_sensitive_stomach)
PSS009489|
European Ancestry|
6,619 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): 0.049 [0.0249, 0.073] sex, age, birth date, deprivation index, 16 PCs
PPM010907 PGS002004
(portability-PLR_sensitive_stomach)
PSS009263|
European Ancestry|
1,216 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): 0.0561 sex, age, birth date, deprivation index, 16 PCs
PPM010908 PGS002004
(portability-PLR_sensitive_stomach)
PSS008817|
European Ancestry|
2,231 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): -0.0333 [-0.0749, 0.0084] sex, age, birth date, deprivation index, 16 PCs
PPM010910 PGS002004
(portability-PLR_sensitive_stomach)
PSS008369|
South Asian Ancestry|
842 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): 0.0535 [-0.015, 0.1214] sex, age, birth date, deprivation index, 16 PCs
PPM010911 PGS002004
(portability-PLR_sensitive_stomach)
PSS008145|
East Asian Ancestry|
413 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): 0.0263 [-0.0728, 0.1249] sex, age, birth date, deprivation index, 16 PCs
PPM010912 PGS002004
(portability-PLR_sensitive_stomach)
PSS007933|
African Ancestry|
355 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): 0.046 [-0.0614, 0.1524] sex, age, birth date, deprivation index, 16 PCs
PPM010913 PGS002004
(portability-PLR_sensitive_stomach)
PSS009037|
African Ancestry|
479 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): 0.1057 [0.0143, 0.1954] sex, age, birth date, deprivation index, 16 PCs
PPM010909 PGS002004
(portability-PLR_sensitive_stomach)
PSS008591|
Greater Middle Eastern Ancestry|
196 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): -0.1061 [-0.2501, 0.0425] sex, age, birth date, deprivation index, 16 PCs
PPM012591 PGS002218
(portability-ldpred2_poorer_health)
PSS009484|
European Ancestry|
19,916 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.1836 [0.1702, 0.197] sex, age, birth date, deprivation index, 16 PCs
PPM012592 PGS002218
(portability-ldpred2_poorer_health)
PSS009258|
European Ancestry|
4,073 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.1633 [0.1332, 0.1932] sex, age, birth date, deprivation index, 16 PCs
PPM012593 PGS002218
(portability-ldpred2_poorer_health)
PSS008812|
European Ancestry|
6,579 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.1628 [0.1391, 0.1863] sex, age, birth date, deprivation index, 16 PCs
PPM012594 PGS002218
(portability-ldpred2_poorer_health)
PSS008586|
Greater Middle Eastern Ancestry|
1,122 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.1078 [0.0491, 0.1658] sex, age, birth date, deprivation index, 16 PCs
PPM012595 PGS002218
(portability-ldpred2_poorer_health)
PSS008364|
South Asian Ancestry|
6,144 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.1314 [0.1067, 0.1559] sex, age, birth date, deprivation index, 16 PCs
PPM012596 PGS002218
(portability-ldpred2_poorer_health)
PSS008141|
East Asian Ancestry|
1,761 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.0723 [0.0254, 0.1189] sex, age, birth date, deprivation index, 16 PCs
PPM012597 PGS002218
(portability-ldpred2_poorer_health)
PSS007928|
African Ancestry|
2,438 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.0718 [0.032, 0.1114] sex, age, birth date, deprivation index, 16 PCs
PPM012598 PGS002218
(portability-ldpred2_poorer_health)
PSS009032|
African Ancestry|
3,784 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overall health rating Partial Correlation (partial-r): 0.0739 [0.0421, 0.1056] sex, age, birth date, deprivation index, 16 PCs
PPM012630 PGS002223
(portability-ldpred2_sensitive_stomach)
PSS009489|
European Ancestry|
6,619 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): 0.0922 [0.0682, 0.116] sex, age, birth date, deprivation index, 16 PCs
PPM012631 PGS002223
(portability-ldpred2_sensitive_stomach)
PSS009263|
European Ancestry|
1,216 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): 0.0905 [0.034, 0.1465] sex, age, birth date, deprivation index, 16 PCs
PPM012632 PGS002223
(portability-ldpred2_sensitive_stomach)
PSS008817|
European Ancestry|
2,231 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): 0.0032 [-0.0385, 0.0449] sex, age, birth date, deprivation index, 16 PCs
PPM012633 PGS002223
(portability-ldpred2_sensitive_stomach)
PSS008591|
Greater Middle Eastern Ancestry|
196 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): -0.0138 [-0.1614, 0.1344] sex, age, birth date, deprivation index, 16 PCs
PPM012634 PGS002223
(portability-ldpred2_sensitive_stomach)
PSS008369|
South Asian Ancestry|
842 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): 0.1276 [0.0597, 0.1942] sex, age, birth date, deprivation index, 16 PCs
PPM012635 PGS002223
(portability-ldpred2_sensitive_stomach)
PSS008145|
East Asian Ancestry|
413 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): 0.0012 [-0.0977, 0.1001] sex, age, birth date, deprivation index, 16 PCs
PPM012636 PGS002223
(portability-ldpred2_sensitive_stomach)
PSS007933|
African Ancestry|
355 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): 0.0978 [-0.0094, 0.2029] sex, age, birth date, deprivation index, 16 PCs
PPM012637 PGS002223
(portability-ldpred2_sensitive_stomach)
PSS009037|
African Ancestry|
479 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sensitive stomach Partial Correlation (partial-r): 0.0343 [-0.0574, 0.1254] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009032 3,784 individuals African unspecified Nigeria (West Africa) UKB
PSS008586 1,122 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009258 4,073 individuals European Poland (NE Europe) UKB
PSS009484 19,916 individuals European UK (+ Ireland) UKB
PSS008812 6,579 individuals European Italy (South Europe) UKB
PSS008364 6,144 individuals South Asian India (South Asia) UKB
PSS008141 1,761 individuals East Asian China (East Asia) UKB
PSS009263 1,216 individuals European Poland (NE Europe) UKB
PSS009489 6,619 individuals European UK (+ Ireland) UKB
PSS008817 2,231 individuals European Italy (South Europe) UKB
PSS008369 842 individuals South Asian India (South Asia) UKB
PSS008145 413 individuals East Asian China (East Asia) UKB
PSS009037 479 individuals African unspecified Nigeria (West Africa) UKB
PSS008591 196 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS007928 2,438 individuals African American or Afro-Caribbean Carribean UKB
PSS007933 355 individuals African American or Afro-Caribbean Carribean UKB