Trait: age at first birth measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009101
Description A measurement of the age at which a woman gave birth to her first live child
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS001912
(portability-PLR_F_age_first_birth)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Age at first live birth age at first birth measurement 15,201
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001912/ScoringFiles/PGS001912.txt.gz
PGS002127
(portability-ldpred2_F_age_first_birth)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Age at first live birth age at first birth measurement 848,784
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002127/ScoringFiles/PGS002127.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010179 PGS001912
(portability-PLR_F_age_first_birth)
 PSS009371|
European Ancestry|
3,989 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): 0.1321 [0.1014, 0.1625] sex, age, birth date, deprivation index, 16 PCs —
PPM010180 PGS001912
(portability-PLR_F_age_first_birth)
 PSS009145|
European Ancestry|
768 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): 0.1462 [0.0753, 0.2156] sex, age, birth date, deprivation index, 16 PCs —
PPM010181 PGS001912
(portability-PLR_F_age_first_birth)
 PSS008699|
European Ancestry|
1,149 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): 0.0667 [0.0084, 0.1245] sex, age, birth date, deprivation index, 16 PCs —
PPM010182 PGS001912
(portability-PLR_F_age_first_birth)
 PSS008473|
Greater Middle Eastern Ancestry|
157 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): 0.0391 [-0.1289, 0.2048] sex, age, birth date, deprivation index, 16 PCs —
PPM010183 PGS001912
(portability-PLR_F_age_first_birth)
 PSS008251|
South Asian Ancestry|
1,185 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): 0.0506 [-0.0069, 0.1077] sex, age, birth date, deprivation index, 16 PCs —
PPM010185 PGS001912
(portability-PLR_F_age_first_birth)
 PSS007815|
African Ancestry|
509 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): -0.0326 [-0.1209, 0.0561] sex, age, birth date, deprivation index, 16 PCs —
PPM010186 PGS001912
(portability-PLR_F_age_first_birth)
 PSS008919|
African Ancestry|
746 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): 0.0133 [-0.0595, 0.0859] sex, age, birth date, deprivation index, 16 PCs —
PPM010184 PGS001912
(portability-PLR_F_age_first_birth)
 PSS008029|
East Asian Ancestry|
314 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): -0.0059 [-0.12, 0.1084] sex, age, birth date, deprivation index, 16 PCs —
PPM011872 PGS002127
(portability-ldpred2_F_age_first_birth)
 PSS009145|
European Ancestry|
768 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): 0.1972 [0.1273, 0.2652] sex, age, birth date, deprivation index, 16 PCs —
PPM011871 PGS002127
(portability-ldpred2_F_age_first_birth)
 PSS009371|
European Ancestry|
3,989 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): 0.1829 [0.1527, 0.2128] sex, age, birth date, deprivation index, 16 PCs —
PPM011873 PGS002127
(portability-ldpred2_F_age_first_birth)
 PSS008699|
European Ancestry|
1,149 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): 0.1779 [0.1208, 0.2338] sex, age, birth date, deprivation index, 16 PCs —
PPM011874 PGS002127
(portability-ldpred2_F_age_first_birth)
 PSS008473|
Greater Middle Eastern Ancestry|
157 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): 0.0501 [-0.118, 0.2154] sex, age, birth date, deprivation index, 16 PCs —
PPM011875 PGS002127
(portability-ldpred2_F_age_first_birth)
 PSS008251|
South Asian Ancestry|
1,185 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): 0.0625 [0.0051, 0.1195] sex, age, birth date, deprivation index, 16 PCs —
PPM011876 PGS002127
(portability-ldpred2_F_age_first_birth)
 PSS008029|
East Asian Ancestry|
314 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): -0.0711 [-0.1838, 0.0434] sex, age, birth date, deprivation index, 16 PCs —
PPM011877 PGS002127
(portability-ldpred2_F_age_first_birth)
 PSS007815|
African Ancestry|
509 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): 0.0076 [-0.081, 0.0961] sex, age, birth date, deprivation index, 16 PCs —
PPM011878 PGS002127
(portability-ldpred2_F_age_first_birth)
 PSS008919|
African Ancestry|
746 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Age at first live birth — — Partial Correlation (partial-r): 0.0199 [-0.0529, 0.0925] sex, age, birth date, deprivation index, 16 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS007815 — — 509 individuals — African American or Afro-Caribbean Carribean UKB —
PSS008699 — — 1,149 individuals — European Italy (South Europe) UKB —
PSS008919 — — 746 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008473 — — 157 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009145 — — 768 individuals — European Poland (NE Europe) UKB —
PSS008251 — — 1,185 individuals — South Asian India (South Asia) UKB —
PSS008029 — — 314 individuals — East Asian China (East Asia) UKB —
PSS009371 — — 3,989 individuals — European UK (+ Ireland) UKB —