Trait: health satisfaction measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009724
Description Quantification of health satisfaction.
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001008
(GBE_QT_FC1002178)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Overall health rating health satisfaction measurement 10,464
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001008/ScoringFiles/PGS001008.txt.gz
PGS001401
(GBE_QT_FC1004548)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Health satisfaction health satisfaction measurement 1,814
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001401/ScoringFiles/PGS001401.txt.gz
PGS001935
(portability-PLR_less_happy_with_health)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 General happiness with own health health satisfaction measurement 9,070
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001935/ScoringFiles/PGS001935.txt.gz
PGS002153
(portability-ldpred2_less_happy_with_health)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 General happiness with own health health satisfaction measurement 824,602
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002153/ScoringFiles/PGS002153.txt.gz
PGS003519
(cont-decay-less_happy_with_health)
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 General happiness with own health health satisfaction measurement 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003519/ScoringFiles/PGS003519.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007803 PGS001008
(GBE_QT_FC1002178)
 PSS007591|
African Ancestry|
6,303 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Overall health rating — — R²: 0.02094 [0.01405, 0.02782]
Incremental R2 (full-covars): -0.00287
PGS R2 (no covariates): 0.00121 [-0.00048, 0.0029]		 age, sex, UKB array type, Genotype PCs —
PPM007804 PGS001008
(GBE_QT_FC1002178)
 PSS007592|
East Asian Ancestry|
1,636 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Overall health rating — — R²: 0.01726 [0.00503, 0.0295]
Incremental R2 (full-covars): -0.00444
PGS R2 (no covariates): 0.00157 [-0.00218, 0.00533]		 age, sex, UKB array type, Genotype PCs —
PPM007805 PGS001008
(GBE_QT_FC1002178)
 PSS007593|
European Ancestry|
24,733 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Overall health rating — — R²: 0.03896 [0.03425, 0.04368]
Incremental R2 (full-covars): 0.01798
PGS R2 (no covariates): 0.02029 [0.01682, 0.02375]		 age, sex, UKB array type, Genotype PCs —
PPM007806 PGS001008
(GBE_QT_FC1002178)
 PSS007594|
South Asian Ancestry|
7,568 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Overall health rating — — R²: 0.02097 [0.01469, 0.02725]
Incremental R2 (full-covars): 0.00755
PGS R2 (no covariates): 0.00811 [0.00415, 0.01206]		 age, sex, UKB array type, Genotype PCs —
PPM007807 PGS001008
(GBE_QT_FC1002178)
 PSS007595|
European Ancestry|
67,195 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Overall health rating — — R²: 0.02852 [0.02605, 0.031]
Incremental R2 (full-covars): 0.01945
PGS R2 (no covariates): 0.02062 [0.0185, 0.02274]		 age, sex, UKB array type, Genotype PCs —
PPM007250 PGS001401
(GBE_QT_FC1004548)
 PSS007601|
African Ancestry|
3,770 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Health satisfaction — — R²: 0.01436 [0.00862, 0.0201]
Incremental R2 (full-covars): -0.00107
PGS R2 (no covariates): 0.00031 [-0.00055, 0.00117]		 age, sex, UKB array type, Genotype PCs —
PPM007251 PGS001401
(GBE_QT_FC1004548)
 PSS007602|
East Asian Ancestry|
773 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Health satisfaction — — R²: 0.01047 [0.00087, 0.02006]
Incremental R2 (full-covars): -0.00364
PGS R2 (no covariates): 0.0 [-0.0002, 0.00021]		 age, sex, UKB array type, Genotype PCs —
PPM007252 PGS001401
(GBE_QT_FC1004548)
 PSS007603|
European Ancestry|
10,834 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Health satisfaction — — R²: 0.01053 [0.00801, 0.01305]
Incremental R2 (full-covars): 0.00325
PGS R2 (no covariates): 0.00366 [0.00217, 0.00516]		 age, sex, UKB array type, Genotype PCs —
PPM007253 PGS001401
(GBE_QT_FC1004548)
 PSS007604|
South Asian Ancestry|
4,984 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Health satisfaction — — R²: 0.01007 [0.00567, 0.01447]
Incremental R2 (full-covars): -0.00147
PGS R2 (no covariates): 0.00014 [-0.00038, 0.00065]		 age, sex, UKB array type, Genotype PCs —
PPM007254 PGS001401
(GBE_QT_FC1004548)
 PSS007605|
European Ancestry|
26,439 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Health satisfaction — — R²: 0.00501 [0.00394, 0.00607]
Incremental R2 (full-covars): 0.00135
PGS R2 (no covariates): 0.00204 [0.00136, 0.00272]		 age, sex, UKB array type, Genotype PCs —
PPM010356 PGS001935
(portability-PLR_less_happy_with_health)
 PSS009197|
European Ancestry|
1,246 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0746 [0.0187, 0.1301] sex, age, birth date, deprivation index, 16 PCs —
PPM010357 PGS001935
(portability-PLR_less_happy_with_health)
 PSS008751|
European Ancestry|
2,257 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0562 [0.0148, 0.0975] sex, age, birth date, deprivation index, 16 PCs —
PPM010358 PGS001935
(portability-PLR_less_happy_with_health)
 PSS008525|
Greater Middle Eastern Ancestry|
199 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): -0.0096 [-0.156, 0.1373] sex, age, birth date, deprivation index, 16 PCs —
PPM010359 PGS001935
(portability-PLR_less_happy_with_health)
 PSS008303|
South Asian Ancestry|
815 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0029 [-0.0667, 0.0724] sex, age, birth date, deprivation index, 16 PCs —
PPM010360 PGS001935
(portability-PLR_less_happy_with_health)
 PSS008080|
East Asian Ancestry|
423 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): -0.0063 [-0.1039, 0.0915] sex, age, birth date, deprivation index, 16 PCs —
PPM010361 PGS001935
(portability-PLR_less_happy_with_health)
 PSS007867|
African Ancestry|
374 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0167 [-0.0877, 0.1207] sex, age, birth date, deprivation index, 16 PCs —
PPM010362 PGS001935
(portability-PLR_less_happy_with_health)
 PSS008971|
African Ancestry|
511 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0279 [-0.0607, 0.1161] sex, age, birth date, deprivation index, 16 PCs —
PPM010355 PGS001935
(portability-PLR_less_happy_with_health)
 PSS009423|
European Ancestry|
6,445 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.064 [0.0396, 0.0883] sex, age, birth date, deprivation index, 16 PCs —
PPM012075 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS008303|
South Asian Ancestry|
815 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0875 [0.0181, 0.1561] sex, age, birth date, deprivation index, 16 PCs —
PPM012071 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS009423|
European Ancestry|
6,445 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.1032 [0.0789, 0.1273] sex, age, birth date, deprivation index, 16 PCs —
PPM012072 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS009197|
European Ancestry|
1,246 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.119 [0.0634, 0.1738] sex, age, birth date, deprivation index, 16 PCs —
PPM012073 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS008751|
European Ancestry|
2,257 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0596 [0.0182, 0.1008] sex, age, birth date, deprivation index, 16 PCs —
PPM012074 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS008525|
Greater Middle Eastern Ancestry|
199 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0755 [-0.072, 0.2197] sex, age, birth date, deprivation index, 16 PCs —
PPM012076 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS008080|
East Asian Ancestry|
423 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0795 [-0.0183, 0.1759] sex, age, birth date, deprivation index, 16 PCs —
PPM012077 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS007867|
African Ancestry|
374 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): -0.046 [-0.1495, 0.0585] sex, age, birth date, deprivation index, 16 PCs —
PPM012078 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS008971|
African Ancestry|
511 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0167 [-0.0719, 0.105] sex, age, birth date, deprivation index, 16 PCs —
PPM017447 PGS003519
(cont-decay-less_happy_with_health)
 PSS010882|
European Ancestry|
6,496 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: General happiness with own health — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM017531 PGS003519
(cont-decay-less_happy_with_health)
 PSS010798|
European Ancestry|
1,246 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: General happiness with own health — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM017699 PGS003519
(cont-decay-less_happy_with_health)
 PSS010546|
Greater Middle Eastern Ancestry|
199 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: General happiness with own health — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM017783 PGS003519
(cont-decay-less_happy_with_health)
 PSS010210|
European Ancestry|
948 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: General happiness with own health — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM017867 PGS003519
(cont-decay-less_happy_with_health)
 PSS010462|
South Asian Ancestry|
815 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: General happiness with own health — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM017951 PGS003519
(cont-decay-less_happy_with_health)
 PSS010378|
East Asian Ancestry|
424 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: General happiness with own health — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM018035 PGS003519
(cont-decay-less_happy_with_health)
 PSS010294|
African Ancestry|
374 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: General happiness with own health — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM018119 PGS003519
(cont-decay-less_happy_with_health)
 PSS010714|
African Ancestry|
510 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: General happiness with own health — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM017615 PGS003519
(cont-decay-less_happy_with_health)
 PSS010630|
European Ancestry|
2,183 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: General happiness with own health — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008525 — — 199 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009423 — — 6,445 individuals — European UK (+ Ireland) UKB —
PSS010798 — — 1,246 individuals,
34.0 % Male samples
 Mean = 54.0 years
Sd = 7.2 years		 European Polish UKB —
PSS010546 — — 199 individuals,
56.0 % Male samples
 Mean = 54.0 years
Sd = 7.3 years		 Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB —
PSS010294 — — 374 individuals,
31.0 % Male samples
 Mean = 50.4 years
Sd = 7.3 years		 African American or Afro-Caribbean Caribbean UKB —
PSS009197 — — 1,246 individuals — European Poland (NE Europe) UKB —
PSS008303 — — 815 individuals — South Asian India (South Asia) UKB —
PSS010714 — — 510 individuals,
48.0 % Male samples
 Mean = 50.6 years
Sd = 7.2 years		 African unspecified Nigerian UKB —
PSS010462 — — 815 individuals,
57.0 % Male samples
 Mean = 52.6 years
Sd = 8.2 years		 South Asian Indian UKB —
PSS010210 — — 948 individuals,
43.0 % Male samples
 Mean = 57.6 years
Sd = 7.0 years		 European Ashkenazi UKB —
PSS008971 — — 511 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008080 — — 423 individuals — East Asian China (East Asia) UKB —
PSS007603 — — 10,834 individuals — European non-white British ancestry UKB —
PSS010882 — — 6,496 individuals,
45.0 % Male samples
 Mean = 56.2 years
Sd = 7.6 years		 European white British UKB —
PSS010630 — — 2,183 individuals,
41.0 % Male samples
 Mean = 53.9 years
Sd = 8.1 years		 European Italian UKB —
PSS007591 — — 6,303 individuals — African unspecified — UKB —
PSS007592 — — 1,636 individuals — East Asian — UKB —
PSS007593 — — 24,733 individuals — European non-white British ancestry UKB —
PSS007594 — — 7,568 individuals — South Asian — UKB —
PSS007595 — — 67,195 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS008751 — — 2,257 individuals — European Italy (South Europe) UKB —
PSS010378 — — 424 individuals,
26.0 % Male samples
 Mean = 52.3 years
Sd = 7.3 years		 East Asian Chinese UKB —
PSS007601 — — 3,770 individuals — African unspecified — UKB —
PSS007602 — — 773 individuals — East Asian — UKB —
PSS007867 — — 374 individuals — African American or Afro-Caribbean Carribean UKB —
PSS007604 — — 4,984 individuals — South Asian — UKB —
PSS007605 — — 26,439 individuals — European white British ancestry UKB Testing cohort (heldout set)