| Experimental Factor Ontology (EFO) Information | |
| Identifier | EFO_0009724 |
| Description | Quantification of health satisfaction. | Trait category |
Other measurement
|
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS001008 (GBE_QT_FC1002178) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Overall health rating | health satisfaction measurement | 10,464 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001008/ScoringFiles/PGS001008.txt.gz |
| PGS001401 (GBE_QT_FC1004548) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Health satisfaction | health satisfaction measurement | 1,814 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001401/ScoringFiles/PGS001401.txt.gz |
| PGS001935 (portability-PLR_less_happy_with_health) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
General happiness with own health | health satisfaction measurement | 9,070 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001935/ScoringFiles/PGS001935.txt.gz |
| PGS002153 (portability-ldpred2_less_happy_with_health) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
General happiness with own health | health satisfaction measurement | 824,602 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002153/ScoringFiles/PGS002153.txt.gz |
| PGS003519 (cont-decay-less_happy_with_health) |
PGP000457 | Ding Y et al. Nature (2023) |
General happiness with own health | health satisfaction measurement | 979,739 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003519/ScoringFiles/PGS003519.txt.gz |
|
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM007803 | PGS001008 (GBE_QT_FC1002178) |
PSS007591| African Ancestry| 6,303 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Overall health rating | — | — | R²: 0.02094 [0.01405, 0.02782] Incremental R2 (full-covars): -0.00287 PGS R2 (no covariates): 0.00121 [-0.00048, 0.0029] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007804 | PGS001008 (GBE_QT_FC1002178) |
PSS007592| East Asian Ancestry| 1,636 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Overall health rating | — | — | R²: 0.01726 [0.00503, 0.0295] Incremental R2 (full-covars): -0.00444 PGS R2 (no covariates): 0.00157 [-0.00218, 0.00533] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007805 | PGS001008 (GBE_QT_FC1002178) |
PSS007593| European Ancestry| 24,733 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Overall health rating | — | — | R²: 0.03896 [0.03425, 0.04368] Incremental R2 (full-covars): 0.01798 PGS R2 (no covariates): 0.02029 [0.01682, 0.02375] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007806 | PGS001008 (GBE_QT_FC1002178) |
PSS007594| South Asian Ancestry| 7,568 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Overall health rating | — | — | R²: 0.02097 [0.01469, 0.02725] Incremental R2 (full-covars): 0.00755 PGS R2 (no covariates): 0.00811 [0.00415, 0.01206] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007807 | PGS001008 (GBE_QT_FC1002178) |
PSS007595| European Ancestry| 67,195 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Overall health rating | — | — | R²: 0.02852 [0.02605, 0.031] Incremental R2 (full-covars): 0.01945 PGS R2 (no covariates): 0.02062 [0.0185, 0.02274] |
age, sex, UKB array type, Genotype PCs | — |
| PPM038324 | PGS001008 (GBE_QT_FC1002178) |
PSS013916| European Ancestry| 425,240 individuals |
PGP000865 | Bhatt IS et al. J Assoc Res Otolaryngol (2024) |Ext. |
Reported Trait: Age-related hearing difficulty | β: -0.0987 | — | — | — | — |
| PPM007250 | PGS001401 (GBE_QT_FC1004548) |
PSS007601| African Ancestry| 3,770 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Health satisfaction | — | — | R²: 0.01436 [0.00862, 0.0201] Incremental R2 (full-covars): -0.00107 PGS R2 (no covariates): 0.00031 [-0.00055, 0.00117] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007251 | PGS001401 (GBE_QT_FC1004548) |
PSS007602| East Asian Ancestry| 773 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Health satisfaction | — | — | R²: 0.01047 [0.00087, 0.02006] Incremental R2 (full-covars): -0.00364 PGS R2 (no covariates): 0.0 [-0.0002, 0.00021] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007252 | PGS001401 (GBE_QT_FC1004548) |
PSS007603| European Ancestry| 10,834 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Health satisfaction | — | — | R²: 0.01053 [0.00801, 0.01305] Incremental R2 (full-covars): 0.00325 PGS R2 (no covariates): 0.00366 [0.00217, 0.00516] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007253 | PGS001401 (GBE_QT_FC1004548) |
PSS007604| South Asian Ancestry| 4,984 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Health satisfaction | — | — | R²: 0.01007 [0.00567, 0.01447] Incremental R2 (full-covars): -0.00147 PGS R2 (no covariates): 0.00014 [-0.00038, 0.00065] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007254 | PGS001401 (GBE_QT_FC1004548) |
PSS007605| European Ancestry| 26,439 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Health satisfaction | — | — | R²: 0.00501 [0.00394, 0.00607] Incremental R2 (full-covars): 0.00135 PGS R2 (no covariates): 0.00204 [0.00136, 0.00272] |
age, sex, UKB array type, Genotype PCs | — |
| PPM038410 | PGS001401 (GBE_QT_FC1004548) |
PSS013916| European Ancestry| 425,240 individuals |
PGP000865 | Bhatt IS et al. J Assoc Res Otolaryngol (2024) |Ext. |
Reported Trait: Age-related hearing difficulty | β: 0.04839 | — | — | — | — |
| PPM010356 | PGS001935 (portability-PLR_less_happy_with_health) |
PSS009197| European Ancestry| 1,246 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): 0.0746 [0.0187, 0.1301] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010357 | PGS001935 (portability-PLR_less_happy_with_health) |
PSS008751| European Ancestry| 2,257 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): 0.0562 [0.0148, 0.0975] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010358 | PGS001935 (portability-PLR_less_happy_with_health) |
PSS008525| Greater Middle Eastern Ancestry| 199 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): -0.0096 [-0.156, 0.1373] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010359 | PGS001935 (portability-PLR_less_happy_with_health) |
PSS008303| South Asian Ancestry| 815 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): 0.0029 [-0.0667, 0.0724] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010360 | PGS001935 (portability-PLR_less_happy_with_health) |
PSS008080| East Asian Ancestry| 423 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): -0.0063 [-0.1039, 0.0915] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010361 | PGS001935 (portability-PLR_less_happy_with_health) |
PSS007867| African Ancestry| 374 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): 0.0167 [-0.0877, 0.1207] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010362 | PGS001935 (portability-PLR_less_happy_with_health) |
PSS008971| African Ancestry| 511 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): 0.0279 [-0.0607, 0.1161] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010355 | PGS001935 (portability-PLR_less_happy_with_health) |
PSS009423| European Ancestry| 6,445 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): 0.064 [0.0396, 0.0883] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM038404 | PGS001935 (portability-PLR_less_happy_with_health) |
PSS013916| European Ancestry| 425,240 individuals |
PGP000865 | Bhatt IS et al. J Assoc Res Otolaryngol (2024) |Ext. |
Reported Trait: Age-related hearing difficulty | β: 0.04982 | — | — | — | — |
| PPM012075 | PGS002153 (portability-ldpred2_less_happy_with_health) |
PSS008303| South Asian Ancestry| 815 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): 0.0875 [0.0181, 0.1561] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012071 | PGS002153 (portability-ldpred2_less_happy_with_health) |
PSS009423| European Ancestry| 6,445 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): 0.1032 [0.0789, 0.1273] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012072 | PGS002153 (portability-ldpred2_less_happy_with_health) |
PSS009197| European Ancestry| 1,246 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): 0.119 [0.0634, 0.1738] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012073 | PGS002153 (portability-ldpred2_less_happy_with_health) |
PSS008751| European Ancestry| 2,257 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): 0.0596 [0.0182, 0.1008] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012074 | PGS002153 (portability-ldpred2_less_happy_with_health) |
PSS008525| Greater Middle Eastern Ancestry| 199 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): 0.0755 [-0.072, 0.2197] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012076 | PGS002153 (portability-ldpred2_less_happy_with_health) |
PSS008080| East Asian Ancestry| 423 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): 0.0795 [-0.0183, 0.1759] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012077 | PGS002153 (portability-ldpred2_less_happy_with_health) |
PSS007867| African Ancestry| 374 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): -0.046 [-0.1495, 0.0585] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012078 | PGS002153 (portability-ldpred2_less_happy_with_health) |
PSS008971| African Ancestry| 511 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: General happiness with own health | — | — | Partial Correlation (partial-r): 0.0167 [-0.0719, 0.105] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM038327 | PGS002153 (portability-ldpred2_less_happy_with_health) |
PSS013916| European Ancestry| 425,240 individuals |
PGP000865 | Bhatt IS et al. J Assoc Res Otolaryngol (2024) |Ext. |
Reported Trait: Age-related hearing difficulty | β: 0.09184 | — | — | — | — |
| PPM017447 | PGS003519 (cont-decay-less_happy_with_health) |
PSS010882| European Ancestry| 6,496 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: General happiness with own health | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
| PPM017531 | PGS003519 (cont-decay-less_happy_with_health) |
PSS010798| European Ancestry| 1,246 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: General happiness with own health | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
| PPM017699 | PGS003519 (cont-decay-less_happy_with_health) |
PSS010546| Greater Middle Eastern Ancestry| 199 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: General happiness with own health | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
| PPM017783 | PGS003519 (cont-decay-less_happy_with_health) |
PSS010210| European Ancestry| 948 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: General happiness with own health | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
| PPM017867 | PGS003519 (cont-decay-less_happy_with_health) |
PSS010462| South Asian Ancestry| 815 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: General happiness with own health | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
| PPM017951 | PGS003519 (cont-decay-less_happy_with_health) |
PSS010378| East Asian Ancestry| 424 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: General happiness with own health | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
| PPM018035 | PGS003519 (cont-decay-less_happy_with_health) |
PSS010294| African Ancestry| 374 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: General happiness with own health | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
| PPM018119 | PGS003519 (cont-decay-less_happy_with_health) |
PSS010714| African Ancestry| 510 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: General happiness with own health | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
| PPM017615 | PGS003519 (cont-decay-less_happy_with_health) |
PSS010630| European Ancestry| 2,183 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: General happiness with own health | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
|
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS008525 | — | — | 199 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS009423 | — | — | 6,445 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS010798 | — | — | 1,246 individuals, 34.0 % Male samples |
Mean = 54.0 years Sd = 7.2 years |
European | Polish | UKB | — |
| PSS010546 | — | — | 199 individuals, 56.0 % Male samples |
Mean = 54.0 years Sd = 7.3 years |
Greater Middle Eastern (Middle Eastern, North African or Persian) | Iranian | UKB | — |
| PSS010294 | — | — | 374 individuals, 31.0 % Male samples |
Mean = 50.4 years Sd = 7.3 years |
African American or Afro-Caribbean | Caribbean | UKB | — |
| PSS009197 | — | — | 1,246 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS008303 | — | — | 815 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS010714 | — | — | 510 individuals, 48.0 % Male samples |
Mean = 50.6 years Sd = 7.2 years |
African unspecified | Nigerian | UKB | — |
| PSS010462 | — | — | 815 individuals, 57.0 % Male samples |
Mean = 52.6 years Sd = 8.2 years |
South Asian | Indian | UKB | — |
| PSS010210 | — | — | 948 individuals, 43.0 % Male samples |
Mean = 57.6 years Sd = 7.0 years |
European | Ashkenazi | UKB | — |
| PSS008971 | — | — | 511 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS008080 | — | — | 423 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS007603 | — | — | 10,834 individuals | — | European | non-white British ancestry | UKB | — |
| PSS010882 | — | — | 6,496 individuals, 45.0 % Male samples |
Mean = 56.2 years Sd = 7.6 years |
European | white British | UKB | — |
| PSS010630 | — | — | 2,183 individuals, 41.0 % Male samples |
Mean = 53.9 years Sd = 8.1 years |
European | Italian | UKB | — |
| PSS007591 | — | — | 6,303 individuals | — | African unspecified | — | UKB | — |
| PSS007592 | — | — | 1,636 individuals | — | East Asian | — | UKB | — |
| PSS007593 | — | — | 24,733 individuals | — | European | non-white British ancestry | UKB | — |
| PSS007594 | — | — | 7,568 individuals | — | South Asian | — | UKB | — |
| PSS007595 | — | — | 67,195 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS008751 | — | — | 2,257 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS010378 | — | — | 424 individuals, 26.0 % Male samples |
Mean = 52.3 years Sd = 7.3 years |
East Asian | Chinese | UKB | — |
| PSS007601 | — | — | 3,770 individuals | — | African unspecified | — | UKB | — |
| PSS007602 | — | — | 773 individuals | — | East Asian | — | UKB | — |
| PSS007867 | — | — | 374 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS007604 | — | — | 4,984 individuals | — | South Asian | — | UKB | — |
| PSS007605 | — | — | 26,439 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS013916 | — | — | [ ,
46.21 % Male samples |
— | European (British, Irish) |
— | UKB | — |