Trait: mucositis

Experimental Factor Ontology (EFO) Information
Identifier EFO_1001898
Description Mucositis is inflammation and damage of the mucous membranes lining the mouth and other parts of the gastrointestinal (GI) tract.
Trait category
Other trait

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS019325
(TPMI_528.1_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Stomatitis and mucositis mucositis 724,006
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019325/ScoringFiles/PGS019325.txt.gz
PGS019326
(TPMI_528.1_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Stomatitis and mucositis mucositis 939,884
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019326/ScoringFiles/PGS019326.txt.gz
PGS019327
(TPMI_528.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Stomatitis and mucositis mucositis 9,831
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019327/ScoringFiles/PGS019327.txt.gz
PGS019328
(TPMI_528.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Stomatitis and mucositis mucositis 983,821
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019328/ScoringFiles/PGS019328.txt.gz
PGS019329
(TPMI_528.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Stomatitis and mucositis mucositis 953,174
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019329/ScoringFiles/PGS019329.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM037507 PGS019325
(TPMI_528.1_Lassosum2)
 PSS013228|
East Asian Ancestry|
18,763 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Stomatitis and mucositis — AUROC: 0.61841 R²: 0.02732 sex, age, array, PCs 1-10 —
PPM037508 PGS019326
(TPMI_528.1_LDpred2)
 PSS013227|
East Asian Ancestry|
18,763 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Stomatitis and mucositis — AUROC: 0.62114 R²: 0.02851 sex, age, array, PCs 1-10 —
PPM037509 PGS019327
(TPMI_528.1_MegaPRS)
 PSS013229|
East Asian Ancestry|
18,763 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Stomatitis and mucositis — AUROC: 0.61821 R²: 0.02721 sex, age, array, PCs 1-10 —
PPM037510 PGS019328
(TPMI_528.1_PRS-CS)
 PSS013230|
East Asian Ancestry|
18,763 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Stomatitis and mucositis — AUROC: 0.62036 R²: 0.02826 sex, age, array, PCs 1-10 —
PPM037511 PGS019329
(TPMI_528.1_SBayesR)
 PSS013231|
East Asian Ancestry|
18,763 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Stomatitis and mucositis — AUROC: 0.61964 R²: 0.0275 sex, age, array, PCs 1-10 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013227 528.0, 528.2,K12.0, K12.1, K12.30, K12.39 —
[
  • 614 cases
  • , 18,149 controls
]
,
45.42 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013228 528.0, 528.2,K12.0, K12.1, K12.30, K12.39 —
[
  • 614 cases
  • , 18,149 controls
]
,
45.42 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013229 528.0, 528.2,K12.0, K12.1, K12.30, K12.39 —
[
  • 614 cases
  • , 18,149 controls
]
,
45.42 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013230 528.0, 528.2,K12.0, K12.1, K12.30, K12.39 —
[
  • 614 cases
  • , 18,149 controls
]
,
45.42 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013231 528.0, 528.2,K12.0, K12.1, K12.30, K12.39 —
[
  • 614 cases
  • , 18,149 controls
]
,
45.42 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —