Trait: Microscopic hematuria

Trait Information
Identifier HP_0002907
Description Microscopic hematuria detected by dipstick or microscopic examination of the urine.
Trait category
Other trait
Synonyms 3 synonyms
  • Microhematuria
  • Occult hematuria
  • Small amount of blood in urine

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS019468
(TPMI_593.2_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Microscopic hematuria Microscopic hematuria 294,454
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019468/ScoringFiles/PGS019468.txt.gz
PGS019469
(TPMI_593.2_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Microscopic hematuria Microscopic hematuria 939,824
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019469/ScoringFiles/PGS019469.txt.gz
PGS019470
(TPMI_593.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Microscopic hematuria Microscopic hematuria 40,557
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019470/ScoringFiles/PGS019470.txt.gz
PGS019471
(TPMI_593.2_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Microscopic hematuria Microscopic hematuria 983,778
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019471/ScoringFiles/PGS019471.txt.gz
PGS019472
(TPMI_593.2_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Microscopic hematuria Microscopic hematuria 1,005,807
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019472/ScoringFiles/PGS019472.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM037650 PGS019468
(TPMI_593.2_Lassosum2)
 PSS013366|
East Asian Ancestry|
16,818 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Microscopic hematuria — AUROC: 0.6893 R²: 0.00698 sex, age, array, PCs 1-10 —
PPM037651 PGS019469
(TPMI_593.2_LDpred2)
 PSS013365|
East Asian Ancestry|
16,818 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Microscopic hematuria — AUROC: 0.68835 R²: 0.00696 sex, age, array, PCs 1-10 —
PPM037652 PGS019470
(TPMI_593.2_MegaPRS)
 PSS013367|
East Asian Ancestry|
16,818 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Microscopic hematuria — AUROC: 0.6884 R²: 0.00695 sex, age, array, PCs 1-10 —
PPM037653 PGS019471
(TPMI_593.2_PRS-CS)
 PSS013368|
East Asian Ancestry|
16,818 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Microscopic hematuria — AUROC: 0.68854 R²: 0.00697 sex, age, array, PCs 1-10 —
PPM037654 PGS019472
(TPMI_593.2_SBayesR)
 PSS013369|
East Asian Ancestry|
16,818 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Microscopic hematuria — AUROC: 0.68844 R²: 0.00694 sex, age, array, PCs 1-10 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013365 599.72,R31.1, R31.2 —
[
  • 126 cases
  • , 16,692 controls
]
,
48.18 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013366 599.72,R31.1, R31.2 —
[
  • 126 cases
  • , 16,692 controls
]
,
48.18 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013367 599.72,R31.1, R31.2 —
[
  • 126 cases
  • , 16,692 controls
]
,
48.18 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013368 599.72,R31.1, R31.2 —
[
  • 126 cases
  • , 16,692 controls
]
,
48.18 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013369 599.72,R31.1, R31.2 —
[
  • 126 cases
  • , 16,692 controls
]
,
48.18 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —