Trait: Fasciitis

Trait Information
Identifier HP_0100537
Description Inflammation of fascia, the tissue under the skin and over the muscle.
Trait category
Other trait
Synonym Inflammation of the fascia

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS019712
(TPMI_728.7_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Fasciitis Fasciitis 347,287
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019712/ScoringFiles/PGS019712.txt.gz
PGS019713
(TPMI_728.7_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Fasciitis Fasciitis 939,862
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019713/ScoringFiles/PGS019713.txt.gz
PGS019714
(TPMI_728.7_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Fasciitis Fasciitis 460,281
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019714/ScoringFiles/PGS019714.txt.gz
PGS019715
(TPMI_728.7_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Fasciitis Fasciitis 983,805
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019715/ScoringFiles/PGS019715.txt.gz
PGS019716
(TPMI_728.7_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Fasciitis Fasciitis 990,026
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019716/ScoringFiles/PGS019716.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM037894 PGS019712
(TPMI_728.7_Lassosum2)
 PSS013610|
East Asian Ancestry|
15,061 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Fasciitis — AUROC: 0.6839 R²: 0.05791 sex, age, array, PCs 1-10 —
PPM037895 PGS019713
(TPMI_728.7_LDpred2)
 PSS013609|
East Asian Ancestry|
15,061 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Fasciitis — AUROC: 0.68444 R²: 0.05923 sex, age, array, PCs 1-10 —
PPM037896 PGS019714
(TPMI_728.7_MegaPRS)
 PSS013611|
East Asian Ancestry|
15,061 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Fasciitis — AUROC: 0.68579 R²: 0.05984 sex, age, array, PCs 1-10 —
PPM037897 PGS019715
(TPMI_728.7_PRS-CS)
 PSS013612|
East Asian Ancestry|
15,061 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Fasciitis — AUROC: 0.68426 R²: 0.05806 sex, age, array, PCs 1-10 —
PPM037898 PGS019716
(TPMI_728.7_SBayesR)
 PSS013613|
East Asian Ancestry|
15,061 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Fasciitis — AUROC: 0.68351 R²: 0.05765 sex, age, array, PCs 1-10 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013609 728.6, 728.71, 729.4,M72.0, M72.2, M72.9 —
[
  • 371 cases
  • , 14,690 controls
]
,
47.86 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013610 728.6, 728.71, 729.4,M72.0, M72.2, M72.9 —
[
  • 371 cases
  • , 14,690 controls
]
,
47.86 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013611 728.6, 728.71, 729.4,M72.0, M72.2, M72.9 —
[
  • 371 cases
  • , 14,690 controls
]
,
47.86 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013612 728.6, 728.71, 729.4,M72.0, M72.2, M72.9 —
[
  • 371 cases
  • , 14,690 controls
]
,
47.86 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013613 728.6, 728.71, 729.4,M72.0, M72.2, M72.9 —
[
  • 371 cases
  • , 14,690 controls
]
,
47.86 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —