Trait: overnutrition

Trait Information
Identifier MONDO_0003916
Description An imbalanced nutritional status resulting from excessive intake of nutrients. Generally, overnutrition generates an energy imbalance between food consumption and energy expenditure leading to disorders such as obesity. [MESH: D044343]
Trait category
Metabolic disorder
Mapped terms 5 mapped terms
  • DOID:654
  • ICD9:278.8
  • MESH:D044343
  • SCTID:302872003
  • UMLS:C1257763
Child trait(s) obesity

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "overnutrition" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS001298
(GBE_HC689)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Obesity (time-to-event) obesity 9,227
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001298/ScoringFiles/PGS001298.txt.gz
PGS001825
(portability-PLR_278)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Overweight, obesity and other hyperalimentation obesity,
overweight body mass index status,
overnutrition
13,009
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001825/ScoringFiles/PGS001825.txt.gz
PGS002033
(portability-ldpred2_278)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Overweight, obesity and other hyperalimentation obesity,
overweight body mass index status,
overnutrition
846,292
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002033/ScoringFiles/PGS002033.txt.gz
PGS003400
(PRS97_obesity)
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Obesity obesity 97
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003400/ScoringFiles/PGS003400.txt.gz
PGS003959
(GRS940_obesity)
PGP000507 |
Liu X et al. Clin Nutr (2023)
Obesity obesity 940
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003959/ScoringFiles/PGS003959.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM008987 PGS001298
(GBE_HC689)
PSS004590|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE obesity AUROC: 0.631 [0.60757, 0.65443] : 0.03591
Incremental AUROC (full-covars): -0.00374
PGS R2 (no covariates): 0.00346
PGS AUROC (no covariates): 0.54117 [0.51549, 0.56685]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008988 PGS001298
(GBE_HC689)
PSS004591|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE obesity AUROC: 0.65328 [0.53612, 0.77044] : 0.04232
Incremental AUROC (full-covars): -0.00574
PGS R2 (no covariates): 0.00287
PGS AUROC (no covariates): 0.54699 [0.43971, 0.65426]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008989 PGS001298
(GBE_HC689)
PSS004592|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE obesity AUROC: 0.59854 [0.58297, 0.61411] : 0.01902
Incremental AUROC (full-covars): 0.02082
PGS R2 (no covariates): 0.00911
PGS AUROC (no covariates): 0.56858 [0.5529, 0.58426]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008990 PGS001298
(GBE_HC689)
PSS004593|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE obesity AUROC: 0.61415 [0.59079, 0.6375] : 0.02737
Incremental AUROC (full-covars): 0.00377
PGS R2 (no covariates): 0.00603
PGS AUROC (no covariates): 0.55658 [0.53218, 0.58097]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008991 PGS001298
(GBE_HC689)
PSS004594|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE obesity AUROC: 0.59555 [0.58697, 0.60413] : 0.01814
Incremental AUROC (full-covars): 0.03355
PGS R2 (no covariates): 0.01146
PGS AUROC (no covariates): 0.57573 [0.56713, 0.58434]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009497 PGS001825
(portability-PLR_278)
PSS009295|
European Ancestry|
20,000 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0547 [0.0409, 0.0686] sex, age, birth date, deprivation index, 16 PCs
PPM009499 PGS001825
(portability-PLR_278)
PSS008623|
European Ancestry|
6,660 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0516 [0.0276, 0.0756] sex, age, birth date, deprivation index, 16 PCs
PPM009500 PGS001825
(portability-PLR_278)
PSS008398|
Greater Middle Eastern Ancestry|
1,200 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0493 [-0.0078, 0.106] sex, age, birth date, deprivation index, 16 PCs
PPM009501 PGS001825
(portability-PLR_278)
PSS008177|
South Asian Ancestry|
6,331 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0334 [0.0087, 0.058] sex, age, birth date, deprivation index, 16 PCs
PPM009502 PGS001825
(portability-PLR_278)
PSS007963|
East Asian Ancestry|
1,810 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): -0.0049 [-0.0513, 0.0414] sex, age, birth date, deprivation index, 16 PCs
PPM009503 PGS001825
(portability-PLR_278)
PSS007744|
African Ancestry|
2,484 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0323 [-0.0072, 0.0717] sex, age, birth date, deprivation index, 16 PCs
PPM009504 PGS001825
(portability-PLR_278)
PSS008848|
African Ancestry|
3,924 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0208 [-0.0105, 0.0522] sex, age, birth date, deprivation index, 16 PCs
PPM009498 PGS001825
(portability-PLR_278)
PSS009069|
European Ancestry|
4,136 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0453 [0.0148, 0.0758] sex, age, birth date, deprivation index, 16 PCs
PPM011135 PGS002033
(portability-ldpred2_278)
PSS009295|
European Ancestry|
20,000 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0789 [0.0651, 0.0927] sex, age, birth date, deprivation index, 16 PCs
PPM011137 PGS002033
(portability-ldpred2_278)
PSS008623|
European Ancestry|
6,660 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0824 [0.0585, 0.1062] sex, age, birth date, deprivation index, 16 PCs
PPM011138 PGS002033
(portability-ldpred2_278)
PSS008398|
Greater Middle Eastern Ancestry|
1,200 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0801 [0.0232, 0.1366] sex, age, birth date, deprivation index, 16 PCs
PPM011139 PGS002033
(portability-ldpred2_278)
PSS008177|
South Asian Ancestry|
6,331 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0502 [0.0255, 0.0747] sex, age, birth date, deprivation index, 16 PCs
PPM011140 PGS002033
(portability-ldpred2_278)
PSS007963|
East Asian Ancestry|
1,810 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0109 [-0.0354, 0.0572] sex, age, birth date, deprivation index, 16 PCs
PPM011141 PGS002033
(portability-ldpred2_278)
PSS007744|
African Ancestry|
2,484 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0265 [-0.013, 0.0659] sex, age, birth date, deprivation index, 16 PCs
PPM011142 PGS002033
(portability-ldpred2_278)
PSS008848|
African Ancestry|
3,924 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0516 [0.0203, 0.0829] sex, age, birth date, deprivation index, 16 PCs
PPM011136 PGS002033
(portability-ldpred2_278)
PSS009069|
European Ancestry|
4,136 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Overweight, obesity and other hyperalimentation Partial Correlation (partial-r): 0.0523 [0.0218, 0.0827] sex, age, birth date, deprivation index, 16 PCs
PPM016326 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Atrial fibrillation OR: 1.45
β: 0.37 (0.07)
PPM016327 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Ischemic Heart Disease OR: 1.35
β: 0.3 (0.06)
PPM016328 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Gastrojejunal ulcer OR: 6.42
β: 1.86 (0.38)
PPM016482 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cholelithiasis OR: 1.5
β: 0.4 (0.1)
PPM016499 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Barrett's esophagus OR: 2.2
β: 0.8 (0.2)
PPM016480 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic pulmonary heart disease OR: 1.6
β: 0.4 (0.1)
PPM016485 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Other chronic ischemic heart disease, unspecified OR: 1.4
β: 0.4 (0.1)
PPM016486 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Osteoarthritis; localized OR: 1.3
β: 0.3 (0.1)
PPM016487 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic ulcer of leg or foot OR: 1.6
β: 0.5 (0.1)
PPM016481 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Postoperative infection OR: 1.6
β: 0.5 (0.1)
PPM016496 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Myocardial infarction OR: 1.4
β: 0.3 (0.1)
PPM016497 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hyperlipidemia OR: 1.2
β: 0.2 (0.1)
PPM016423 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Shock OR: 1.58
β: 0.46 (0.15)
PPM016424 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Candidiasis of skin and nails OR: 1.7
β: 0.53 (0.17)
PPM016425 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Depression OR: 1.2
β: 0.18 (0.06)
PPM016426 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Nonspecific chest pain OR: 1.17
β: 0.16 (0.05)
PPM016427 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Nonrheumatic aortic valve disorders OR: 1.31
β: 0.27 (0.09)
PPM016428 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Ingrowing nail OR: 1.46
β: 0.38 (0.12)
PPM016429 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Sleep disorders OR: 1.21
β: 0.19 (0.06)
PPM016430 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic kidney disease, Stage I or II OR: 1.49
β: 0.4 (0.13)
PPM016431 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hypoventilation OR: 1.64
β: 0.49 (0.17)
PPM016432 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Gouty arthropathy OR: 1.52
β: 0.42 (0.14)
PPM016433 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Heart failure NOS OR: 1.35
β: 0.3 (0.1)
PPM016435 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Arthropathy associated with neurological disorders OR: 2.76
β: 1.01 (0.35)
PPM016436 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Coagulation defects OR: 1.27
β: 0.24 (0.08)
PPM016437 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Osteoarthrosis involving more than one site, but not specified as generalized OR: 1.5
β: 0.4 (0.14)
PPM016438 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Liver abscess and sequelae of chronic liver disease OR: 1.65
β: 0.5 (0.17)
PPM016439 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hypothyroidism OR: 1.21
β: 0.19 (0.07)
PPM016440 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Bursitis OR: 1.37
β: 0.31 (0.11)
PPM016441 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Umbilical hernia OR: 1.54
β: 0.43 (0.15)
PPM016442 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cardiomyopathy OR: 1.29
β: 0.26 (0.09)
PPM016443 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Calcaneal spur; Exostosis NOS OR: 1.39
β: 0.33 (0.12)
PPM016444 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Pulmonary embolism and infarction, acute OR: 1.43
β: 0.35 (0.13)
PPM016445 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic pain OR: 1.31
β: 0.27 (0.1)
PPM016446 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Spondylosis without myelopathy OR: 1.2
β: 0.19 (0.07)
PPM016447 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Obesity OR: 3.5
β: 1.2 (0.1)
PPM016449 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Type 2 diabetes OR: 2.0
β: 0.7 (0.1)
PPM016450 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Sleep apnea OR: 2.2
β: 0.8 (0.1)
PPM016451 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Diabetes mellitus OR: 1.9
β: 0.7 (0.1)
PPM016452 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hypertension OR: 1.8
β: 0.6 (0.1)
PPM016453 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Essential hypertension OR: 1.8
β: 0.6 (0.1)
PPM016454 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Other chronic nonalcoholic liver disease OR: 2.2
β: 0.8 (0.1)
PPM016455 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic liver disease and cirrhosis OR: 2.1
β: 0.7 (0.1)
PPM016456 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Edema OR: 1.6
β: 0.4 (0.1)
PPM016457 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Type 1 diabetes OR: 1.9
β: 0.6 (0.1)
PPM016459 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Other disorders of intestine OR: 1.7
β: 0.5 (0.1)
PPM016460 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Acute renal failure OR: 1.6
β: 0.5 (0.1)
PPM016461 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Osteoarthrosis OR: 1.4
β: 0.4 (0.1)
PPM016462 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Osteoarthrosis NOS OR: 1.4
β: 0.4 (0.1)
PPM016463 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Respiratory failure, insufficiency, arrest OR: 1.6
β: 0.5 (0.1)
PPM016464 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Osteoarthrosis, localized, primary OR: 1.7
β: 0.5 (0.1)
PPM016465 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Renal failure OR: 1.4
β: 0.4 (0.1)
PPM016466 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Shortness of breath OR: 1.4
β: 0.3 (0.1)
PPM016467 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Coronary atherosclerosis OR: 1.4
β: 0.3 (0.1)
PPM016468 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cardiomegaly OR: 1.5
β: 0.4 (0.1)
PPM016469 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Congestive heart failure OR: 1.5
β: 0.4 (0.1)
PPM016471 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Respiratory failure OR: 1.7
β: 0.5 (0.1)
PPM016472 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic venous insufficiency OR: 1.8
β: 0.6 (0.1)
PPM016473 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Pulmonary heart disease OR: 1.5
β: 0.4 (0.1)
PPM016474 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Atrial fibrillation and flutter OR: 1.4
β: 0.4 (0.1)
PPM016475 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Type 2 diabetes with renal manifestations OR: 1.8
β: 0.6 (0.1)
PPM016476 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Ischemic Heart Disease OR: 1.4
β: 0.3 (0.1)
PPM016477 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic ulcer of skin OR: 1.6
β: 0.4 (0.1)
PPM016478 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Superficial cellulitis and abscess OR: 1.3
β: 0.3 (0.1)
PPM016479 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Type 2 diabetes with ophthalmic manifestations OR: 1.9
β: 0.6 (0.1)
PPM016484 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Pulmonary collapse; interstitial and compensatory emphysema OR: 1.4
β: 0.3 (0.1)
PPM016488 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Spinal stenosis of lumbar region OR: 1.5
β: 0.4 (0.1)
PPM016489 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic renal failure OR: 1.3
β: 0.3 (0.1)
PPM016490 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Diabetic retinopathy OR: 1.7
β: 0.6 (0.1)
PPM016491 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cardiac dysrhythmias OR: 1.3
β: 0.2 (0.1)
PPM016492 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Ventral hernia OR: 1.8
β: 0.6 (0.1)
PPM016494 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Spinal stenosis OR: 1.4
β: 0.3 (0.1)
PPM016495 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Iron deficiency anemias OR: 1.3
β: 0.3 (0.1)
PPM016498 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hypertensive heart and/or renal disease OR: 1.3
β: 0.3 (0.1)
PPM016502 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Gout OR: 1.4
β: 0.4 (0.1)
PPM016503 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Polycystic ovaries OR: 2.7
β: 1.0 (0.3)
PPM016504 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Bacterial infection NOS OR: 1.3
β: 0.3 (0.1)
PPM016505 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Disorders of adrenal glands OR: 1.6
β: 0.5 (0.1)
PPM016506 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Disorders of lipoid metabolism OR: 1.2
β: 0.2 (0.1)
PPM016507 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Diabetes type 2 with peripheral circulatory disorders OR: 1.8
β: 0.6 (0.2)
PPM016508 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Type 1 diabetes with neurological manifestations OR: 2.0
β: 0.7 (0.2)
PPM016509 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Other forms of chronic heart disease OR: 1.3
β: 0.3 (0.1)
PPM016510 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic Kidney Disease, Stage IV OR: 1.5
β: 0.4 (0.1)
PPM016511 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Ovarian dysfunction OR: 2.2
β: 0.8 (0.2)
PPM016513 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Iron deficiency anemias, unspecified or not due to blood loss OR: 1.3
β: 0.3 (0.1)
PPM016514 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Gout and other crystal arthropathies OR: 1.4
β: 0.3 (0.1)
PPM016515 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Intervertebral disc disorders OR: 1.2
β: 0.2 (0.1)
PPM016516 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Mood disorders OR: 1.2
β: 0.2 (0.1)
PPM016517 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hypothyroidism OR: 1.3
β: 0.2 (0.1)
PPM016518 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Unstable angina (intermediate coronary syndrome) OR: 1.4
β: 0.3 (0.1)
PPM016519 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cholelithiasis with other cholecystitis OR: 1.6
β: 0.5 (0.1)
PPM016520 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hypertensive chronic kidney disease OR: 1.3
β: 0.2 (0.1)
PPM016521 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Acute pulmonary heart disease OR: 1.5
β: 0.4 (0.1)
PPM016522 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Depression OR: 1.2
β: 0.2 (0.1)
PPM016523 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Nonspecific chest pain OR: 1.2
β: 0.2 (0.1)
PPM016525 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Sleep disorders OR: 1.2
β: 0.2 (0.1)
PPM016526 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hypoventilation OR: 1.6
β: 0.5 (0.2)
PPM016527 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Heart failure NOS OR: 1.4
β: 0.3 (0.1)
PPM016528 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hypothyroidism OR: 1.2
β: 0.2 (0.1)
PPM016529 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Umbilical hernia OR: 1.5
β: 0.4 (0.2)
PPM016530 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cardiomyopathy OR: 1.3
β: 0.3 (0.1)
PPM016531 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Calcaneal spur; Exostosis OR: 1.4
β: 0.3 (0.1)
PPM016532 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Pulmonary embolism and infarction, acute OR: 1.4
β: 0.4 (0.1)
PPM016533 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Spondylosis without myelopathy OR: 1.2
β: 0.2 (0.1)
PPM016399 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic Kidney Disease, Stage IV OR: 1.54
β: 0.43 (0.13)
PPM016329 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cardiac pacemaker/device in situ OR: 1.68
β: 0.52 (0.1)
PPM016284 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: BMI : 0.0192
PPM016286 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Morbid obesity OR: 6.08
β: 1.8 (0.08)
PPM016287 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Obesity OR: 3.48
β: 1.25 (0.06)
PPM016289 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Bariatric surgery OR: 7.85
β: 2.06 (0.15)
PPM016290 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Type 2 diabetes OR: 1.99
β: 0.69 (0.06)
PPM016291 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Sleep apnea OR: 2.24
β: 0.81 (0.07)
PPM016292 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Diabetes mellitus OR: 1.95
β: 0.67 (0.06)
PPM016293 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Eating disorder OR: 6.44
β: 1.86 (0.17)
PPM016294 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hypertension OR: 1.82
β: 0.6 (0.06)
PPM016295 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Obstructive sleep apnea OR: 2.13
β: 0.76 (0.08)
PPM016296 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Essential hypertension OR: 1.79
β: 0.58 (0.06)
PPM016297 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Gastrointestinal complications OR: 2.72
β: 1.0 (0.12)
PPM016298 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Other chronic nonalcoholic liver disease OR: 2.17
β: 0.77 (0.09)
PPM016300 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Insulin pump user OR: 2.15
β: 0.77 (0.1)
PPM016301 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Edema OR: 1.56
β: 0.44 (0.06)
PPM016302 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Type 1 diabetes OR: 1.9
β: 0.64 (0.09)
PPM016303 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Type 2 diabetes with neurological manifestations OR: 1.96
β: 0.67 (0.1)
PPM016304 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Localized adiposity OR: 5.12
β: 1.63 (0.25)
PPM016305 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Other disorders of intestine OR: 1.67
β: 0.51 (0.08)
PPM016306 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Acute renal failure OR: 1.61
β: 0.47 (0.07)
PPM016307 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Osteoarthrosis OR: 1.45
β: 0.37 (0.06)
PPM016308 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Osteoarthrosis NOS OR: 1.45
β: 0.37 (0.06)
PPM016310 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Osteoarthrosis, localized, primary OR: 1.66
β: 0.51 (0.09)
PPM016311 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Renal failure OR: 1.43
β: 0.36 (0.06)
PPM016312 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Shortness of breath OR: 1.38
β: 0.32 (0.06)
PPM016313 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Polyneuropathy in diabetes OR: 1.87
β: 0.63 (0.11)
PPM016314 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Encounter for long-term (current) use of anticoagulants OR: 1.48
β: 0.4 (0.07)
PPM016315 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Coronary atherosclerosis OR: 1.42
β: 0.35 (0.06)
PPM016316 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cardiomegaly OR: 1.51
β: 0.41 (0.07)
PPM016317 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Congestive heart failure (CHF) NOS OR: 1.49
β: 0.4 (0.07)
PPM016318 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Congestive heart failure; nonhypertensive OR: 1.45
β: 0.37 (0.07)
PPM016319 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Respiratory failure OR: 1.68
β: 0.52 (0.1)
PPM016321 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Pulmonary heart disease OR: 1.52
β: 0.42 (0.08)
PPM016322 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Heart failure with reduced EF [Systolic or combined heart failure] OR: 1.72
β: 0.54 (0.1)
PPM016323 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Atrial fibrillation and flutter OR: 1.45
β: 0.37 (0.07)
PPM016324 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Type 2 diabetes with renal manifestations OR: 1.76
β: 0.57 (0.11)
PPM016325 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Panniculitis OR: 4.3
β: 1.46 (0.29)
PPM016336 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Incisional hernia OR: 2.14
β: 0.76 (0.16)
PPM016337 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Septicemia OR: 1.53
β: 0.43 (0.09)
PPM016338 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic pulmonary heart disease OR: 1.56
β: 0.44 (0.1)
PPM016339 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Postoperative infection OR: 1.64
β: 0.49 (0.11)
PPM016340 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Other arthropathies OR: 1.39
β: 0.33 (0.07)
PPM016341 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cholelithiasis OR: 1.53
β: 0.43 (0.09)
PPM016343 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Dysmetabolic syndrome X OR: 2.4
β: 0.88 (0.19)
PPM016344 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cholelithiasis and cholecystitis OR: 1.49
β: 0.4 (0.09)
PPM016345 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Pulmonary collapse; interstitial and compensatory emphysema OR: 1.38
β: 0.32 (0.07)
PPM016346 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Other chronic ischemic heart disease, unspecified OR: 1.43
β: 0.35 (0.08)
PPM016347 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Osteoarthritis; localized OR: 1.35
β: 0.3 (0.07)
PPM016348 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic ulcer of leg or foot OR: 1.64
β: 0.49 (0.11)
PPM016349 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cellulitis and abscess of leg, except foot OR: 1.57
β: 0.45 (0.1)
PPM016350 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Spinal stenosis of lumbar region OR: 1.52
β: 0.42 (0.1)
PPM016351 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cardiac pacemaker in situ OR: 1.66
β: 0.51 (0.12)
PPM016352 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic renal failure [CKD] OR: 1.34
β: 0.3 (0.07)
PPM016354 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Dependence on respirator [Ventilator] or supplemental oxygen OR: 2.04
β: 0.71 (0.17)
PPM016355 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cardiac defibrillator in situ OR: 1.87
β: 0.63 (0.15)
PPM016356 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cardiac dysrhythmias OR: 1.25
β: 0.22 (0.05)
PPM016357 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Osteomyelitis OR: 1.91
β: 0.65 (0.15)
PPM016358 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Swelling of limb OR: 1.34
β: 0.29 (0.07)
PPM016359 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Asthma OR: 1.32
β: 0.28 (0.07)
PPM016361 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Ventral hernia OR: 1.84
β: 0.61 (0.15)
PPM016362 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Decubitus ulcer OR: 1.75
β: 0.56 (0.14)
PPM016363 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Pulmonary congestion and hypostasis OR: 1.56
β: 0.44 (0.11)
PPM016364 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Spinal stenosis OR: 1.41
β: 0.35 (0.09)
PPM016365 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Iron deficiency anemias OR: 1.34
β: 0.29 (0.07)
PPM016366 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Wheezing OR: 1.52
β: 0.42 (0.1)
PPM016367 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Intestinal malabsorption (non-celiac) OR: 2.08
β: 0.73 (0.18)
PPM016368 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Portal hypertension OR: 2.55
β: 0.94 (0.24)
PPM016369 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Myocardial infarction OR: 1.35
β: 0.3 (0.08)
PPM016370 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Fluid overload OR: 1.52
β: 0.42 (0.11)
PPM016371 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hyperlipidemia OR: 1.25
β: 0.22 (0.06)
PPM016372 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hypertensive heart and/or renal disease OR: 1.3
β: 0.26 (0.07)
PPM016373 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic tonsillitis and adenoiditis OR: 2.02
β: 0.7 (0.18)
PPM016374 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Abnormal weight gain OR: 1.51
β: 0.41 (0.11)
PPM016375 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Dermatophytosis of nail OR: 1.38
β: 0.32 (0.09)
PPM016376 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Barrett's esophagus OR: 2.19
β: 0.78 (0.21)
PPM016377 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Degeneration of intervertebral disc OR: 1.3
β: 0.27 (0.07)
PPM016379 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Heart failure with preserved EF [Diastolic heart failure] OR: 1.49
β: 0.4 (0.11)
PPM016380 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Deep vein thrombosis OR: 1.52
β: 0.42 (0.11)
PPM016381 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Other symptoms of respiratory system OR: 1.21
β: 0.19 (0.05)
PPM016382 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Gout OR: 1.42
β: 0.35 (0.1)
PPM016383 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Polycystic ovaries OR: 2.7
β: 0.99 (0.27)
PPM016384 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Sinoatrial node dysfunction (Bradycardia) OR: 1.62
β: 0.48 (0.13)
PPM016385 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Bacterial infection NOS OR: 1.31
β: 0.27 (0.07)
PPM016386 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Disorders of adrenal glands OR: 1.63
β: 0.49 (0.13)
PPM016387 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Disorders of lipoid metabolism OR: 1.23
β: 0.21 (0.06)
PPM016388 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Mixed hyperlipidemia OR: 1.31
β: 0.27 (0.08)
PPM016389 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Corns and callosities OR: 1.49
β: 0.4 (0.11)
PPM016390 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Acquired acanthosis nigricans OR: 3.19
β: 1.16 (0.32)
PPM016391 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Paroxysmal ventricular tachycardia OR: 1.51
β: 0.41 (0.12)
PPM016392 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Atrial flutter OR: 1.51
β: 0.41 (0.12)
PPM016393 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Vitamin deficiency OR: 1.28
β: 0.24 (0.07)
PPM016395 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Osteomyelitis, periostitis, and other infections involving bone OR: 1.62
β: 0.48 (0.14)
PPM016396 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Dermatophytosis OR: 1.29
β: 0.25 (0.07)
PPM016397 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Type 1 diabetes with neurological manifestations OR: 1.99
β: 0.69 (0.2)
PPM016398 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Other forms of chronic heart disease OR: 1.34
β: 0.29 (0.08)
PPM016400 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Encounter for long-term (current) use of aspirin OR: 1.34
β: 0.29 (0.09)
PPM016401 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Ovarian dysfunction OR: 2.18
β: 0.78 (0.23)
PPM016402 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Acquired foot deformities OR: 1.32
β: 0.28 (0.08)
PPM016404 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Gout and other crystal arthropathies OR: 1.35
β: 0.3 (0.09)
PPM016405 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Intervertebral disc disorders OR: 1.24
β: 0.22 (0.06)
PPM016406 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Mood disorders OR: 1.21
β: 0.19 (0.06)
PPM016407 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hypothyroidism NOS OR: 1.25
β: 0.23 (0.07)
PPM016408 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Arrhythmia (cardiac) NOS OR: 1.26
β: 0.23 (0.07)
PPM016409 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Dermatophytosis / Dermatomycosis OR: 1.26
β: 0.23 (0.07)
PPM016410 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Unstable angina (intermediate coronary syndrome) OR: 1.35
β: 0.3 (0.09)
PPM016411 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Thoracic or lumbosacral neuritis or radiculitis, unspecified OR: 1.33
β: 0.28 (0.09)
PPM016412 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Other dyspnea OR: 1.2
β: 0.18 (0.06)
PPM016413 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Abnormal coagulation profile OR: 1.52
β: 0.42 (0.13)
PPM016414 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cholelithiasis with other cholecystitis OR: 1.61
β: 0.47 (0.15)
PPM016415 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Dislocation OR: 1.37
β: 0.31 (0.1)
PPM016416 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Vitamin D deficiency OR: 1.26
β: 0.23 (0.07)
PPM016417 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hypertensive chronic kidney disease OR: 1.28
β: 0.24 (0.08)
PPM016418 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Flat foot OR: 1.61
β: 0.48 (0.15)
PPM016330 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Other venous embolism and thrombosis OR: 1.47
β: 0.39 (0.08)
PPM016331 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic ulcer of skin OR: 1.55
β: 0.44 (0.09)
PPM016332 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Non-healing surgical wound OR: 3.16
β: 1.15 (0.23)
PPM016333 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Arthropathy NOS OR: 1.43
β: 0.36 (0.07)
PPM016334 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Superficial cellulitis and abscess OR: 1.35
β: 0.3 (0.06)
PPM016419 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hypertensive heart disease OR: 1.35
β: 0.3 (0.1)
PPM016420 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic obstructive asthma OR: 1.56
β: 0.45 (0.14)
PPM016421 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Respiratory abnormalities OR: 1.37
β: 0.32 (0.1)
PPM016422 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Acute pulmonary heart disease OR: 1.46
β: 0.38 (0.12)
PPM016434 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Hereditary and idiopathic peripheral neuropathy OR: 1.3
β: 0.26 (0.09)
PPM016448 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Overweight, obesity and other hyperalimentation OR: 3.0
β: 1.1 (0.1)
PPM016458 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Type 2 diabetes with neurological manifestations OR: 2.0
β: 0.7 (0.1)
PPM016470 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Congestive heart failure; nonhypertensive OR: 1.5
β: 0.4 (0.1)
PPM016483 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Cholelithiasis and cholecystitis OR: 1.5
β: 0.4 (0.1)
PPM016493 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Pulmonary congestion and hypostasis OR: 1.6
β: 0.4 (0.1)
PPM016500 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Degeneration of intervertebral disc OR: 1.3
β: 0.3 (0.1)
PPM016501 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Other symptoms of respiratory system OR: 1.2
β: 0.2 (0.1)
PPM016512 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Acquired foot deformities OR: 1.3
β: 0.3 (0.1)
PPM016524 PGS003400
(PRS97_obesity)
PSS010096|
Multi-ancestry (including European)|
65,174 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Nonrheumatic aortic valve disorders OR: 1.3
β: 0.3 (0.1)
PPM016288 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Overweight, obesity and other hyperalimentation OR: 3.02
β: 1.1 (0.05)
PPM016299 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic liver disease and cirrhosis OR: 2.1
β: 0.74 (0.09)
PPM016309 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Respiratory failure, insufficiency, arrest OR: 1.63
β: 0.49 (0.08)
PPM016320 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Chronic venous insufficiency [CVI] OR: 1.76
β: 0.57 (0.11)
PPM016335 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Type 2 diabetes with ophthalmic manifestations OR: 1.91
β: 0.65 (0.13)
PPM016342 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Other disorders of the kidney and ureters OR: 1.37
β: 0.31 (0.07)
PPM016353 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Diabetic retinopathy OR: 1.74
β: 0.55 (0.13)
PPM016360 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin OR: 1.41
β: 0.34 (0.08)
PPM016378 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Infection/inflammation of internal prosthetic device; implant; and graft OR: 1.57
β: 0.45 (0.12)
PPM016394 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Diabetes type 2 with peripheral circulatory disorders OR: 1.84
β: 0.61 (0.17)
PPM016403 PGS003400
(PRS97_obesity)
PSS010097|
Multi-ancestry (including European)|
405,432 individuals
PGP000416 |
Robinson JR et al. Obesity (Silver Spring) (2022)
Reported Trait: Iron deficiency anemias, unspecified or not due to blood loss OR: 1.3
β: 0.27 (0.08)
PPM019108 PGS003959
(GRS940_obesity)
PSS011184|
Multi-ancestry (including European)|
27,429 individuals
PGP000507 |
Liu X et al. Clin Nutr (2023)
Reported Trait: Abdominal obesity β: 0.078 (0.019) Age, sex, race, centres, education, Townsend deprivation index, household income, smoking, alcohol consumption, physical activity, sleep pattern, energy intake, and BMI, WC or BF% at baseline
PPM019109 PGS003959
(GRS940_obesity)
PSS011184|
Multi-ancestry (including European)|
27,429 individuals
PGP000507 |
Liu X et al. Clin Nutr (2023)
Reported Trait: Body mass index increase β: 0.157 (0.013) Age, sex, race, centres, education, Townsend deprivation index, household income, smoking, alcohol consumption, physical activity, sleep pattern, energy intake, and BMI, WC or BF% at baseline
PPM019110 PGS003959
(GRS940_obesity)
PSS011184|
Multi-ancestry (including European)|
27,429 individuals
PGP000507 |
Liu X et al. Clin Nutr (2023)
Reported Trait: Wasit circumference increase β: 0.213 (0.039) Age, sex, race, centres, education, Townsend deprivation index, household income, smoking, alcohol consumption, physical activity, sleep pattern, energy intake, and BMI, WC or BF% at baseline
PPM019111 PGS003959
(GRS940_obesity)
PSS011184|
Multi-ancestry (including European)|
27,429 individuals
PGP000507 |
Liu X et al. Clin Nutr (2023)
Reported Trait: Body fat percentage increase β: 0.042 (0.021) Age, sex, race, centres, education, Townsend deprivation index, household income, smoking, alcohol consumption, physical activity, sleep pattern, energy intake, and BMI, WC or BF% at baseline
PPM019112 PGS003959
(GRS940_obesity)
PSS011184|
Multi-ancestry (including European)|
27,429 individuals
PGP000507 |
Liu X et al. Clin Nutr (2023)
Reported Trait: Obesity with sulfur microbial diet score Hazard ratio (HR, Q4 sulphur microbial diet score and high PRS vs. Q1 sulphur microbial diet score and low PRS): 1.74 [1.33, 2.29] age, sex, race, centers, household income, Townsend deprivation index, smoking, alcohol consumption, physical activity, sleep pattern, energy intake and body mass index or waist circumstance
PPM019113 PGS003959
(GRS940_obesity)
PSS011184|
Multi-ancestry (including European)|
27,429 individuals
PGP000507 |
Liu X et al. Clin Nutr (2023)
Reported Trait: Abdominal obesity with sulfur microbial diet score Hazard ratio (HR, Q4 sulphur microbial diet score and high PRS vs. Q1 sulphur microbial diet score and low PRS): 1.41 [1.17, 1.71] age, sex, race, centers, household income, Townsend deprivation index, smoking, alcohol consumption, physical activity, sleep pattern, energy intake and body mass index or waist circumstance
PPM019107 PGS003959
(GRS940_obesity)
PSS011184|
Multi-ancestry (including European)|
27,429 individuals
PGP000507 |
Liu X et al. Clin Nutr (2023)
Reported Trait: Obesity β: 0.149 (0.028) Age, sex, race, centres, education, Townsend deprivation index, household income, smoking, alcohol consumption, physical activity, sleep pattern, energy intake, and BMI, WC or BF% at baseline

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008398 1,200 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009295 20,000 individuals European UK (+ Ireland) UKB
PSS009069 4,136 individuals European Poland (NE Europe) UKB
PSS008177 6,331 individuals South Asian India (South Asia) UKB
PSS004590
[
  • 536 cases
  • , 5,961 controls
]
African unspecified UKB
PSS004591
[
  • 27 cases
  • , 1,677 controls
]
East Asian UKB
PSS004592
[
  • 1,355 cases
  • , 23,550 controls
]
European non-white British ancestry UKB
PSS004593
[
  • 564 cases
  • , 7,267 controls
]
South Asian UKB
PSS004594
[
  • 4,477 cases
  • , 62,948 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS011184 27,429 individuals,
47.0 % Male samples
Mean = 55.3 years
Sd = 7.6 years
European, Not reported UKB
PSS008848 3,924 individuals African unspecified Nigeria (West Africa) UKB
PSS007963 1,810 individuals East Asian China (East Asia) UKB
PSS008623 6,660 individuals European Italy (South Europe) UKB
PSS010096 52,760 individuals European UKB
PSS010096 11,323 individuals African unspecified
(Black)
UKB
PSS010096 1,091 individuals Asian unspecified UKB
PSS010097 390,459 individuals European eMERGE
PSS010097 3,018 individuals African unspecified
(Black)
eMERGE
PSS010097 8,169 individuals Asian unspecified eMERGE
PSS010097 3,786 individuals Other eMERGE
PSS007744 2,484 individuals African American or Afro-Caribbean Carribean UKB